메뉴 건너뛰기




Volumn 97, Issue 11, 2009, Pages 2867-2875

Reversible phosphorylation subserves robust circadian rhythms by creating a switch in inactivating the positive element

Author keywords

[No Author keywords available]

Indexed keywords

FRQ PROTEIN; PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR WHITE COLLAR COMPLEX; UNCLASSIFIED DRUG;

EID: 72249103873     PISSN: 00063495     EISSN: 15420086     Source Type: Journal    
DOI: 10.1016/j.bpj.2009.09.008     Document Type: Article
Times cited : (9)

References (53)
  • 1
    • 0033593306 scopus 로고    scopus 로고
    • Molecular bases for circadian clocks
    • Dunlap, J. C. 1999. Molecular bases for circadian clocks. Cell. 96: 271-290.
    • (1999) Cell , vol.96 , pp. 271-290
    • Dunlap, J.C.1
  • 2
    • 0037194790 scopus 로고    scopus 로고
    • Coordination of circadian timing in mammals
    • Reppert, S. M., and D. R. Weaver. 2002. Coordination of circadian timing in mammals. Nature. 418:935-941.
    • (2002) Nature , vol.418 , pp. 935-941
    • Reppert, S.M.1    Weaver, D.R.2
  • 3
    • 0035458732 scopus 로고    scopus 로고
    • Time zones: A comparative genetics of circadian clocks
    • Young, M. W., and S. A. Kay. 2001. Time zones: a comparative genetics of circadian clocks. Nat. Rev. Genet. 2:702-715.
    • (2001) Nat. Rev. Genet. , vol.2 , pp. 702-715
    • Young, M.W.1    Kay, S.A.2
  • 4
    • 33749402900 scopus 로고    scopus 로고
    • Proteins in the Neurospora circadian clockworks
    • Dunlap, J. C. 2006. Proteins in the Neurospora circadian clockworks. J. Biol. Chem. 281:28489-28493.
    • (2006) J. Biol. Chem. , vol.281 , pp. 28489-28493
    • Dunlap, J.C.1
  • 5
    • 34247161251 scopus 로고    scopus 로고
    • The Neurospora crassa circadian clock
    • Heintzen, C., and Y. Liu. 2007. The Neurospora crassa circadian clock. Adv. Genet. 58:25-66.
    • (2007) Adv. Genet. , vol.58 , pp. 25-66
    • Heintzen, C.1    Liu, Y.2
  • 6
    • 41049088736 scopus 로고    scopus 로고
    • Interlocked feedback loops of the circadian clock of Neurospora crassa
    • Brunner, M., and K. Káldi. 2008. Interlocked feedback loops of the circadian clock of Neurospora crassa. Mol. Microbiol. 68:255-262.
    • (2008) Mol. Microbiol. , vol.68 , pp. 255-262
    • Brunner, M.1    Káldi, K.2
  • 7
    • 0030982250 scopus 로고    scopus 로고
    • Neurospora wc- 1 and wc-2: Transcription, photoresponses, and the origins of circadian rhythmicity
    • Crosthwaite, S. K., J. C. Dunlap, and J. J. Loros. 1997. Neurospora wc- 1 and wc-2: transcription, photoresponses, and the origins of circadian rhythmicity. Science. 276:763-769.
    • (1997) Science , vol.276 , pp. 763-769
    • Crosthwaite, S.K.1    Dunlap, J.C.2    Loros, J.J.3
  • 8
    • 0036135673 scopus 로고    scopus 로고
    • PAS domain-mediated WC-1/WC-2 interaction is essential for maintaining the steady-state level of WC-1 and the function of both proteins in circadian clock and light responses of Neurospora
    • Cheng, P., Y. Yang, K. H. Gardner, and Y. Liu. 2002. PAS domain-mediated WC-1/WC-2 interaction is essential for maintaining the steady-state level of WC-1 and the function of both proteins in circadian clock and light responses of Neurospora. Mol. Cell. Biol. 22: 517-524.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 517-524
    • Cheng, P.1    Yang, Y.2    Gardner, K.H.3    Liu, Y.4
  • 9
    • 0028258994 scopus 로고
    • Negative feedback defining a circadian clock: Autoregulation of the clock gene frequency
    • Aronson, B. D., K. A. Johnson, J. J. Loros, and J. C. Dunlap. 1994. Negative feedback defining a circadian clock: autoregulation of the clock gene frequency. Science. 263:1578-1584.
