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Volumn 34, Issue 3, 2010, Pages 408-437

Will testing for apolipoprotein E assist in tailoring dementia risk reduction? A review

Author keywords

Alzheimer's disease; Apolipoprotein E; Dementia; Gene environment interactions; Risk factors; Systematic review

Indexed keywords

ACETYLSALICYLIC ACID; ANTACID AGENT; ANTIHYPERTENSIVE AGENT; ANTILIPEMIC AGENT; ANTIPERSPIRANT AGENT; APOLIPOPROTEIN E; APOLIPOPROTEIN E EPSILON 4; C REACTIVE PROTEIN; CORTICOSTEROID; ESTRADIOL; HOMOCYSTEINE; NONSTEROID ANTIINFLAMMATORY AGENT; SATURATED FATTY ACID; UNCLASSIFIED DRUG;

EID: 72449200083     PISSN: 01497634     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neubiorev.2009.08.007     Document Type: Review
Times cited : (17)

References (135)
  • 2
    • 33645669688 scopus 로고    scopus 로고
    • The relation of cigarette smoking to incident Alzheimer's disease in a biracial urban community population
    • Aggarwal N.T., Bienias J.L., Bennett D.A., Wilson R.S., Morris M.C., Schneider J.A., et al. The relation of cigarette smoking to incident Alzheimer's disease in a biracial urban community population. Neuroepidemiology 26 (2006) 140-146
    • (2006) Neuroepidemiology , vol.26 , pp. 140-146
    • Aggarwal, N.T.1    Bienias, J.L.2    Bennett, D.A.3    Wilson, R.S.4    Morris, M.C.5    Schneider, J.A.6
  • 3
    • 48649110601 scopus 로고    scopus 로고
    • Cholesterol as a risk factor for dementia and cognitive decline: a systematic review of prospective studies with meta-analysis
    • Anstey K.J., Lipnicki D.M., and Low L.F. Cholesterol as a risk factor for dementia and cognitive decline: a systematic review of prospective studies with meta-analysis. Am. J. Geriatr. Psychiatry 16 (2008) 343-354
    • (2008) Am. J. Geriatr. Psychiatry , vol.16 , pp. 343-354
    • Anstey, K.J.1    Lipnicki, D.M.2    Low, L.F.3
  • 4
    • 34547679439 scopus 로고    scopus 로고
    • Smoking as a risk factor for dementia and cognitive decline: a meta-analysis of prospective studies
    • Anstey K.J., von Sanden C., Salim A., and O'Kearney R. Smoking as a risk factor for dementia and cognitive decline: a meta-analysis of prospective studies. Am. J. Epidemiol. (2007) 116
    • (2007) Am. J. Epidemiol. , pp. 116
    • Anstey, K.J.1    von Sanden, C.2    Salim, A.3    O'Kearney, R.4
  • 5
    • 4544259817 scopus 로고    scopus 로고
    • Alcohol drinking in middle age and subsequent risk of mild cognitive impairment and dementia in old age: a prospective population based study
    • Anttila T., Helkala E.-L., Viitanen M., Kareholt I., Fratiglioni L., Winblad B., et al. Alcohol drinking in middle age and subsequent risk of mild cognitive impairment and dementia in old age: a prospective population based study. Br. Med. J. 329 (2004) 530-539
    • (2004) Br. Med. J. , vol.329 , pp. 530-539
    • Anttila, T.1    Helkala, E.-L.2    Viitanen, M.3    Kareholt, I.4    Fratiglioni, L.5    Winblad, B.6
  • 6
  • 8
    • 0037461327 scopus 로고    scopus 로고
    • Comparison of Alzheimer's disease risk factors in white and African American families
    • Bachman D.L., Green R.C., Benke K.S., Cupples L.A., and Farrer L.A. Comparison of Alzheimer's disease risk factors in white and African American families. Neurology 60 (2003) 1372-1374
    • (2003) Neurology , vol.60 , pp. 1372-1374
    • Bachman, D.L.1    Green, R.C.2    Benke, K.S.3    Cupples, L.A.4    Farrer, L.A.5
  • 11
    • 0032461009 scopus 로고    scopus 로고
    • Herpes simplex virus type 1 in the brain, apolipoprotein E genotype and Alzheimer's disease
    • Beffert U. Herpes simplex virus type 1 in the brain, apolipoprotein E genotype and Alzheimer's disease. McGill J. Med. 4 (1998) 4-8
    • (1998) McGill J. Med. , vol.4 , pp. 4-8
    • Beffert, U.1
  • 12
    • 42249107660 scopus 로고    scopus 로고
    • Obesity and central obesity as risk factors for incident dementia and its subtypes: a systematic review and meta-analysis
    • Beydoun M.A., Beydoun H.A., and Wang Y. Obesity and central obesity as risk factors for incident dementia and its subtypes: a systematic review and meta-analysis. Obes. Rev. 9 (2008) 204-218
    • (2008) Obes. Rev. , vol.9 , pp. 204-218
    • Beydoun, M.A.1    Beydoun, H.A.2    Wang, Y.3
  • 14
    • 17744410836 scopus 로고    scopus 로고
    • ApoE-4 and age at onset of Alzheimer's disease: the NIMH genetics initiative
    • Blacker D., Haines J.L., Rodes L., Terwedow H., Go R.C.P., Harrell L.E., et al. ApoE-4 and age at onset of Alzheimer's disease: the NIMH genetics initiative. Neurology 48 (1997) 139-147
    • (1997) Neurology , vol.48 , pp. 139-147
    • Blacker, D.1    Haines, J.L.2    Rodes, L.3    Terwedow, H.4    Go, R.C.P.5    Harrell, L.E.6
  • 16
    • 33845588901 scopus 로고    scopus 로고
    • APOE genotype and cholesterol levels in Lewy body dementia and Alzheimer disease: Investigating genotype-phenotype effect on disease risk
    • Borroni B., Grassi M., Costanzi C., Archetti S., Caimi L., and Padovani A. APOE genotype and cholesterol levels in Lewy body dementia and Alzheimer disease: Investigating genotype-phenotype effect on disease risk. Am. J. Geriatr. Psychiatry 14 (2006) 1022-1031
