A potential role of connexin 43 in epidermal growth factor-induced proliferation of mouse embryonic stem cells: Involvement of Ca2+/PKC, p44/42 and p38 MAPKs pathways

Cell Proliferation

Volumn 41, Issue 5, 2008, Pages 786-802

  Park, J H ^a   Lee, M Y ^a   Heo, J S ^a   Han, H J ^a  

^a Chonnam National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

18ALPHA GLYCYRRHETINIC ACID; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; BISINDOLYLMALEIMIDE; CALCIUM; CONNEXIN 43; CYCLIN D1; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE INHIBITOR 1B; CYCLIN E; DEOXYGLUCOSE; EGTAZIC ACID; EPIDERMAL GROWTH FACTOR; GLUCOSE TRANSPORTER 1; HERBIMYCIN A; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; MYC PROTEIN; P21 ACTIVATED KINASE; PROTEIN C FOS; PROTEIN C JUN; PROTEIN KINASE C; PROTEIN P42; STAUROSPORINE; THYMIDINE;

ANIMAL CELL; ARTICLE; CALCIUM TRANSPORT; CELL COUNT; CELL CYCLE REGULATION; CELL PROLIFERATION; CONTROLLED STUDY; EMBRYO CELL; GENETIC TRANSFECTION; MOUSE; NONHUMAN; PROTEIN EXPRESSION; STEM CELL;

ANIMALS; CALCIUM; CALCIUM SIGNALING; CELL CYCLE PROTEINS; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; CONNEXIN 43; EMBRYONIC STEM CELLS; ENZYME INHIBITORS; EPIDERMAL GROWTH FACTOR; GAP JUNCTIONS; GENE EXPRESSION REGULATION; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 3; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTEIN KINASE C; PROTO-ONCOGENE PROTEINS C-FOS; PROTO-ONCOGENE PROTEINS C-JUN; PROTO-ONCOGENE PROTEINS C-MYC; RNA, MESSENGER;

EID: 51649121377     PISSN: 09607722     EISSN: 13652184     Source Type: Journal    
DOI: 10.1111/j.1365-2184.2008.00552.x     Document Type: Article

References (61)