    • (1994) Science , vol.263 , pp. 1578-1584
    • Aronson, B.D.1    Johnson, K.A.2    Loros, J.J.3    Dunlap, J.C.4
  • 10
    • 0035863123 scopus 로고    scopus 로고
    • Coiled-coil domain-mediated FRQ-FRQ interaction is essential for its circadian clock function in Neurospora
    • DOI 10.1093/emboj/20.1.101
    • Cheng, P., Y. Yang, C. Heintzen, and Y. Liu. 2001. Coiled-coil domain-mediated FRQ-FRQ interaction is essential for its circadian clock function in Neurospora. EMBO J. 20:101-108. (Pubitemid 32099106)
    • (2001) EMBO Journal , vol.20 , Issue.1-2 , pp. 101-108
    • Cheng, P.1    Yang, Y.2    Heintzen, C.3    Liu, Y.4
  • 11
    • 0035863191 scopus 로고    scopus 로고
    • WC-2 mediates WC- 1-FRQ interaction within the PAS protein-linked circadian feedback loop of Neurospora
    • Denault, D. L., J. J. Loros, and J. C. Dunlap. 2001. WC-2 mediates WC- 1-FRQ interaction within the PAS protein-linked circadian feedback loop of Neurospora. EMBO J. 20:109-117.
    • (2001) EMBO J. , vol.20 , pp. 109-117
    • Denault, D.L.1    Loros, J.J.2    Dunlap, J.C.3
  • 12
    • 0037947690 scopus 로고    scopus 로고
    • Rhythmic binding of a WHITE COLLAR-containing complex to the frequency promoter is inhibited by FREQUENCY
    • Froehlich, A. C., J. J. Loros, and J. C. Dunlap. 2003. Rhythmic binding of a WHITE COLLAR-containing complex to the frequency promoter is inhibited by FREQUENCY. Proc. Natl. Acad. Sci. USA. 100:5914-5919.
    • (2003) Proc. Natl. Acad. Sci. USA. , vol.100 , pp. 5914-5919
    • Froehlich, A.C.1    Loros, J.J.2    Dunlap, J.C.3
  • 13
    • 33745145846 scopus 로고    scopus 로고
    • Transcriptional and post-transcriptional regulation of the circadian clock of cyanobacteria and Neurospora
    • Brunner, M., and T. Schafmeier. 2006. Transcriptional and post-transcriptional regulation of the circadian clock of cyanobacteria and Neurospora. Genes Dev. 20:1061-1074.
    • (2006) Genes Dev. , vol.20 , pp. 1061-1074
    • Brunner, M.1    Schafmeier, T.2
  • 14
    • 0035449932 scopus 로고    scopus 로고
    • Modeling circadian oscillations with interlocking positive and negative feedback loops
    • Smolen, P., D. A. Baxter, and J. H. Byrne. 2001. Modeling circadian oscillations with interlocking positive and negative feedback loops. J. Neurosci. 21:6644-6656. (Pubitemid 32781109)
    • (2001) Journal of Neuroscience , vol.21 , Issue.17 , pp. 6644-6656
    • Smolen, P.1    Baxter, D.A.2    Byrne, J.H.3
  • 15
    • 22144490453 scopus 로고    scopus 로고
    • A model for the Neurospora circadian clock
    • Francois, P. 2005. A model for the Neurospora circadian clock. Biophys. J. 88:2369-2383.
    • (2005) Biophys. J. , vol.88 , pp. 2369-2383
    • Francois, P.1
  • 16
    • 22744455874 scopus 로고    scopus 로고
    • Transcriptional feedback of Neurospora circadian clock gene by phosphorylation-dependent inactivation of its transcription factor
    • DOI 10.1016/j.cell.2005.05.032, PII S0092867405005933
    • Schafmeier, T., A. Haase, K. Káldi, J. Scholz, M. Fuchs, et al. 2005. Transcriptional feedback of Neurospora circadian clock gene by phosphorylation- dependent inactivation of its transcription factor. Cell. 122:235-246. (Pubitemid 41032987)
    • (2005) Cell , vol.122 , Issue.2 , pp. 235-246
    • Schafmeier, T.1    Haase, A.2    Kaldi, K.3    Scholz, J.4    Fuchs, M.5    Brunner, M.6
  • 17
    • 33748687611 scopus 로고    scopus 로고
    • CKI and CKII mediate the FREQUENCY-dependent phosphorylation of the WHITE COLLAR complex to close the Neurospora circadian negative feedback loop
    • DOI 10.1101/gad.1463506
    • He, Q., J. Cha, Q. He, H.-C. Lee, Y. Yang, et al. 2006. CKI and CKII mediate the FREQUENCY-dependent phosphorylation of the WHITE COLLAR complex to close the Neurospora circadian negative feedback loop. Genes Dev. 20:2552-2565. (Pubitemid 44396840)
    • (2006) Genes and Development , vol.20 , Issue.18 , pp. 2552-2565
    • He, Q.1    Cha, J.2    He, Q.3    Lee, H.-C.4    Yang, Y.5    Liu, Y.6
  • 18
    • 33847779219 scopus 로고    scopus 로고
    • Post-translational modifications regulate the ticking of the circadian clock
    • Gallego, M., and D. M. Virshup. 2007. Post-translational modifications regulate the ticking of the circadian clock. Nat. Rev. Mol. Cell Biol. 8:139-148.
