FIP-fve stimulates interferon-gamma production via modulation of calcium release and PKC-α activation

Journal of Agricultural and Food Chemistry

Volumn 57, Issue 22, 2009, Pages 11008-11013

  Ou, Chu Chyn ^a,c,e   Hsiao, Yi Min ^b   Wu, Wen Jun ^d   Tasy, Gregory J ^d   Ko, Jiunn Liang ^c,d   Lin, Meei Yn ^e  

^a Chung Shan Medital University   (Taiwan)

^b CENTRAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

^c CHUNG SHAN MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^d CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^e NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

Author keywords

Calcium; FIP; IFN ; PBMC; PKC

Indexed keywords

CALCIUM; CHELATING AGENT; FIP FVE PROTEIN, FLAMMULINA VELUTIPES; FIP-FVE PROTEIN, FLAMMULINA VELUTIPES; FUNGAL PROTEIN; GAMMA INTERFERON; MESSENGER RNA; PROTEIN KINASE C ALPHA; PROTEIN KINASE INHIBITOR;

ARTICLE; BIOSYNTHESIS; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; ENZYME ACTIVATION; ENZYMOLOGY; FLAMMULINA; GENETICS; HUMAN; IMMUNOLOGY; METABOLISM; MONONUCLEAR CELL; TH1 CELL;

CALCIUM; CHELATING AGENTS; ENZYME ACTIVATION; FLAMMULINA; FUNGAL PROTEINS; HUMANS; INTERFERON-GAMMA; LEUKOCYTES, MONONUCLEAR; PROTEIN KINASE C-ALPHA; PROTEIN KINASE INHIBITORS; RNA, MESSENGER; TH1 CELLS;

FLAMMULINA; FLAMMULINA VELUTIPES;

EID: 72449167453     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf902725s     Document Type: Article

References (44)

