-
1
-
-
34249888775
-
-
Diabetes Genetics Initiative of Broad Institute of Harvard and MIT Lund University and Novartis Institute for Biomedical Research. Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. Science 2007;316:1331-1336
-
Diabetes Genetics Initiative of Broad Institute of Harvard and MIT Lund University and Novartis Institute for Biomedical Research. Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. Science 2007;316:1331-1336
-
-
-
-
2
-
-
34249895023
-
-
Zeggini E, Weedon MN, Lindgren CM, Frayling TM, Elliott KS, Lango H, Timpson NJ, Perry JRB, Rayner NW, Freathy RM, Barrett JC, Shields B, Morris AP, Ellard S, Groves CJ, Harries LW, Marchini JL, Owen KR, Knight B, Cardon LR, Walker M, Hitman GA, Morris AD, Doney ASF, The Wellcome Trust Case Control Consortium, McCarthy MI, Hattersley AT. Replication of genome-wide association signals in U.K. samples reveals risk loci for type 2 diabetes. Science 2007;316:1336-1341
-
Zeggini E, Weedon MN, Lindgren CM, Frayling TM, Elliott KS, Lango H, Timpson NJ, Perry JRB, Rayner NW, Freathy RM, Barrett JC, Shields B, Morris AP, Ellard S, Groves CJ, Harries LW, Marchini JL, Owen KR, Knight B, Cardon LR, Walker M, Hitman GA, Morris AD, Doney ASF, The Wellcome Trust Case Control Consortium, McCarthy MI, Hattersley AT. Replication of genome-wide association signals in U.K. samples reveals risk loci for type 2 diabetes. Science 2007;316:1336-1341
-
-
-
-
3
-
-
33847176604
-
A genome-wide association study identified novel risk loci for type 2 diabetes
-
Sladek R, Rocheleau G, Rung J, Dina C, Shen L, Serre D, Boutin P, Vincent D, Belisle A, Hadjadj S, Balkau B, Heude B, Charpentier G, Hudson TJ, Montpetit A, Pshezhetsky AV, Prentki M, Posner BI, Balding DJ, Meyre D, Polychronakos C, Froguel P. A genome-wide association study identified novel risk loci for type 2 diabetes. Nature 2007;445:881-885
-
(2007)
Nature
, vol.445
, pp. 881-885
-
-
Sladek, R.1
Rocheleau, G.2
Rung, J.3
Dina, C.4
Shen, L.5
Serre, D.6
Boutin, P.7
Vincent, D.8
Belisle, A.9
Hadjadj, S.10
Balkau, B.11
Heude, B.12
Charpentier, G.13
Hudson, T.J.14
Montpetit, A.15
Pshezhetsky, A.V.16
Prentki, M.17
Posner, B.I.18
Balding, D.J.19
Meyre, D.20
Polychronakos, C.21
Froguel, P.22
more..
-
4
-
-
34249828965
-
-
Steinthorsdottir V, Thorleifsson G, Reynisdottir I, Benediktsson R, Jonsdottir T, Walters GB, Styrkarsdottir U, Gretarsdottir S, Emilsson V, Ghosh S, Baker A, Snorradottir S, Bjarnason H, Ng MCY, Hansen T, Bagger Y, Wilensky RL, Reilly MP, Adeyemo A, Chen Y, Zhou J, Gudnason V, Chen G, Huang H, Lashley K, Doumatey A, So W-Y, Ma RCY, Andersen G, Borch-Johnsen K, Jorgensen T, van Vliet-Ostaptchouk JV, Hofker MH, Wijmenga C, Christiansen C, Rader DJ, Rotimi C, Gurney M, Chan JCN, Pedersen O, Sigurdsson G, Gulcher JR, Thorsteinsdottir U, Kong A, Stefansson K. A variant in CDKAL1 influences insulin response and risk of type 2 diabetes. Nat Genet 2007;39:770-775
-
Steinthorsdottir V, Thorleifsson G, Reynisdottir I, Benediktsson R, Jonsdottir T, Walters GB, Styrkarsdottir U, Gretarsdottir S, Emilsson V, Ghosh S, Baker A, Snorradottir S, Bjarnason H, Ng MCY, Hansen T, Bagger Y, Wilensky RL, Reilly MP, Adeyemo A, Chen Y, Zhou J, Gudnason V, Chen G, Huang H, Lashley K, Doumatey A, So W-Y, Ma RCY, Andersen G, Borch-Johnsen K, Jorgensen T, van Vliet-Ostaptchouk JV, Hofker MH, Wijmenga C, Christiansen C, Rader DJ, Rotimi C, Gurney M, Chan JCN, Pedersen O, Sigurdsson G, Gulcher JR, Thorsteinsdottir U, Kong A, Stefansson K. A variant in CDKAL1 influences insulin response and risk of type 2 diabetes. Nat Genet 2007;39:770-775
-
-
-
-
5
-
-
42349106044
-
Diabetes Genetics Replication and Meta-analysis (DIAGRAM) Consortium: Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes
-
Zeggini E, Scott LJ, Saxena R, Voight BF. Diabetes Genetics Replication and Meta-analysis (DIAGRAM) Consortium: meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Nat Genet 2008;40:638-645
-
(2008)
Nat Genet
, vol.40
, pp. 638-645
-
-
Zeggini, E.1
Scott, L.J.2
Saxena, R.3
Voight, B.F.4
-
6
-
-
34248594090
-
-
Frayling TM, Timpson NJ, Weedon MN, Zeggini E, Freathy RM, Lindgren CM, Perry JRB, Elliott KS, Lango H, Rayner NW, Shields B, Harries LW, Barrett JC, Ellard S, Groves CJ, Knight B, Patch A-M, Ness AR, Ebrahim S, Lawlor DA, Ring SM, Ben-Shlomo Y, Jarvelin M-R, Sovio U, Bennett AJ, Melzer D, Ferrucci L, Loos RJF, Barroso I, Wareham NJ, Karpe F, Owen KR, Cardon LR, Walker M, Hitman GA, Palmer CNA, Doney ASF, Morris AD, Smith GD, The Wellcome Trust Case Control Consortium, Hattersley AT, McCarthy MI. A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science 2007;316:889-894
-
Frayling TM, Timpson NJ, Weedon MN, Zeggini E, Freathy RM, Lindgren CM, Perry JRB, Elliott KS, Lango H, Rayner NW, Shields B, Harries LW, Barrett JC, Ellard S, Groves CJ, Knight B, Patch A-M, Ness AR, Ebrahim S, Lawlor DA, Ring SM, Ben-Shlomo Y, Jarvelin M-R, Sovio U, Bennett AJ, Melzer D, Ferrucci L, Loos RJF, Barroso I, Wareham NJ, Karpe F, Owen KR, Cardon LR, Walker M, Hitman GA, Palmer CNA, Doney ASF, Morris AD, Smith GD, The Wellcome Trust Case Control Consortium, Hattersley AT, McCarthy MI. A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science 2007;316:889-894
