Oxidation of potassium channels by ROS: a general mechanism of aging and neurodegeneration?

Trends in Cell Biology

Volumn 20, Issue 1, 2010, Pages 45-51

  Sesti, Federico ^a   Liu, Shuang ^a   Cai, Shi Qing ^a  

^a RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM); CHARYBDOTOXIN; HYDROGEN PEROXIDE; LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; PAXILLINE; POTASSIUM CHANNEL; POTASSIUM CHANNEL KVS 1; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

AFTERHYPERPOLARIZATION; AGING; ALZHEIMER DISEASE; BRAIN; DISEASE COURSE; DOPAMINERGIC NERVE CELL; ENZYME ACTIVITY; HIPPOCAMPUS; HUMAN; NERVE CELL; NERVE CELL EXCITABILITY; NERVE DEGENERATION; NEUROPATHOLOGY; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVIEW;

AGING; ANIMALS; HUMANS; NERVE DEGENERATION; OXIDATION-REDUCTION; POTASSIUM CHANNELS; REACTIVE OXYGEN SPECIES;

CAENORHABDITIS ELEGANS; MAMMALIA;

EID: 72549084916     PISSN: 09628924     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tcb.2009.09.008     Document Type: Review

References (86)

1. Harman D. The biologic clock: the mitochondria?. J. Am. Geriatr. Soc. 20 (1972) 145-147
2. Lin M.T., and Beal M.F. Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases. Nature 443 (2006) 787-795
3. Matalon S., et al. Regulation of ion channel structure and function by reactive oxygen-nitrogen species. Am. J. Physiol. Lung Cell Mol. Physiol. 285 (2003) L1184-L1189
4. Cai S.-Q., and Sesti F. Oxidation of a potassium channel causes progressive sensory function loss during aging. Nat. Neurosci. 12 (2009) 611-617
5. Bianchi L., et al. A potassium channel-MiRP complex controls neurosensory function in Caenorhabditis elegans. J. Biol. Chem. 278 (2003) 12415-12424
6. Bargmann C., and Mori I. Chemotaxis and thermotaxis. In: Riddle D.L., et al. (Ed). C. elegans II Vol. 1 (1997), Cold Spring Harbor Laboratory Press 717-737
7. Annunziato L., et al. Modulation of ion channels by reactive oxygen and nitrogen species: a pathophysiological role in brain aging?. Neurobiol. Aging 23 (2002) 819-834
8. O'Keefe J., and Dostrovsky J. The hippocampus as a spatial map. Preliminary evidence from unit activity in the freely-moving rat. Brain Res. 34 (1971) 171-175
9. Moser E.I., et al. Place cells, grid cells, and the brain's spatial representation system. Annu. Rev. Neurosci. 31 (2008) 69-89
10. Storm J.F. Action potential repolarization and a fast after-hyperpolarization in rat hippocampal pyramidal cells. J. Physiol. 385 (1987) 733-759
11. Moyer Jr. J.R., et al. Trace eyeblink conditioning increases CA1 excitability in a transient and learning-specific manner. J. Neurosci. 16 (1996) 5536-5546
12. Power J.M., et al. Age-related enhancement of the slow outward calcium-activated potassium current in hippocampal CA1 pyramidal neurons in vitro. J. Neurosci. 22 (2002) 7234-7243
13. + channel knock-out mice reveal the identity of calcium-dependent afterhyperpolarization currents. J. Neurosci. 24 (2004) 5301-5306
14. + current in hippocampal pyramidal neurons. Proc. Natl. Acad. Sci. U.S.A. 96 (1999) 4662-4667
15. + channel SK3 generates age-related memory and LTP deficits. Nat. Neurosci. 6 (2003) 911-912
16. Serrano F., and Klann E. Reactive oxygen species and synaptic plasticity in the aging hippocampus. Ageing Res. Rev. 3 (2004) 431-443
17. Hu D., et al. Aging-dependent alterations in synaptic plasticity and memory in mice that overexpress extracellular superoxide dismutase. J. Neurosci. 26 (2006) 3933-3941
18. + channels in glutamatergic hippocampal terminals and their role in spike repolarization and regulation of transmitter release. J. Neurosci. 21 (2001) 9585-9597
19. + channels of the BK-type in the mouse brain. Histochem. Cell Biol. 125 (2006) 725-741
20. + channels and modulates action potentials in rat hippocampal neurons. Neurosci. Lett. 319 (2002) 79-82
21. Sailer C.A., et al. Immunolocalization of BK channels in hippocampal pyramidal neurons. Eur. J. Neurosci. 24 (2006) 442-454
22. Gu N., et al. BK potassium channels facilitate high-frequency firing and cause early spike frequency adaptation in rat CA1 hippocampal pyramidal cells. J. Physiol. 580 (2007) 859-882
23. Matthews E.A., et al. The BK-mediated fAHP is modulated by learning a hippocampus-dependent task. Proc. Natl. Acad. Sci. U. S. A. 105 (2008) 15154-15159
