Short report: Childhood coinfections with plasmodium falciparum and schistosoma mansoni result in lower percentages of activated T cells and T regulatory memory cells than schistosomiasis only

American Journal of Tropical Medicine and Hygiene

Volumn 80, Issue 3, 2009, Pages 475-478

  Mouk, Erick M O ^a   Mwinzi, Pauline N M ^a   Black, Carla L ^b   Carter, Jennifer M ^b   Ng'Ang'a, Zipporah W ^c   Gicheru, Michael M ^d   Evan Secor, W ^e   Karanja, Diana M S ^a   Colley, Daniel G ^b  

^a KENYA MEDICAL RESEARCH INSTITUTE   (Kenya)

^b UNIVERSITY OF GEORGIA   (United States)

^c JOMO KENYATTA UNIVERSITY OF AGRICULTURE AND TECHNOLOGY   (Kenya)

^d KENYATTA UNIVERSITY   (Kenya)

^e CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD45RO ANTIGEN; HLA DR ANTIGEN;

ARTICLE; CHILD; FEMALE; FLOW CYTOMETRY; HUMAN; MAJOR CLINICAL STUDY; MALARIA; MALE; PLASMODIUM FALCIPARUM; PRESCHOOL CHILD; REGULATORY T LYMPHOCYTE; SCHISTOSOMA MANSONI; SCHISTOSOMIASIS; SCHOOL CHILD; T LYMPHOCYTE ACTIVATION;

PLASMODIUM FALCIPARUM; SCHISTOSOMA MANSONI;

EID: 62949212581     PISSN: 00029637     EISSN: None     Source Type: Journal    
DOI: 10.4269/ajtmh.2009.80.475     Document Type: Article

References (33)