-
-
-
-
7
-
-
38649121127
-
-
Sanna S, Jackson AU, Nagaraja R, Willer CJ, Chen WM, Bonnycastle LL, Shen H, Timpson N, Lettre G, Usala G, Chines PS, Stringham HM, Scott LJ, Dei M, Lai S, Albai G, Crisponi L, Naitza S, Doheny KF, Pugh EW, Ben-Shlomo Y, Ebrahim S, Lawlor DA, Bergman RN, Watanabe RM, Uda M, Tuomilehto J, Coresh J, Hirschhorn JN, Shuldiner AR, Schlessinger D, Collins FS, Davey Smith G, Boerwinkle E, Cao A, Boehnke M, Abecasis GR, Mohlke KL. Common variants in the GDF5-UQCC region are associated with variation in human height. Nat Genet 2008;40:198-203
-
Sanna S, Jackson AU, Nagaraja R, Willer CJ, Chen WM, Bonnycastle LL, Shen H, Timpson N, Lettre G, Usala G, Chines PS, Stringham HM, Scott LJ, Dei M, Lai S, Albai G, Crisponi L, Naitza S, Doheny KF, Pugh EW, Ben-Shlomo Y, Ebrahim S, Lawlor DA, Bergman RN, Watanabe RM, Uda M, Tuomilehto J, Coresh J, Hirschhorn JN, Shuldiner AR, Schlessinger D, Collins FS, Davey Smith G, Boerwinkle E, Cao A, Boehnke M, Abecasis GR, Mohlke KL. Common variants in the GDF5-UQCC region are associated with variation in human height. Nat Genet 2008;40:198-203
-
-
-
-
8
-
-
38649125868
-
-
Willer CJ, Sanna S, Jackson AU, Scuteri A, Bonnycastle LL, Clarke R, Heath SC, Timpson NJ, Najjar SS, Stringham HM, Strait J, Duren WL, Maschio A, Busonero F, Mulas A, Albai G, Swift AJ, Morken MA, Narisu N, Bennett D, Parish S, Shen H, Galan P, Meneton P, Hercberg S, Zelenika D, Chen WM, Li Y, Scott LJ, Scheet PA, Sundvall J, Watanabe RM, Nagaraja R, Ebrahim S, Lawlor DA, Ben-Shlomo Y, Davey-Smith G, Shuldiner AR, Collins R, Bergman RN, Uda M, Tuomilehto J, Cao A, Collins FS, Lakatta E, Lathrop GM, Boehnke M, Schlessinger D, Mohlke KL, Abecasis GR. Newly identified loci that influence lipid concentrations and risk of coronary artery disease. Nat Genet 2008;40:161-169
-
Willer CJ, Sanna S, Jackson AU, Scuteri A, Bonnycastle LL, Clarke R, Heath SC, Timpson NJ, Najjar SS, Stringham HM, Strait J, Duren WL, Maschio A, Busonero F, Mulas A, Albai G, Swift AJ, Morken MA, Narisu N, Bennett D, Parish S, Shen H, Galan P, Meneton P, Hercberg S, Zelenika D, Chen WM, Li Y, Scott LJ, Scheet PA, Sundvall J, Watanabe RM, Nagaraja R, Ebrahim S, Lawlor DA, Ben-Shlomo Y, Davey-Smith G, Shuldiner AR, Collins R, Bergman RN, Uda M, Tuomilehto J, Cao A, Collins FS, Lakatta E, Lathrop GM, Boehnke M, Schlessinger D, Mohlke KL, Abecasis GR. Newly identified loci that influence lipid concentrations and risk of coronary artery disease. Nat Genet 2008;40:161-169
-
-
-
-
9
-
-
46749100599
-
-
Chen W-M, Erdos MR, Jackson AU, Saxena R, Sanna S, Silver KD, Timpson NJ, Hansen T, Orrú M, Piras MG, Bonnycastle LL, Willer CJ, Lyssenko V, Shen H, Kuusisto J, Ebrahim S, Sestu N, Duren WL, Spada MC, Stringham HM, Scott LJ, Olla N, Swift AJ, Najjar S, Mitchell BD, Lawlor DA, Davey-Smith G, Ben-Shlomo Y, Andersen G, Borch-Johnsen K, Jorgensen T, Saramies J, Valle TT, Buchanan TA, Shuldiner AR, Lakatta E, Bergman RN, Uda M, Tuomilehto J, Pedersen O, Cao A, Groop L, Mohlke KL, Laakso M, Schlessinger D, Collins FS, Altshuler D, Abecasis GR, Boehnke M, Scuteri A, Watanabe RM. Variations in the G6PC2/ ABCB11 genomic region are associated with fasting glucose levels. J Clin Invest 2008;118:2609-2628
-
Chen W-M, Erdos MR, Jackson AU, Saxena R, Sanna S, Silver KD, Timpson NJ, Hansen T, Orrú M, Piras MG, Bonnycastle LL, Willer CJ, Lyssenko V, Shen H, Kuusisto J, Ebrahim S, Sestu N, Duren WL, Spada MC, Stringham HM, Scott LJ, Olla N, Swift AJ, Najjar S, Mitchell BD, Lawlor DA, Davey-Smith G, Ben-Shlomo Y, Andersen G, Borch-Johnsen K, Jorgensen T, Saramies J, Valle TT, Buchanan TA, Shuldiner AR, Lakatta E, Bergman RN, Uda M, Tuomilehto J, Pedersen O, Cao A, Groop L, Mohlke KL, Laakso M, Schlessinger D, Collins FS, Altshuler D, Abecasis GR, Boehnke M, Scuteri A, Watanabe RM. Variations in the G6PC2/ ABCB11 genomic region are associated with fasting glucose levels. J Clin Invest 2008;118:2609-2628
-
-
-
-
10
-
-
44449091627
-
A polymorphism within the G6PC2 gene is associated with fasting plasma glucose levels
-
Bouatia-Naji N, Rocheleau G, Van Lommel L, Lemaire K, Schuit F, Cavalcanti-Proença C, Marchand M, Hartikainen AL, Sovio U, De Graeve F, Rung J, Vaxillaire M, Tichet J, Marre M, Balkau B, Weill J, Elliott P, Jarvelin M-R, Meyer D, Polychronakos C, Dina C, Sladek R, Froguel P. A polymorphism within the G6PC2 gene is associated with fasting plasma glucose levels. Science 2008;320:1085-1088
-
(2008)
Science
, vol.320
, pp. 1085-1088
-
-
Bouatia-Naji, N.1
Rocheleau, G.2
Van Lommel, L.3
Lemaire, K.4
Schuit, F.5
Cavalcanti-Proença, C.6
Marchand, M.7
Hartikainen, A.L.8
Sovio, U.9
De Graeve, F.10
Rung, J.11
Vaxillaire, M.12
Tichet, J.13
Marre, M.14
Balkau, B.15
Weill, J.16
Elliott, P.17
Jarvelin, M.-R.18
Meyer, D.19
Polychronakos, C.20
Dina, C.21
Sladek, R.22
Froguel, P.23
more..
