Macro-architectures in spinal cord scaffold implants influence regeneration

Journal of Neurotrauma

Volumn 25, Issue 8, 2008, Pages 1027-1037

  Wong, Darice Y ^a   Leveque, Jean Christophe ^b   Brumblay, Hunter ^b   Krebsbach, Paul H ^a   Hollister, Scott J ^a   LaMarca, Frank ^b  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Immunohistochemistry; In vivo studies; Neural injury; Polycaprolactone; Regeneration; Scaffold architecture; Traumatic spinal cord injury

Indexed keywords

BIOLOGICAL FACTOR; FAST BLUE; POLYCAPROLACTONE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY LABELING; ARTICLE; COMPUTER AIDED DESIGN; CONTROLLED STUDY; EXPERIMENTAL RAT; GRAY MATTER; IMPLANT; MORPHOLOGY; NERVE FIBER REGENERATION; NERVOUS TISSUE; NONHUMAN; PRINTING; RAT; SCAR FORMATION; SPINAL CORD; SPINAL CORD SCAFFOLD; SPINAL CORD TRANSSECTION; STAINING; THREE DIMENSIONAL IMAGING;

ANIMALS; BIOCOMPATIBLE MATERIALS; FEMALE; GUIDED TISSUE REGENERATION; POLYESTERS; PROSTHESIS DESIGN; PROSTHESIS IMPLANTATION; RATS; RATS, SPRAGUE-DAWLEY; SPINAL CORD INJURIES; THORACIC VERTEBRAE; TISSUE SCAFFOLDS;

EID: 50149084351     PISSN: 08977151     EISSN: None     Source Type: Journal    
DOI: 10.1089/neu.2007.0473     Document Type: Article

References (49)

