Impact of cell type and density on nerve growth factor distribution and bioactivity in 3-dimensional collagen gel cultures

Tissue Engineering

Volumn 12, Issue 7, 2006, Pages 1915-1927

  Mahoney, Melissa J ^a   Krewson, Christine ^b   Miller, Julie ^c   Saltzman, W Mark ^d  

^a UCB 450   (United States)

^b Johns Hopkins University   (United States)

^c Cornell University   (United States)

^d Yale University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN; COLLAGEN; GROWTH KINETICS; MATHEMATICAL MODELS; NEUROLOGY; TOXICITY;

BIOPHYSICAL MODEL; BRAIN TISSUE; COLLAGEN GEL; PROTEIN TRANSPORT;

CELLS;

COLLAGEN GEL; NERVE GROWTH FACTOR;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL DEATH; CELL DENSITY; CELL TYPE; CENTRAL NERVOUS SYSTEM; DIFFUSION; DRUG ACTIVITY; MATHEMATICAL MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY; TISSUE DEGENERATION; TISSUE DISTRIBUTION; TISSUE ENGINEERING;

ANIMALS; BIOLOGICAL TRANSPORT; BRAIN; CELL CULTURE TECHNIQUES; COLLAGEN; DIFFUSION; FETUS; MODELS, BIOLOGICAL; NERVE GROWTH FACTOR; NERVE TISSUE; PC12 CELLS; RATS; TISSUE ENGINEERING;

EID: 33746685619     PISSN: 10763279     EISSN: None     Source Type: Journal    
DOI: 10.1089/ten.2006.12.1915     Document Type: Article

References (51)

