Polyglutamine expansion of huntingtin impairs its nuclear export

Nature Genetics

Volumn 37, Issue 2, 2005, Pages 198-204

  Cornett, Jonathan ^a   Cao, Fengli ^a   Wang, Chuan En ^a   Ross, Christopher A ^b   Bates, Gillian P ^c   Li, Shi Hua ^a   Li, Xiao Jiang ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; HUNTINGTIN; MUTANT PROTEIN; NUCLEOPORIN; POLYGLUTAMINE; RAN PROTEIN; RNA; ONCOPROTEIN; PEPTIDE; TPR PROTEIN, HUMAN;

AMINO TERMINAL SEQUENCE; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; CELL NUCLEUS; CELL STRAIN HEK293; CONTROLLED STUDY; CYTOPLASM; EMBRYO; FEMALE; GENE DELETION; GENE EXPRESSION REGULATION; HELA CELL; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; NUCLEAR PORE; NUCLEOCYTOPLASMIC TRANSPORT; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; RNA INTERFERENCE; AMINO ACID SEQUENCE; CELL CULTURE; CHEMISTRY; GENETIC TRANSFECTION; GENETICS; HUNTINGTON CHOREA; METABOLISM; MOLECULAR GENETICS; MUTATION; PHYSIOLOGY;

ANIMALIA;

AMINO ACID SEQUENCE; CELL NUCLEUS; CELLS, CULTURED; HUMANS; HUNTINGTON DISEASE; MOLECULAR SEQUENCE DATA; MUTATION; NUCLEAR PORE COMPLEX PROTEINS; PEPTIDES; PROMOTER REGIONS (GENETICS); PROTO-ONCOGENE PROTEINS; TRANSFECTION;

EID: 13944275615     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng1503     Document Type: Article

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