    • (2006) Am. J. Geriatr. Psychiatry , vol.14 , pp. 1022-1031
    • Borroni, B.1    Grassi, M.2    Costanzi, C.3    Archetti, S.4    Caimi, L.5    Padovani, A.6
  • 17
    • 0035873429 scopus 로고    scopus 로고
    • Commentary: facing the challenge of gene-environment interaction: the two-by-four table and beyond
    • Botto L.D., and Khoury M.J. Commentary: facing the challenge of gene-environment interaction: the two-by-four table and beyond. Am. J. Epidemiol. 153 (2001) 1016-1020
    • (2001) Am. J. Epidemiol. , vol.153 , pp. 1016-1020
    • Botto, L.D.1    Khoury, M.J.2
  • 19
    • 38349146483 scopus 로고    scopus 로고
    • Apolipoprotein E and Alzheimer's disease: molecular mechanisms and therapeutic opportunities
    • Cedazo-Mínguez A. Apolipoprotein E and Alzheimer's disease: molecular mechanisms and therapeutic opportunities. J. Cell. Mol. Med. 11 (2007) 1227-1238
    • (2007) J. Cell. Mol. Med. , vol.11 , pp. 1227-1238
    • Cedazo-Mínguez, A.1
  • 21
    • 0027194791 scopus 로고
    • Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families
    • Corder E.H., Saunders A.M., Strittmatter W.J., Schmechel D.E., Gaskell P.C., Small G.W., et al. Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. Science 261 (1993) 921-923
    • (1993) Science , vol.261 , pp. 921-923
    • Corder, E.H.1    Saunders, A.M.2    Strittmatter, W.J.3    Schmechel, D.E.4    Gaskell, P.C.5    Small, G.W.6
  • 22
    • 1842840885 scopus 로고    scopus 로고
    • Aspirin, NSAIDs, risk of dementia, and influence of the apolipoprotein E epsilon 4 allele in an elderly population
    • Cornelius C., Fastbom J., Winblad B., and Viitanen M. Aspirin, NSAIDs, risk of dementia, and influence of the apolipoprotein E epsilon 4 allele in an elderly population. Neuroepidemiology 23 (2004) 135-143
    • (2004) Neuroepidemiology , vol.23 , pp. 135-143
    • Cornelius, C.1    Fastbom, J.2    Winblad, B.3    Viitanen, M.4
  • 23
    • 13944270314 scopus 로고    scopus 로고
    • The Women's Health Initiative Memory Study: findings and implications for treatment
    • Craig M.C., Maki P.M., and Murphy D.G. The Women's Health Initiative Memory Study: findings and implications for treatment. Lancet Neurol. 4 (2005) 190-194
    • (2005) Lancet Neurol. , vol.4 , pp. 190-194
    • Craig, M.C.1    Maki, P.M.2    Murphy, D.G.3
  • 24
    • 67649252917 scopus 로고    scopus 로고
    • Use of statins and incidence of dementia and cognitive impairment without dementia in a cohort study
    • Cramer C., Haan M.N., Galea S., Langa K.M., and Kalbfleisch J.D. Use of statins and incidence of dementia and cognitive impairment without dementia in a cohort study. Neurology 71 (2008) 344-350
    • (2008) Neurology , vol.71 , pp. 344-350
    • Cramer, C.1    Haan, M.N.2    Galea, S.3    Langa, K.M.4    Kalbfleisch, J.D.5
  • 26
    • 33747878212 scopus 로고    scopus 로고
    • Fruit and vegetable juices and Alzheimer's disease: The Kame Project
    • Dai Q., Borenstein A.R., Wu Y., Jackson J.C., and Larson E.B. Fruit and vegetable juices and Alzheimer's disease: The Kame Project. Am. J. Med. 119 (2006) 751-759
    • (2006) Am. J. Med. , vol.119 , pp. 751-759
    • Dai, Q.1    Borenstein, A.R.2    Wu, Y.3    Jackson, J.C.4    Larson, E.B.5
  • 27
    • 11844255796 scopus 로고    scopus 로고
    • Meta-analysis of nonsteroidal antiinflammatory drug use and risk of dementia
    • de Craen A.J.M., Gussekloo J., Vrijsen B., and Westendorp R.G.J. Meta-analysis of nonsteroidal antiinflammatory drug use and risk of dementia. Am. J. Epidemiol. 161 (2005) 114-120
    • (2005) Am. J. Epidemiol. , vol.161 , pp. 114-120
    • de Craen, A.J.M.1    Gussekloo, J.2    Vrijsen, B.3    Westendorp, R.G.J.4
  • 30
    • 0030006546 scopus 로고    scopus 로고
    • Alzheimer's disease: interaction of apolipoprotein E genotype, family history of dementia, gender, education, ethnicity, and age of onset
    • Duara R., Barker W.W., Lopez-Alberola R., Loewenstein D.A., Grau L.B., Gilchrist D., et al. Alzheimer's disease: interaction of apolipoprotein E genotype, family history of dementia, gender, education, ethnicity, and age of onset. Neurology 46 (1996) 1575-1579
    • (1996) Neurology , vol.46 , pp. 1575-1579
    • Duara, R.1    Barker, W.W.2    Lopez-Alberola, R.3    Loewenstein, D.A.4    Grau, L.B.5    Gilchrist, D.6
  • 31
    • 18144419392 scopus 로고    scopus 로고
    • APOE genotype, cholesterol level, lipid-lowering treatment, and dementia: The Three-City Study
    • Dufouil C., Richard F., Fiavet N., Dartigues J.F., Ritchie K., Tzourio C., et al. APOE genotype, cholesterol level, lipid-lowering treatment, and dementia: The Three-City Study. Neurology 64 (2005) 1531-1538
    • (2005) Neurology , vol.64 , pp. 1531-1538
    • Dufouil, C.1    Richard, F.2    Fiavet, N.3    Dartigues, J.F.4    Ritchie, K.5    Tzourio, C.6
  • 33
    • 0347020249 scopus 로고    scopus 로고
    • Diet and dementia, is there a link? A systematic review
    • Ernst E. Diet and dementia, is there a link? A systematic review. Nutr. Neurosci. 2 (1999) 1-6
