Oxidative regulation of large conductance calcium-activated potassium channels

Journal of General Physiology

Volumn 117, Issue 3, 2001, Pages 253-273

  Tang, Xiang D ^a   Daggett, Heather ^a   Hanner, Markus ^b,f   Garcia, Maria L ^b   McManus, Owen B ^b   Brot, Nathan ^c   Weissbach, Herbert ^d   Heinemann, Stefan H ^e   Hoshi, Toshinori ^a  

^a UNIVERSITY OF IOWA   (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

^c WEILL CORNELL MEDICAL CENTER   (United States)

^d FLORIDA ATLANTIC UNIVERSITY   (United States)

^e JENA UNIVERSITY HOSPITAL   (Germany)

^f INTERCELL AG   (Austria)

Author keywords

Chloramine T; Cysteine; Methionine; Methionine sulfoxide; Methionine sulfoxide reductase

Indexed keywords

4 CHLOROMERCURIBENZOIC ACID; 5,5' DITHIOBIS(2 NITROBENZOIC ACID); CALCIUM; CYSTEINE; HYDROGEN PEROXIDE; METHANETHIOSULFONATE ETHYLAMMONIUM DERIVATIVE; METHIONINE; METHIONINE SULFOXIDE REDUCTASE; NITROGEN; OXIDOREDUCTASE; POTASSIUM; POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT; REACTIVE OXYGEN METABOLITE; SULFONIC ACID DERIVATIVE; TOSYLCHLORAMIDE SODIUM; UNCLASSIFIED DRUG;

CELL METABOLISM; CHANNEL GATING; CONDUCTANCE; CONFERENCE PAPER; CONTROLLED STUDY; ELECTROPHYSIOLOGY; OXIDATION; REGULATORY MECHANISM; STEADY STATE;

ANIMALS; CALCIUM; CELL CULTURE TECHNIQUES; CHLORAMINES; ELECTROPHYSIOLOGY; HUMANS; ION CHANNEL GATING; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; METHIONINE; OXIDATION-REDUCTION; POLYMERASE CHAIN REACTION; POTASSIUM CHANNELS; POTASSIUM CHANNELS, CALCIUM-ACTIVATED; REACTIVE OXYGEN SPECIES; TOSYL COMPOUNDS; UP-REGULATION;

EID: 0035014014     PISSN: 00221295     EISSN: None     Source Type: Journal    
DOI: 10.1085/jgp.117.3.253     Document Type: Conference Paper

References (126)

