Suberosin inhibits proliferation of human peripheral blood mononuclear cells through the modulation of the transcription factors NF-AT and NF-κB

British Journal of Pharmacology

Volumn 150, Issue 3, 2007, Pages 298-312

  Chen, Y C ^a   Tsai, W J ^b,c   Wu, M H ^a   Lin, L C ^b   Kuo, Y C ^d  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b NATIONAL RESEARCH INSTITUTE OF CHINESE MEDICINE   (Taiwan)

^c National Tai Tung University   (Taiwan)

^d FU JEN CATHOLIC UNIVERSITY   (Taiwan)

Author keywords

Ca 2+ i; ERK; NF B; NF AT; PBMC; Proliferation; Suberosin

Indexed keywords

CALCIUM ION; CELL DNA; CYCLIN A; CYCLIN B; CYCLIN D3; CYCLIN E; CYTOKINE; GAMMA INTERFERON; HERBACEOUS AGENT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 2; MITOGEN ACTIVATED PROTEIN KINASE; PHYTOHEMAGGLUTININ; PLUMBAGO ZEYLANICA EXTRACT; SUBEROSIN; THYMIDINE; TRANSCRIPTION FACTOR NFAT; TRITIUM; UNCLASSIFIED DRUG;

ADULT; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CALCIUM CELL LEVEL; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL CYCLE PROGRESSION; CELL CYCLE S PHASE; CELL NUCLEUS; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CYTOKINE PRODUCTION; DNA BINDING; GEL MOBILITY SHIFT ASSAY; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOCYTOCHEMISTRY; IMMUNOMODULATION; MALE; MEDICINAL PLANT; MITOSIS INHIBITION; NORMAL HUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PHARMACOLOGICAL BLOCKING; PLUMBAGO ZEYLANICA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANTI-INFLAMMATORY AGENTS; CELL CYCLE; CELL PROLIFERATION; COUMARINS; GENE EXPRESSION; HUMANS; LEUKOCYTES, MONONUCLEAR; NF-KAPPA B; NFATC TRANSCRIPTION FACTORS; PLANT EXTRACTS; PLUMBAGINACEAE; POLYMERASE CHAIN REACTION;

EID: 33846889731     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/sj.bjp.0706987     Document Type: Article

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