The flavoheme reductase Ncb5or protects cells against endoplasmic reticulum stress-induced lipotoxicity

Journal of Lipid Research

Volumn 51, Issue 1, 2010, Pages 53-62

  Zhang, Yongzhao ^a   Larade, Kevin ^a   Jiang, Zhi Gang ^a   Ito, Susumu ^b   Wang, WenFang ^c   Zhu, Hao ^c   Bunn, H Franklin ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF KANSAS MEDICAL CENTER   (United States)

Author keywords

Diabetes; Endoplasmic reticulum; Hyperglycemia; Lipoatrophy; Lipotoxicity; Reductase

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 3; ACTIVATING TRANSCRIPTION FACTOR 6; CCAAT ENHANCER BINDING PROTEIN; FATTY ACID; GLUCOSE REGULATED PROTEIN 78; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; MESSENGER RNA; OLEIC ACID; PALMITIC ACID; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR NCB5OR; TUNICAMYCIN; UNCLASSIFIED DRUG; X BOX BINDING PROTEIN 1;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DIABETES MELLITUS; ENDOPLASMIC RETICULUM STRESS; GENE DISRUPTION; HYPERGLYCEMIA; IN VIVO STUDY; LIPOTOXICITY; LIVER CELL; MOUSE; NICK END LABELING; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SENSITIVITY ANALYSIS; TOXICITY; TRANSMISSION ELECTRON MICROSCOPY;

ANIMALS; ANTI-BACTERIAL AGENTS; APOPTOSIS; BIOLOGICAL MARKERS; BLOOD GLUCOSE; CELL SURVIVAL; CYTOCHROME-B(5) REDUCTASE; DIABETES MELLITUS; ENDOPLASMIC RETICULUM; HEPATOCYTES; HYPERGLYCEMIA; INSULIN; MICE; MICE, KNOCKOUT; MICROSCOPY, ELECTRON, TRANSMISSION; OLEIC ACID; PALMITATES; PANCREAS; STRESS, PHYSIOLOGICAL; TRANSCRIPTION FACTOR CHOP; TUNICAMYCIN;

EID: 73149091849     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M900146-JLR200     Document Type: Article

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