    • (1999) Nutr. Neurosci. , vol.2 , pp. 1-6
    • Ernst, E.1
  • 34
    • 0033958076 scopus 로고    scopus 로고
    • Serum cholesterol, APOE genotype, and the risk of Alzheimer's disease: a population-based study of African Americans
    • Evans R.M., Emsley C.L., Gao S., Sahota A., Hall K.S., Farlow M.R., et al. Serum cholesterol, APOE genotype, and the risk of Alzheimer's disease: a population-based study of African Americans. Neurology 54 (2000) 240-242
    • (2000) Neurology , vol.54 , pp. 240-242
    • Evans, R.M.1    Emsley, C.L.2    Gao, S.3    Sahota, A.4    Hall, K.S.5    Farlow, M.R.6
  • 35
    • 0028889485 scopus 로고
    • Statement on use of apolipoprotein E testing for Alzheimer disease
    • Farrer L.A., Brin M.F., Elsas L., Goate A., Kennedy J., Mayeux R., et al. Statement on use of apolipoprotein E testing for Alzheimer disease. JAMA 274 (1995) 1627-1629
    • (1995) JAMA , vol.274 , pp. 1627-1629
    • Farrer, L.A.1    Brin, M.F.2    Elsas, L.3    Goate, A.4    Kennedy, J.5    Mayeux, R.6
  • 36
    • 0030823158 scopus 로고    scopus 로고
    • Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease: a meta-analysis
    • Farrer L.A.P., Cupples L.A.P., Haines J.L.P., Hyman B.M.D.P., Kukull W.A.P., Mayeux R.M.D., et al. Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease: a meta-analysis. JAMA 278 (1997) 1349-1356
    • (1997) JAMA , vol.278 , pp. 1349-1356
    • Farrer, L.A.P.1    Cupples, L.A.P.2    Haines, J.L.P.3    Hyman, B.M.D.P.4    Kukull, W.A.P.5    Mayeux, R.M.D.6
  • 40
    • 33947589960 scopus 로고    scopus 로고
    • The risk of dementia with increased body mass index
    • Gorospe E.C., and Dave J.K. The risk of dementia with increased body mass index. Age Ageing 36 (2007) 23-29
    • (2007) Age Ageing , vol.36 , pp. 23-29
    • Gorospe, E.C.1    Dave, J.K.2
  • 43
    • 53649092389 scopus 로고    scopus 로고
    • C-reactive protein and rate of dementia in carriers and non carriers of apolipoprotein APOE4 genotype
    • Haan M.N., Aiello A.E., West N.A., and Jagust W.J. C-reactive protein and rate of dementia in carriers and non carriers of apolipoprotein APOE4 genotype. Neurobiol. Aging 29 (2008) 1774-1782
    • (2008) Neurobiol. Aging , vol.29 , pp. 1774-1782
    • Haan, M.N.1    Aiello, A.E.2    West, N.A.3    Jagust, W.J.4
  • 44
    • 0033532737 scopus 로고    scopus 로고
    • The role of APOE epsilon4 in modulating effects of other risk factors for cognitive decline in elderly persons
    • Haan M.N., Shemanski L., Jagust W.J., Manolio T.A., and Kuller L. The role of APOE epsilon4 in modulating effects of other risk factors for cognitive decline in elderly persons. JAMA 282 (1999) 40-46
    • (1999) JAMA , vol.282 , pp. 40-46
    • Haan, M.N.1    Shemanski, L.2    Jagust, W.J.3    Manolio, T.A.4    Kuller, L.5
  • 45
    • 33644911218 scopus 로고    scopus 로고
    • Cholesterol, APOE genotype, and Alzheimer disease: an epidemiologic study of Nigerian Yoruba
    • Hall K., Murrell J., Ogunniyi A., Deeg M., Baiyewu O., Gao S., et al. Cholesterol, APOE genotype, and Alzheimer disease: an epidemiologic study of Nigerian Yoruba. Neurology 66 (2006) 223-227
    • (2006) Neurology , vol.66 , pp. 223-227
    • Hall, K.1    Murrell, J.2    Ogunniyi, A.3    Deeg, M.4    Baiyewu, O.5    Gao, S.6
  • 47
    • 0031026879 scopus 로고    scopus 로고
    • Atherosclerosis, apolipoprotein E, and prevalence of dementia and Alzheimer's disease in the Rotterdam Study
    • Hofman A., Ott A., Breteler M.M., Bots M.L., Slooter A.J., van Harskamp F., et al. Atherosclerosis, apolipoprotein E, and prevalence of dementia and Alzheimer's disease in the Rotterdam Study. Lancet 349 (1997) 151-154
    • (1997) Lancet , vol.349 , pp. 151-154
    • Hofman, A.1    Ott, A.2    Breteler, M.M.3    Bots, M.L.4    Slooter, A.J.5    van Harskamp, F.6
  • 51
    • 38349059065 scopus 로고    scopus 로고
    • Enhanced risk for Alzheimer disease in persons with Type 2 diabetes and APOE epsilon 4: The Cardiovascular Health Study Cognition Study
    • Irie F., Fitzpatrick A.L., Lopez O.L., Kuller L.H., Peila R., Newman A.B., et al. Enhanced risk for Alzheimer disease in persons with Type 2 diabetes and APOE epsilon 4: The Cardiovascular Health Study Cognition Study. Arch. Neurol. 65 (2008) 89-93
    • (2008) Arch. Neurol. , vol.65 , pp. 89-93
    • Irie, F.1    Fitzpatrick, A.L.2    Lopez, O.L.3    Kuller, L.H.4    Peila, R.5    Newman, A.B.6
  • 52
    • 48949086025 scopus 로고    scopus 로고
    • Apolipoprotein E 4 allele genotype and the effect of depressive symptoms on the risk of dementia in men: The Honolulu-Asia aging study
    • Irie F., Masaki K.H., Petrovitch H., Abbott R.D., Ross G.W., Taaffe D.R., et al. Apolipoprotein E 4 allele genotype and the effect of depressive symptoms on the risk of dementia in men: The Honolulu-Asia aging study. Arch. Gen. Psychiatry 65 (2008) 906-912
    • (2008) Arch. Gen. Psychiatry , vol.65 , pp. 906-912
    • Irie, F.1    Masaki, K.H.2    Petrovitch, H.3    Abbott, R.D.4    Ross, G.W.5    Taaffe, D.R.6
  • 53
    • 0031565438 scopus 로고    scopus 로고