    • (2007) Nat. Rev. Mol. Cell Biol. , vol.8 , pp. 139-148
    • Gallego, M.1    Virshup, D.M.2
  • 19
    • 17244373578 scopus 로고    scopus 로고
    • Reconstitution of circadian oscillation of cyanobacterial KaiC phosphorylation in vitro
    • DOI 10.1126/science.1108451
    • Nakajima, M., K. Imai, H. Ito, T. Nishiwaki, Y. Murayama, et al. 2005. Reconstitution of circadian oscillation of cyanobacterial KaiC phosphorylation in vitro. Science. 308:414-415. (Pubitemid 40530079)
    • (2005) Science , vol.308 , Issue.5720 , pp. 414-415
    • Nakajima, M.1    Imai, K.2    Ito, H.3    Nishiwaki, T.4    Murayama, Y.5    Iwasaki, H.6    Oyama, T.7    Kondo, T.8
  • 20
    • 12244296161 scopus 로고    scopus 로고
    • No transcription-translation feedback in circadian rhythm of KaiC phosphorylation
    • DOI 10.1126/science.1102540
    • Tomita, J., M. Nakajima, T. Kondo, and H. Iwasaki. 2005. No translation feedback in circadian rhythm of KaiC phosphorylation. Science. 307:251-254. (Pubitemid 40116239)
    • (2005) Science , vol.307 , Issue.5707 , pp. 251-254
    • Tomita, J.1    Nakajima, M.2    Kondo, T.3    Iwasaki, H.4
  • 21
    • 0034617102 scopus 로고    scopus 로고
    • Interconnected feedback loops in the Neurospora circadian system
    • DOI 10.1126/science.289.5476.107
    • Lee, K., J. J. Loros, and J. C. Dunlap. 2000. Interconnected feedback loops in the Neurospora circadian system. Science. 289:107-110. (Pubitemid 30463301)
    • (2000) Science , vol.289 , Issue.5476 , pp. 107-110
    • Lee, K.1    Loros, J.J.2    Dunlap, J.C.3
  • 22
    • 0035912804 scopus 로고    scopus 로고
    • Interlocked feedback loops contribute to the robustness of the Neurospora circadian clock
    • Cheng, P., Y. H. Yang, and Y. Liu. 2001. Interlocked feedback loops contribute to the robustness of the Neurospora circadian clock. Proc. Natl. Acad. Sci. USA. 98:7408-7413.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 7408-7413
    • Cheng, P.1    Yang, Y.H.2    Liu, Y.3
  • 23
    • 0141843566 scopus 로고    scopus 로고
    • Saturation of enzyme kinetics in circadian clock models
    • Kurosawa, G., and Y. Iwasa. 2002. Saturation of enzyme kinetics in circadian clock models. J. Biol. Rhythms. 17:568-577.
    • (2002) J. Biol. Rhythms. , vol.17 , pp. 568-577
    • Kurosawa, G.1    Iwasa, Y.2
  • 24
    • 0033382101 scopus 로고    scopus 로고
    • The Goodwin oscillator: On the importance of degradation reactions in the circadian clock
    • Ruoff, P., M. Vinsjevik, C. Monnerjahn, and L. Rensing. 1999. The Goodwin oscillator: on the importance of degradation reactions in the circadian clock. J. Biol. Rhythms. 14:469-479.
