Overexpression of mitochondrial GPAT in rat hepatocytes leads to decreased fatty acid oxidation and increased glycerolipid biosynthesis

Journal of Lipid Research

Volumn 45, Issue 7, 2004, Pages 1279-1288

  Lindén, Daniel ^a,b   William Olsson, Lena ^a   Rhedin, Magdalena ^a   Asztély, Anna Karin ^a   Clapham, John C ^a   Schreyer, Sandra ^a  

^a ASTRAZENECA R AND D   (Sweden)

^b UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

Glycerol 3 phosphate acyltransferase; Obesity; Triglyceride

Indexed keywords

ACYL COENZYME A; ADENOVIRUS VECTOR; ASPARTIC ACID; FATTY ACID; GLYCEROL 3 PHOSPHATE ACYLTRANSFERASE; GLYCEROLIPID; GLYCINE; ISOENZYME; PHOSPHOLIPID; TRIACYLGLYCEROL;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOSYNTHESIS; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME LOCALIZATION; ENZYME MECHANISM; ENZYME REGULATION; FATTY ACID METABOLISM; FATTY ACID OXIDATION; FEMALE; GENE OVEREXPRESSION; LIPOGENESIS; LIVER MICROSOME; LIVER MITOCHONDRION; MITOCHONDRIAL MEMBRANE; NONHUMAN; OBESITY; PHOSPHOLIPID SYNTHESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT;

ACYL COENZYME A; ANIMALS; BINDING SITES; CELLS, CULTURED; FATTY ACIDS; GLYCERIDES; GLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASE; HEPATOCYTES; HYPERLIPIDEMIAS; MICE; MITOCHONDRIA, LIVER; MITOCHONDRIAL PROTEINS; OBESITY; OXIDATION-REDUCTION; PHOSPHOLIPIDS; RATS; TRANSFECTION;

EID: 3042569137     PISSN: 00222275     EISSN: None     Source Type: Journal    
DOI: 10.1194/jlr.M400010-JLR200     Document Type: Article

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