-
1
-
-
33846911453
-
Suppression of beta-amyloid precursor protein signaling into the nucleus by estrogens mediated through complex formation between the estrogen receptor and Fe65
-
Bao J., Cao C., Zhang X., Jiang F., Nicosia S. V. Bai W. (2007) Suppression of beta-amyloid precursor protein signaling into the nucleus by estrogens mediated through complex formation between the estrogen receptor and Fe65. Mol. Cell. Biol. 27, 1321 1333.
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 1321-1333
-
-
Bao, J.1
Cao, C.2
Zhang, X.3
Jiang, F.4
Nicosia, S.V.5
Bai, W.6
-
2
-
-
0035816661
-
A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60
-
Cao X. Sudhof T. C. (2001) A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60. Science 293, 115 120.
-
(2001)
Science
, vol.293
, pp. 115-120
-
-
Cao, X.1
Sudhof, T.C.2
-
3
-
-
2642582435
-
Dissection of amyloid-beta precursor protein-dependent transcriptional transactivation
-
Cao X. Sudhof T. C. (2004) Dissection of amyloid-beta precursor protein-dependent transcriptional transactivation. J. Biol. Chem. 279, 24601 24611.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 24601-24611
-
-
Cao, X.1
Sudhof, T.C.2
-
4
-
-
0031451149
-
The WW domain of neural protein FE65 interacts with proline-rich motifs in Mena, the mammalian homolog of Drosophila enabled
-
Ermekova K. S., Zambrano N., Linn H., Minopoli G., Gertler F., Russo T. Sudol M. (1997) The WW domain of neural protein FE65 interacts with proline-rich motifs in Mena, the mammalian homolog of Drosophila enabled. J. Biol. Chem. 272, 32869 32877.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 32869-32877
-
-
Ermekova, K.S.1
Zambrano, N.2
Linn, H.3
Minopoli, G.4
Gertler, F.5
Russo, T.6
Sudol, M.7
-
5
-
-
33646480747
-
Reversal of Alzheimer's-like pathology and behavior in human APP transgenic mice by mutation of Asp664
-
Galvan V., Gorostiza O. F., Banwait S. et al. (2006) Reversal of Alzheimer's-like pathology and behavior in human APP transgenic mice by mutation of Asp664. Proc. Natl. Acad. Sci. USA 103, 7130 7135.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 7130-7135
-
-
Galvan, V.1
Gorostiza, O.F.2
Banwait, S.3
-
6
-
-
31444442064
-
Essential roles for the FE65 amyloid precursor protein-interacting proteins in brain development
-
Guenette S., Chang Y., Hiesberger T., Richardson J. A., Eckman C. B., Eckman E. A., Hammer R. E. Herz J. (2006) Essential roles for the FE65 amyloid precursor protein-interacting proteins in brain development. EMBO J. 25, 420 431.
-
(2006)
EMBO J.
, vol.25
, pp. 420-431
-
-
Guenette, S.1
Chang, Y.2
Hiesberger, T.3
Richardson, J.A.4
Eckman, C.B.5
Eckman, E.A.6
Hammer, R.E.7
Herz, J.8
-
7
-
-
0031052381
-
Amyloid, the presenilins and Alzheimer's disease
-
Hardy J. (1997) Amyloid, the presenilins and Alzheimer's disease. Trends Neurosci. 20, 154 159.
-
(1997)
Trends Neurosci.
, vol.20
, pp. 154-159
-
-
Hardy, J.1
-
8
-
-
27744587358
-
A gamma-secretase-independent mechanism of signal transduction by the amyloid precursor protein
-
Hass M. R. Yankner B. A. (2005) A gamma-secretase-independent mechanism of signal transduction by the amyloid precursor protein. J. Biol. Chem. 280, 36895 36904.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 36895-36904
-
-
Hass, M.R.1
Yankner, B.A.2
-
9
-
-
33745584643
-
Regulated intramembrane proteolysis of amyloid precursor protein and regulation of expression of putative target genes
-
Hebert S. S., Serneels L., Tolia A., Craessaerts K., Derks C., Filippov M. A., Muller U. De Strooper B. (2006) Regulated intramembrane proteolysis of amyloid precursor protein and regulation of expression of putative target genes. EMBO Rep. 7, 739 745.