    • (1999) J. Biol. Rhythms. , vol.14 , pp. 469-479
    • Ruoff, P.1    Vinsjevik, M.2    Monnerjahn, C.3    Rensing, L.4
  • 25
    • 0030964184 scopus 로고    scopus 로고
    • Thermally regulated translational control of FRQ mediates aspects of temperature responses in the Neurospora circadian clock
    • DOI 10.1016/S0092-8674(00)80228-7
    • Liu, Y., N. Y. Garceau, J. J. Loros, and J. C. Dunlap. 1997. Thermally regulated translational control of FRQ mediates aspects of temperature responses in the Neurospora circadian clock. Cell. 89:477-486. (Pubitemid 27220892)
    • (1997) Cell , vol.89 , Issue.3 , pp. 477-486
    • Liu, Y.1    Garceau, N.Y.2    Loros, J.J.3    Dunlap, J.C.4
  • 26
    • 33645429016 scopus 로고
    • Exact stochastic simulation of coupled chemical reactions
    • Gillespie, D. 1977. Exact stochastic simulation of coupled chemical reactions. J. Chem. Phys. 81:2340-2361.
    • (1977) J. Chem. Phys. , vol.81 , pp. 2340-2361
    • Gillespie, D.1
  • 27
    • 0031006674 scopus 로고    scopus 로고
    • Alternative initiation of translation and time-specific phosphorylation yield multiple forms of the essential clock protein FREQUENCY
    • Garceau, N. Y., Y. Liu, J. J. Loros, and J. C. Dunlap. 1997. Alternative initiation of translation and time-specific phosphorylation yield multiple forms of the essential clock protein FREQUENCY. Cell. 89:469-476.
    • (1997) Cell , vol.89 , pp. 469-476
    • Garceau, N.Y.1    Liu, Y.2    Loros, J.J.3    Dunlap, J.C.4
  • 28
    • 0030990993 scopus 로고    scopus 로고
    • Dissection of a circadian oscillation into discrete domains
    • Merrow, M. W., N. Y. Garceau, and J. C. Dunlap. 1997. Dissection of a circadian oscillation into discrete domains. Proc. Natl. Acad. Sci. USA. 94:3877-3882.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 3877-3882
    • Merrow, M.W.1    Garceau, N.Y.2    Dunlap, J.C.3
  • 29
    • 33746605149 scopus 로고    scopus 로고
    • Minimal model of spiky oscillations in NF-κB signaling
    • Krishna, S., M. H. Jensen, and K. Sneppen. 2006. Minimal model of spiky oscillations in NF-κB signaling. Proc. Natl. Acad. Sci. USA. 103:10840-10845.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 10840-10845
    • Krishna, S.1    Jensen, M.H.2    Sneppen, K.3
  • 30
    • 0029047917 scopus 로고
    • Light-induced resetting of a circadian clock is mediated by a rapid increase in frequency transcript
    • Crosthwaite, S. K., J. J. Loros, and J. C. Dunlap. 1995. Light-induced resetting of a circadian clock is mediated by a rapid increase in frequency transcript. Cell. 81:1003-1012.
    • (1995) Cell , vol.81 , pp. 1003-1012
    • Crosthwaite, S.K.1    Loros, J.J.2    Dunlap, J.C.3
  • 31
    • 0033375755 scopus 로고    scopus 로고
    • Limit cycle models for circadian rhythms based on transcriptional regulation in Drosophila and Neurospora
    • Leloup, J., D. Gonze, and A. Goldbeter. 1999. Limit cycle models for circadian rhythms based on transcriptional regulation in Drosophila and Neurospora. J. Biol. Rhythms. 14:433-448.
    • (1999) J. Biol. Rhythms. , vol.14 , pp. 433-448
    • Leloup, J.1    Gonze, D.2    Goldbeter, A.3
  • 32
    • 0027994487 scopus 로고
    • Circadian clock locus frequency: Protein encoded by a single open reading frame defines period length and temperature compensation
    • Aronson, B. D., K. A. Johnson, and J. C. Dunlap. 1994. Circadian clock locus frequency: protein encoded by a single open reading frame defines period length and temperature compensation. Proc. Natl. Acad. Sci. USA. 91:7683-7687.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 7683-7687
    • Aronson, B.D.1    Johnson, K.A.2    Dunlap, J.C.3
  • 33
    • 8644277897 scopus 로고    scopus 로고
    • Circadian rhythms in micro-organisms: New complexities
    • Lakin-Thomas, P. L., and S. Brody. 2004. Circadian rhythms in micro-organisms: new complexities. Annu. Rev. Microbiol. 58:489-519.
