Comparison of FcERI-and FcγRI-mediated degranulation and TNF-α synthesis in human mast cells: Selective utilization of phosphatidylinositol-3-kinase for FcγCRI-induced degranulation

European Journal of Immunology

Volumn 33, Issue 5, 2003, Pages 1450-1459

  Okayama, Yoshimichi ^a   Tkaczyk, Christine ^a   Metcalfe, Dean D ^a   Gilfillan, Alasdair M ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

Fc receptor; Human mast cell; MAP kinase; P72syk; Phosphatidylinositol 3 kinase; Signal transduction; Src kinase

Indexed keywords

CD34 ANTIGEN; FC RECEPTOR; GAMMA INTERFERON; IMMUNOGLOBULIN E RECEPTOR; IMMUNOGLOBULIN G; MITOGEN ACTIVATED PROTEIN KINASE 1; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE P60; SYNAPTOPHYSIN; TUMOR NECROSIS FACTOR ALPHA; TYROSINE; ENZYME PRECURSOR; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE SYK; PROTEIN TYROSINE KINASE; SIGNAL PEPTIDE;

ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; MAST CELL DEGRANULATION; MEDIATOR RELEASE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; ANIMAL; BIOSYNTHESIS; COMPARATIVE STUDY; DEGRANULATION; MAST CELL; METABOLISM; MOUSE; PHOSPHORYLATION; PHYSIOLOGY;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; CELL DEGRANULATION; ENZYME PRECURSORS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MAST CELLS; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTEIN-TYROSINE KINASES; RECEPTORS, IGE; RECEPTORS, IGG; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; TUMOR NECROSIS FACTOR-ALPHA; TYROSINE;

EID: 0038297113     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.200323563     Document Type: Article

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