-
11
-
-
44349142294
-
-
Loos RJ, Lindgren CM, Li S, Wheeler E, Zhao JH, Prokopenko I, Inouye M, Freathy RM, Attwood AP, Beckmann JS, Berndt SI, Jacobs KB, Chanock SJ, Hayes RB, Bergmann S, Bennett AJ, Bingham SA, Bochud M, Brown M, Cauchi S, Connell JM, Cooper C, Smith GD, Day I, Dina C, De S, Dermitzakis ET, Doney AS, Elliott KS, Elliott P, Evans DM, Sadaf F, I, Froguel P, Ghori J, Groves CJ, Gwilliam R, Hadley D, Hall AS, Hattersley AT, Hebebrand J, Heid IM, Lamina C, Gieger C, Illig T, Meitinger T, Wichmann HE, Herrera B, Hinney A, Hunt SE, Jarvelin MR, Johnson T, Jolley JD, Karpe F, Keniry A, Khaw KT, Luben RN, Mangino M, Marchini J, McArdle WL, McGinnis R, Meyre D, Munroe PB, Morris AD, Ness AR, Neville MJ, Nica AC, Ong KK, O'Rahilly S, Owen KR, Palmer CN, Papadakis K, Potter S, Pouta A, Qi L, Randall JC, Rayner NW, Ring SM, Sandhu MS, Scherag A, Sims MA, Song K, Soranzo N, Speliotes EK, Syddall HE, Teichmann SA, Timpson NJ, Tobias JH, Uda M, Vogel CI, Wallace C, Waterworth DM, Weedon MN, Willer CJ, Wrai
-
Loos RJ, Lindgren CM, Li S, Wheeler E, Zhao JH, Prokopenko I, Inouye M, Freathy RM, Attwood AP, Beckmann JS, Berndt SI, Jacobs KB, Chanock SJ, Hayes RB, Bergmann S, Bennett AJ, Bingham SA, Bochud M, Brown M, Cauchi S, Connell JM, Cooper C, Smith GD, Day I, Dina C, De S, Dermitzakis ET, Doney AS, Elliott KS, Elliott P, Evans DM, Sadaf F, I, Froguel P, Ghori J, Groves CJ, Gwilliam R, Hadley D, Hall AS, Hattersley AT, Hebebrand J, Heid IM, Lamina C, Gieger C, Illig T, Meitinger T, Wichmann HE, Herrera B, Hinney A, Hunt SE, Jarvelin MR, Johnson T, Jolley JD, Karpe F, Keniry A, Khaw KT, Luben RN, Mangino M, Marchini J, McArdle WL, McGinnis R, Meyre D, Munroe PB, Morris AD, Ness AR, Neville MJ, Nica AC, Ong KK, O'Rahilly S, Owen KR, Palmer CN, Papadakis K, Potter S, Pouta A, Qi L, Randall JC, Rayner NW, Ring SM, Sandhu MS, Scherag A, Sims MA, Song K, Soranzo N, Speliotes EK, Syddall HE, Teichmann SA, Timpson NJ, Tobias JH, Uda M, Vogel CI, Wallace C, Waterworth DM, Weedon MN, Willer CJ, Wraight, Yuan X, Zeggini E, Hirschhorn JN, Strachan DP, Ouwehand WH, Caulfield MJ, Samani NJ, Frayling TM, Vollenweider P, Waeber G, Mooser V, Deloukas P, McCarthy MI, Wareham NJ, Barroso I, Jacobs KB, Chanock SJ, Hayes RB, Lamina C, Gieger C, Illig T, Meitinger T, Wichmann HE, Kraft P, Hankinson SE, Hunter DJ, Hu FB, Lyon HN, Voight BF, Ridderstrale M, Groop L, Scheet P, Sanna S, Abecasis GR, Albai G, Nagaraja R, Schlessinger D, Jackson AU, Tuomilehto J, Collins FS, Boehnke M, Mohlke KL. Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat Genet 2008;40:768-775
-
-
-
-
12
-
-
42649139571
-
-
Weedon MN, Lango H, Lindgren CM, Wallace C, Evans DM, Mangino M, Freathy RM, Perry JR, Stevens S, Hall AS, Samani NJ, Shields B, Prokopenko I, Farrall M, Dominiczak A, Johnson T, Bergmann S, Beckmann JS, Vollenweider P, Waterworth DM, Mooser V, Palmer CN, Morris AD, Ouwehand WH, Zhao JH, Li S, Loos RJ, Barroso I, Deloukas P, Sandhu MS, Wheeler E, Soranzo N, Inouye M, Wareham NJ, Caulfield M, Munroe PB, Hattersley AT, McCarthy MI, Frayling TM. Genome-wide association analysis identifies 20 loci that influence adult height. Nat Genet 2008;40:575-583
-
Weedon MN, Lango H, Lindgren CM, Wallace C, Evans DM, Mangino M, Freathy RM, Perry JR, Stevens S, Hall AS, Samani NJ, Shields B, Prokopenko I, Farrall M, Dominiczak A, Johnson T, Bergmann S, Beckmann JS, Vollenweider P, Waterworth DM, Mooser V, Palmer CN, Morris AD, Ouwehand WH, Zhao JH, Li S, Loos RJ, Barroso I, Deloukas P, Sandhu MS, Wheeler E, Soranzo N, Inouye M, Wareham NJ, Caulfield M, Munroe PB, Hattersley AT, McCarthy MI, Frayling TM. Genome-wide association analysis identifies 20 loci that influence adult height. Nat Genet 2008;40:575-583
-
-
-
-
13
-
-
44349166252
-
Common genetic variation near MC4R is associated with waist circumference and insulin resistance
-
Chambers JC, Elliott P, Zabaneh D, Zhang W, Li Y, Froguel P, Balding D, Scott J, Kooner JS. Common genetic variation near MC4R is associated with waist circumference and insulin resistance. Nat Genet 2008;40:716-718
-
(2008)
Nat Genet
, vol.40
, pp. 716-718
-
-
Chambers, J.C.1
Elliott, P.2
Zabaneh, D.3
Zhang, W.4
Li, Y.5
Froguel, P.6
Balding, D.7
Scott, J.8
Kooner, J.S.9
-
14
-
-
54249088172
-
-
Orho-Melander M, Melander O, Guiducci C, Perez-Martinez P, Corella D, Roos C, Tewhey R, Rieder MJ, Hall J, Abecasis G, Tai ES, Welch C, Arnett DK, Lyssenko V, Lindholm E, Saxena R, de Bakker PI, Burtt N, Voight BF, Hirschhorn JN, Tucker KL, Hedner T, Tuomi T, Isomaa B, Eriksson KF, Taskinen MR, Wahlstrand B, Hughes TE, Parnell LD, Lai CQ, Berglund G, Peltonen L, Vartiainen E, Jousilahti P, Havulinna AS, Salomaa V, Nilsson P, Groop L, Altshuler D, Ordovas JM, Kathiresan S. Common missense variant in the glucokinase regulatory protein gene is associated with increased plasma triglyceride and C-reactive protein but lower fasting glucose concentrations. Diabetes 2008;57:3112-3121