1. Ko, J. L.; Hsu, C. I.; Lin, R. H.; Kao, C. L.; Lin, J. Y. A new fungal immunomodulatory protein, FIP-fve isolated from the edible mushroom, Flammulina velutipes and its complete amino acid sequence. Eur. J. Biochem. 1995, 225, 244-249.
2. Wang, P. H.; Hsu, C. I.; Tang, S. C.; Huang, Y. L.; Lin, J. Y.; Ko, J. L. Fungal immunomodulatory protein from Flammulina velutipes induces interferon-gamma production through p38 mitogen-activated protein kinase signaling pathway, J. Agric. Food Chem. 2004, 52, 2721-2725.
3. Teixeira, L. K.; Fonseca, B. P.; Vieira-de-Abreu, A.; Barboza, B. A.; Robbs, B. K.; Bozza, P. T.; Viola, J. P. IFN-gamma production by CD8+ T cells depends on NFAT1 transcription factor and regulates Th differentiation, J. Immunol. 2005, 175, 5931-5939.
4. Boehm, U.; Klamp, T.; Groot, M.; Howard, J. C. Cellular responses to interferon-gamma. Annu. Rev. Immunol 1997, 15, 749-795.
5. (5) Hsieh, K. Y.; Hsu, C. I.; Lin, J. Y.; Tsai, C. C.; Lin, R. H. Oral administration of an edible-mushroom-derived protein inhibits the development of food-allergic reactions in mice. Clin. Exp. Allergy 2003, 33, 1595-1602. (Pubitemid 37421640)
6. Hsiao, Y. M.; Huang, Y. L.; Tang, S. C.; Shieh, G. J.; Lai, J. Y.; Wang, P. H.; Ying, T. H.; Ko, J. L. Effect of a fungal immunomodulatory protein from Ganoderma tsugae on cell cycle and interferongamma production through phosphatidylinositol 3-kinase signal pathway. Process Biochem. 2008, 43,423-430.
7. Lee, Y. J.; Shim, J. W.; Park, Y. H.; Lee, H. Y.; Kim, S. D.; Choi, Y. W.; Bae, Y. S. Identification of a novel compound that stimulates intracellular calcium increase and CXCL8 production in human neutrophils from Schisandra chinensis. Biochem. Biophys. Res. Commun. 2009, 379, 928-932.
8. Hsu, H. Y.; Hua, K. F.; Wu, W. C.; Hsu, J.; Weng, S. T.; Lin, T. L.; Liu, C. Y.; Hseu, R. S.; Huang, C. T. Reishi immuno-modulation protein induces interleukin-2 expression via protein kinase-dependent signaling pathways within human T cells. J. Call. Physiol. 2008, 215, 15-26.
9. Berridge, M. J.; Bootman, M. D.; Roderick, H. L. Calcium signalling: dynamics, homeostasis and remodelling, Nat. Rev. Mol. Cell Biol. 2003, 4, 517-529.
10. Berridge, M. J.; Lipp, P.; Bootman, M. D. The versatility and universality of calcium signalling, Nat. Rev. Mol. Cell Biol 2000, 1,11-21.
11. Rao, A.; Luo, C.; Hogan, P. G. Transcription factors of the NFAT family: regulation and function. Annu. Rev. Immunol. 1997, 15,707-747.
12. (12) Cantreil, D. T cell antigen receptor signal transduction, pathways. Annu. Rev. Immunol 1996, 14, 259-274. (Pubitemid 26130185)
13. (13) Szabo, S. J.; Sullivan, B. M.; Peng, S. L.; Glimcher, L. H. Molecular mechanisms regulating Th1 immune responses. Annu. Rev. Immunol. 2003, 21,713-758. (Pubitemid 37174546)
14. (14) Favero, J.; Lafont, V. Effector pathways regulating T cell activation. Biochem. Pharmacol. 1998, 56,1539-1547. (Pubitemid 28561473)
15. Aires, V.; Hichami, A.; Filomenko, R.; Ple, A.; Rebe, C.; Bettaieb, A.; Khan, N. A. Docosahexaenoic acid induces increases in [Ca2+]i via inositol 1,4,5-triphosphate production and activates protein kinase C gamma and -delta via phosphatidylserine binding site: implication in apoptosis in U937 cells. Mal. Pharmacol. 2007, 72, 1545-1556.
16. Tan, S. L.; Parker, P. J. Emerging and diverse roles of protein kinase C in immune cell signalling, Biochem. J. 2003, 376, 545-552.
17. (17) Chen, Y. C.; Tsai, W. J.; Wu, M. H.; Lin, L. C.; Kuo, Y. C. Suberosin inhibits proliferation of human peripheral blood mononuclear cells through the modulation of the transcription factors NF-AT and NFkappaB. Br. J. Pharmacol. 2007, 150, 298-312. (Pubitemid 46221039)
18. Yoshimaru, T.; Suzuki, Y.; Inoue, T.; Ra, C. L-type Ca2+ channels in mast cells: activation by membrane depolarization and distinct roles in regulating mediator release from store-operated Ca2+ channels. Mol. Immunol. 2009, 46,1267-1277.
19. (19) Panichi, V.; De Pietro, S.; Andreini, B.; Migliori, M.; Taccola, D.; Giovannini, L.; Tetta, C.; Palla, R. Calcitriol modulates in vivo and in vitro cytokine production: a role for intracellular calcium. Kidney Int. 1998, 54, 1463-1469. (Pubitemid 28502888)
20. Grynkiewicz, G.; Poenie, M.; Tsien, R. Y. A new generation of Ca2+ indicators with greatly improved fluorescence properties. J. Biol. Chem. 1985, 260, 3440-3450.
21. Merritt, J. E.; McCarthy, S. A.; Davies, M. P.; Moores, K. E. Use of fluo-3 to measure cytosolic Ca2+ in platelets and neutrophils. Loading cells with the dye, calibration of traces, measurements in the presence of plasma, and buffering of cytosolic Ca2+. Biochem. J. 1990, 269, 513-519.
