Exploring kainate receptor pharmacology using molecular dynamics simulations

Neuropharmacology

Volumn 58, Issue 2, 2010, Pages 515-527

  Postila, Pekka A ^a   Swanson, Geoffrey T ^b   Pentikäinen, Olli T ^a  

^a UNIVERSITY OF JYVÄSKYLÄ   (Finland)

^b NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Agonism; Antagonism; Ionotropic glutamate receptor; Kainate receptor; Molecular dynamics; Partial agonism

Indexed keywords

2,4 EPINEODYSIHERBAINE; 4 EPINEODYSIHERBAINE; 8 DEOXYNEODYSIHERBAINE; 8 EPINEODYSIHERBAINE; 8,9 DIDEOXYNEODYSIHERBAINE; 8,9 EPINEODYSIHERBAINE; 9 DEOXYNEODYSIHERBAINE; 9 EPINEODYSIHERBAINE; 9 FLUORO 8 EPINEODYSIHERBAINE; DOMOIC ACID; DYSIHERBAINE; KAINIC ACID RECEPTOR; KAINIC ACID RECEPTOR AGONIST; KAINIC ACID RECEPTOR ANTAGONIST; LY 466195; NEODYSIHERBAINE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; COMPUTER MODEL; CONTROLLED STUDY; DRUG RECEPTOR BINDING; DRUG STRUCTURE; LIGAND BINDING; MOLECULAR DYNAMICS; MOLECULAR MODEL; PREDICTION; PRIORITY JOURNAL; PROTEIN DOMAIN; REPRODUCIBILITY; STRUCTURE ACTIVITY RELATION;

ALANINE; BICYCLO COMPOUNDS, HETEROCYCLIC; LIGANDS; MARINE TOXINS; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; MOLECULAR STRUCTURE; PROTEIN BINDING; PROTEIN CONFORMATION; RECEPTORS, KAINIC ACID; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 72149121816     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2009.08.019     Document Type: Article

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