-
Orho-Melander M, Melander O, Guiducci C, Perez-Martinez P, Corella D, Roos C, Tewhey R, Rieder MJ, Hall J, Abecasis G, Tai ES, Welch C, Arnett DK, Lyssenko V, Lindholm E, Saxena R, de Bakker PI, Burtt N, Voight BF, Hirschhorn JN, Tucker KL, Hedner T, Tuomi T, Isomaa B, Eriksson KF, Taskinen MR, Wahlstrand B, Hughes TE, Parnell LD, Lai CQ, Berglund G, Peltonen L, Vartiainen E, Jousilahti P, Havulinna AS, Salomaa V, Nilsson P, Groop L, Altshuler D, Ordovas JM, Kathiresan S. Common missense variant in the glucokinase regulatory protein gene is associated with increased plasma triglyceride and C-reactive protein but lower fasting glucose concentrations. Diabetes 2008;57:3112-3121
-
-
-
-
15
-
-
50949132578
-
The common P446L polymorphism in GCKR inversely modulates fasting glucose and triglyceride levels and reduces type 2 diabetes risk in the DESIR prospective general French population
-
Vaxillaire M, Cavalcanti-Proenca C, Dechaume A, Tichet J, Marre M, Balkau B, Froguel P. The common P446L polymorphism in GCKR inversely modulates fasting glucose and triglyceride levels and reduces type 2 diabetes risk in the DESIR prospective general French population. Diabetes 2008;57:2253-2257
-
(2008)
Diabetes
, vol.57
, pp. 2253-2257
-
-
Vaxillaire, M.1
Cavalcanti-Proenca, C.2
Dechaume, A.3
Tichet, J.4
Marre, M.5
Balkau, B.6
Froguel, P.7
-
16
-
-
58149163149
-
-
Kathiresan S, Willer CJ, Peloso GM, Demissie S, Musunuru K, Schadt EE, Kaplan L, Bennett D, Li Y, Tanaka T, Voight BF, Bonnycastle LL, Jackson AU, Crawford G, Surti A, Guiducci C, Burtt NP, Parish S, Clarke R, Zelenika D, Kubalanza KA, Morken MA, Scott LJ, Stringham HM, Galan P, Swift AJ, Kuusisto J, Bergman RN, Sundvall J, Laakso M, Ferrucci L, Scheet P, Sanna S, Uda M, Yang Q, Lunetta KL, Dupuis J, de Bakker PI, O'Donnell CJ, Chambers JC, Kooner JS, Hercberg S, Meneton P, Lakatta EG, Scuteri A, Schlessinger D, Tuomilehto J, Collins FS, Groop L, Altshuler D, Collins R, Lathrop GM, Melander O, Salomaa V, Peltonen L, Orho-Melander M, Ordovas JM, Boehnke M, Abecasis GR, Mohlke KL, Cupples LA. Common variants at 30 loci contribute to polygenic dyslipidemia. Nat Genet 2009;41:56-65
-
Kathiresan S, Willer CJ, Peloso GM, Demissie S, Musunuru K, Schadt EE, Kaplan L, Bennett D, Li Y, Tanaka T, Voight BF, Bonnycastle LL, Jackson AU, Crawford G, Surti A, Guiducci C, Burtt NP, Parish S, Clarke R, Zelenika D, Kubalanza KA, Morken MA, Scott LJ, Stringham HM, Galan P, Swift AJ, Kuusisto J, Bergman RN, Sundvall J, Laakso M, Ferrucci L, Scheet P, Sanna S, Uda M, Yang Q, Lunetta KL, Dupuis J, de Bakker PI, O'Donnell CJ, Chambers JC, Kooner JS, Hercberg S, Meneton P, Lakatta EG, Scuteri A, Schlessinger D, Tuomilehto J, Collins FS, Groop L, Altshuler D, Collins R, Lathrop GM, Melander O, Salomaa V, Peltonen L, Orho-Melander M, Ordovas JM, Boehnke M, Abecasis GR, Mohlke KL, Cupples LA. Common variants at 30 loci contribute to polygenic dyslipidemia. Nat Genet 2009;41:56-65
-
-
-
-
17
-
-
58149175143
-
-
Bouatia-Naji N, Bonnefond A, Cavalcanti-Proenca C, Sparso T, Holmkvist J, Marchand M, Delplanque J, Lobbens S, Rocheleau G, Durand E, De GF, Chevre JC, Borch-Johnsen K, Hartikainen AL, Ruokonen A, Tichet J, Marre M, Weill J, Heude B, Tauber M, Lemaire K, Schuit F, Elliott P, Jorgensen T, Charpentier G, Hadjadj S, Cauchi S, Vaxillaire M, Sladek R, Visvikis-Siest S, Balkau B, Levy-Marchal C, Pattou F, Meyre D, Blakemore AI, Jarvelin MR, Walley AJ, Hansen T, Dina C, Pedersen O, Froguel P. A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk. Nat Genet 2009;41:89-94
-
Bouatia-Naji N, Bonnefond A, Cavalcanti-Proenca C, Sparso T, Holmkvist J, Marchand M, Delplanque J, Lobbens S, Rocheleau G, Durand E, De GF, Chevre JC, Borch-Johnsen K, Hartikainen AL, Ruokonen A, Tichet J, Marre M, Weill J, Heude B, Tauber M, Lemaire K, Schuit F, Elliott P, Jorgensen T, Charpentier G, Hadjadj S, Cauchi S, Vaxillaire M, Sladek R, Visvikis-Siest S, Balkau B, Levy-Marchal C, Pattou F, Meyre D, Blakemore AI, Jarvelin MR, Walley AJ, Hansen T, Dina C, Pedersen O, Froguel P. A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk. Nat Genet 2009;41:89-94
-
-
-
-
18
-
-
58149156287
-
-
Prokopenko I, Langenberg C, Florez JC, Saxena R, Soranzo N, Thorleifsson G, Loos RJ, Manning AK, Jackson AU, Aulchenko Y, Potter SC, Erdos MR, Sanna S, Hottenga JJ, Wheeler E, Kaakinen M, Lyssenko V, Chen WM, Ahmadi K, Beckmann JS, Bergman RN, Bochud M, Bonnycastle LL, Buchanan TA, Cao A, Cervino A, Coin L, Collins FS, Crisponi L, de Geus EJ, Dehghan A, Deloukas P, Doney AS, Elliott P, Freimer N, Gateva V, Herder C, Hofman A, Hughes TE, Hunt S, Illig T, Inouye M, Isomaa B, Johnson T, Kong A, Krestyaninova M, Kuusisto J, Laakso M, Lim N, Lindblad U, Lindgren CM, McCann OT, Mohlke KL, Morris AD, Naitza S, Orru M, Palmer CN, Pouta A, Randall J, Rathmann W, Saramies J, Scheet P, Scott LJ, Scuteri A, Sharp S, Sijbrands E, Smit JH, Song K, Steinthorsdottir V, Stringham HM, Tuomi T, Tuomilehto J, Uitterlinden AG, Voight BF, Waterworth D, Wichmann HE, Willemsen G, Witteman JC, Yuan X, Zhao JH, Zeggini E, Schlessinger D, Sandhu M, Boomsma DI, Uda M, Spector TD, Penninx BW, Altshuler D, Vollenwe