    • Herpes simplex virus and risk of Alzheimer's disease
    • Itabashi S., Arai H., Matsui T., Higuchi S., and Sasaki H. Herpes simplex virus and risk of Alzheimer's disease. Lancet 349 (1997) 1102
    • (1997) Lancet , vol.349 , pp. 1102
    • Itabashi, S.1    Arai, H.2    Matsui, T.3    Higuchi, S.4    Sasaki, H.5
  • 57
    • 0029072551 scopus 로고
    • Interactions of apolipoprotein E genotype, total cholesterol level, age, and sex in prediction of Alzheimer's disease: a case-control study
    • Jarvik G.P., Wijsman E.M., Kukull W.A., Schellenberg G.D., Yu C., and Larson E.B. Interactions of apolipoprotein E genotype, total cholesterol level, age, and sex in prediction of Alzheimer's disease: a case-control study. Neurology 45 (1995) 1092-1096
    • (1995) Neurology , vol.45 , pp. 1092-1096
    • Jarvik, G.P.1    Wijsman, E.M.2    Kukull, W.A.3    Schellenberg, G.D.4    Yu, C.5    Larson, E.B.6
  • 58
    • 37849053122 scopus 로고    scopus 로고
    • Joint effect of stroke and APOE 4 on dementia risk: The Canadian Study of Health and Aging
    • Jin Y.P., Ostbye T., Feightner J.W., Di Legge S., and Hachinski V. Joint effect of stroke and APOE 4 on dementia risk: The Canadian Study of Health and Aging. Neurology 70 (2008) 9-16
    • (2008) Neurology , vol.70 , pp. 9-16
    • Jin, Y.P.1    Ostbye, T.2    Feightner, J.W.3    Di Legge, S.4    Hachinski, V.5
  • 59
    • 0033768853 scopus 로고    scopus 로고
    • Relationships between cerebrovascular events, APOE polymorphism and Alzheimer's disease in a community sample
    • Johnston J.M., Nazar-Stewart V., Kelsey S.F., Kamboh M.I., and Ganguli M. Relationships between cerebrovascular events, APOE polymorphism and Alzheimer's disease in a community sample. Neuroepidemiology 19 (2000) 320-326
    • (2000) Neuroepidemiology , vol.19 , pp. 320-326
    • Johnston, J.M.1    Nazar-Stewart, V.2    Kelsey, S.F.3    Kamboh, M.I.4    Ganguli, M.5
  • 60
    • 49049122193 scopus 로고    scopus 로고
    • Alzheimer's disease and vascular dementia in developing countries: prevalence, management, and risk factors
    • Kalaria R.N., Maestre G.E., Arizaga R., Friedland R.P., Galasko D., Hall K., et al. Alzheimer's disease and vascular dementia in developing countries: prevalence, management, and risk factors. Lancet Neurol. 7 (2008) 812-826
    • (2008) Lancet Neurol. , vol.7 , pp. 812-826
    • Kalaria, R.N.1    Maestre, G.E.2    Arizaga, R.3    Friedland, R.P.4    Galasko, D.5    Hall, K.6
  • 62
    • 26444463825 scopus 로고    scopus 로고
    • Obesity and vascular risk factors at midlife and the risk of dementia and Alzheimer disease
    • Kivipelto M., Ngandu T., Fratiglioni L., Viitanen M., Kareholt I., Winblad B., et al. Obesity and vascular risk factors at midlife and the risk of dementia and Alzheimer disease. Arch. Neurol. 62 (2005) 1556-1560
    • (2005) Arch. Neurol. , vol.62 , pp. 1556-1560
    • Kivipelto, M.1    Ngandu, T.2    Fratiglioni, L.3    Viitanen, M.4    Kareholt, I.5    Winblad, B.6
  • 64
    • 35549009758 scopus 로고    scopus 로고
    • Estimating interaction on an additive scale between continuous determinants in a logistic regression model
    • Knol M.J., van der Tweel I., Grobbee D.E., Numans M.E., and Geerlings M.I. Estimating interaction on an additive scale between continuous determinants in a logistic regression model. Int. J. Epidemiol. 36 (2007) 1111-1118
    • (2007) Int. J. Epidemiol. , vol.36 , pp. 1111-1118
    • Knol, M.J.1    van der Tweel, I.2    Grobbee, D.E.3    Numans, M.E.4    Geerlings, M.I.5
  • 65
    • 33846445278 scopus 로고    scopus 로고
    • Green Banana*: dementia epidemiology research: it is time to modify the focus of research
    • Kuller L.H. Green Banana*: dementia epidemiology research: it is time to modify the focus of research. J. Gerontol. A Biol. Sci. Med. Sci. 61 (2006) 1314-1318
    • (2006) J. Gerontol. A Biol. Sci. Med. Sci. , vol.61 , pp. 1314-1318
    • Kuller, L.H.1
  • 66
    • 9844229370 scopus 로고    scopus 로고
    • Association between features of the insulin resistance syndrome and Alzheimer's disease independently of apolipoprotein E4 phenotype: cross sectional population based study
    • Kuusisto J., Koivisto K., Mykkanen L., Helkala E.L., Vanhanen M., Hanninen T., et al. Association between features of the insulin resistance syndrome and Alzheimer's disease independently of apolipoprotein E4 phenotype: cross sectional population based study. Br. Med. J. 315 (1997) 1045-1049
    • (1997) Br. Med. J. , vol.315 , pp. 1045-1049
    • Kuusisto, J.1    Koivisto, K.2    Mykkanen, L.3    Helkala, E.L.4    Vanhanen, M.5    Hanninen, T.6
  • 68
    • 2342608923 scopus 로고    scopus 로고
    • Midlife dietary intake of antioxidants and risk of late-life incident dementia: the Honolulu-Asia aging study
    • Laurin D., Masaki K.H., Foley D.J., White L.R., and Launer L.J. Midlife dietary intake of antioxidants and risk of late-life incident dementia: the Honolulu-Asia aging study. Am. J. Epidemiol. 159 (2004) 959-967
    • (2004) Am. J. Epidemiol. , vol.159 , pp. 959-967