1. Bakshi, A., Fisher, O., Daggi, T., Himes, B.T., Fischer, I., and Lowman, A. (2004). Mechanically engineered hydrogel scaffolds for axonal growth and angiogenesis after transplantation in spinal cord injury. J. Neurosurg. 1, 322-329.
2. Barnett, S.C., and Riddell, J.S. (2007). Olfactory ensheathing cell transplantation as a strategy for spinal cord repair - what can it achieve? Nat. Clin. Pract. Neurol. 3, 152-161.
3. Barritt, A.W., Davies, M., Marchand, F., Hartley, R., Grist, J., Yip, P., Mcmahon, S.B., and Bradbury, E.J. (2006). Chondroitinase abc promotes sprouting of intact and injured spinal systems after spinal cord injury. J. Neurosci. 26, 10856-10867.
4. Busch, S.A., and Silver, J. (2007). The role of extracellular matrix in cns regeneration. Curr. Opin. Neurobiol. 17, 120-127.
5. Carone, T.W., and Hasenwinkel, J.M. (2006). Mechanical and morphological characterization of homogeneous and bilayered poly(2-hydroxyethyl methacrylate) scaffolds for use in cns nerve regeneration. J. Biomed. Mater. Res. Part B 78B, 274-282.
6. Clark, P., Connolly, P., Curtis, A.S.G., Dow, J.A.T., and Wilkinson, C.D.W. (1990). Topographical control of cell behavior. 2. Multiple grooved substrata. Development 108, 635-644.
7. Clark, P., Connolly, P., Curtis, A.S.G., Dow, J.A.T., and Wilkinson, C.D.W. (1991). Cell guidance by ultrafine topography in vitro. J. Cell Sci. 99, 73-77.
8. Dinh, P., Bhatia, N., Rasouli, A., Suryadevara, S., Cahill, K., and Gupta, R. (2007). Transplantation of preconditioned Schwann cells following hemisection spinal cord injury. Spine 32, 943-949.
9. El Maarouf, A., Petridis, A.K., and Rutishauser, U. (2006). Use of polysialic acid in repair of the central nervous system. Proc. Natl. Acad. Sci. U.S.A. 103, 16989-16994.
10. Flynn, L., Dalton, P.D., and Shoichet, M.S. (2003). Fiber ternplating of poly(2-hydroxyethyl methacrylate) for neural tissue engineering. Biomaterials 24, 4265-4272.
11. Friedman, J.A., Windebank, A.J., Moore, M.J., Spinner, R.J., Currier, B.L., and Yaszemski, M.J. (2002). Biodegradable polymer grafts for surgical repair of the injured spinal cord. Neurosurgery 51, 742-751.
12. Fukunaga, S., Sasaki, S., Fu, T., Yokoyama, H., Lee, I., Nakagaki, I., Hori, S., Tateishi, H., and Maruo, S. (2004). Experimental study of neural repair of the transected spinal cord using peripheral nerve graft. J. Orthop. Sci. 9, 605-612.
13. Gelain, F., Lomander, A., Vescovi, A.L., and Zhang, S.G. (2007). Systematic studies of a self-assembling peptide nanofiber scaffold with other scaffolds. J. Nanosci. Nanotechnol. 7, 424-434.
14. Goldner, J.S., Bruder, J.M., Li, G., Gazzola, D., and Hoffman-Kim, D. (2006). Neurite bridging across micropatterned grooves. Biomaterials 27, 460-472.
15. Hadlock, T., and Sundback, C. (2006). Biologically inspired approaches to drug delivery for nerve regeneration. Expert Opin. Biol. Ther. 6, 1105-1111.
16. Horn, E.M., Beaumont, M., Shu, X.Z., Harvey, A., Prestwich, G.D., Horn, K.M., Gibson, A.R., Preul, M.C., and Panitch, A. (2007). Influence of cross-linked hyaluronic acid hydrogels on neurite outgrowth and recovery from spinal cord injury. J. Neurosurg. 6, 133-140.
17. Houle, J.D., and Ziegler, M.K. (1994). Bridging a complete transection lesion of adult-rat spinal-cord with growth factor - treated nitrocellulose implants. J. Neural Transplant. Plast. 5, 115-124.
18. Houle, J.D., Tom, V.J., Mayes, D., Wagoner, G., Phillips, N., and Silver, J. (2006). Combining an autologous peripheral nervous system "Bridge" and matrix modification by chondroitinase allows robust, functional regeneration beyond a hemisection lesion of the adult rat spinal cord. J. Neurosci. 26, 7405-7415.
19. Huang, Y.C., Huang, Y.Y., Huang, C.C., and Liu, H.C. (2005). Manufacture of porous polymer nerve conduits through a lyophilizing and wire-heating process. J. Biomed. Mater. Res. Part B 74B, 659-664.
20. Hurtado, A., Moon, L.D.F., Maquet, V., Blits, B., Jerome, R., and Oudega, M. (2006). Poly(D,L-lactic acid) macroporous guidance scaffolds seeded with schwann cells genetically modified to secrete a bi-functional neurotrophin implanted in the completely transected adult rat thoracic spinal cord. Biomaterials 27, 430-442.
21. Ito, Y. (1999). Surface micropatterning to regulate cell functions. Biomaterials 20, 2333-2342.
22. Jones, L.L., Sajed, D., and Tuszynski, M.H. (2003). Axonal regeneration through regions of chondroitin sulfate proteoglycan deposition after spinal cord injury: a balance of permissiveness and inhibition. J. Neurosci. 23, 9276-9288.
23. Kaegi, S., Schwab, M.E., Dietz, V., and Fouad, K. (2002). Electromyographic activity associated with spontaneous functional recovery after spinal cord injury in rats. Eur. J. Neurosci. 16, 249-258.