-
Prokopenko I, Langenberg C, Florez JC, Saxena R, Soranzo N, Thorleifsson G, Loos RJ, Manning AK, Jackson AU, Aulchenko Y, Potter SC, Erdos MR, Sanna S, Hottenga JJ, Wheeler E, Kaakinen M, Lyssenko V, Chen WM, Ahmadi K, Beckmann JS, Bergman RN, Bochud M, Bonnycastle LL, Buchanan TA, Cao A, Cervino A, Coin L, Collins FS, Crisponi L, de Geus EJ, Dehghan A, Deloukas P, Doney AS, Elliott P, Freimer N, Gateva V, Herder C, Hofman A, Hughes TE, Hunt S, Illig T, Inouye M, Isomaa B, Johnson T, Kong A, Krestyaninova M, Kuusisto J, Laakso M, Lim N, Lindblad U, Lindgren CM, McCann OT, Mohlke KL, Morris AD, Naitza S, Orru M, Palmer CN, Pouta A, Randall J, Rathmann W, Saramies J, Scheet P, Scott LJ, Scuteri A, Sharp S, Sijbrands E, Smit JH, Song K, Steinthorsdottir V, Stringham HM, Tuomi T, Tuomilehto J, Uitterlinden AG, Voight BF, Waterworth D, Wichmann HE, Willemsen G, Witteman JC, Yuan X, Zhao JH, Zeggini E, Schlessinger D, Sandhu M, Boomsma DI, Uda M, Spector TD, Penninx BW, Altshuler D, Vollenweider P, Jarvelin MR, Lakatta E, Waeber G, Fox CS, Peltonen L, Groop LC, Mooser V, Cupples LA, Thorsteinsdottir U, Boehnke M, Barroso I, Van DC, Dupuis J, Watanabe RM, Stefansson K, McCarthy MI, Wareham NJ, Meigs JB, Abecasis GR. Variants in MTNR1B influence fasting glucose levels. Nat Genet 2009;41:77-81
-
-
-
-
19
-
-
58149163142
-
-
Willer CJ, Speliotes EK, Loos RJ, Li S, Lindgren CM, Heid IM, Berndt SI, Elliott AL, Jackson AU, Lamina C, Lettre G, Lim N, Lyon HN, McCarroll SA, Papadakis K, Qi L, Randall JC, Roccasecca RM, Sanna S, Scheet P, Weedon MN, Wheeler E, Zhao JH, Jacobs LC, Prokopenko I, Soranzo N, Tanaka T, Timpson NJ, Almgren P, Bennett A, Bergman RN, Bingham SA, Bonnycastle LL, Brown M, Burtt NP, Chines P, Coin L, Collins FS, Connell JM, Cooper C, Smith GD, Dennison EM, Deodhar P, Elliott P, Erdos MR, Estrada K, Evans DM, Gianniny L, Gieger C, Gillson CJ, Guiducci C, Hackett R, Hadley D, Hall AS, Havulinna AS, Hebebrand J, Hofman A, Isomaa B, Jacobs KB, Johnson T, Jousilahti P, Jovanovic Z, Khaw KT, Kraft P, Kuokkanen M, Kuusisto J, Laitinen J, Lakatta EG, Luan J, Luben RN, Mangino M, McArdle WL, Meitinger T, Mulas A, Munroe PB, Narisu N, Ness AR, Northstone K, O'Rahilly S, Purmann C, Rees MG, Ridderstrale M, Ring SM, Rivadeneira F, Ruokonen A, Sandhu MS, Saramies J, Scott LJ, Scuteri A, Silander K, Sim
-
Willer CJ, Speliotes EK, Loos RJ, Li S, Lindgren CM, Heid IM, Berndt SI, Elliott AL, Jackson AU, Lamina C, Lettre G, Lim N, Lyon HN, McCarroll SA, Papadakis K, Qi L, Randall JC, Roccasecca RM, Sanna S, Scheet P, Weedon MN, Wheeler E, Zhao JH, Jacobs LC, Prokopenko I, Soranzo N, Tanaka T, Timpson NJ, Almgren P, Bennett A, Bergman RN, Bingham SA, Bonnycastle LL, Brown M, Burtt NP, Chines P, Coin L, Collins FS, Connell JM, Cooper C, Smith GD, Dennison EM, Deodhar P, Elliott P, Erdos MR, Estrada K, Evans DM, Gianniny L, Gieger C, Gillson CJ, Guiducci C, Hackett R, Hadley D, Hall AS, Havulinna AS, Hebebrand J, Hofman A, Isomaa B, Jacobs KB, Johnson T, Jousilahti P, Jovanovic Z, Khaw KT, Kraft P, Kuokkanen M, Kuusisto J, Laitinen J, Lakatta EG, Luan J, Luben RN, Mangino M, McArdle WL, Meitinger T, Mulas A, Munroe PB, Narisu N, Ness AR, Northstone K, O'Rahilly S, Purmann C, Rees MG, Ridderstrale M, Ring SM, Rivadeneira F, Ruokonen A, Sandhu MS, Saramies J, Scott LJ, Scuteri A, Silander K, Sims MA, Song K, Stephens J, Stevens S, Stringham HM, Tung YC, Valle TT, Van Duijn CM, Vimaleswaran KS, Vollenweider P, Waeber G, Wallace C, Watanabe RM, Waterworth DM, Watkins N, Witteman JC, Zeggini E, Zhai G, Zillikens MC, Altshuler D, Caulfield MJ, Chanock SJ, Farooqi IS, Ferrucci L, Guralnik JM, Hattersley AT, Hu FB, Jarvelin MR, Laakso M, Mooser V, Ong KK, Ouwehand WH, Salomaa V, Samani NJ, Spector TD, Tuomi T, Tuomilehto J, Uda M, Uitterlinden AG, Wareham NJ, Deloukas P, Frayling TM, Groop LC, Hayes RB, Hunter DJ, Mohlke KL, Peltonen L, Schlessinger D, Strachan DP, Wichmann HE, McCarthy MI, Boehnke M, Barroso I, Abecasis GR, Hirschhorn JN. Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet 2009;41:25-34
-
-
-
-
20
-
-
58149163141
-
-
Thorleifsson G, Walters GB, Gudbjartsson DF, Steinthorsdottir V, Sulem P, Helgadottir A, Styrkarsdottir U, Gretarsdottir S, Thorlacius S, Jonsdottir I, Jonsdottir T, Olafsdottir EJ, Olafsdottir GH, Jonsson T, Jonsson F, Borch-Johnsen K, Hansen T, Andersen G, Jorgensen T, Lauritzen T, Aben KK, Verbeek AL, Roeleveld N, Kampman E, Yanek LR, Becker LC, Tryggvadottir L, Rafnar T, Becker DM, Gulcher J, Kiemeney LA, Pedersen O, Kong A, Thorsteinsdottir U, Stefansson K. Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity. Nat Genet 2009;41:18-24
-