1. Brooker S, Akwale W. Pullan R. Estambale B, Clarke SE, Snow RW, Hotez JP, 2007. Epidemiology of Plasmodium-helminth co-infection in Africa: populations at risk, potential impact on anemia, and prospects for combining control. Am J Trop Med Hyg 77: 88-98.
2. Pierrot C, Wilson MS, Lallet H, Laffite S, Jones MF, Daher W, Capron M, Dunne DW, Khalife J, 2006. Identification of a novel antigen of Schistosoma mansoni shared with Plasmodium falciparum and evaluation of different cross-reactive antibody subclasses induced by human schistosomiasis and malaria. Infect Immun 74: 3347-3354.
3. Booth M, Vennervald BJ, Kenty L, Butterworth AE, Kariuki HC, Kadzo H. Ireri E, Amaganga C, Kimani G, Mwatha JK, Otedo A, Ouma JH, Muchiri E, Dunne DW, 2004. Micro-geographical variation in exposure to Schistosoma mansoni and malaria, and exacerbation of splenomegaly in Kenyan school-aged children. BMC Infect Dis 4:13.
4. Briand S, Watier L, Jay LEH, Garcia A, Cot M, 2005. Coinfection with Plasmodium falciparum and Schistosoma haematobium: protective effect of schistosomiasis on malaria in senegaleese children? Am J Trop Med Hyg 72:702-707.
5. Le Hesran JY, Akaina JN, Diaye EHM. Dia M, Sengor P, Konate L, 2004. Severe malaria attack associated with high prevalence of Ascaris lumbricoides infection among children in rural Senegal. Am J Trop Med Hyg 98:397-399.
6. Lyke KE, Dicko A, Dabo A, Sangare L, Kone A, Coulibaly D, Guido A, Traore K, Daou M, Diarra I, Sztein MB, Plowe CB.
7. Doumbo KO, 2005. Association of Schistosoma haematobium infection with protection against acute Plasmodium falciparum malaria in Malian children. Am J Trop Med Hyg 73:1124-1130.
8. Mwangi TW. Bethony JM, Brooker S, 2006. Malaria and helminthic interactions in humans: an epidemiological viewpoint. Ann Trop Med Parasitol 100:551-570.
9. Nacher M, Gay F, Sighhasivanon P, Krudsood S, Treeprasertsuk S, Mazier D, Vouldoukis I, Looareesuwan S, 2000. Ascaris lumri- coides infection is associated with protection from cerebral malaria. Parasite Immunol 22: 107-113.
10. Petney TN, Andrews RH, 1998. Multiparasite communities in animals and humans: frequency, structure and pathogenic significance. Int J Parasitol 28:377-393.
11. Druilhe P, Tall A, 2005. Worms can worsen malaria: towards a new means to roll back malaria. Trends Parasitol 21:359-362.
12. Stothaard JR, Gabrieli AF, 2007. Schistosomiasis in African infants and preschool children: to treat or not to treat. Trends Immunol 23: 83-88.
13. Engels D, Chitsulo L, Montresor A, Savioli L, 2002. The global epidemiological situation of schistosomiaisis and new approaches to control and research. Act Trop 82:139-146.
14. Gryseels B, Polman K, Clerinx J. Kestens L, 2006. Human schistosomiasis. Lancet 368: 1106-1118.
15. Millington OR, Gibson BV, Rush CM, Zinselmeyer R, Stephen P, Garside P, Brewer MJ, 2007. Malaria impairs T cell clustering and immune priming despite normal signal 1 from dendritic cells. PLoS Pathog 3:143.
16. Watanabe K, Mwinzi PMN, Black CL, Muok EOM, Karanja DMS, Secor WE, Colley DG 2007.T regulatory cells decrease in people infected with Schistosoma mansoni upon effective treatment. Am J Trop Med Hyg 77: 676-682.
17. Walther M,Tongren JE, Andrews L, Korbel D, King E, Fletcher H, Andersen RF. Bejon P, Thompson F, Dunachie SJ, Edele F, de Souza JB, Sinden RE, Gilbert SC, Riley EM, Hill AV, 2005. Upregulation of TGF beta, FOXP3 and CD4+CD25+ regulatory T cell correlates with more rapid parasite growth in human malaria infection. Immunity 23:287-296.
18. Handzel T, Karanja DMS, Addis DG, Allen WH, Rosen DH, Colley DG, Andove J, Slutsker L, Secor WE, 2003. Geographic distribution of schistosomiasis and soil transmitted helminths in Western Kenya: implication of antihelminthic mass treatment. Am J Trop Med Hyg 69: 318-323.
19. Bayry J, Triebei F, Kaveri SV, Tough DF, 2007. Human dendritic cells acquire a semimature phenotype and lymph node homing potential through interaction with CD4+CD25+ regulatory T cells. J Immunol 178: 4184-4193.
20. Duggleby RC, Shaw TN, Jarvis LB, Gaston JS, 2007. CD27 expression discriminates between regulatory and non-regulatory cells after expansion of human peripheral blood CD4+ CD25+ cells. Immunol 121: 129-139.
21. Keever-Taylor CA, Browning MB. Johnson BD, Truitt RL, Bredeson CN, Behn B, Tsao A, 2007. Rapamycin enriches for CD4 (+) CD25 (+) CD27 (+) Foxp3 (+) regulatory T cells in ex vivo-expanded CD25-enriched products from healthy donors and patients' with multiple sclerosis. Cytotherapy 9: 144-157.
22. Longhi MS, Hussain MJ, Mitry RR, Arora SK, Mieli-Vergani G, Vergano D, Ma Y, 2006. Functional study of CD4+CD25+ regulatory T cells in health and autoimmune hepatitis. J Immunol 176:4484-4491.
23. Strauss L, Whiteside TL, Knights A, Bergmann C, Knuth A, Zippelius A, 2007. Selective survival of naturally occurring human CD4+CD25+Foxp3+ regulatory T cells cultured with rapamycin. J Immunol 178: 320-329.
24. Valencia X, Yarboro C, Illei G, Lipsky PE, 2007. Deficient CD4+CD25high T regulatory cell function in patients with active systemic lupus erythematosus. J Immunol 178: 25-88.
25. Baecher-Allan C, Brown JA, Freeman GL, Hafler DA, 2001. CD4+CD25 high regulatory cells in human peripheral blood. J Immunol 167:1245-1253.
26. Sumida Y, Nakamura K, Kanayama K, Akiho H, Teshima T, Takayanagi R, 2008. Preparation of functionally preserved CD4+ CD25high regulatory TT cells from leukapheresis products from ulcerative colitis patients, applicable to regulatory T-cell transfer therapy. Cytotherapy 10:698-710.
27. Roederer M, 2001. Spectral compensation for flow cytometry: visualization artifacts, limitations and caveats. Cytometry 45: 194-205.
28. Tung JW, Parks DR, Moore A, Herzenberg LA, Herzenberg AL, 2004. New approaches to fluorescence compensation and visualization of FACS data. Clin Immunol 110: 277-283.
29. Kaushik S, Vajpayee M, Sreenivas V, Pradeep S, 2006. Correlation of T-lymphocyte subpopulations with immunological markers in HIV-l-infected Indian patients. Clin Immunol 119: 330-338.
30. Machura E, Mazur B, Pieniazel W, Karczewska K, 2008. Expression of naive/memory (CD45RA/CD45RO) markers by peripheral blood CD4+ and CD8+ T cells in children with asthma. Arc Immuno Therap Eep 56:55-62.
31. Remoue F, Diallo TO, Angeli V, Herv́ M, deClercq D, Scharcht AM, Charrier N, Capron M, Vercruysse A, Ly A, Capron A, Riveau G, 2003. Malaria coinfection in children influences antibodies response to schistosome antigens and inflammatory markers associated with morbidity. Trans R Soc Trop Med Hyg 97: 361-364.
32. Wilson S, Vennervald BJ. Kadzo H, Ireri E, Amaganga C, Booth M, Kariuki HC, Mwatha JK, Kimani G, Ouma JH, Muchiri E, Dunne DW, 2007. Hepatosplenomegaly in Kenyan schoolchildren: exacerbation by concurrent chronic exposure to malaria and Schistosoma mansoni infection. Trop Med Int Health 12: 1442-1449.
33. Wilson S, Jones FM, Mwatha JK, Kimani G, Booth M, Kariuki HC, Vennervald BJ, Ouma JH, Muchiri E, Dunne DW, 2008. Hepatosplenomegaly is associated with low regulatory and Th2 responses to schistosome antigens in childhood schistosomia- siss and malaria coinfection. Infect Immun 76:2212-2218.