    • (2004) Annu. Rev. Microbiol. , vol.58 , pp. 489-519
    • Lakin-Thomas, P.L.1    Brody, S.2
  • 34
    • 0032896632 scopus 로고    scopus 로고
    • The B regulatory subunit of protein phosphatase 2A is required for completion of macroconidiation and other developmental processes in Neurospora crassa
    • Yatzkan, E., and O. Yarden. 1999. The B regulatory subunit of protein phosphatase 2A is required for completion of macroconidiation and other developmental processes in Neurospora crassa. Mol. Microbiol. 31:197-209.
    • (1999) Mol. Microbiol. , vol.31 , pp. 197-209
    • Yatzkan, E.1    Yarden, O.2
  • 35
    • 1042266554 scopus 로고    scopus 로고
    • Distinct roles for PP1 and PP2A in the Neurospora circadian clock
    • DOI 10.1101/gad.1152604
    • Yang, Y., Q. He, P. Cheng, P. Wrage, O. Yarden, et al. 2004. Distinct roles for PP1 and PP2A in the Neurospora circadian clock. Genes Dev. 18:255-260. (Pubitemid 38199251)
    • (2004) Genes and Development , vol.18 , Issue.3 , pp. 255-260
    • Yang, Y.1    He, Q.2    Cheng, P.3    Wrage, P.4    Yarden, O.5    Liu, Y.6
  • 36
    • 4444322221 scopus 로고    scopus 로고
    • Robustness properties of circadian clock architectures
    • Stelling, J., E. D. Gilles, and F. J. Doyle. 2004. Robustness properties of circadian clock architectures. Proc. Natl. Acad. Sci. USA. 101:13210-13215.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 13210-13215
    • Stelling, J.1    Gilles, E.D.2    Doyle, F.J.3
  • 37
    • 0013823048 scopus 로고
    • Oscillatory behavior in enzymatic control processes
    • Goodwin, B. C. 1965. Oscillatory behavior in enzymatic control processes. Adv. Enzyme Regul. 3:425-438.
    • (1965) Adv. Enzyme Regul. , vol.3 , pp. 425-438
    • Goodwin, B.C.1
  • 38
    • 0032758081 scopus 로고    scopus 로고
    • A simple model of circadian rhythms based on dimerization and proteolysis of PER and TIM
    • Tyson, J. J., C. I. Hong, C. D. Thron, and B. Novak. 1999. A simple model of circadian rhythms based on dimerization and proteolysis of PER and TIM. Biophys. J. 77:2411-2417.
    • (1999) Biophys. J. , vol.77 , pp. 2411-2417
    • Tyson, J.J.1    Hong, C.I.2    Thron, C.D.3    Novak, B.4
  • 39
    • 0001424903 scopus 로고
    • An amplified sensitivity arising from covalent modification in biological systems
    • Goldbeter, A., and D. E. Koshland. 1981. An amplified sensitivity arising from covalent modification in biological systems. Proc. Natl. Acad. Sci. USA. 78:6840-6844.
    • (1981) Proc. Natl. Acad. Sci. USA , vol.78 , pp. 6840-6844
    • Goldbeter, A.1    Koshland, D.E.2
  • 40
    • 0020592357 scopus 로고
    • Phosphorylation of isocitrate dehydrogenase as a demonstration of enhanced sensitivity in covalent regulation
    • LaPorte, D. C., and D. E. Koshland. 1983. Phosphorylation of isocitrate dehydrogenase as a demonstration of enhanced sensitivity in covalent regulation. Nature. 305:286-290.
    • (1983) Nature , vol.305 , pp. 286-290
    • LaPorte, D.C.1    Koshland, D.E.2
  • 41
    • 0022517716 scopus 로고
    • Zero-order ultra-sensitivity in the regulation of glycogen phosphorylase
    • Meinke, M. H., J. S. Bishop, and R. D. Edstrom. 1986. Zero-order ultra-sensitivity in the regulation of glycogen phosphorylase. Proc. Natl. Acad. Sci. USA. 83:2865-2868.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 2865-2868
    • Meinke, M.H.1    Bishop, J.S.2    Edstrom, R.D.3
  • 43
    • 0037376655 scopus 로고    scopus 로고
    • Sniffers, buzzers, toggles and blinkers: Dynamics of regulatory and signaling pathways in the cell
    • Tyson, J. J., K. C. Chen, and B. Novak. 2003. Sniffers, buzzers, toggles and blinkers: dynamics of regulatory and signaling pathways in the cell. Curr. Opin. Cell Biol. 15:221-231.
