Immunolocalization of BK channels in hippocampal pyramidal neurons

European Journal of Neuroscience

Volumn 24, Issue 2, 2006, Pages 442-454

  Sailer, Claudia A ^a   Kaufmann, Walter A ^a,d   Kogler, Michaela ^a   Chen, Lie ^b   Sausbier, Ulrike ^c   Ottersen, Ole Petter ^d   Ruth, Peter ^c   Shipston, Michael J ^b   Knaus, Hans Günther ^a  

^a INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

^c UNIVERSITY OF TÜBINGEN   (Germany)

^d UNIVERSITY OF OSLO   (Norway)

Author keywords

Electron microscopy; Localization; Mouse hippocampal culture; Potassium channels; PSD

Indexed keywords

LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; POSTSYNAPTIC DENSITY PROTEIN 95; PROTEIN ANTIBODY;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DENDRITIC CELL; ELECTRON MICROSCOPY; FEMALE; HIPPOCAMPUS; IMMUNOCYTOCHEMISTRY; IMMUNOLOCALIZATION; IMMUNOPRECIPITATION; MOUSE; NERVE CELL CULTURE; NONHUMAN; NUCLEOTIDE SEQUENCE; POSTSYNAPTIC POTENTIAL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PYRAMIDAL NERVE CELL; SYNAPTIC TRANSMISSION;

ANIMALS; CALCIUM; CALCIUM SIGNALING; CELLS, CULTURED; DENDRITES; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICROSCOPY, ELECTRON, TRANSMISSION; PRESYNAPTIC TERMINALS; PROTEIN SUBUNITS; PYRAMIDAL CELLS; RECEPTORS, GLUTAMATE; SYNAPTIC MEMBRANES; SYNAPTIC TRANSMISSION;

EID: 33746210822     PISSN: 0953816X     EISSN: 14609568     Source Type: Journal    
DOI: 10.1111/j.1460-9568.2006.04936.x     Document Type: Article

References (44)