    • Laurin, D.1    Masaki, K.H.2    Foley, D.J.3    White, L.R.4    Launer, L.J.5
  • 69
    • 36048930156 scopus 로고    scopus 로고
    • Ankle-to-brachial index and dementia. The Honolulu-Asia Aging Study
    • Laurin D., Masaki K.H., White L.R., and Launer L.J. Ankle-to-brachial index and dementia. The Honolulu-Asia Aging Study. Circulation (2007)
    • (2007) Circulation
    • Laurin, D.1    Masaki, K.H.2    White, L.R.3    Launer, L.J.4
  • 71
    • 0035925762 scopus 로고    scopus 로고
    • Hormone replacement therapy and cognition: systematic review and meta-analysis
    • LeBlanc E.S., Janowsky J., Chan B.K., and Nelson H.D. Hormone replacement therapy and cognition: systematic review and meta-analysis. JAMA 285 (2001) 1489-1499
    • (2001) JAMA , vol.285 , pp. 1489-1499
    • LeBlanc, E.S.1    Janowsky, J.2    Chan, B.K.3    Nelson, H.D.4
  • 72
    • 26444569232 scopus 로고    scopus 로고
    • Serum cholesterol and risk of Alzheimer disease: a community-based cohort study
    • Li G., Shofer J.B., Kukull W.A., Peskind E.R., Tsuang D.W., Breitner J.C.S., et al. Serum cholesterol and risk of Alzheimer disease: a community-based cohort study. Neurology 65 (2005) 1045-1050
    • (2005) Neurology , vol.65 , pp. 1045-1050
    • Li, G.1    Shofer, J.B.2    Kukull, W.A.3    Peskind, E.R.4    Tsuang, D.W.5    Breitner, J.C.S.6
  • 73
    • 0036725818 scopus 로고    scopus 로고
    • Risk factors for Alzheimer's disease: a prospective analysis from the Canadian Study of Health and Aging
    • Lindsay J., Laurin D., Verreault R., Hebert R., Helliwell B., Hill G.B., et al. Risk factors for Alzheimer's disease: a prospective analysis from the Canadian Study of Health and Aging. Am. J. Epidemiol. 156 (2002) 445-453
    • (2002) Am. J. Epidemiol. , vol.156 , pp. 445-453
    • Lindsay, J.1    Laurin, D.2    Verreault, R.3    Hebert, R.4    Helliwell, B.5    Hill, G.B.6
  • 74
    • 28844488450 scopus 로고    scopus 로고
    • Hormone replacement therapy and cognitive performance in postmenopausal women-a review by cognitive domain
    • Low L.F., and Anstey K.J. Hormone replacement therapy and cognitive performance in postmenopausal women-a review by cognitive domain. Neurosci. Biobehav. Rev. 30 (2006) 66-84
    • (2006) Neurosci. Biobehav. Rev. , vol.30 , pp. 66-84
    • Low, L.F.1    Anstey, K.J.2
  • 76
    • 0036334166 scopus 로고    scopus 로고
    • Caloric intake and the risk of Alzheimer disease
    • Luchsinger J.A., Tang M.X., Shea S., and Mayeux R. Caloric intake and the risk of Alzheimer disease. Arch. Neurol. 59 (2002) 1258-1263
    • (2002) Arch. Neurol. , vol.59 , pp. 1258-1263
    • Luchsinger, J.A.1    Tang, M.X.2    Shea, S.3    Mayeux, R.4
  • 77
    • 0037320324 scopus 로고    scopus 로고
    • Antioxidant vitamin intake and risk of Alzheimer disease
    • Luchsinger J.A., Tang M.X., Shea S., and Mayeux R. Antioxidant vitamin intake and risk of Alzheimer disease. Arch. Neurol. 60 (2003) 203-208
    • (2003) Arch. Neurol. , vol.60 , pp. 203-208
    • Luchsinger, J.A.1    Tang, M.X.2    Shea, S.3    Mayeux, R.4
  • 78
    • 5344256250 scopus 로고    scopus 로고
    • Hyperinsulinemia and risk of Alzheimer disease
    • Luchsinger J.A., Tang M.X., Shea S., and Mayeux R. Hyperinsulinemia and risk of Alzheimer disease. Neurology 63 (2004) 1187-1192
    • (2004) Neurology , vol.63 , pp. 1187-1192
    • Luchsinger, J.A.1    Tang, M.X.2    Shea, S.3    Mayeux, R.4
  • 81
    • 49649122043 scopus 로고    scopus 로고
    • Risk of dementia associated with the ApoE e4 allele and falls causing head injury without explicit traumatic brain injury
    • Luukinen H., Jokelainen J., Kervinen K., Kesäniemi Y.A., Winqvist S., and Hillbom M. Risk of dementia associated with the ApoE e4 allele and falls causing head injury without explicit traumatic brain injury. Acta Neurol. Scand. 118 (2008) 153-158
    • (2008) Acta Neurol. Scand. , vol.118 , pp. 153-158
    • Luukinen, H.1    Jokelainen, J.2    Kervinen, K.3    Kesäniemi, Y.A.4    Winqvist, S.5    Hillbom, M.6
  • 82
    • 13844313428 scopus 로고    scopus 로고
    • Fall-related brain injuries and the risk of dementia in elderly people: a population-based study
    • Luukinen H., Viramo P., Herala M., Kervinen K., Kesaniemi Y.A., Savola O., et al. Fall-related brain injuries and the risk of dementia in elderly people: a population-based study. Eur. J. Neurol. 12 (2005) 86-92
    • (2005) Eur. J. Neurol. , vol.12 , pp. 86-92
    • Luukinen, H.1    Viramo, P.2    Herala, M.3    Kervinen, K.4    Kesaniemi, Y.A.5    Savola, O.6
  • 83
    • 33645742063 scopus 로고    scopus 로고
    • APOE alleles predict the rate of cognitive decline in Alzheimer disease: a nonlinear model
    • Martins C.A.R., Oulhaj A., De Jager C.A., and Williams J.H. APOE alleles predict the rate of cognitive decline in Alzheimer disease: a nonlinear model. Neurology 65 (2005) 1888-1893
    • (2005) Neurology , vol.65 , pp. 1888-1893
    • Martins, C.A.R.1    Oulhaj, A.2    De Jager, C.A.3    Williams, J.H.4
  • 84
    • 37749054064 scopus 로고    scopus 로고
