Numb-associated kinase interacts with the phosphotyrosine binding domain of Numb and antagonizes the function of Numb in vivo

Molecular and Cellular Biology

Volumn 18, Issue 1, 1998, Pages 598-607

  Chien, Cheng Ting ^a,b   Wang, Shuwen ^a   Rothenberg, Michael ^a   Jan, Lily Y ^a   Jan, Yuh Nung ^a  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b INSTITUTE OF MOLECULAR BIOLOGY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; INSULIN RECEPTOR SUBSTRATE 1; PROTEIN SERINE THREONINE KINASE;

ANIMAL CELL; ARTICLE; CELL DIVISION; CELL TRANSFORMATION; CELLULAR DISTRIBUTION; DROSOPHILA; ENZYME BINDING; GENE DOSAGE; GENE OVEREXPRESSION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION;

ANIMALIA;

EID: 0031962189     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.18.1.598     Document Type: Article

References (57)

1. Ashburner, M. 1989. Drosophila: a laboratory handbook. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
2. Bailey, A. M., and J. W. Posakony. 1995. Suppressor of Hairless directly activates transcription of Enhancer of split complex genes in response to Notch receptor activity. Genes Dev. 9:2609-2622.
3. Bartel, P. L., C.-T. Chien, R. Sternglanz, and S. Fields. 1993. Elimination of false positives that arise in using the two-hybrid system. BioTechniques 14:920-924.
4. Bartel, P. L., C.-T. Chien, R. Sternglanz, and S. Fields. 1993. Using the two-hybrid system to detect protein-protein interactions, p. 153-179. In D. A. Hartley (ed.), Cellular interaction in development: a practical approach. Oxford University Press, Oxford, England.
5. Blaikie, P., D. Immanuel, J. Wu, N. Li, V. Yajnik, and B. Margolis. 1994. A region in Shc distinct from the SH2 domain can bind tyrosine-phosphorylated growth factor receptors. J. Biol. Chem. 269:32031-32034.
6. Borg, J. P., J. Ooi, E. Levy, and B. Margolis. 1996. The phosphotyrosine interaction domains of X11 and FE65 bind to distinct sites on the YENPTY motif of amyloid precursor protein. Mol. Cell. Biol. 16:6229-6241.
7. Bork, P., and B. Margolis. 1995. A phosphotyrosine interaction domain. Cell 80:693-694.
8. Brand, A. H., and N. Perrimon. 1993. Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118:401-415.
9. Brewster, R., and R. Bodmer. 1995. Origin and specification of type 11 sensory neurons in Drosophila. Development 121:2923-2936.
10. Campos-Ortega, J. A. 1996. Numb diverts Notch pathway off the Tramtrack. Neuron 17:1-4.
11. Charest, A., J. Wagner, S. Jacob, C. J. McGlade, and M. L. Tremblay. 1996. Phosphotyrosine-independent binding of SHC to the NPLH sequence of murine protein-tyrosine phosphatase-PEST. Evidence for extended phosphotyrosine binding/phosphotyrosine interaction domain recognition specificity. J. Biol. Chem. 271:8424-8429.
12. Chien, C.-T., M. Rothernberg, L. Y. Jan, and Y. N. Jan. Unpublished data.
13. Chien, C.-T., P. Bartel, R. Sternglanz, and S. Fields. 1991. The two-hybrid system: a method to identify and clone genes for proteins that interact with a protein of interest. Proc. Natl. Acad. Sci. USA 88:9578-9582.
14. Cleghon, V., U. Gayko, T. D. Copeland, L. A. Perkins, N. Perrimon, and D. K. Morrison. 1996. Drosophila terminal structure development is regulated by the compensatory activities of positive and negative phosphotyrosine signaling sites on the Torso RTK. Genes Dev. 10:566-577.
15. Durfee, T., K. Becherer, P. L. Chen, S. H. Yeh, Y. Yang, A. E. Kilburn, W. H. Lee, and S. J. Elledge. 1993. The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit. Genes Dev. 7:555-569.
16. Eck, M. J., S. Dhe-Paganon, T. Trub, R. T. Nolte, and S. E. Shoelson. 1996. Structure of the IRS-1 PTB domain bound to the juxtamembrane region of the insulin receptor. Cell 85:695-705.
17. Ferguson, K. M., M. A. Lemmon, J. Schlessinger, and P. B. Sigler. 1995. Structure of the high affinity complex of inositol triphosphate with a phospholipase C pleckstrin homology domain. Cell 83:1037-1046.