1. Banker, G. & Goslin, K. (1998) Culturing Nerve Cells, 2nd Edition. A Bradford Book, MIT Press, Cambridge, MA, USA.
2. Benhassine, N. & Berger, T. (2005) Homogeneous distribution of large-conductance calcium-dependent potassium channels on soma and apical dendrite of rat neocortical layer 5 pyramidal neurons. Eur. J. Neurosci., 21, 914-926.
3. Craig, A.M., Blackstone, C.D., Huganir, R.L. & Banker, G. (1993) The distribution of glutamate receptors in cultured rat hippocampal neurons: postsynaptic clustering of AMPA-selective subunits. Neuron, 10, 1055-1068.
4. Dalezios, Y., Lujan, R., Shigemoto, R., Roberts, J.D. & Somogyi, P. (2002) Enrichment of mGluR7a in the presynaptic active zones of GABAergic and non-GABAergic terminals on interneurons in the rat somatosensory cortex. Cereb. Cortex, 12, 961-974.
5. + channel subtypes in cell bodies versus nerve endings. J. Physiol. (Lond.), 519, 101-114.
6. + channels to rat Purkinje neuron function. J. Physiol. (Lond.), 548, 53-69.
7. Faber, E.S. & Sah, P. (2002) Physiological role of calcium-activated potassium currents in the rat lateral amygdala. J. Neurosci., 22, 1618-1628.
8. Fletcher, T.L., Cameron, P., De Camilli, P. & Banker, G. (1991) The distribution of synapsin I and synaptophysin in hippocampal neurons developing in culture. J. Neurosci., 11, 1617-1626.
9. Gribkoff, V.K., Starrett, J.E. Jr & Dworetzky, S.I. (2001) Maxi-K potassium channels: form, function, and modulation of a class of endogenous regulators of intracellular calcium. Neuroscientist, 7, 166-177.
10. + channels in glutamatergic hippocampal terminals and their role in spike repolarization and regulation of transmitter release. J. Neurosci., 21, 9585-9597.
11. + channels. Neuron, 31, 1027-1034.
12. + channels by interaction with a family of membrane-associated guanylate kinases. Nature, 378, 85-88.
13. Kim, E. & Sheng, M. (2004) PDZ. domain proteins of synapses. Nat. Rev. Neurosci., 5, 771-781.
14. + channels in rat brain: targeting to axons and nerve terminals. J. Neurosci., 16, 955-963.
15. Lancaster, B. & Nicoll, R.A. (1987) Properties of two calcium-activated hyperpolarizations in rat hippocampal neurones. J. Physiol. (Lond.), 389, 187-203.
16. Liao, D., Zhang, X., O'Brien, R., Ehlers, M.D. & Huganir, R.L. (1999) Regulation of morphological postsynaptic silent synapses in developing hippocampal neurons. Nat. Neurosci., 2, 37-43.
17. Matsubara, A., Laake, J.H., Davanger, S., Usami, S. & Ottersen, O.P. (1996) Organization of AMPA receptor subunits at a glutamate synapse: a quantitative immunogold analysis of hair cell synapses in the rat organ of Corti. J. Neurosci., 16, 4457-4467.
18. Nusser, Z., Lujan, R., Laube, G., Roberts, J.D., Molnar, E. & Somogyi, P. (1998) Cell type and pathway dependence of synaptic AMPA receptor number and variability in the hippocampus. Neuron, 21, 545-559.
19. + channel SK3 is localized in nerve terminals of excitatory synapses of cultured mouse hippocampal neurons. Eur. J. Neurosci., 17, 721-731.
20. 1.2) to synaptic and extrasynaptic compartments in hippocampal neurons. Eur. J. Neurosci., 19, 2109-2122.
21. Passafaro, M., Nakagawa, T., Sala, C. & Sheng, M. (2003) Induction of dendritic spines by an extracellular domain of AMPA receptor subunit GluR2. Nature, 424, 677-681.
22. Paxinos, G. & Franklin, K.B.J. (2001) The Mouse Brain in Stereotaxic Coordinates, 2nd edn. Academic Press, London.
23. + channel function in rat dorsal vagal neurones. J. Physiol. (Lond.), 527, 283-290.
24. Poolos, N.P. & Johnston, D. (1999) Calcium-activated potassium conductances contribute to action potential repolarization at the soma but not the dendrites of hippocampal CA1 pyramidal neurons. J. Neurosci., 19, 5205-5212.
25. Pyott, S.J., Glowatzki, E., Trimmer, J.S. & Aldrich, R.W. (2004) Extrasynaptic localization of inactivating calcium-activated potassium channels in mouse inner hair cells. J. Neurosci., 24, 9469-9474.
26. Raffaelli, G., Saviane, C., Mohajerani, M.H., Pedarzani, P. & Cherubini, E. (2004) BK potassium channels control transmitter release at CA3-CA3 synapses in the rat hippocampus. J. Physiol. (Lond.), 557, 147-157.
27. Rasband, M.N., Park, E.W., Zhen, D., Arbuckle, M.I., Poliak, S., Peles, E., Grant, S.G. & Trimmer, J.S. (2002) Clustering of neuronal potassium channels is independent of their interaction with PSD-95. J. Cell. Biol., 159, 663-672.
28. Robitaille, R., Garcia, M.L., Kaczorowski, G.J. & Charlton, M.P. (1993) Functional co-localization of calcium and calcium-gated potassium channels in control of transmitter release. Neuron, 11, 645-655.
29. Runden-Pran, E., Haug, F.M., Storm, J.F. & Ottersen, O.P. (2002) BK channel activity determines the extent of cell degeneration after oxygen and glucose deprivation: a study in organotypical hippocampal slice cultures. Neuroscience, 112, 277-288.
30. + currents in neurones: types, physiological roles and modulation. Trends Neurosci., 19, 150-154.
31. + channels in rat brain. J. Neurosci., 22, 9698-9707.
32. 2+-activated potassium channel subunits, SK1, SK2, and SK3 in mouse brain. Mol. Cell. Neurosci., 26, 458-469.
33. Sausbier, M., Arntz, C., Bucurenciu, I., Zhao, H., Zhou, X.B., Sausbier, U., Feil, S., Kamm, S., Essin, K., Sailer, C.A., Abdullah, U., Krippeit-Drews, P., Feil, R., Hofmann, F., Knaus, H.G., Kenyon, C., Shipston, M.J., Storm, J.F., Neuhuber, W., Korth, M., Schubert, R., Gollasch, M. & Ruth, P. (2005) Elevated blood pressure linked to primary hyperaldosteronism and impaired vasodilation in BK channel-deficient mice. Circulation, 112, 60-68.
34. + channel deficiency. Proc. Natl Acad. Sci. USA, 101, 9474-9478.
35. + channels in spike broadening during repetitive firing in rat hippocampal pyramidal cells. J. Physiol. (Lond.), 521, 135-146.
36. Shi, S.H., Jan, L.Y. & Jan, Y.N. (2003) Hippocampal neuronal polarity specified by spatially localized mPar3/mPar6 and PI 3-kinase activity. Cell, 112, 63-75.
37. Storm, J.F. (1987) Action potential repolarization and a fast after-hyperpolarization in rat hippocampal pyramidal cells. J. Physiol. (Lond.), 385, 733-759.
38. + current in mouse neocortical pyramidal neurons. J. Neurosci., 23, 3639-3648.
39. Takumi, Y., Ramirez-Leon, V., Laake, P., Rinvik, E. & Ottersen, O.P. (1999) Different modes of expression of AMPA and NMDA receptors in hippocampal synapses. Nat. Neurosci., 2, 618-624.
40. Tian, L., Coghill, L.S., McClafferty, H., MacDonald, S.H., Antoni, F.A., Ruth, P., Knaus, H.G. & Shipston, M.J. (2004) Distinct stoichiometry of BKCa channel tetramer phosphorylation specifies channel activation and inhibition by cAMP-dependent protein kinase. Proc. Natl Acad. Sci. USA, 101, 11897-11902.
41. Trimmer, J.S. & Rhodes, K.J. (2004) Localization of voltage-gated ion channels in mammalian brain. Annu. Rev. Physiol., 66, 477-519.
42. Wanner, S.G., Koch, R.O., Koschak, A., Trieb, M., Garcia, M.L., Kaczorowski, G.J. & Knaus, H.G. (1999) High-conductance calcium-activated potassium channels in rat brain: pharmacology, distribution, and subunit composition. Biochemistry, 38, 5392-5400.
43. Womack, M.D. & Khodakhah, K. (2003) Somatic and dendritic small-conductance calcium-activated potassium channels regulate the output of cerebellar purkinje neurons. J. Neurosci., 23, 2600-2607.
44. Xu, J.W. & Slaughter, M.M. (2005) Large-conductance calcium-activated potassium channels facilitate transmitter release in salamander rod synapse. J. Neurosci., 25, 7660-7668.