Thorleifsson G, Walters GB, Gudbjartsson DF, Steinthorsdottir V, Sulem P, Helgadottir A, Styrkarsdottir U, Gretarsdottir S, Thorlacius S, Jonsdottir I, Jonsdottir T, Olafsdottir EJ, Olafsdottir GH, Jonsson T, Jonsson F, Borch-Johnsen K, Hansen T, Andersen G, Jorgensen T, Lauritzen T, Aben KK, Verbeek AL, Roeleveld N, Kampman E, Yanek LR, Becker LC, Tryggvadottir L, Rafnar T, Becker DM, Gulcher J, Kiemeney LA, Pedersen O, Kong A, Thorsteinsdottir U, Stefansson K. Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity. Nat Genet 2009;41:18-24
-
-
-
-
21
-
-
0029933511
-
A variation at position -30 of the β-cell glucokinase gene promoter is associated with reduced β-cell function in middle-aged Japanese-American men
-
Stone LM, Kahn SE, Fujimoto WY, Deeb SS, Porte D, Jr. A variation at position -30 of the β-cell glucokinase gene promoter is associated with reduced β-cell function in middle-aged Japanese-American men. Diabetes 1996;45:428
-
(1996)
Diabetes
, vol.45
, pp. 428
-
-
Stone, L.M.1
Kahn, S.E.2
Fujimoto, W.Y.3
Deeb, S.S.4
Porte Jr, D.5
-
22
-
-
25844513867
-
A -30G>A polymorphism of the β-cell-specific glucokinase promoter associates with hyperglycemia in the general population of whites
-
Rose CS, Urhammer SA, Glümer C, Borch-Johnsen K, Jørgensen T, Pedersen O, Hansen T. A -30G>A polymorphism of the β-cell-specific glucokinase promoter associates with hyperglycemia in the general population of whites. Diabetes 2005;54:3026-3031
-
(2005)
Diabetes
, vol.54
, pp. 3026-3031
-
-
Rose, C.S.1
Urhammer, S.A.2
Glümer, C.3
Borch-Johnsen, K.4
Jørgensen, T.5
Pedersen, O.6
Hansen, T.7
-
23
-
-
19944432769
-
Genetic regulation of birth weight and fasting glucose by a common polymorphism in the islet promoter of the glucokinase gene
-
Weedon MN, Frayling TM, Shields B, Knight B, Turner T, Metcalf BS, Voss L, Wilkin TJ, Mccarthy A, Ben-Shlomo Y, Davey-Smith G, Ring S, Jones R, Golding J, Byberg L, Mann V, Axelsson T, Syvänen AC, Leon D, Hattersley AT. Genetic regulation of birth weight and fasting glucose by a common polymorphism in the islet promoter of the glucokinase gene. Diabetes 2005;54:576-581
-
(2005)
Diabetes
, vol.54
, pp. 576-581
-
-
Weedon, M.N.1
Frayling, T.M.2
Shields, B.3
Knight, B.4
Turner, T.5
Metcalf, B.S.6
Voss, L.7
Wilkin, T.J.8
Mccarthy, A.9
Ben-Shlomo, Y.10
Davey-Smith, G.11
Ring, S.12
Jones, R.13
Golding, J.14
Byberg, L.15
Mann, V.16
Axelsson, T.17
Syvänen, A.C.18
Leon, D.19
Hattersley, A.T.20
more..
-
24
-
-
0026562918
-
Nonsense mutation in the glucokinase gene causes early-onset non-insulin-dependent diabetes mellitus
-
Vionnet N, Stoffel M, Takeda J, Yasuda K, Bell GI, Zouali H, Lesage S, Velho G, Iris F, Passa P, Froguel P, Cohen D. Nonsense mutation in the glucokinase gene causes early-onset non-insulin-dependent diabetes mellitus. Proc Natl Acad Sci 1992;356:721-722
-
(1992)
Proc Natl Acad Sci
, vol.356
, pp. 721-722
-
-
Vionnet, N.1
Stoffel, M.2
Takeda, J.3
Yasuda, K.4
Bell, G.I.5
Zouali, H.6
Lesage, S.7
Velho, G.8
Iris, F.9
Passa, P.10
Froguel, P.11
Cohen, D.12
-
25
-
-
0026639928
-
Human glucokinase gene: Isolation, characterization, and identification of two missense mutations linked to early-onset noninsulin-dependent (type 2) diabetes mellitus
-
Stoffel M, Froguel Ph, Takeda J, Zouali H, Vionnet N, Nishi S, Weber IT, Harrison RW, Pilkis SJ, Lesage S, Vaxillaire M, Velho G, Sun F, Iris F, Passa Ph, Cohen D, Bell GI. Human glucokinase gene: isolation, characterization, and identification of two missense mutations linked to early-onset noninsulin-dependent (type 2) diabetes mellitus. Proc Natl Acad Sci 1992;89:7698-7702
-
(1992)
Proc Natl Acad Sci
, vol.89
, pp. 7698-7702
-
-
Stoffel, M.1
Froguel, P.2
Takeda, J.3
Zouali, H.4
Vionnet, N.5
Nishi, S.6
Weber, I.T.7
Harrison, R.W.8
Pilkis, S.J.9
Lesage, S.10
Vaxillaire, M.11
Velho, G.12
Sun, F.13
Iris, F.14
Passa, P.15
Cohen, D.16
Bell, G.I.17
-
26
-
-
0027472126
-
Familial hyperglycemia due to mutations in glucokinase
-
Froguel Ph, Zouali H, Vionnet N, Velho G, Vaxillaire M, Sun F, Lesage S, Stoffel M, Takeda J, Passa P, Permutt MA, Beckmann JS, Bell GI, Cohen D. Familial hyperglycemia due to mutations in glucokinase. N Engl J Med 1993;328:697-702
-
(1993)
N Engl J Med
, vol.328
, pp. 697-702
-
-
Froguel, P.1
Zouali, H.2
Vionnet, N.3
Velho, G.4
Vaxillaire, M.5
Sun, F.6
Lesage, S.7
Stoffel, M.8
Takeda, J.9
Passa, P.10
Permutt, M.A.11
Beckmann, J.S.12
Bell, G.I.13
Cohen, D.14
-
27
-
-
0016873527
-
Futile cycles in the metabolism of glucose
-
Katz J, Rognstad R. Futile cycles in the metabolism of glucose. Curr Top Cell Regul 1976;10:237-289
-
(1976)
Curr Top Cell Regul
, vol.10
, pp. 237-289
-
-
Katz, J.1
Rognstad, R.2
-
28
-
-
0024356180
-
Evidence for the presence of glucose cycling in pancreatic islets of the ob/ob mouse
-
Khan A, Chandramouli V, Östenson C-G, Ahren B, Schumann WC, Löw H, Landau BR, Efendic S. Evidence for the presence of glucose cycling in pancreatic islets of the ob/ob mouse. J Biol Chem 1989;264:9732-9733
-
(1989)
J Biol Chem
, vol.264