24. Zeng X.H., et al. Redox-sensitive extracellular gates formed by auxiliary beta subunits of calcium-activated potassium channels. Nat. Struct. Biol. 10 (2003) 448-454
25. + channels. J. Physiol. 571 (2006) 329-348
26. Tang X.D., et al. Reactive oxygen species impair Slo1 BK channel function by altering cysteine-mediated calcium sensing. Nat. Struct. Mol. Biol. 1 (2004) 171-178
27. + channels. Biochem. Biophys. Res. Commun. 342 (2006) 1389-1395
28. Gong L., et al. Redox modulation of large conductance calcium-activated potassium channels in CA1 pyramidal neurons from adult rat hippocampus. Neurosci. Lett. 286 (2000) 191-194
29. + channel inactivation, spike broadening, and after-hyperpolarization in Kvbeta1.1-deficient mice with impaired learning. Learn. Mem. 5 (1998) 257-273
30. + channel alpha and beta subunits in rat hippocampal formation. J. Neurosci. 21 (2001) 5973-5983
31. + channel mRNAs in the rat brain and down-regulation in the hippocampus following seizures. Neuron 8 (1992) 1055-1067
32. + channel polypeptides in rat hippocampal neurons developing in situ and in vitro. J. Neurosci. 15 (1995) 3840-3851
33. + current in rat hippocampal neurons. J. Neurosci. 19 (1999) 1728-1735
34. + channels in the rat central nervous system. J. Neurosci. 14 (1994) 949-972
35. Perney T.M., et al. Expression of the mRNAs for the Kv3.1 potassium channel gene in the adult and developing rat brain. J. Neurophysiol. 68 (1992) 756-766
36. Cai S.Q., et al. Multiple modes of a-type potassium current regulation. Curr. Pharm. Des. 1 (2007) 3178-3184
37. + channel beta subunits: expression and distribution of Kv beta 1 and Kv beta 2 in adult rat brain. J. Neurosci. 16 (1996) 4846-4860
38. + channels altered by presence of beta-subunit. Nature 369 (1994) 289-294
39. Falk T., et al. Developmental regulation of the A-type potassium-channel current in hippocampal neurons: role of the Kvbeta 1.1 subunit. Neuroscience 120 (2003) 387-404
40. Murphy G.G., et al. Increased neuronal excitability, synaptic plasticity, and learning in aged Kvbeta1.1 knockout mice. Curr. Biol. 14 (2004) 1907-1915
41. Ruppersberg J.P., et al. Regulation of fast inactivation of cloned mammalian IK(A) channels by cysteine oxidation. Nature 352 (1991) 711-714
42. + channels to reactive oxygen species. Proc. Natl. Acad. Sci. U. S. A. 92 (1995) 11796-11800
43. Pan Y., et al. Functional coupling between the Kv1.1 channel and aldoketoreductase Kvbeta1. J. Biol. Chem. 283 (2008) 8634-8642
44. Pal S., et al. Mediation of neuronal apoptosis by Kv2.1-encoded potassium channels. J. Neurosci. 23 (2003) 4798-4802
45. + channels depresses basal synaptic transmission in the hippocampal CA1 area in APP (swe/ind) TgCRND8 mice. Neurobiol. Aging (doi:10.1016/j.neurobiolaging.2008.05.012) (in press)
46. Coles B., et al. Potassium channels in hippocampal neurones are absent in a transgenic but not in a chemical model of Alzheimer's disease. Brain Res. 1190 (2008) 1-14
47. + channels. Science 264 (1994) 276-279
48. Etcheberrigaray R., et al. Potassium channel dysfunction in fibroblasts identifies patients with Alzheimer disease. Proc. Natl. Acad. Sci. U. S. A. 90 (1993) 8209-8213
49. de Silva H.A., et al. Abnormal function of potassium channels in platelets of patients with Alzheimer's disease. Lancet 352 (1998) 1590-1593
50. Crouch P.J., et al. Copper-dependent inhibition of cytochrome c oxidase by Abeta(1-42) requires reduced methionine at residue 35 of the Abeta peptide. J. Neurochem. 99 (2006) 226-236
51. Manczak M., et al. Mitochondria are a direct site of A beta accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression. Hum. Mol. Genet. 15 (2006) 1437-1449
52. + channels and suppression of neuronal activity by secreted beta-amyloid-precursor protein. Nature 379 (1996) 74-78
53. + channels in rat microglia. Neurosci. Lett. 300 (2001) 67-70
54. + current. Neurobiol Aging. 27 (2006) 1673-1683
55. Pannaccione A., et al. Up-regulation and increased activity of KV3.4 channels and their accessory subunit MinK-related peptide 2 induced by amyloid peptide are involved in apoptotic neuronal death. Mol. Pharmacol. 72 (2007) 665-673
56. + current in rat hippocampal neurons. Biophys. J. 70 (1996) 296-304