1. Adams PD, Parker PJ (1991) TPA-induced activation of MAP kinase. FEBS Lett. 290, 77 82.
2. Bani-Yaghoub M, Bechberger JF, Naus CC (1997) Reduction of connexin43 expression and dye-coupling during neuronal differentiation of human NTera2/clone D1 cells. J. Neurosci. Res. 49, 19 31.
3. Bani-Yaghoub M, Bechberger JF, Underhill TM, Naus CC (1999) The effects of gap junction blockage on neuronal differentiation of human NTera2/clone D1 cells. Exp. Neurol. 156, 16 32.
4. Belliveau DJ, Bechberger JF, Rogers KA, Naus CC (1997) Differential expression of gap junctions in neurons and astrocytes derived from P19 embryonal carcinoma cells. Dev. Genet. 21, 187 200.
5. Bevilacqua A, Loch-Caruso R, Erickson RP (1989) Abnormal development and dye coupling produced by antisense RNA to gap junction protein in mouse preimplantaion embryos. Proc. Natl. Acad. Sci. USA 86, 5444 5448.
6. Birnbaum MJ, Haspel HC, Rosen OM (1987) Transformation of rat fibroblasts by FSV rapidly increases glucose transporter gene transcription. Science 235, 1495 1498.
7. Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248 254.
8. Brett CM, Washington CB, Ott RJ, Gutierrez MM, Giacomini KM (1993) Interaction of nucleoside analogues with the sodium-nucleoside transport system in brush border membrane vesicles from human kidney. Pharm. Res. 10, 423 426.
9. Camoron SJ, Malik S, Akaike M, Lerner-Marmarosh N, Yan C, Lee JD, Abe J, Yang J (2003) Regulation of epidermal growth factor-induce connexin 43 gap junction communication by big mitogen-activated protein kinase 1/ERK5 but not ERK1/2 kinase activation. J. Biol. Chem. 278, 18682 18688.
10. 2+ transport in Caco-2 cell cultures. Am. J. Phyisol. 274, G389 G396.
11. Cogle CR, Guthrie SM, Sanders RC, Allen WL, Scott EW, Petersen BE (2003) An overview of stem cell research and regulatory issues. Mayo Clin. Proc. 78, 993 1003.
12. Cooke PS, Hess RA, Kirby JD, Bunick D, Hardy MP (1994) Neonatal propylthiouracil treatment as a model system for studying factors controlling testis growth and sperm production. In : Bartke A, ed. Function of Somatic Cells in the Testis, pp. 400 407. New York : Springer-Verlag.
13. Croniger C, Leahy P, Reshef L, Hanson RW (1998) C/EBP and the control of phosphoenolpyruvate carboxykinase gene transcription in the liver. J. Biol. Chem. 273, 31629 31632.
14. De Maio A, Vega VL, Contreras JE (2002) Gap junctions, homeostasis, and injury. J. Cell. Physiol. 191, 269 282.
15. Eilers M, Schirm S, Bishop JM (1991) The Myc protein activates transcription of the α-prothymosin gene. EMBO J. 10, 133 141.
16. El-Fouly MH, Trosko JE, Chang CC (1987) Scrape-loading and dye transfer: a rapid and simple technique to study gap junctional intercellular communication. Exp. Cell Res. 168, 422 430.
17. Evans MJ, Kaufman MH (1981) Establishment in culture of pluripotential cells from mouse embryos. Nature 292, 154 156.
18. Furudoi A, Tanaka S, Haruma K, Yoshihara M, Sumii K, Kajiyama G, Shimamoto F (2001) Clinical significance of human erythrocyte glucose transporter 1 expression at the deepset invasive site of advanced colorectal carcinoma. Oncology 60, 162 169.
19. Gilleron J, Nebout M, Scarabelli L, Senegas-Balas F, Palmero S, Segretain D, Pointis G (2006) A potential novel mechanism involving connexin 43 gap junction for control of sertoli cell proliferation by thyroid hormones. J. Cell. Physiol. 209, 153 161.
20. Godwin AJ, Green LM, Walsh MP, McDonald JR, Walsh DA, Fletcher WH (1993) In situ regulation of cell-cell communication by the cAMP-dependent protein kinase and protein kinase C. Mol. Cell. Biochem. 127/128, 293 307.
21. Guthrie SC, Gilula NB (1989) Gap junctional communication and development. Trends Neurosci. 12, 12 16.
22. Glabowski W, Kurzawa R, Wiszniewska B, Baczkowski T, Marchlewicz M, Brelik P (2005) Growth factors effects on preimplantation development of mouse embryos exposed to tumor necrosis factor alpha. Reprod. Biol. 5, 83 99.
23. 2+/protein kinase C and EGF receptor as well as gli1 activation. Stem Cells 25, 3069 3080.
24. Kanemitsu MY, Lau AF (1993) Epidermal growth factor stimulates the distribution of gap junctional communication and connexin 43 phosphorylation independent of 12-O-tetradecanoylphorbol 13-acetate sensitive protein kinase C: the possible involvement of mitogen activated protein kinase. Mol. Biol. Cell 4, 837 848.
25. Lampe PD, Lau AF (2004) The effects of connexin phosphorylation on gap junctional communication. Int. J. Biochem. Cell Biol. 36, 1171 1186.
26. Lange C, Bassler P, Lioznov MV, Bruns H, Kluth D, Zander AR, Fiegel HC (2005) Hepatocytic gene expression in cultured rat mesenchymal stem cells. Transplant. Proc. 37, 276 279.
27. Le AC, Musil LS (1998) Normal differentiation of cultured lens cells after inhibition of gap junction-mediated intercellular communication. Dev. Biol. 204, 80 96.
28. Lee S, Gilula NB, Warner AE (1987) Gap junctional communication and compaction during preimplantation stages of mouse development. Cell 51, 851 860.
29. 2+/PKC, MAPKs and HIF-1α. Cell. Physiol. Biochem. 19, 269 282.
30. Lee SH, Lee MY, Han HJ (2008) Short time hypoxia increases mouse embryonic stem cells proliferation through cooperation of arachidonic acid and PI3K/Akt signal pathways. Cell Prolif. 41, 230 247.
31. Loewenstein WR (1979) Junctional intercellular communication and the control of growth. Biochim. Biophys. Acta 560, 1 65.
32. Loewenstein WR, Rose B (1992) The cell-cell channel in the control of growth. Semin. Cell Biol. 3, 59 79.