1. Calcium-activated potassium channels expressed from cloned complementary DNAs
2. + channels
3. A component of calcium-activated potassium channels encoded by the Drosophila slo locus
4. Behavioral and electrophysiological analysis of Ca-activated K-channel transgenes in Drosophila
5. Reperfusion injury of postischemic tissues
6. Ca channel activity
7. Properties of single calcium-activated potassium channels in cultured rat muscle
8. Proteins released from stimulated neutrophils contain very high levels of oxidized methionine
9. Ionic channel rundown in excised membrane patches
10. + channels in smooth muscle cells
11. Carbon dioxide stimulates peroxynitrite-mediated nitration of tyrosine residues and inhibits oxidation of methionine residues of glutamine synthetase - Both modifications mimic effects of adenylylation
12. Development of hydrophobicity parameters to analyze proteins which bear post- or cotranslational modifications
13. Potassium channels in vascular smooth muscle
14. Vasoregulation by the beta1 subunit of the calcium-activated potassium channel
15. + channels in rat cerebral artery smooth muscle cells
16. Oxidant, mitochondria and calcium: An overview
17. Differential expression of the alpha and beta subunits of the large-conductance calcium-activated potassium channel: Implication for channel diversity
18. + channels by methionine oxidation
19. The internal quaternary ammonium receptor site of Shaker potassium channels
20. Modulation of potassium channel function by methionine oxidation and reduction
21. + channels by methionine oxidation: Effect of nitric oxide and vitamin C
22. + channel
23. + channels
24. + channels
25. + channel and its structural implications
26. Role of the S4 segment in a voltage-dependent calcium-sensitive potassium (hSlo) channel
27. + channels
28. Nitric oxide and coronary endothelial dysfunction in humans
29. Atomic scale structure and functional models of voltage-gated potassium channels
30. Reduction of methionine sulfoxide to methionine by Escherichia coli
31. Free radicals in brain metabolism and pathology
32. The use of group-specific reagents
33. Mechanisms of hair cell tuning
34. Methionine modification impairs the C5-cleavage function of cobra venom factor-dependent C3/C5 convertase
35. Decrease in peptide methionine sulfoxide reductase in Alzheimer's disease brain
36. Loss of conformational stability in calmodulin upon methionine oxidation
37. Redox modulation of large conductance calcium-activated potassium channels in CA1 pyramidal neurons from adult rat hippocampus
38. Stroke. Revolution in therapy
39. Reactive oxygen species and the central nervous system
40. + channels
41. Molecular and functional characterization of a rat brain Kvβ 3 potassium channel subunit
42. + channels
43. Site-directed mutagenesis by overlap extension using the polymerase chain reaction
44. Prevention of rundown in electrophysiological recording
45. 2+
46. 2+
47. Regulation of cell function by methionine oxidation and reduction
48. Ways and means for left shifts in the MaxiK channel
49. Oxidative stress and the pathogenesis of Parkinson's disease
50. High-conductance calcium-activated potassium channels: Structure, pharmacology, and function
51. Substituted-cysteine accessibility method
52. Interaction of reactive oxygen species with ion transport mechanisms
53. Molecular cloning and functional expression of a human peptide methionine sulfoxide reductase (hMsrA)
54. + channels gated by voltage and ions
55. Methionine residues as endogenous antioxidants in proteins
56. Calcium-activated potassium channels in adrenal chromaffin cells
57. + channel
58. Distinct and specific functions of cGMP-dependent protein kinases
59. Oxidative stress hypothesis in Alzheimer's disease
60. The physiological role of calcium-dependent channels
61. Calcium-activated potassium channels: Regulation by calcium
62. Kinetic states and modes of single large-conductance calcium-activated potassium channels in cultured rat skeletal muscle
63. + channels in rat skeletal muscle
64. A calcium switch for the functional coupling between alpha (hslo) and beta subunits (KV, Ca beta) of maxi K channels
65. + channel, a distinct member of voltage-dependent ion channels with seven N-terminal transmembrane segments (S0-S6), an extracellular N terminus, and an intracellular (S9-S10) C terminus
66. The gating of single calcium-dependent potassium channels is described by an activation/blockade mechanism
67. Potassium channel diversity in vascular smooth muscle cells
68. Functional methionines in the collagen/gelatin binding domain of plasma fibronectin: Effects of chemical modification by chloramine T
69. 2+ binding reactions
70. Overexpression of peptide-methionine sulfoxide reductase in Saccharomyces cerevisiae and human T cells provides them with high resistance to oxidative stress
71. Cloning and expression of a mammalian gene involved in the reduction of methionine sulfoxide residues in proteins
72. Relationship between accessibility and reactivity of Lys, Met and Tyr in subtilisins DY and Carlsberg
73. 2+-activated potassium channels by retaining the gating in the bursting states
74. 2+-independent mechanism
75. 2+ channels
76. Metals and free radicals in neurodegeneration
77. Reperfusion injury and its pharmacologic modification
78. Recording from calcium-activated potassium channels
79. Different modulation of Ca-activated K channels by the intracellular redox potential in pulmonary and ear arterial smooth muscle cells of the rabbit
80. +-channel activation gating
81. 2+ Spark/STOC coupling and elevated blood pressure
82. Involvement of methionine residues in the fast inactivation mechanism of the sodium current from toad skeletal muscle fibers
83. Cloning, sequencing, and expression of the Escherichia coli peptide methionine sulfoxide reductase gene
84. A molecular mechanism for electrical tuning of cochlear hair cells
85. + channels altered by presence of β-subunit
86. + channels suggests that the gating includes transitions through intermediate or secondary states. A mechanism for flickers
87. 2+ suggest a two-tiered allosteric gating mechanism
88. Vascular effects of oxygen-derived free radicals
89. Regulation of fast inactivation of cloned mammalian IK(A) channels by cysteine oxidation
90. + channels in hypertension
91. The role of nitric oxide synthase/nitric oxide in vascular smooth muscle control
92. Modification of C-type inactivating Shaker potassium channels by chloramine-T
93. A novel calcium-sensing domain in the BK channel
94. Transplantable sites confer calcium sensitivity to BK channels
95. Selective oxidation of methionine residues in proteins
96. Tetraethylammonium block of Slowpoke calcium-activated potassium channels expressed in Xenopus oocytes: Evidence for tetrameric channel formation
97. Heparinase II from Flavobacterium heparinum. Role of cysteine in enzymatic activity as probed by chemical modification and site-directed mutagenesis
98. + channel, expressed in oocytes
99. Characterization of calcium-activated potassium channels in single smooth muscle cells using the patch-clamp technique
100. + channels using two-dimensional dwell-time distributions
101. Nitric oxide-cyclic GMP pathway in brain slices
102. Reactive oxygen-mediated protein oxidation in aging and disease
103. Redox signaling: Nitrosylation and related target interactions of nitric oxide
104. + channel (hslo)
105. Cysteine-modifying reagents alter the gating of the rat cloned potassium channel Kvl.4
106. Singlet oxygen inactivates fibrinogen, factor V, factor VIII, factor X, and platelet aggregation of human blood
107. Oxidants as stimulators of signal transduction
108. Complex voltage-dependent behavior of single unliganded calcium-sensitive potassium channels
109. Molecular constituents of maxi KCa channels in human coronary smooth muscle: Predominant alpha + beta subunit complexes
110. Contrasting effects of intracellular redox couples on the regulation of maxi-K channels in isolated myocytes from rabbit pulmonary artery
111. + channels: Metabolic regulation
112. Ca, a unique member of the voltage-gated K channel superfamily
113. Signalling by cGMP-dependent protein kinases
114. Calcium-activated potassium channels
115. Oxidation of methionyl residues in proteins: Tools, targets and reversal
116. Ca channel cloned from myometrium
117. + channels: An additional transmembrane region at the N terminus
118. Removal of sodium channel inactivation in squid axon by the oxidant chloramine-T
119. + channels in smooth muscle cells
120. High-conductance calcium-activated potassium channels in rat brain: Pharmacology, distribution, and subunit composition
121. Ca channels determined by a separate domain
122. + (BK) channels
123. + channels by external cations
124. The moving parts of voltage-gated ion channels
125. + channel
126. Role of nitric oxide in the neural control of cardiovascular function