-
(2006)
EMBO Rep.
, vol.7
, pp. 739-745
-
-
Hebert, S.S.1
Serneels, L.2
Tolia, A.3
Craessaerts, K.4
Derks, C.5
Filippov, M.A.6
Muller, U.7
De Strooper, B.8
-
10
-
-
0031710443
-
The human FE65 gene: Genomic structure and an intronic biallelic polymorphism associated with sporadic dementia of the Alzheimer type
-
Hu Q., Kukull W. A., Bressler S. L., Gray M. D., Cam J. A., Larson E. B., Martin G. M. Deeb S. S. (1998) The human FE65 gene: genomic structure and an intronic biallelic polymorphism associated with sporadic dementia of the Alzheimer type. Hum. Genet. 103, 295 303.
-
(1998)
Hum. Genet.
, vol.103
, pp. 295-303
-
-
Hu, Q.1
Kukull, W.A.2
Bressler, S.L.3
Gray, M.D.4
Cam, J.A.5
Larson, E.B.6
Martin, G.M.7
Deeb, S.S.8
-
11
-
-
0033485891
-
Alternatively spliced isoforms of FE65 serve as neuron-specific and non-neuronal markers
-
Hu Q., Hearn M. G., Jin L. W., Bressler S. L. Martin G. M. (1999) Alternatively spliced isoforms of FE65 serve as neuron-specific and non-neuronal markers. J. Neurosci. Res. 58, 632 640.
-
(1999)
J. Neurosci. Res.
, vol.58
, pp. 632-640
-
-
Hu, Q.1
Hearn, M.G.2
Jin, L.W.3
Bressler, S.L.4
Martin, G.M.5
-
12
-
-
0037084853
-
A candidate molecular mechanism for the association of an intronic polymorphism of FE65 with resistance to very late onset dementia of the Alzheimer type
-
Hu Q., Cool B. H., Wang B., Hearn M. G. Martin G. M. (2002) A candidate molecular mechanism for the association of an intronic polymorphism of FE65 with resistance to very late onset dementia of the Alzheimer type. Hum. Mol. Genet. 11, 465 475.
-
(2002)
Hum. Mol. Genet.
, vol.11
, pp. 465-475
-
-
Hu, Q.1
Cool, B.H.2
Wang, B.3
Hearn, M.G.4
Martin, G.M.5
-
13
-
-
16844374267
-
Endoproteolytic cleavage of FE65 converts the adaptor protein to a potent suppressor of the sAPPalpha pathway in primates
-
Hu Q., Wang L., Yang Z., Cool B. H., Zitnik G. Martin G. M. (2005) Endoproteolytic cleavage of FE65 converts the adaptor protein to a potent suppressor of the sAPPalpha pathway in primates. J. Biol. Chem. 280, 12548 12558.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 12548-12558
-
-
Hu, Q.1
Wang, L.2
Yang, Z.3
Cool, B.H.4
Zitnik, G.5
Martin, G.M.6
-
14
-
-
34247349579
-
A macromolecular complex involving the amyloid precursor protein (APP) and the cytosolic adapter FE65 is a negative regulator of axon branching
-
Ikin A. F., Sabo S. L., Lanier L. M. Buxbaum J. D. (2007) A macromolecular complex involving the amyloid precursor protein (APP) and the cytosolic adapter FE65 is a negative regulator of axon branching. Mol. Cell. Neurosci. 35, 57 63.
-
(2007)
Mol. Cell. Neurosci.
, vol.35
, pp. 57-63
-
-
Ikin, A.F.1
Sabo, S.L.2
Lanier, L.M.3
Buxbaum, J.D.4
-
15
-
-
0037049236
-
Expression of the Fe65 adapter protein in adult and developing mouse brain
-
Kesavapany S., Banner S. J., Lau K. F., Shaw C. E., Miller C. C., Cooper J. D. McLoughlin D. M. (2002) Expression of the Fe65 adapter protein in adult and developing mouse brain. Neuroscience 115, 951 960.