18. Frise, E., J. A. Knoblich, S. Younger-Shepherd, L. Y. Jan, and Y. N. Jan. 1996. The Drosophila Numb protein inhibits signaling of the Notch receptor during cell-cell interaction in sensory organ lineage. Proc. Natl. Acad. Sci. USA 93:11925-11932.
19. Guo, M., E. Bier, L. Y. Jan, and Y. N. Jan. 1995. tramtrack acts downstream of numb to specify distinct daughter cell fates during asymmetric cell divisions in the Drosophila PNS. Neuron 14:913-925.
20. Guo, M., L. Y. Jan, and Y. N. Jan. 1996. Control of daughter cell fate during asymmetric division: interaction of Numb and Notch. Neuron 17:27-41.
21. Guo, S., and K. J. Kemphues. 1995. par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative ser/thr kinase that is asymmetrically distributed. Cell 81:611-620.
22. Guo, S., and K. J. Kemphues. 1996. A non-muscle myosin required for embryonic polarity in Caenorhabditis elegans. Nature 382:455-158.
23. Gustafson, T. A., W. He, A. Craparo, C. D. Schaub, and T. J. O'Neill. 1995. Phosphotyrosine-dependent interaction of Shc and IRS-1 with the NPXY motif of the insulin receptor via a novel non-SH2 domain. Mol. Cell. Biol. 15:2500-2508.
24. Hannon, G. J., D. Demetrick, and D. Beach. 1993. Isolation of the Rb-related p130 through its interaction with CDK2 and cyclins. Genes Dev. 7:2378-2391.
25. Harrison, S. C. 1996. Peptide-surface association: the case of PDZ and PTB domains. Cell 86:341-343.
26. Hartenstein, V., and J. W. Posakony. 1989. Development of adult sensilla on the wing and notum of Drosophila melanogaster. Development 107:389-405.
27. Hartenstein, V., and J. W. Posakony. 1990. A dual function of the Notch gene in Drosophila sensillum development. Dev. Biol. 142:13-30.
28. He, W., A. Craparo, Y. Zhu, T. J. O'Neill, L. M. Wang, J. H. Pierce, and T. A. Gustafson. 1996. Interaction of insulin receptor substrate-2 with the insulin and IGF-1 receptors: evidence for two-distinct phosphotyrosine-dependent interaction domains within IRS-2. J. Biol. Chem. 271:11641-11645.
29. He, W., T. J. O'Neill, and T. A. Gustafson. 1995. Distinct modes of interaction of SHC and insulin receptor substrate-1 with insulin receptor NPXY region via non-SH2 domains. J. Biol. Chem. 270:23258-23262.
30. Hinz, U., B. Giebel, and J. A. Campos-Ortega. 1994. The basic-helix-loop-helix domain of Drosophila lethal of scute protein is sufficient for proneural function and activates neurogenic genes. Cell 76:77-88.
31. Hollenberg, S. M., R. Sternglanz, P. F. Cheng, and H. Weintraub. 1995. Identification of a new family of tissue-specific basic helix-loop-helix proteins with a two-hybrid system. Mol. Cell. Biol. 15:3813-3822.
32. Horvitz, H. R., and I. Herskowitz. 1992. Mechanisms of asymmetric cell division: two Bs or not two Bs, that is the question. Cell 68:237-255.
33. Jan, Y. N., and L. Y. Jan. 1995. Maggot's hair and bug's eye: role of cell interactions and intrinsic factors in cell fate specification. Neuron 14:1-5.
34. Kavanaugh, W. M., C. W. Turck, and L. T. William. 1995. PTB domain binding to signaling proteins through a sequence motif containing phosphotyrosine. Science 268:1177-1179.
35. Kavanaugh, W. M., and L. T. William. 1994. An alternative to SH2 domains for binding tyrosine-phosphorylated proteins. Science 266:1862-1865.
36. Knoblich, J. A., L. Y. Jan, and Y. N. Jan. 1995. Asymmetric segregation of Numb and Prospero during cell division. Nature 377:624-627.
37. Lecourtois, M., and F. Schweisguth. 1995. The neurogenic Suppressor of Hairless DNA-binding protein mediates the transcriptional activation of the Enhancer of split complex genes triggered by Notch signaling. Genes Dev. 9:2598-2608.
38. Lemmon, M. A., K. M. Ferguson, and J. Schlessinger. 1996. PH domains diverse sequences with a common fold recruit signaling molecules to the cell surface. Cell 85:621-624.