    • Systematic review: blood pressure lowering in patients without prior cerebrovascular disease for prevention of cognitive impairment and dementia
    • McGuinness B., Todd S., Passmore A.P., and Bullock R. Systematic review: blood pressure lowering in patients without prior cerebrovascular disease for prevention of cognitive impairment and dementia. J. Neurol. Neurosurg. Psychiatry 79 (2008) 4-5
    • (2008) J. Neurol. Neurosurg. Psychiatry , vol.79 , pp. 4-5
    • McGuinness, B.1    Todd, S.2    Passmore, A.P.3    Bullock, R.4
  • 85
    • 0032779104 scopus 로고    scopus 로고
    • Head trauma and risk of dementia and Alzheimer's disease: The Rotterdam Study
    • Mehta K.M., Ott A., Kalmijn S., Slooter A.J.C., Van Duijn C.M., Hofman A., et al. Head trauma and risk of dementia and Alzheimer's disease: The Rotterdam Study. Neurology 53 (1999) 1959-1962
    • (1999) Neurology , vol.53 , pp. 1959-1962
    • Mehta, K.M.1    Ott, A.2    Kalmijn, S.3    Slooter, A.J.C.4    Van Duijn, C.M.5    Hofman, A.6
  • 88
    • 0037178579 scopus 로고    scopus 로고
    • Dietary intake of antioxidant nutrients and the risk of incident Alzheimer disease in a biracial community study
    • Morris M.C., Evans D.A., Bienias J.L., Tangney C.C., Bennett D.A., Aggarwal N., et al. Dietary intake of antioxidant nutrients and the risk of incident Alzheimer disease in a biracial community study. JAMA 287 (2002) 3230-3237
    • (2002) JAMA , vol.287 , pp. 3230-3237
    • Morris, M.C.1    Evans, D.A.2    Bienias, J.L.3    Tangney, C.C.4    Bennett, D.A.5    Aggarwal, N.6
  • 92
    • 3042647308 scopus 로고    scopus 로고
    • Estrogen facilitates neurite extension via apolipoprotein E in cultured adult mouse cortical neurons
    • Nathan B.P., Barsukova A.G., Shen F., McAsey M., and Struble R.G. Estrogen facilitates neurite extension via apolipoprotein E in cultured adult mouse cortical neurons. Endocrinology 145 (2004) 3065-3073
    • (2004) Endocrinology , vol.145 , pp. 3065-3073
    • Nathan, B.P.1    Barsukova, A.G.2    Shen, F.3    McAsey, M.4    Struble, R.G.5
  • 93
    • 24344451279 scopus 로고    scopus 로고
    • Dementia and Alzheimer's disease incidence in relationship to cardiovascular disease in the Cardiovascular Health Study Cohort
    • Newman A.B., Fitzpatrick A.L., Lopez O., Jackson S., Lyketsos C., Jagust W., et al. Dementia and Alzheimer's disease incidence in relationship to cardiovascular disease in the Cardiovascular Health Study Cohort. J. Am. Geriatr. Soc. 53 (2005) 1101-1107
    • (2005) J. Am. Geriatr. Soc. , vol.53 , pp. 1101-1107
    • Newman, A.B.1    Fitzpatrick, A.L.2    Lopez, O.3    Jackson, S.4    Lyketsos, C.5    Jagust, W.6
  • 96
    • 0036227542 scopus 로고    scopus 로고
    • Type 2 diabetes, APOE gene, and the risk for dementia and related pathologies: The Honolulu-Asia Aging Study
    • Peila R., Rodriguez B.L., and Launer L.J. Type 2 diabetes, APOE gene, and the risk for dementia and related pathologies: The Honolulu-Asia Aging Study. Diabetes 51 (2002) 1256-1262
    • (2002) Diabetes , vol.51 , pp. 1256-1262
    • Peila, R.1    Rodriguez, B.L.2    Launer, L.J.3
  • 97
    • 46949106968 scopus 로고    scopus 로고
    • Incident dementia and blood pressure lowering in the Hypertension in the Very Elderly Trial cognitive function assessment (HYVET-COG): a double-blind, placebo controlled trial
    • Peters R., Beckett N., Forette F., Tuomilehto J., Clarke R., Ritchie C., et al. Incident dementia and blood pressure lowering in the Hypertension in the Very Elderly Trial cognitive function assessment (HYVET-COG): a double-blind, placebo controlled trial. Lancet Neurol. 7 (2008) 683-689
    • (2008) Lancet Neurol. , vol.7 , pp. 683-689
    • Peters, R.1    Beckett, N.2    Forette, F.3    Tuomilehto, J.4    Clarke, R.5    Ritchie, C.6
  • 98
    • 51749095665 scopus 로고    scopus 로고
    • Alcohol, dementia and cognitive decline in the elderly: a systematic review
    • Peters R., Peters J., Warner J., Beckett N., and Bulpitt C. Alcohol, dementia and cognitive decline in the elderly: a systematic review. Age Ageing 37 (2008) 505-512
    • (2008) Age Ageing , vol.37 , pp. 505-512
    • Peters, R.1    Peters, J.2    Warner, J.3    Beckett, N.4    Bulpitt, C.5
  • 101
    • 0034711173 scopus 로고    scopus 로고
    • Documented head injury in early adulthood and risk of Alzheimer's disease and other dementias
    • Plassman B.L., Havlik R.J., Steffens D.C., Helms M.J., Newman T.N., Drosdick D., et al. Documented head injury in early adulthood and risk of Alzheimer's disease and other dementias. Neurology 55 (2000) 1158-1166
    • (2000) Neurology , vol.55 , pp. 1158-1166
    • Plassman, B.L.1    Havlik, R.J.2    Steffens, D.C.3    Helms, M.J.4    Newman, T.N.5    Drosdick, D.6
  • 102
    • 15744372044 scopus 로고    scopus 로고
    • Physical activity, APOE genotype, and dementia risk: findings from the Cardiovascular Health Cognition Study
    • Podewils L.J., Guallar E., Kuller L.H., Fried L.P., Lopez O.L., Carlson M., et al. Physical activity, APOE genotype, and dementia risk: findings from the Cardiovascular Health Cognition Study. Am. J. Epidemiol. 161 (2005) 639-651