-
(2002)
Neuroscience
, vol.115
, pp. 951-960
-
-
Kesavapany, S.1
Banner, S.J.2
Lau, K.F.3
Shaw, C.E.4
Miller, C.C.5
Cooper, J.D.6
McLoughlin, D.M.7
-
16
-
-
34249662300
-
Notch1 intracellular domain suppresses APP intracellular domain-Tip60-Fe65 complex mediated signaling through physical interaction
-
Kim S. Y., Kim M. Y., Mo J. S. Park H. S. (2007) Notch1 intracellular domain suppresses APP intracellular domain-Tip60-Fe65 complex mediated signaling through physical interaction. Biochim. Biophys. Acta 1773, 736 746.
-
(2007)
Biochim. Biophys. Acta
, vol.1773
, pp. 736-746
-
-
Kim, S.Y.1
Kim, M.Y.2
Mo, J.S.3
Park, H.S.4
-
17
-
-
0034693448
-
A FE65 polymorphism associated with risk of developing sporadic late-onset alzheimer's disease but not with Abeta loading in brains
-
Lambert J. C., Mann D., Goumidi L. et al. (2000) A FE65 polymorphism associated with risk of developing sporadic late-onset alzheimer's disease but not with Abeta loading in brains. Neurosci. Lett. 293, 29 32.
-
(2000)
Neurosci. Lett.
, vol.293
, pp. 29-32
-
-
Lambert, J.C.1
Mann, D.2
Goumidi, L.3
-
18
-
-
34548499548
-
Structural basis for polyproline recognition by the FE65 WW domain
-
Meiyappan M., Birrane G. Ladias J. A. (2007) Structural basis for polyproline recognition by the FE65 WW domain. J. Mol. Biol. 372, 970 980.
-
(2007)
J. Mol. Biol.
, vol.372
, pp. 970-980
-
-
Meiyappan, M.1
Birrane, G.2
Ladias, J.A.3
-
19
-
-
0035794182
-
The β-Amyloid Precursor Protein Functions as a Cytosolic Anchoring Site That Prevents Fe65 Nuclear Translocation
-
DOI 10.1074/jbc.M007340200
-
Minopoli G., de Candia P., Bonetti A., Faraonio R., Zambrano N. Russo T. (2001) The beta-amyloid precursor protein functions as a cytosolic anchoring site that prevents Fe65 nuclear translocation. J. Biol. Chem. 276, 6545 6550. (Pubitemid 37373518)
-
(2001)
Journal of Biological Chemistry
, vol.276
, Issue.9
, pp. 6545-6550
-
-
Minopoli, G.1
De Candia, P.2
Bonetti, A.3
Faraonio, R.4
Zambrano, N.5
Russo, T.6
-
20
-
-
2542423595
-
The c-Abl tyrosine kinase phosphorylates the Fe65 adaptor protein to stimulate Fe65amyloid precursor protein nuclear signaling
-
Perkinton M. S., Standen C. L., Lau K. F., Kesavapany S., Byers H. L., Ward M., McLoughlin D. M. Miller C. C. (2004) The c-Abl tyrosine kinase phosphorylates the Fe65 adaptor protein to stimulate Fe65amyloid precursor protein nuclear signaling. J. Biol. Chem. 279, 22084 22091.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 22084-22091
-
-
Perkinton, M.S.1
Standen, C.L.2
Lau, K.F.3
Kesavapany, S.4
Byers, H.L.5
Ward, M.6
McLoughlin, D.M.7
Miller, C.C.8
-
21
-
-
2442498577
-
FE65 constitutes the functional link between the low-density lipoprotein receptor-related protein and the amyloid precursor protein
-
Pietrzik C. U., Yoon I. S., Jaeger S., Busse T., Weggen S. Koo E. H. (2004) FE65 constitutes the functional link between the low-density lipoprotein receptor-related protein and the amyloid precursor protein. J. Neurosci. 24, 4259 4265.