    • (2003) Curr. Opin. Cell Biol. , vol.15 , pp. 221-231
    • Tyson, J.J.1    Chen, K.C.2    Novak, B.3
  • 44
    • 0026006671 scopus 로고
    • A minimal cascade model for the mitotic oscillator involving cyclin and cdc2 kinase
    • Goldbeter, A. 1991. A minimal cascade model for the mitotic oscillator involving cyclin and cdc2 kinase. Proc. Natl. Acad. Sci. USA. 88: 9107-9111.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 9107-9111
    • Goldbeter, A.1
  • 45
    • 0034688220 scopus 로고    scopus 로고
    • Circadian clocks limited by noise
    • Barkai, N., and S. Leibler. 2000. Circadian clocks limited by noise. Nature. 403:267-268.
    • (2000) Nature , vol.403 , pp. 267-268
    • Barkai, N.1    Leibler, S.2
  • 46
    • 0037154231 scopus 로고    scopus 로고
    • Robustness of circadian rhythms with respect to molecular noise
    • Gonze, D., J. Halloy, and A. Goldbeter. 2002. Robustness of circadian rhythms with respect to molecular noise. Proc. Natl. Acad. Sci. USA. 99:673-678.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 673-678
    • Gonze, D.1    Halloy, J.2    Goldbeter, A.3
  • 48
    • 33747369652 scopus 로고    scopus 로고
    • Circadian rhythms in Neurospora crassa and other filamentous fungi
    • Liu, Y., and D. Bell-Pedersen. 2006. Circadian rhythms in Neurospora crassa and other filamentous fungi. Eukaryot. Cell. 5:1184-1193.
    • (2006) Eukaryot. Cell. , vol.5 , pp. 1184-1193
    • Liu, Y.1    Bell-Pedersen, D.2
  • 49
    • 67349174721 scopus 로고    scopus 로고
    • Activity of the circadian transcription factor White Collar Complex is modulated by phosphorylation of SP-motifs
    • Sancar, G., C. Sancar, M. Brunner, and T. Schafmeier. 2009. Activity of the circadian transcription factor White Collar Complex is modulated by phosphorylation of SP-motifs. FEBS Lett. 583:1833-1840.
    • (2009) FEBS Lett. , vol.583 , pp. 1833-1840
    • Sancar, G.1    Sancar, C.2    Brunner, M.3    Schafmeier, T.4
  • 51
    • 38949103460 scopus 로고    scopus 로고
    • Simulating dark expressions and interactions of frq and wc-1 in the Neurospora circadian clock
    • Hong, C. I., I. W. Jolma, J. J. Loros, J. C. Dunlap, and P. Ruoff. 2008. Simulating dark expressions and interactions of frq and wc-1 in the Neurospora circadian clock. Biophys. J. 94:1221-1232.
    • (2008) Biophys. J. , vol.94 , pp. 1221-1232
    • Hong, C.I.1    Jolma, I.W.2    Loros, J.J.3    Dunlap, J.C.4    Ruoff, P.5
  • 52
    • 0037126627 scopus 로고    scopus 로고
    • A PEST-like element in FREQUENCY determines the length of the circadian period in Neurospora crassa
    • DOI 10.1093/emboj/20.24.7074
    • Gorl, M., M. Merrow, B. Huttner, J. Johnson, T. Roenneberg, et al. 2001. A PEST-like element in FREQUENCY determines the length of the circadian period in Neurospora crassa. EMBO J. 20:7074-7084. (Pubitemid 34062299)
    • (2001) EMBO Journal , vol.20 , Issue.24 , pp. 7074-7084
    • Gorl, M.1    Merrow, M.2    Huttner, B.3    Johnson, J.4    Roenneberg, T.5    Brunner, M.6
  • 53
    • 0035966317 scopus 로고    scopus 로고
    • Posttranslational mechanisms regulate the mammalian circadian clock
    • DOI 10.1016/S0092-8674(01)00610-9
    • Lee, C., J. P. Etchegaray, F. R. Cagampang, A. S. Loudon, and S. M. Reppert. 2001. Posttranslational mechanisms regulate the mammalian circadian clock. Cell. 107:855-867. (Pubitemid 34084977)
    • (2001) Cell , vol.107 , Issue.7 , pp. 855-867
    • Lee, C.1    Etchegaray, J.-P.2    Cagampang, F.R.A.3    Loudon, A.S.I.4    Reppert, S.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.