    • (2005) Am. J. Epidemiol. , vol.161 , pp. 639-651
    • Podewils, L.J.1    Guallar, E.2    Kuller, L.H.3    Fried, L.P.4    Lopez, O.L.5    Carlson, M.6
  • 104
    • 38049115446 scopus 로고    scopus 로고
    • Apolipoprotein E represents a potent gene-based therapeutic target for the treatment of sporadic Alzheimer's disease
    • Poirier J. Apolipoprotein E represents a potent gene-based therapeutic target for the treatment of sporadic Alzheimer's disease. Alzheimer's Dement. 4 (2008) S91-S97
    • (2008) Alzheimer's Dement. , vol.4
    • Poirier, J.1
  • 106
    • 0042836671 scopus 로고    scopus 로고
    • Combined effects of APOE genotype, blood pressure, and antihypertensive drug use on incident AD
    • Qiu C., Winblad B., Fastbom J., and Fratiglioni L. Combined effects of APOE genotype, blood pressure, and antihypertensive drug use on incident AD. Neurology 61 (2003) 655-660
    • (2003) Neurology , vol.61 , pp. 655-660
    • Qiu, C.1    Winblad, B.2    Fastbom, J.3    Fratiglioni, L.4
  • 107
    • 22144451172 scopus 로고    scopus 로고
    • The age-dependent relation of blood pressure to cognitive function and dementia
    • Qiu C., Winblad B., and Fratiglioni L. The age-dependent relation of blood pressure to cognitive function and dementia. Lancet Neurol. 4 (2005) 487-499
    • (2005) Lancet Neurol. , vol.4 , pp. 487-499
    • Qiu, C.1    Winblad, B.2    Fratiglioni, L.3
  • 108
    • 64549131779 scopus 로고    scopus 로고
    • Metabolic syndrome and risk for incident Alzheimer's disease or vascular dementia: The Three-City Study
    • Raffaitin C., Gin H., Empana J.-P., Helmer C., Berr C., Tzourio C., et al. Metabolic syndrome and risk for incident Alzheimer's disease or vascular dementia: The Three-City Study. Diabetes Care 32 (2008) 169-174
    • (2008) Diabetes Care , vol.32 , pp. 169-174
    • Raffaitin, C.1    Gin, H.2    Empana, J.-P.3    Helmer, C.4    Berr, C.5    Tzourio, C.6
  • 109
    • 34548399325 scopus 로고    scopus 로고
    • Relation between smoking and risk of dementia and Alzheimer disease: The Rotterdam Study
    • Reitz C., Den Heijer T., Van Duijn C., Hofman A., and Breteler M.M.B. Relation between smoking and risk of dementia and Alzheimer disease: The Rotterdam Study. Neurology 69 (2007) 998-1005
    • (2007) Neurology , vol.69 , pp. 998-1005
    • Reitz, C.1    Den Heijer, T.2    Van Duijn, C.3    Hofman, A.4    Breteler, M.M.B.5
  • 110
    • 33645802650 scopus 로고    scopus 로고
    • Familial Alzheimer disease in Latinos: interaction between APOE, stroke, and estrogen replacement
    • Rippon G.A., Tang M.X., Lee J.H., Lantigua R., Medrano M., and Mayeux R. Familial Alzheimer disease in Latinos: interaction between APOE, stroke, and estrogen replacement. Neurology 66 (2006) 35-40
    • (2006) Neurology , vol.66 , pp. 35-40
    • Rippon, G.A.1    Tang, M.X.2    Lee, J.H.3    Lantigua, R.4    Medrano, M.5    Mayeux, R.6
  • 113
    • 26844483210 scopus 로고    scopus 로고
    • Leisure-time physical activity at midlife and the risk of dementia and Alzheimer's disease
    • Rovio S., Kareholt I., Helkala E.L., Viitanen M., Winblad B., Tuomilehto J., et al. Leisure-time physical activity at midlife and the risk of dementia and Alzheimer's disease. Lancet Neurol. 4 (2005) 705-711
    • (2005) Lancet Neurol. , vol.4 , pp. 705-711
    • Rovio, S.1    Kareholt, I.2    Helkala, E.L.3    Viitanen, M.4    Winblad, B.5    Tuomilehto, J.6
  • 116
    • 0347985261 scopus 로고    scopus 로고
    • A comparison of a food frequency questionnaire with a 24-hour recall for use in an epidemiological cohort study: results from the biomarker-based Observing Protein and Energy Nutrition (OPEN) study
    • Schatzkin A., Kipnis V., Carroll R.J., Midthune D., Subar A.F., Bingham S., et al. A comparison of a food frequency questionnaire with a 24-hour recall for use in an epidemiological cohort study: results from the biomarker-based Observing Protein and Energy Nutrition (OPEN) study. Int. J. Epidemiol. 32 (2003) 1054-1062
    • (2003) Int. J. Epidemiol. , vol.32 , pp. 1054-1062
    • Schatzkin, A.1    Kipnis, V.2    Carroll, R.J.3    Midthune, D.4    Subar, A.F.5    Bingham, S.6
  • 117
    • 0031971434 scopus 로고    scopus 로고
    • A population study of apoE genotype at the age of 85: Relation to dementia, cerebrovascular disease, and mortality
    • Skoog I., Hesse C., Aevarsson O., Landahl S., Wahlstrom J., Fredman P., et al. A population study of apoE genotype at the age of 85: Relation to dementia, cerebrovascular disease, and mortality. J. Neurol. Neurosurg. Psychiatry 64 (1998) 37-43
    • (1998) J. Neurol. Neurosurg. Psychiatry , vol.64 , pp. 37-43
    • Skoog, I.1    Hesse, C.2    Aevarsson, O.3    Landahl, S.4    Wahlstrom, J.5    Fredman, P.6
  • 120
    • 12144268588 scopus 로고    scopus 로고
    • A 32-year prospective study of change in body weight and incident dementia: the Honolulu-Asia Aging Study
    • Stewart R., Masaki K., Xue Q.L., Peila R., Petrovitch H., White L.R., et al. A 32-year prospective study of change in body weight and incident dementia: the Honolulu-Asia Aging Study. Arch. Neurol. 62 (2005) 55-60