-
(2004)
J. Neurosci.
, vol.24
, pp. 4259-4265
-
-
Pietrzik, C.U.1
Yoon, I.S.2
Jaeger, S.3
Busse, T.4
Weggen, S.5
Koo, E.H.6
-
22
-
-
0031921466
-
Mutant genes in familial Alzheimer's disease and transgenic models
-
Price D. L. Sisodia S. S. (1998) Mutant genes in familial Alzheimer's disease and transgenic models. Annu. Rev. Neurosci. 21, 479 505.
-
(1998)
Annu. Rev. Neurosci.
, vol.21
, pp. 479-505
-
-
Price, D.L.1
Sisodia, S.S.2
-
23
-
-
0033583316
-
Regulation of beta-amyloid secretion by FE65, an amyloid protein precursor-binding protein
-
Sabo S. L., Lanier L. M., Ikin A. F., Khorkova O., Sahasrabudhe S., Greengard P. Buxbaum J. D. (1999) Regulation of beta-amyloid secretion by FE65, an amyloid protein precursor-binding protein. J. Biol. Chem. 274, 7952 7957.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 7952-7957
-
-
Sabo, S.L.1
Lanier, L.M.2
Ikin, A.F.3
Khorkova, O.4
Sahasrabudhe, S.5
Greengard, P.6
Buxbaum, J.D.7
-
24
-
-
0035954426
-
The Alzheimer amyloid precursor protein (APP) and FE65, an APP-binding protein, regulate cell movement
-
Sabo S. L., Ikin A. F., Buxbaum J. D. Greengard P. (2001) The Alzheimer amyloid precursor protein (APP) and FE65, an APP-binding protein, regulate cell movement. J. Cell Biol. 153, 1403 1414.
-
(2001)
J. Cell Biol.
, vol.153
, pp. 1403-1414
-
-
Sabo, S.L.1
Ikin, A.F.2
Buxbaum, J.D.3
Greengard, P.4
-
25
-
-
0038722283
-
The amyloid precursor protein and its regulatory protein, FE65, in growth cones and synapses in vitro and in vivo
-
Sabo S. L., Ikin A. F., Buxbaum J. D. Greengard P. (2003) The amyloid precursor protein and its regulatory protein, FE65, in growth cones and synapses in vitro and in vivo. J. Neurosci. 23, 5407 5415.
-
(2003)
J. Neurosci.
, vol.23
, pp. 5407-5415
-
-
Sabo, S.L.1
Ikin, A.F.2
Buxbaum, J.D.3
Greengard, P.4
-
26
-
-
33845898816
-
Deficits in synaptic transmission and learning in amyloid precursor protein (APP) transgenic mice require C-terminal cleavage of APP
-
Saganich M. J., Schroeder B. E., Galvan V., Bredesen D. E., Koo E. H. Heinemann S. F. (2006) Deficits in synaptic transmission and learning in amyloid precursor protein (APP) transgenic mice require C-terminal cleavage of APP. J. Neurosci. 26, 13428 13436.
-
(2006)
J. Neurosci.
, vol.26
, pp. 13428-13436
-
-
Saganich, M.J.1
Schroeder, B.E.2
Galvan, V.3
Bredesen, D.E.4
Koo, E.H.5
Heinemann, S.F.6
-
27
-
-
0032574993
-
Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain
-
Schroeter E. H., Kisslinger J. A. Kopan R. (1998) Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain. Nature 393, 382 386.
-
(1998)
Nature
, vol.393
, pp. 382-386
-
-
Schroeter, E.H.1
Kisslinger, J.A.2
Kopan, R.3
-
28
-
-
0032524325
-
Nuclear access and action of notch in vivo
-
Struhl G. Adachi A. (1998) Nuclear access and action of notch in vivo. Cell 93, 649 660.
-
(1998)
Cell
, vol.93
, pp. 649-660
-
-
Struhl, G.1
Adachi, A.2
-
29
-
-
21444436589
-
Transcription regulation by the adaptor protein Fe65 and the nucleosome assembly factor SET
-
Telese F., Bruni P., Donizetti A., Gianni D., D'Ambrosio C., Scaloni A., Zambrano N., Rosenfeld M. G. Russo T. (2005) Transcription regulation by the adaptor protein Fe65 and the nucleosome assembly factor SET. EMBO Rep. 6, 77 82.
