Cell-permeable ceramides increase basal glucose incorporation into triacylglycerols but decrease the stimulation by insulin in 3T3-L1 adipocytes

International Journal of Obesity

Volumn 27, Issue 1, 2003, Pages 31-39

  Mei, J ^a   Wang, C N ^a,b   O'Brien, L ^a   Brindley, D N ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

^b National Research Institute of Chinese Medicine   (Taiwan)

Author keywords

Fatty acid synthesis; Insulin resistance; Phosphatidylinositol 3 kinases; Triacylglycerol synthesis; Tumour necrosis factor

Indexed keywords

CERAMIDE; DEOXYGLUCOSE; FATTY ACID; GLUCOSE; GLUCOSE TRANSPORTER 1; GLYCEROL; INSULIN; MITOGEN ACTIVATED PROTEIN KINASE; N ACETYLSPHINGOSINE; N HEXANOYLSPHINGOSINE; P21 ACTIVATED KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOTRANSFERASE; PROTEIN KINASE B; PROTEIN P21; S6 KINASE; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ADIPOCYTE; ANIMAL CELL; ARTICLE; CELL CULTURE; CELL MEMBRANE PERMEABILITY; CELL STRAIN 3T3; CONTROLLED STUDY; CULTURE MEDIUM; ENZYME ACTIVATION; GLUCOSE METABOLISM; GLUCOSE TRANSPORT; INSULIN RESISTANCE; INSULIN SENSITIVITY; LIPID STORAGE; NONHUMAN; OBESITY; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

3T3 CELLS; ADIPOCYTES; ANIMALS; CERAMIDES; GLUCOSE; HYPOGLYCEMIC AGENTS; IMMUNOBLOTTING; INSULIN; LIPID METABOLISM; MICE; TRIGLYCERIDES; TUMOR NECROSIS FACTOR-ALPHA;

ANIMALIA;

EID: 0037261135     PISSN: 03070565     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.ijo.0802183     Document Type: Article

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