22. Buggins, A. G.; Milojkovic, D.; Arno, M. J.; Lea, N. C.; Mufti, G. J.; Thomas, N. S.; Hirst, W. J. Microenvironment produced by acute myeloid leukemia cells prevents T cell activation and proliferation by inhibition of NF-kappaB, c-Myc, and pRb pathways. J. Immunol. 2001, 167, 6021-6030.
23. Berridge, M. J. Inositol trisphosphate and calcium signalling. Nature 1993, 567, 315-325.
24. Dadsetan, S.; Zakharova, L.; Molinski, T. F.; Fomina, A. F. Storeoperated Ca2+ influx causes Ca2+ release from, the intracellular Ca2+ channels that is required for T cell activation. J. Biol. Chem. 2008, 283, 12512-12519.
25. (25) Hosoi, E.; Nishizaki, C.; Gallagher, K. L.; Wyre, H. W.; Matsuo, Y.; Sci, Y. Expression of the ryanodine receptor isoforms in immune cells, J. Immunol. 2001, 167, 4887-4894. (Pubitemid 33009717)
26. Galione, A.; Churchill, G. C. Interactions between calcium release pathways: multiple messengers and multiple stores. Cell Calcium 2002, 32, 343-354.
27. (27) Manicassamy, S.; Sadim, M.; Ye, R. D.; Sun, Z. Differential roles of PKC-theta in the regulation of intracellular calcium concentration in primary T cells. J. Mol Biol. 2006, 355, 347-359. (Pubitemid 41785743)
28. Chen, Y. L.; Chen, Y. S.; Lin, H. H.; Chan, C. W.; Chen, S. C.; Chen, C. H. Immunostimulatory flagellin from Burkholderia pseudomallei effects on an increase in the intracellular calcium concentration and up-regulation of TNF-alpha by mononuclear cells. Microbiol. Immnol. 2001, 51, 81-86.
29. (29) Petrov, V.; Lijnen, P. Inhibition of proliferation of human peripheral blood mononuclear cells by calcium antagonists. Role of interleukin2. Methods Find. Exp. Clin. Pharmacol. 2000, 22, 19-23. (Pubitemid 30176411)
30. (30) Lijnen, P.; Petrov, V. Proliferation of human peripheral blood mononuclear cells during calcium entry blockade. Role of protein kinase C. Methods Find. Exp. Clin. Pharmacol. 1999, 21, 253-259. (Pubitemid 29283879)
31. Monteith, G. R.; McAndrew, D.; Faddy, H. M.; Roberts-Thomson, S. J. Calcium and cancer: targeting Ca2+ transport. Nat. Rev. Cancer 2001, 7, 519-530.
32. Park, J. H.; Lee, M. Y.; Heo, J. S.; Han, H. J. A potential role of connexin 43 in epidermal growth factor-induced proliferation of mouse embryonic stem cells: involvement of Ca2+/PKC, p44/42 and p38 MAPKs pathways. Cell Proliferation 2008, 41, 786-802.
33. Cook, S. J.; Lockyer, P. J. Recent advances in Ca(2+)-dependent Ras regulation and cell proliferation. Cell Calcium 2006, 39, 101-112.
34. Jang, M. K.; Goo, Y. H.; Sohn, Y. C.; Kim, Y. S.; Lee, S. K.; Kang, H.; Cheong, J.; Lee, J. W. Ca2+/calmodulin-dependent protein kinase IV stimulates nuclear factor-kappa B transactivation via phosphorylation of the p65 subunit. J. Boil. Chem. 2001, 276, 20005-20010.
35. (35) Crabtree, G. R. Contingent genetic regulatory events in T lymphocyte activation, Science 1989, 243, 355-361. (Pubitemid 19047509)
36. Guo, L.; Urban, J. F.; Zhu, J.; Paul, W. E. Elevating calcium in Th2 cells activates multiple pathways to induce I.L-4 transcription and mRNA stabilization. J. Immunol 2008, 181, 3984-3993.
37. Nishizuka, Y. Protein kinase C and lipid signaling for sustained cellular responses. FASEB J. 1995, 9, 484-496.
38. Dempsey, E. C.; Newton, A. C.; Mochly-Rosen, D.; Fields, A. P.; Reyland, M. E.; Insel, P. A.; Messing, R. O. Protein kinase C isozymes and the regulation of diverse cell responses. Am. J. Physiol. 2000, 279, L429-438.
39. Liu, C. P.; Kuo, Y. C.; Shen, C. C.; Wu, M. H.; Liao, J. F.; Lin, Y. L.; Chen, C. F.; Tsai, W. J. (S)-armepavine inhibits human peripheral blood mononuclear cell activation by regulating Itk and PLCgamma activation in a PI-3K-dependent manner. J. Leukocyte Biol. 2007, 81, 1276-1286.
40. Newton, A. C. Protein kinase C: structure, function, and regulation. J. Biol. Chem. 1995, 270, 28495-28498.
41. Wu, J.; Xiao,X.; Jia, H.; Chen, J.; Zhu, Y.; Zhao, P.; Lin, H.; Huang, W. Dynamic distribution and expression in vivo of the human interferon gamma gene delivered by adenoviral vector. BMC Cancer 2009, 9, 55.
42. Younes, H. M.; Amsden, B. G. Interferon-gamma therapy: evaluation of routes of administration and delivery systems. J. Pharm. Sci.. 2002, 91, 2-17.
43. Ko, J. L.; Lin, S. J.; Hsu, C. I.; Kao, C. L.; Lin, J. Y. Molecular cloning and expression of a fungal immunomodulatory protein, FIPfve, from Flammulina velutipes. J. Formosan Med. Assoc. 1997, 96, 517-524.
44. (44) Tong, M. H.; Chien, P. J.; Chang, H. H.; Tsai, M. J.; Sheu, F. High processing tolerances of immunomodulatory proteins in Enoki and Reishi mushrooms. J. Agric. Food Chem. 2008, 56, 3160-3166. (Pubitemid 351746042)