, pp. 9732-9733
-
-
Khan, A.1
Chandramouli, V.2
Östenson, C.-G.3
Ahren, B.4
Schumann, W.C.5
Löw, H.6
Landau, B.R.7
Efendic, S.8
-
29
-
-
0025299154
-
Glucose cycling is markedly enhanced in pancreatic islets of obese hyperglycemic mice
-
Khan A, Chandramouli V, Ostenson CG, Berggren PO, Löw H, Landau BR, Efendic S. Glucose cycling is markedly enhanced in pancreatic islets of obese hyperglycemic mice. Endocrinology 1990;126:2413-2416
-
(1990)
Endocrinology
, vol.126
, pp. 2413-2416
-
-
Khan, A.1
Chandramouli, V.2
Ostenson, C.G.3
Berggren, P.O.4
Löw, H.5
Landau, B.R.6
Efendic, S.7
-
30
-
-
0025278457
-
Glucose cycling in islets from healthy and diabetic rats
-
Khan A, Chandramouli V, Ostenson CG, Löw H, Landau BR, Efendic S. Glucose cycling in islets from healthy and diabetic rats. Diabetes 1990;39:456-459
-
(1990)
Diabetes
, vol.39
, pp. 456-459
-
-
Khan, A.1
Chandramouli, V.2
Ostenson, C.G.3
Löw, H.4
Landau, B.R.5
Efendic, S.6
-
31
-
-
0030825183
-
Adenovirusmediated expression of the catalytic subunit of glucose-6-phosphatase in INS-1 cells
-
Trinh K, Minassian C, Lange AJ, O'Doherty RM, Newgard CB. Adenovirusmediated expression of the catalytic subunit of glucose-6-phosphatase in INS-1 cells. J Biol Chem 1997;272:24837-24842
-
(1997)
J Biol Chem
, vol.272
, pp. 24837-24842
-
-
Trinh, K.1
Minassian, C.2
Lange, A.J.3
O'Doherty, R.M.4
Newgard, C.B.5
-
32
-
-
0034067256
-
Stable overexpression of the glucose-6-phosphatase catalytic subunit attenuates glucose sensitivity of insulin secretion from a mouse pancreatic beta-cell line
-
Iizuka K, Nakjima H, Ono A, Okita K, Miyazaki J-I, Miyagawa J-I, Namba M, Hanafusa T, Matsuzawa Y. Stable overexpression of the glucose-6-phosphatase catalytic subunit attenuates glucose sensitivity of insulin secretion from a mouse pancreatic beta-cell line. J Endocrinol 2000;164:307-314
-
(2000)
J Endocrinol
, vol.164
, pp. 307-314
-
-
Iizuka, K.1
Nakjima, H.2
Ono, A.3
Okita, K.4
Miyazaki, J.-I.5
Miyagawa, J.-I.6
Namba, M.7
Hanafusa, T.8
Matsuzawa, Y.9
-
33
-
-
34248162028
-
Transcription factor 7-like 2 (TCF7L2) is associated with gestational diabetes mellitus and interacts with adiposity to alter insulin secretion in Mexican Americans
-
Watanabe RM, Allayee H, Xiang AH, Trigo E, Hartiala J, Lawrence JM, Buchanan TA. Transcription factor 7-like 2 (TCF7L2) is associated with gestational diabetes mellitus and interacts with adiposity to alter insulin secretion in Mexican Americans. Diabetes 2007;56:1481-1485
-
(2007)
Diabetes
, vol.56
, pp. 1481-1485
-
-
Watanabe, R.M.1
Allayee, H.2
Xiang, A.H.3
Trigo, E.4
Hartiala, J.5
Lawrence, J.M.6
Buchanan, T.A.7
-
34
-
-
42449130081
-
Evidence of interaction between peroxisome proliferator-activated receptor-γ2 and hepatocyte nuclear factor-4α contributing to variation in insulin sensitivity in Mexican Americans
-
Black MH, Fingerlin TE, Allayee H, Zhang W, Xiang AH, Trigo E, Hartiala J, Lehtinen AB, Haffner SM, Bergman RN, McEachin RC, Kjos SL, Lawrence JM, Buchanan TA, Watanabe RM. Evidence of interaction between peroxisome proliferator-activated receptor-γ2 and hepatocyte nuclear factor-4α contributing to variation in insulin sensitivity in Mexican Americans. Diabetes 2008;57:1048-1056
-
(2008)
Diabetes
, vol.57
, pp. 1048-1056
-
-
Black, M.H.1
Fingerlin, T.E.2
Allayee, H.3
Zhang, W.4
Xiang, A.H.5
Trigo, E.6
Hartiala, J.7
Lehtinen, A.B.8
Haffner, S.M.9
Bergman, R.N.10
McEachin, R.C.11
Kjos, S.L.12
Lawrence, J.M.13
Buchanan, T.A.14
Watanabe, R.M.15
-
35
-
-
63049114182
-
Variation in IGF2BP2 interacts with adiposity to alter insulin sensitivity in Mexican Americans
-
Li X, Allayee H, Xiang AH, Trigo E, Hartiala J, Lawrence JM, Buchanan TA, Watanabe RM. Variation in IGF2BP2 interacts with adiposity to alter insulin sensitivity in Mexican Americans. Obesity 2009;17:729-736
-
(2009)
Obesity
, vol.17
, pp. 729-736
-
-
Li, X.1
Allayee, H.2
Xiang, A.H.3
Trigo, E.4
Hartiala, J.5
Lawrence, J.M.6
Buchanan, T.A.7
Watanabe, R.M.8
-
36
-
-
34247855851
-
Variants of transcription factor 7-like 2 (TCF7L2) gene predict conversion to type 2 diabetes in the Finnish Diabetes Prevention Study and are associated with impaired glucose regulation and impaired insulin secretion
-
Wang J, Kuusisto J, Vänttinen M, Kuulasmaa T, Lindström J, Tuomilehto J, Uusitupa M, Laakso M. Variants of transcription factor 7-like 2 (TCF7L2) gene predict conversion to type 2 diabetes in the Finnish Diabetes Prevention Study and are associated with impaired glucose regulation and impaired insulin secretion. Diabetologia 2007;50:1192-1200
-
(2007)
Diabetologia
, vol.50
, pp. 1192-1200
-
-
Wang, J.1
Kuusisto, J.2
Vänttinen, M.3
Kuulasmaa, T.4
Lindström, J.5
Tuomilehto, J.6
Uusitupa, M.7
Laakso, M.8
-
37
-
-
0033499585
-
Antepartum predictors of the development of type 2 diabetes in Latino women 11-26 months after pregnancies complicated by gestational diabetes
-
