Variants of transcription factor 7-like 2 (TCF7L2) gene predict conversion to type 2 diabetes in the Finnish Diabetes Prevention Study and are associated with impaired glucose regulation and impaired insulin secretion

Diabetologia

Volumn 50, Issue 6, 2007, Pages 1192-1200

  Wang, J ^a   Kuusisto, J ^a   Vanttinen M ^a   Kuulasmaa, T ^a   Lindstrom J ^b   Tuomilehto, J ^b,c,d   Uusitupa, M ^a   Laakso, M ^a  

^a KUOPIO UNIVERSITY HOSPITAL   (Finland)

^b NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^c UNIVERSITY OF HELSINKI   (Finland)

^d SOUTH OSTROBOTHNIA CENTRAL HOSPITAL   (Finland)

Author keywords

Genotyping; Impaired fasting glucose; Impaired glucose tolerance; Incidence; Insulin secretion; Insulin sensitivity; Lifestyle intervention; TCF7L2; Type 2 diabetes; Variants

Indexed keywords

GLUCOSE; INSULIN; TRANSCRIPTION FACTOR 7; TRANSCRIPTION FACTOR 7 LIKE 2; UNCLASSIFIED DRUG;

ADIPOSE TISSUE; ADULT; ARTICLE; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DIABETES CONTROL; FEMALE; FINLAND; GENETIC ASSOCIATION; GENETIC RISK; GENETIC VARIABILITY; GENOTYPE; GLUCOSE BLOOD LEVEL; HUMAN; IMPAIRED GLUCOSE TOLERANCE; INSULIN RELEASE; INSULIN SENSITIVITY; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; ORAL GLUCOSE TOLERANCE TEST; POPULATION RESEARCH; PRIORITY JOURNAL; PROGENY; PROTEIN EXPRESSION;

CROSS-SECTIONAL STUDIES; DIABETES MELLITUS, TYPE 2; FEMALE; FINLAND; GLUCOSE INTOLERANCE; GLUCOSE TOLERANCE TEST; HUMANS; INCIDENCE; INSULIN; MALE; NUCLEAR FAMILY; TCF TRANSCRIPTION FACTORS; VARIATION (GENETICS);

EID: 34247855851     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00125-007-0656-6     Document Type: Article

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