1. Lewin, G.R., and Barde, Y.-A. Physiology of the neurotrophins. Ann Rev Neurosci 19, 289, 1996.
2. Morse, J.K., et al. Brain-derived neurotrophic factor (BDNF) prevents the degeneration of medial septal cholinergic neurons following fimbria-fornix transection. J Neurosci 13, 4146, 1993.
3. Burke, M.A., et al. Loss of developing cholinergic basal forebrain neurons following excitotoxic lesions of the hippocampus: rescue by neurotrophins. Exp Neurol 130, 178, 1994.
4. Sinson, G., et al. Improvement of cognitive deficits and decreased cholinergic neuronal cell loss and apoptotic cell death following neurotrophin infusion after experimental traumatic brain injury. J Neurosurg 86, 511, 1997.
5. Wu, D., and Pardridge, W. Neuroprotection with noninvasive neurotrophin delivery to the brain. Proc Natl Acad Sci, USA 96, 254, 1999.
6. Loh, N.K., et al. The regrowth of axons within tissue defects in the CNS is promoted by implanted hydrogel matrices that contain BDNF and CNTF producing fibroblasts. Exp Neurol 170, 72, 2001.
7. Yurek, D.M., et al. BDNF enhances the functional reinnervation of the striatum by grafted fetal dopamine neurons. Exp Neurol 137, 105, 1996.
8. Olson, L., et al. Role of growth factors in degeneration and regeneration in the central nervous system: clinical experience with NGF in Parkinson's and Alzheimer's diseases. J Neurol 241, S12, 1994.
9. Jonhagen, M.E., et al. Intracerebroventricular infusion of nerve growth factor in three patients with Alzheimer's disease. Dement Geriatr Cog Disord 9, 246, 1998.
10. Koliatsos, V.E., Applegate, M.D., and Knusel, B. Recombinant human nerve growth factor prevents retrograde degeneration of axotomized basal forebrain cholinergic neurons in the rat. Exp Neurol 112, 161, 1991.
11. Lapchak, P.A., and Hefti, F. Effect of recombinant human nerve growth factor on presynaptic cholinergic function in rat hippocampal slices following partial septohippocampal lesions: measures of 3Hacetylcholine synthesis, 3Hacetylcholine release and choline acetyltransferase activity. Neuroscience 42, 639, 1991.
12. Tuszynski, M.H., et al. Recombinant human nerve growth factor infusions prevent cholinergic neuronal degeneration in the adult primate brain. Ann Neurol 30, 625, 1991.
13. Olson, L., et al. Intraputaminal infusion of nerve growth factor to support adrenal medullary autografts in Parkinson's disease. Arch Neurol 48, 373, 1991.
14. Poduslo, J.F., Curran, G.L., and Berg, C.T. Macromolecular permeability across the blood-nerve and blood-brain barriers. Proc Natl Acad Sci USA 91, 5705, 1994.
15. Loy, R., et al. Regional CNS uptake of blood-borne nerve growth factor. J Neurosci 39, 339, 1994.
16. Koliatsos, V.E., et al. Human nerve growth factor prevents degeneration of basal forebrain cholinergic neurons in primates. Ann Neurol 30, 831, 1991.
17. Venero, J.L., Hefti, F., and Knusel, B. Trophic effect of exogenous nerve growth factor on rat striatal cholinergic neurons: comparison between intraparenchymal and intraventricular administration. Molec Pharmacol 49, 303, 1996.
18. Ferguson, I.A., et al. Receptor-mediated retrograde transport in CNS neurons after intraventricular administration of NGF and growth factors. J. Compar Neurol 313, 680, 1991.
19. Naumann, T., et al. Is there a long-lasting effect of short-term nerve growth factor application on axotomized rat septohippocampal neurons? Neurosci Lett 173, 213, 1994.
20. Martinez-Serrano, A., and Bjorklund, A. Gene transfer to the mammalian brain: using neural stem cells. Clin Neurosci 3, 301, 1996.
21. Mahoney, M. Controlled release of proteins to tissue transplants for the treatment of neurodegenerative disorders. J Pharm Sci 85, 1276, 1996.
22. Siegel, R., and Langer, R. Controlled release of polypeptides and other macromolecules. Pharm Res 2, 1984.
23. Cohen, S., et al. Controlled delivery systems for proteins based on poly(lacite/glycolic acid) microspheres. Pharm Res 8, 713, 1991.
24. Eldridge, J.H., et al. Biodegradable poly(D,L-lactide-co-glycolide) microspheres. J Control Release 11, 205, 1990.
25. Berkland, C., et al. Precise control of PLG microsphere size provides enhanced control of drug release rate. J Control Release 82, 137, 2002.
26. Sandor, M., et al. Effect of protein molecular weight on release from micron-sized PLGA microspheres. J Control Release 76, 297, 2001.
27. Saltzman, W.M., and Langer, R. Tranport rates of proteins in porous materials with known microgeometry. Biophys J 55, 163, 1989.
28. Mahoney, M.J., and Saltzman, W.M. Controlled release of proteins to tissue transplants for the treatment of neurodegenerative disorders. J Pharm Sci 85, 1276, 1996.
29. Morrison, P., and Dedrick, R. Transport of cisplatin in rat brain following microinfusion: an analysis. J Pharm Sci 75, 120, 1986.
30. Krewson, C.E., and Saltzman, W.M. Distribution of nerve growth factor following direct delivery to the brain interstitium. Brain Res 680, 196, 1995.
31. Krewson, C.E., and Saltzman, W.M. Transport and elimination of recombinant human NGF during long-term delivery to the brain. Brain Res 727, 169, 1996.
32. Mak, M., et al. Distribution of drugs following controlled delivery to the brain interstitium. J Neurooncol 26, 91, 1995.
33. Greene, L. PC12 Pheochromocytoma cultures in neurobiological research. AdvCell Neurobiol 3, 373, 1979.
34. Barker, P.A., and Shooter, E.M. Disruption of NGF binding to the low-affinity neurotrophin receptor p75LNTR reduces NGF binding to trkA on PC12 cells. Neuron 11, 564, 1994.
35. Sobreviela, T., et al. TrkA-Immunoreactive profiles in the central nervous system: colocalization with neurons containing p75 nerve growth factor receptor, choline acetyltransferase, and serotonin. J Compar Neurol 350, 587, 1994.
36. Chao, M.V., and Hempstead, B.L. p75 and trk: A two-receptor system. Trends Neurosci 18, 321, 1995.
37. Mahoney, M.J., and Saltzman, W. Millimeter-scale positioning of a nerve-growth factor source and biological activity in the brain. Proc Natl Acad Sci USA 96, 4536, 1999.
38. Beaty, C.E., and Saltzman W.M. Controlled growth factor delivery induces differential neurite outgrowth in three-dimensional cell cultures. J Control Release 24, 15, 1993.
39. Mahoney, M. Cultures of cells from fetal rat brain: methods to control composition, morphology, and biochemical activity. Biotechnol Bioeng 62, 461, 1999.
40. Hatanaka, H., and Tsukui, H. Differential effects of nerve-growth factor and glioma-conditioned medium on neurons cultured from various regions of fetal rat central nervous system. Developmental Brain Re 30, 47, 1986.
41. Nicholson, C. Diffusion from an injected volume of a substance in brain tissue with arbitrary volume fraction and tortuosity. Brain Res 333, 325, 1985.
42. Nicholson, C. Interaction between diffusion and michaelismenten uptake of dopamine after iontophoresis in striatum. Biophy J 68, 1699, 1995.
43. Nicholson, C., and Sykova, H. Extracellular space structure revealed by diffusion analysis. Trends in Neurosciences 21, 207, 1998.
44. Saltzman, W.M., and Radomsky, M.L. Drugs released from polymers: diffusion and elimination in brain tissue. Chem Eng Sci 46, 2429, 1991.
45. Saltzman, W.M., et al. Antibody diffusion in human cervical mucus. Biophys J 66, 508, 1994.
46. Korbo, L., et al. Total numbers of various cell types in rat cerebellar cortex estimated using an unbiased stereological method. Brain Res 609, 262, 1993.
47. Rusakov, D.A., and Kullmann, D.M. Geometric and viscous components of the tortuosity of the extracellular space in the brain. Proc Natl Acad Sci USA 95, 8975, 1998.
48. Haller, M.F., and Saltzman, W.M. Localized delivery of proteins in the brain: can transport be customized? Pharm Res 15, 377, 1998.
49. Williams, L.R., et al. Continuous infusion of nerve growth factor prevents basal forebrain neuronal death after fimbria fornix transection. Proc Natl Acad Sci USA 83, 9231, 1986.
50. Li, Y., et al. Regulation of TrkA and ChAT expression in developing rat basal forebrain: evidence that both exogenous and endogenous NGF regulate differentiation of cholinergic neurons. J Neurosci 15, 2888, 1995.
51. Krewson, C.E. Controlled Delivery of Growth Factors and Cells for the Treatment of Neurodegenerative Disorders. In: Department of Chemical Engineering. Baltimore: Johns Hopkins University, 1996, p. 312.