Buchanan TA, Xiang AH, Kjos SL, Trigo E, Lee WP, Peters RK. Antepartum predictors of the development of type 2 diabetes in Latino women 11-26 months after pregnancies complicated by gestational diabetes. Diabetes 1999;48:2430-2436
-
(1999)
Diabetes
, vol.48
, pp. 2430-2436
-
-
Buchanan, T.A.1
Xiang, A.H.2
Kjos, S.L.3
Trigo, E.4
Lee, W.P.5
Peters, R.K.6
-
38
-
-
0033006003
-
Allelic discrimination using fluorogenic probes and the 5′ nuclease assay
-
Livak KJ. Allelic discrimination using fluorogenic probes and the 5′ nuclease assay. Genet Anal 1999;14:143-149
-
(1999)
Genet Anal
, vol.14
, pp. 143-149
-
-
Livak, K.J.1
-
39
-
-
0842345931
-
SNP genotyping by the 5′-nuclease reaction
-
Livak KJ. SNP genotyping by the 5′-nuclease reaction. Methods Mol Biol 2003;212:129-147
-
(2003)
Methods Mol Biol
, vol.212
, pp. 129-147
-
-
Livak, K.J.1
-
40
-
-
79959524146
-
A haplotype map of the human genome
-
The International HapMap Consortium
-
The International HapMap Consortium. A haplotype map of the human genome. Nature 2005;437:1299-1320
-
(2005)
Nature
, vol.437
, pp. 1299-1320
-
-
-
41
-
-
32044441883
-
Tag SNP selection for Finnish individuals based on the CEPH Utah HapMap database
-
Willer CJ, Scott LJ, Bonnycastle LL, Jackson AU, Chines P, Pruim R, Bark CW, Tsai Y, Pugh EW, Doheny KF, Kinnumem L, Mohlke KL, Valle TT, Bergman RN, Tuomilehto J, Collins FS, Boehnke M. Tag SNP selection for Finnish individuals based on the CEPH Utah HapMap database. Genet Epidemiol 2006;30:180-190
-
(2006)
Genet Epidemiol
, vol.30
, pp. 180-190
-
-
Willer, C.J.1
Scott, L.J.2
Bonnycastle, L.L.3
Jackson, A.U.4
Chines, P.5
Pruim, R.6
Bark, C.W.7
Tsai, Y.8
Pugh, E.W.9
Doheny, K.F.10
Kinnumem, L.11
Mohlke, K.L.12
Valle, T.T.13
Bergman, R.N.14
Tuomilehto, J.15
Collins, F.S.16
Boehnke, M.17
-
42
-
-
24044550689
-
PEDSTATS: Descriptive statistics, graphics and quality assessment for gene mapping data
-
Wigginton JE, Abecasis GR. PEDSTATS: descriptive statistics, graphics and quality assessment for gene mapping data. Bioinformatics 2005;21:3445-3447
-
(2005)
Bioinformatics
, vol.21
, pp. 3445-3447
-
-
Wigginton, J.E.1
Abecasis, G.R.2
-
43
-
-
0031442937
-
Multipoint oligogenic linkage analysis of quantitative traits
-
Blangero J, Almasy L. Multipoint oligogenic linkage analysis of quantitative traits. Genet Epidemiol 1997;14:959-964
-
(1997)
Genet Epidemiol
, vol.14
, pp. 959-964
-
-
Blangero, J.1
Almasy, L.2
-
44
-
-
0031966959
-
Multipoint quantitative-trait linkage analysis in general pedigrees
-
Almasy L, Blangero J. Multipoint quantitative-trait linkage analysis in general pedigrees. Am J Hum Genet 1998;62:1198-1211
-
(1998)
Am J Hum Genet
, vol.62
, pp. 1198-1211
-
-
Almasy, L.1
Blangero, J.2
-
45
-
-
0347624611
-
MINMOD Millennium: A computer program to calculate glucose effectiveness and insulin sensitivity from the frequently sampled intravenous glucose tolerance test
-
Boston RC, Stefanovski D, Moate PJ, Sumner AE, Watanabe RM, Bergman RN. MINMOD Millennium: a computer program to calculate glucose effectiveness and insulin sensitivity from the frequently sampled intravenous glucose tolerance test. Diab Tech Therap 2003;5:1003-1015
-
(2003)
Diab Tech Therap
, vol.5
, pp. 1003-1015
-
-
Boston, R.C.1
Stefanovski, D.2
Moate, P.J.3
Sumner, A.E.4
Watanabe, R.M.5
Bergman, R.N.6
-
46
-
-
36749079336
-
So many correlated tests, so little time! Rapid adjustment of P values for multiple correlated tests
-
Conneely KN, Boehnke M. So many correlated tests, so little time! Rapid adjustment of P values for multiple correlated tests. Am J Hum Genet 2007;81:1158-1168
-
(2007)
Am J Hum Genet
, vol.81
, pp. 1158-1168
-
-
Conneely, K.N.1
Boehnke, M.2
-
47
-
-
73249124453
-
Roles of islet glucose 6 phosphatase related protein in islet function in vivo and in vitro
-
Pirot PG, Hackl SI, O'Brien RM, Davidson HW, Hutton JC. Roles of islet glucose 6 phosphatase related protein in islet function in vivo and in vitro. Diabetologia 2008;51:S200
-
(2008)
Diabetologia
, vol.51
-
-
Pirot, P.G.1
Hackl, S.I.2
O'Brien, R.M.3
Davidson, H.W.4
Hutton, J.C.5
-
48
-
-
33749324476
-
Mechanisms of impaired fasting glucose and glucose intolerance induced by an approximate 50% pancreatectomy
-
Matveyenko AV, Veldhuis JD, Butler PC. Mechanisms of impaired fasting glucose and glucose intolerance induced by an approximate 50% pancreatectomy. Diabetes 2006;55:2347-2356
-
(2006)
Diabetes
, vol.55
, pp. 2347-2356
-
-
Matveyenko, A.V.1
Veldhuis, J.D.2
Butler, P.C.3
-
49
-
-
33747055111
-
β-cell deficit due to increased apoptosis in the human islet amyloid polypeptide transgenic (HIP) rat recapitulates the metabolic defects present in type 2 diabetes
-
Matveyenko AV, Butler PC. β-cell deficit due to increased apoptosis in the human islet amyloid polypeptide transgenic (HIP) rat recapitulates the metabolic defects present in type 2 diabetes. Diabetes 2006;55:2106-2114
-
(2006)
Diabetes
, vol.55
, pp. 2106-2114
-
-
Matveyenko, A.V.1
Butler, P.C.2
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