57. Abbott G.W., et al. Conformational changes in a mammalian voltage-dependent potassium channel inactivation peptide. Biochemistry 37 (1998) 1640-1645
58. 2. J. Neurosci. 23 (2003) 2744-2750
59. 2 underlies glutamate-dependent inhibition of striatal dopamine release. Proc. Natl. Acad. Sci. U. S. A. 100 (2003) 11729-11734
60. Liss B., et al. K-ATP channels promote the differential degeneration of dopaminergic midbrain neurons. Nat. Neurosci. 8 (2005) 1742-1751
61. Andrews Z.B., et al. Uncoupling protein-2 is critical for nigral dopamine cell survival in a mouse model of Parkinson's disease. J. Neurosci. 25 (2005) 184-191
62. Damier P., et al. The substantia nigra of the human brain. II. Patterns of loss of dopamine-containing neurons in Parkinson's disease. Brain 122 (1999) 1437-1448
63. Colom L.V., et al. Role of potassium channels in amyloid-induced cell death. J. Neurochem. 70 (1998) 1925-1934
64. + current in ceramide-induced caspase activation and apoptosis in cultured cortical neurons. J. Neurochem. 73 (1999) 933-941
65. Yu S.P., et al. Mediation of neuronal apoptosis by enhancement of outward potassium current. Science 278 (1997) 114-117
66. Nadeau H., et al. ROMK1 (Kir1.1) causes apoptosis and chronic silencing of hippocampal neurons. J. Neurophysiol. 84 (2000) 1062-1075
67. + channel beta-subunit and a serine/threonine kinase. Nat. Neurosci. 8 (2005) 1503-1509
68. Runnels L.W., et al. TRP-PLIK, a bifunctional protein with kinase and ion channel activities. Science 291 (2001) 1043-1047
69. Weng J., et al. Modulation of voltage-dependent Shaker family potassium channels by an aldo-keto reductase. J. Biol. Chem. 281 (2006) 15194-15200
70. Zeng H., et al. The slowpoke channel binding protein Slob from Drosophila melanogaster exhibits regulatable protein kinase activity. Neurosci. Lett. 365 (2004) 33-38
71. + channels. Proc. Natl. Acad. Sci. U. S. A. 103 (2006) 2886-2891
72. Su Z., et al. Functional consequences of methionine oxidation of hERG potassium channels. Biochem. Pharmacol. 74 (2007) 702-711
73. Berube J., et al. Hydrogen peroxide modifies the kinetics of HERG channel expressed in a mammalian cell line. J. Pharmacol. Exp. Ther. 297 (2001) 96-102
74. Caouette D., et al. Hydrogen peroxide modulates the Kv1.5 channel expressed in a mammalian cell line. Naunyn Schmiedebergs Arch. Pharmacol. 368 (2003) 479-486
75. Ciorba M.A., et al. Modulation of potassium channel function by methionine oxidation and reduction. Proc. Natl. Acad. Sci. U. S. A. 94 (1997) 9932-9937
76. + channels as a mechanism of cytoprotective neuronal silencing. EMBO J. 25 (2006) 4996-5004
77. + currents in pain-sensing dorsal root ganglion neurons. Biochem. Biophys. Res. Commun. 370 (2008) 445-449
78. Finol-Urdaneta R.K., et al. Molecular and functional differences between heart mKv1.7 channel isoforms. J. Gen. Physiol. 128 (2006) 133-145
79. Tang X.D., et al. Oxidative regulation of large conductance calcium-activated potassium channels. J. Gen. Physiol. 117 (2001) 253-274
80. Fay A.J., et al. SK channels mediate NADPH oxidase-independent reactive oxygen species production and apoptosis in granulocytes. Proc. Natl. Acad. Sci. U. S. A. 103 (2006) 17548-17553
81. Ichinari K., et al. Direct activation of the ATP-sensitive potassium channel by oxygen free radicals in guinea-pig ventricular cells: its potentiation by MgADP. J. Mol. Cell. Cardiol. 28 (1996) 1867-1877
82. Evans J.R., and Bielefeldt K. Regulation of sodium currents through oxidation and reduction of thiol residues. Neuroscience 101 (2000) 229-236
83. Kassmann M., et al. Oxidation of multiple methionine residues impairs rapid sodium channel inactivation. Pflugers Arch. 456 (2008) 1085-1095
84. Littler D.R., et al. The intracellular chloride ion channel protein CLIC1 undergoes a redox-controlled structural transition. J. Biol. Chem. 279 (2004) 9298-9305
85. Lacampagne A., et al. Effect of sulfhydryl oxidation on ionic and gating currents associated with L-type calcium channels in isolated guinea-pig ventricular myocytes. Cardiovasc. Res. 30 (1995) 799-806
86. Li Y., et al. Oxidation and reduction control of the inactivation gating of Torpedo ClC-0 chloride channels. Biophys. J. 88 (2005) 3936-3945