-
(2005)
EMBO Rep.
, vol.6
, pp. 77-82
-
-
Telese, F.1
Bruni, P.2
Donizetti, A.3
Gianni, D.4
D'Ambrosio, C.5
Scaloni, A.6
Zambrano, N.7
Rosenfeld, M.G.8
Russo, T.9
-
30
-
-
0032509346
-
Interaction of cytosolic adaptor proteins with neuronal apolipoprotein e receptors and the amyloid precursor protein
-
Trommsdorff M., Borg J. P., Margolis B. Herz J. (1998) Interaction of cytosolic adaptor proteins with neuronal apolipoprotein E receptors and the amyloid precursor protein. J. Biol. Chem. 273, 33556 33560.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 33556-33560
-
-
Trommsdorff, M.1
Borg, J.P.2
Margolis, B.3
Herz, J.4
-
31
-
-
0042634362
-
Roles of amyloid precursor protein and its fragments in regulating neural activity, plasticity and memory
-
Turner P. R., O'Connor K., Tate W. P. Abraham W. C. (2003) Roles of amyloid precursor protein and its fragments in regulating neural activity, plasticity and memory. Prog. Neurobiol. 70, 1 32.
-
(2003)
Prog. Neurobiol.
, vol.70
, pp. 1-32
-
-
Turner, P.R.1
O'Connor, K.2
Tate, W.P.3
Abraham, W.C.4
-
32
-
-
9144262348
-
Isoform-specific knockout of FE65 leads to impaired learning and memory
-
Wang B., Hu Q., Hearn M. G., Shimizu K., Ware C. B., Liggitt D. H., Jin L. W., Cool B. H., Storm D. R. Martin G. M. (2004) Isoform-specific knockout of FE65 leads to impaired learning and memory. J. Neurosci. Res. 75, 12 24.
-
(2004)
J. Neurosci. Res.
, vol.75
, pp. 12-24
-
-
Wang, B.1
Hu, Q.2
Hearn, M.G.3
Shimizu, K.4
Ware, C.B.5
Liggitt, D.H.6
Jin, L.W.7
Cool, B.H.8
Storm, D.R.9
Martin, G.M.10
-
33
-
-
33645218231
-
A dominant role for FE65 (APBB1) in nuclear signaling
-
Yang Z., Cool B. H., Martin G. M. Hu Q. (2006) A dominant role for FE65 (APBB1) in nuclear signaling. J. Biol. Chem. 281, 4207 4214.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 4207-4214
-
-
Yang, Z.1
Cool, B.H.2
Martin, G.M.3
Hu, Q.4
-
34
-
-
0032493814
-
The Fe65 adaptor protein interacts through its PID1 domain with the transcription factor CP2LSFLBP1
-
Zambrano N., Minopoli G., de Candia P. Russo T. (1998) The Fe65 adaptor protein interacts through its PID1 domain with the transcription factor CP2LSFLBP1. J. Biol. Chem. 273, 20128 20133.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 20128-20133
-
-
Zambrano, N.1
Minopoli, G.2
De Candia, P.3
Russo, T.4
-
35
-
-
0035827587
-
The beta-amyloid precursor protein APP is tyrosine-phosphorylated in cells expressing a constitutively active form of the Abl protoncogene
-
Zambrano N., Bruni P., Minopoli G., Mosca R., Molino D., Russo C., Schettini G., Sudol M. Russo T. (2001) The beta-amyloid precursor protein APP is tyrosine-phosphorylated in cells expressing a constitutively active form of the Abl protoncogene. J. Biol. Chem. 276, 19787 19792.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 19787-19792
-
-
Zambrano, N.1
Bruni, P.2
Minopoli, G.3
Mosca, R.4
Molino, D.5
Russo, C.6
Schettini, G.7
Sudol, M.8
Russo, T.9
|