39. Li, S.-C., S. Zhou, S. J. F. Vincent, C. Zwahlen, S. Wiley, L. Cantley, L. E. Kay, J. Forman-Kay, and T. Pawson. 1997. High-affinity binding of the Drosophila Numb phosphotyrosine-binding domain to peptides containing a Gly-Pro-(p)Tyr motif. Proc. Natl. Acad. Sci. USA 94:7204-7209.
40. Ohkura, H., I. M. Hagan, and D. M. Glover. 1995. The conserved Schizosaccharomyces pombe kinase plo1, required to form a biopolar spindle, the actin ring, and septum, can drive septum formation in G1 and G2 cells Genes Dev. 9:1059-1073.
41. Parks, A., and M. A. Muskavitch. 1993. Delta function is required for bristle organ determination and morphogenesis in Drosophila. Dev. Biol. 157:484-496.
42. Posakony, J. W. 1994. Nature versus nurture: asymmetric cell divisions in Drosophila bristle development. Cell 76:415-418.
43. Rhyu, M., L. Jan, and Y. N. Jan. 1994. Asymmetric distribution of numb protein during division of the sensory organ precursor confers distinct fates to daughter cells. Cell 76:477-491.
44. Rubin, G. M., and A. C. Spradling. 1982. Genetic transformation of Drosophila with transposable element vectors. Science 218:348-353.
45. Schonbaum, C. P., E. L. Organ, S. Qu, and D. R. Cavener. 1992. The Drosophila melanogaster stranded at second (sas) gene encodes a putative epidermal cell surface receptor required for larval development. Dev. Biol. 151-431-445.
46. Schweisguth, F., and J. W. Posakony. 1994. Antagonistic activities of Suppressor-of-Hairless and Hairless control alternative cell fates in the Drosophila adult epidermis. Development 120:1433-1441.
47. Spana, E. P., and C. Q. Doe. 1996. Numb antagonizes Notch signaling to specify sibling neuron cell fates. Neuron 17:21-26.
48. Spana, E. P., C. Kopczynski, C. S. Goodman, and C. Q. Doe. 1995. Asymmetric localization of numb autonomously determines sibling neuron identity in the Drosophila CNS. Development 121:3489-3494.
49. Tata, F., and D. A. Hartley. 1995. Inhibition of cell fate in Drosophila by Enhancer of split genes. Mech. Dev. 51:305-315.
50. Uemura, T., S. Shepherd, L. Ackerman, L. Y. Jan, and Y. N. Jan. 1989. numb, a gene required in determination of cell fate during sensory organ formation in Drosophila embryos. Cell 58:349-360.
51. Vaessin, H., E. Grell, E. Wolff, E. Bier, L. Y. Jan, and Y. N. Jan. 1991. prospero is expressed in neuronal precursors and encodes a nuclear protein that is involved in the control of axonal outgrowth in Drosophila. Cell 67: 941-953.
52. Verdi, J. M., R. Schmandt, A. Bashirullah, S. Jacob, R. Salvino, C. G. Craig, A. E. Program, H. D. Lipshitz, and C. J. McGlade. 1996. Mammalian NUMB is an evolutionary conserved signaling adapter protein that specifies cell fate. Curr. Biol. 6:1134-1145.
53. Wolf, G., T. Trub, E. Ottinger, L. Groninga, A. Lynch, M. F. White, M. Miyazaki, J. Lee, and S. E. Shoelson. 1995. PTB domains of IRS-1 and Shc have distinct hut overlapping binding specificities. J. Biol. Chem. 270:27407-27410.
54. Zhong, W., J. N. Feder, M.-M. Jiang, L. Y. Jan, and Y. N. Jan. 1996. Asymmetric localization of a mammalian Numb homolog during mouse cortical neurogenesis. Neuron 17:43-53.
55. Zhong, W., M-M. Jiang, G. Weinmaster, L. Y. Jan, and Y. N. Jan. 1997. Differential expression of mammalian Numb homologues and Notch1 suggests distinct roles during mouse cortical neurogenesis. Development 124: 1887-1897.
56. Zhou, M.-M., K. S. Ravichandran, E. T. Olejniczak, A. M. Petros, R. P. Meadows, M. Sattler, J. E. Harlan, W. S. Wade, S. J. Burakoff, and S. W. Fesik. 1995. Structure and ligand recognition of the phosphotyrosine binding domain of Shc. Nature 378:584-592.
57. Zipursky, S. L., T. R. Venkatesh, D. B. Teplow, and S. Benzer. 1984. Neuronal development in the Drosophila retina: Monoclonal antibodies as molecular probes. Cell 36:15-26.