    • (2005) Arch. Neurol. , vol.62 , pp. 55-60
    • Stewart, R.1    Masaki, K.2    Xue, Q.L.3    Peila, R.4    Petrovitch, H.5    White, L.R.6
  • 121
    • 33845644951 scopus 로고    scopus 로고
    • Increased risk of dementia following mild head injury for carriers but not for non-carriers of the APOE e5 allele
    • Sundstrom A., Nilsson L.-G., Cruts M., Adolfsson R., Van Broeckhoven C., and Nyberg L. Increased risk of dementia following mild head injury for carriers but not for non-carriers of the APOE e5 allele. Int. Psychogeriatr. 19 (2007) 159-165
    • (2007) Int. Psychogeriatr. , vol.19 , pp. 159-165
    • Sundstrom, A.1    Nilsson, L.-G.2    Cruts, M.3    Adolfsson, R.4    Van Broeckhoven, C.5    Nyberg, L.6
  • 122
  • 125
    • 0030591669 scopus 로고    scopus 로고
    • Effect of oestrogen during menopause on risk and age at onset of Alzheimer's disease
    • Tang M.X., Jacobs D., Stern Y., Marder K., Schofield P., Gurland B., et al. Effect of oestrogen during menopause on risk and age at onset of Alzheimer's disease. Lancet 348 (1996) 429-432
    • (1996) Lancet , vol.348 , pp. 429-432
    • Tang, M.X.1    Jacobs, D.2    Stern, Y.3    Marder, K.4    Schofield, P.5    Gurland, B.6
  • 126
    • 8044235632 scopus 로고    scopus 로고
    • Effect of age, ethnicity, and head injury on the association between APOE genotypes and Alzheimer's disease
    • Tang M.X., Maestre G., Tsai W.Y., Liu X.H., Feng L., Chung W.Y., et al. Effect of age, ethnicity, and head injury on the association between APOE genotypes and Alzheimer's disease. Ann. N. Y. Acad. Sci. 802 (1996) 6-15
    • (1996) Ann. N. Y. Acad. Sci. , vol.802 , pp. 6-15
    • Tang, M.X.1    Maestre, G.2    Tsai, W.Y.3    Liu, X.H.4    Feng, L.5    Chung, W.Y.6
  • 128
    • 0028986481 scopus 로고
    • Apolipoprotein E genotype and association between smoking and early onset Alzheimer's disease
    • Van Duijn C.M., Havekes L.M., Van Broeckhoven C., De Knijff P., and Hofman A. Apolipoprotein E genotype and association between smoking and early onset Alzheimer's disease. Br. Med. J. 310 (1995) 627-631
    • (1995) Br. Med. J. , vol.310 , pp. 627-631
    • Van Duijn, C.M.1    Havekes, L.M.2    Van Broeckhoven, C.3    De Knijff, P.4    Hofman, A.5
  • 130
    • 0035852932 scopus 로고    scopus 로고
    • APOE-epsilon4 is associated with weight loss in women with AD: a population-based study
    • Vanhanen M., Kivipelto M., Koivisto K., Kuusisto J., Mykkanen L., Helkala E.L., et al. APOE-epsilon4 is associated with weight loss in women with AD: a population-based study. Neurology 56 (2001) 655-659
    • (2001) Neurology , vol.56 , pp. 655-659
    • Vanhanen, M.1    Kivipelto, M.2    Koivisto, K.3    Kuusisto, J.4    Mykkanen, L.5    Helkala, E.L.6
  • 131
    • 33847061307 scopus 로고    scopus 로고
    • The effect of borderline diabetes on the risk of dementia and Alzheimer's disease
    • Xu W.L., Qiu C., Winblad B., and Fratiglioni L. The effect of borderline diabetes on the risk of dementia and Alzheimer's disease. Diabetes 56 (2007) 211-216
    • (2007) Diabetes , vol.56 , pp. 211-216
    • Xu, W.L.1    Qiu, C.2    Winblad, B.3    Fratiglioni, L.4
  • 132
    • 5344237420 scopus 로고    scopus 로고
    • Diabetes mellitus and risk of dementia in the Kungsholmen project: a 6-year follow-up study
    • Xu W.L., Qiu C.X., Wahlin A., Winblad B., and Fratiglioni L. Diabetes mellitus and risk of dementia in the Kungsholmen project: a 6-year follow-up study. Neurology 63 (2004) 1181-1186
    • (2004) Neurology , vol.63 , pp. 1181-1186
    • Xu, W.L.1    Qiu, C.X.2    Wahlin, A.3    Winblad, B.4    Fratiglioni, L.5
  • 133
    • 14544306103 scopus 로고    scopus 로고
    • Nonsteroidal anti-inflammatory drug use and Alzheimer's disease risk: The MIRAGE study
    • Yip A.G., Green R.C., Huyck M., Cupples L.A., and Farrer L.A. Nonsteroidal anti-inflammatory drug use and Alzheimer's disease risk: The MIRAGE study. BMC Geriatr. (2005) 5
    • (2005) BMC Geriatr. , pp. 5
    • Yip, A.G.1    Green, R.C.2    Huyck, M.3    Cupples, L.A.4    Farrer, L.A.5
  • 134
    • 0037032401 scopus 로고    scopus 로고
    • Hormone replacement therapy and incidence of Alzheimer disease in older women: The Cache County Study
    • Zandi P.P., Carlson M.C., Plassman B.L., and Welsh-Bohmer K.A. Hormone replacement therapy and incidence of Alzheimer disease in older women: The Cache County Study. JAMA 288 (2002) 2123
    • (2002) JAMA , vol.288 , pp. 2123
    • Zandi, P.P.1    Carlson, M.C.2    Plassman, B.L.3    Welsh-Bohmer, K.A.4
  • 135
    • 0034643841 scopus 로고    scopus 로고
    • Incidence of stroke in relation to cognitive function and dementia in the Kungsholmen Project
    • Zhu L., Fratiglioni L., Guo Z., Winblad B., and Viitanen M. Incidence of stroke in relation to cognitive function and dementia in the Kungsholmen Project. Neurology 54 (2000) 2103-2107
    • (2000) Neurology , vol.54 , pp. 2103-2107
    • Zhu, L.1    Fratiglioni, L.2    Guo, Z.3    Winblad, B.4    Viitanen, M.5


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