33. Mackman N, Brand K, Edgington TS (1991) Lipopolysaccharide-mediated transcriptional activation of the human tissue factor gene in THP-1 monocytic cells requires both activator protein 1 and nuclear factor κB binding sites. J. Exp. Med. 174, 1517 1526.
34. Madhukar BV, Oh SY, Chang CC, Wade M, Trosko JE (1989) Altered regulation of intercellular communication by epidermal growth factor, transforming growth factor-β and peptide hormones in normal human keratinocytes. Carcinogenesis 10, 13 20.
35. Maldonado PE, Rose B, Loewenstein WR (1988) Growth factors modulate junctional cell-to-cell communication. J. Membr. Biol. 106, 203 210.
36. 1 phase of the cell cycle. Cell 65, 701 713.
37. Moorby CD, Stoker M, Gherardi E (1995) HGF/SF inhibits junctional communication. Exp. Cell Res. 219, 657 663.
38. Murakami Y, Satake M, Yamaguchi-Iwai Y, Sakai M, Muramatsu M, Ito Y (1991) The nuclear protooncogenes c-jun and c-fos as regulators of DNA replication. Proc. Natl. Acad. Sci. USA 88, 3947 3951.
39. Nishi M, Kumar NM, Gilula NB (1991) Developmental regulation of gap junction gene expression during mouse embryonic development. Dev. Biol. 146, 117 130.
40. Ogawa J, Inoue H, Koide S (1997) Glucose-transporter-type-I-gene amplification correlates with sialyl-Lewis-X synthesis and proliferation in lung cancer. Int. J. Cancer 74, 189 192.
41. Oyamada Y, Komatsu K, Kimura H, Mori M, Oyamada M (1996) Differential regulation of gap junction protein (connexin) genes during cardiomyocytic differentiation of mouse embryonic stem cells in vitro. Exp. Cell Res. 229, 318 326.
42. Petrich BG, Gong X, Lerner DL, Wang X, Brown JH, Saffitz JE, Wang Y (2002) c-Jun N-terminal kinase activation mediates downregulation of connexin43 in cardiomyocytes. Circ. Res. 91, 640 647.
43. Pitman M, Emery B, Binder M, Wang S, Butzkueven H, Kilpatrick TJ (2004) LIF receptor signaling modulates neural stem cell renewal. Mol. Cell. Neurosci. 27, 255 266.
44. Polontchouk L, Ebelt B, Jackels M, Dhein S (2002) Chronic effects of endothelin 1 and angiotensin II on gap junctions and intercellular communication in cardiac cells. FASEB J. 16, 87 89.
45. Postma FR, Hengeveld T, Alblas J, Giepmans BN, Zondag GC, Jalink K, Moonlenaar WH (1998) Acute loss of cell-cell communication caused by G protein-coupled receptors: a critical role for c-Src. J. Cell Biol. 140, 1199 1209.
46. Prall OW, Sarcevic B, Musgrove EA, Watts CKW, Sutherland RL (1997) Estrogen-induced activation of Cdk4 and Cdk2 during G1-S phase progression is accompanied by increased cyclin D1 expression and decreased cylcin-dependent kinase inhibitor association with cylcin E-Cdk2. J. Biol. Chem. 272, 10882 10894.
47. Ran W, Dean M, Levine RA, Henkle C, Campisi J (1986) Induction of c-fos and c-myc mRNA by epidermal growth factor or calcium ionophore is cAMP dependent. Proc. Natl. Acad. Sci. USA 83, 8216 8220.
48. Ren P, Mehta PP, Ruch RJ (1998) Inhibition of gap junctional intercellular communication by tumor promoters in connexin43 and connexin43-expressing liver cells: cell specificity and role of protein kinase C. Carcinogenesis 19, 169 175.
49. Ruch RJ (1994) The role of gap junctional intercellular communication in neoplasia. Ann. Clin. Lab. Sci. 24, 216 231.
50. Schonwasser DC, Marais RM, Marshall CJ, Parker PJ (1998) Activation of the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway by conventional, novel and atypical protein kinase C isotypes. Mol. Cell Biol. 18, 790 798.
51. Smith AG, Hooper ML (1987) Buffalo rat liver cells produce a diffusible activity which inhibits the differentiation of murine embryonal carcinoma and embryonic stem cells. Dev. Biol. 121, 1 9.
52. Stock A, Sies H, Stahl W (1998) Enhancement of gap junctional communication and connexin43 expression by thyroid hormones. Biochem. Pharmacol. 55, 475 479.
53. Tabernero A, Sanchez-Alvarez R, Medina JM (2006) Increased levels of cyclins D1 and D3 after inhibition of gap junctional communication in astrocytes. J. Neurochem. 96, 973 982.
54. Todorova MG, Soria B, Quesada I (2008) Gap junctional intercellular communication is required to maintain embryonic stem cells in a non-differentiated and proliferative state. J. Cell. Physiol. 214, 354 362.
55. Tropepe V, Sibilia M, Ciruna BG, Rossant J, Wagner EF, van der Kooy D (1999) Distinct neural stem cells proliferate in response to EGF and FGF in the developing mouse telencephalon. Dev. Biol. 208, 166 188.
56. Van Haaster LH, de Jong FH, Docter R, de Rooij DG (1993) High neonatal triiodothyronine levels reduce the period of Sertoli cell proliferation and accelerate tubular lumen formation in the rat testis, and increase serum inhibin levels. Endocrinology 133, 755 760.
57. Warn-Cramer BJ, Cottrell GT, Burt JM, Lau AF (1998) Regulation of connexin-43 gap junctional intercellular communication by mitogen-activated protein kinase. J. Biol. Chem. 273, 9188 9196.
58. Weber MJ, Evans PK, Johnson MA, McNair TF, Nakamura KD, Salter DW (1984) Transport of potassium, amino acids, and glucose in cells transformed by Rous sarcoma virus. Fed. Proc. 43, 107 112.
59. Xie X, Chan RJ, Yoder MC (2002) Thrombopoietin acts synergistically with LIF to maintain an undifferentiated state of embryonic stem cells homozygous for a Shp-2 deletion mutation. FEBS Lett. 529, 361 364.
60. Yamanouchi K, Yada E, Ishiguro N, Nishihara M (2007) 18α- Glycyrrhetinic acid Induces phenotypic changes of skeletal muscle cells to enter adipogenesis. Cell. Physiol. Biochem. 20, 781 790.
61. Zhang Y, Kakinuma Y, Ando M, Katare RG, Yamasaki F, Suqiura T, Sato T (2006) Acetylcholine inhibits the hypoxia-induced reduction of connexin 43 protein in rat cardiomyocytes. J. Pharmacol. Sci. 101, 214 222.