24. Kuo, H.S., Tsai, M.J., Huang, M.C., Huang, W.C., Lee, M.J., Kuo, W.C., You, L.H., Szeto, K.C., Tsai, I.L., Chang, W.C., Chiu, C.W., Ma, H., Chak, K.F., and Cheng, H. (2007). The combination of peripheral nerve grafts and acidic fibroblast growth factor enhances arginase i and polyamine spermine expression in transected rat spinal cords. Biochem. Biophys. Res. Commun. 357, 1-7.
25. Levi, A.D.O., Dancausse, H., Li, X.M., Duncan, S., Horkey, L., and Oliviera, M. (2002). Peripheral nerve grafts promoting central nervous system regeneration after spinal cord injury in the primate. J. Neurosurg. 96, 197-205.
26. Li, X.G., Yang, Z.Y., and Yang, Y. (2006). Studies on repairing of hemisected thoracic spinal cord of adult rats by using a chitosan tube filled with alginate fibers. Prog. Nat. Sci. 16, 1051-1055.
27. Maier, I.C., and Schwab, M.E. (2006). Sprouting, regeneration and circuit formation in the injured spinal cord: factors and activity. Phil. Trans. R. Soc. B 361, 1611-1634.
28. Miller, C., Jeftinija, S., and Mallapragada, S. (2002). Synergistic effects of physical and chemical guidance cues on neurite alignment and outgrowth on biodegradable polymer substrates. Tissue Eng. 8, 367-378.
29. Mori, S. (1992). Neuronal constituents of postural and locomotor control-systems and their interactions in cats. Brain Dev. 14, S109-S120.
30. Noga, B.R., Kriellaars, D.J., and Jordan, L.M. (1991). The effect of selective brain-stem or spinal-cord lesions on treadmill locomotion evoked by stimulation of the mesencephalic or pontomedullary locomotor regions. J. Neurosci. 11, 1691-1700.
31. Nomura, H., Tator, C.H., and Shoichet, M.S. (2006). Bioengineered strategies for spinal cord repair. J. Neurotrauma 23, 496-507.
32. Nomura, H., Katayama, Y., Shoichet, M.S., and Tator, C.H. (2006). Complete spinal cord transection treated by implantation of a reinforced synthetic hydrogel channel results in syringomyelia and caudal migration of the rostral stump. Neurosurgery 59, 183-192.
33. Novikova, L.N., Novikov, L.N., and Kellerth, J.O. (2003). Biopolymers and biodegradable smart implants for tissue regeneration after spinal cord injury. Curr. Opin. Neurol. 16, 711-715.
34. Oudega, M., Vargas, C.G., Weber, A.B., Kleitman, N., and Bunge, M.B. (1999). Long-term effects of methylprednisolone following transection of adult rat spinal cord. Eur. J. Neurosci. 11, 2453-2464.
35. Oudega, M., Gautier, S.E., Chapon, P., Fragoso, M., Bates, M.L., Parel, J.M., and Bunge, M.B. (2001). Axonal regeneration into schwann cell grafts within resorbable poly(alpha-hydroxy-acid) guidance channels in the adult rat spinal cord. Biomaterials 22, 1125-1136.
36. Patist, C.M., Mulder, M.B., Gautier, S.E., Maquet, V., Jerome, R., and Oudega, M. (2004). Freeze-dried poly(D,L-lactic acid) macroporous guidance scaffolds impregnated with brain-derived neurotrophic factor in the transected adult rat thoracic spinal cord. Biomaterials 25, 1569-1582.
37. Schucht, P., Raineteau, O., Schwab, M.E., and Fouad, K. (2002). Anatomical correlates of locomotor recovery following dorsal and ventral lesions of the rat spinal cord. Exp. Neurol. 176, 143-153.
38. Schwab, J.M., Brechtel, K., Mueller, C.A., Failli, V., Kaps, H.P., Tuli, S.K., and Schluesener, H.J. (2006). Experimental strategies to promote spinal cord regeneration - an integrative perspective. Prog. Neurobiol. 78, 91-116.
39. Schwab, M.E. (2002). Repairing the injured spinal cord. Science 295, 1029-1031.
40. Stokols, S., Sakamoto, J., Breckon, C., Holt, T., Weiss, J., and Tuszynski, M.H. (2006). Templated agarose scaffolds support linear axonal regeneration. Tissue Eng. 12, 2777-2787.
41. Tate, M.C., Shear, D.A., Hoffman, S.W., Stein, D.G., Archer, D.R., and Laplaca, M.C. (2002). Fibronectin promotes survival and migration of primary neural stem cells transplanted into the traumatically injured mouse brain. Cell Transplant. 11, 283-295.
42. Teng, Y.D., Lavik, E.B., Qu, X.L., Park, K.I., Ourednik, J., Zurakowski, D., Langer, R., and Snyder, E.Y. (2002). Functional recovery following traumatic spinal cord injury mediated by a unique polymer scaffold seeded with neural stem cells. Proc. Natl. Acad. Sci. U.S.A. 99, 3024-3029.
43. Thoenen, H. (1991). The changing scene of neurotrophic factors. Trends Neurosci. 14, 165-170.
44. Tsai, E.C., Dalton, P.D., Shoichet, M.S., and Tator, C.H. (2004). Synthetic hydrogel guidance channels facilitate regeneration of adult rat brainstem motor axons after complete spinal cord transection. J. Neurotrauma 21, 789-804.
45. Tsai, E.C., Dalton, P.D., Shoichet, M.S., and Tator, C.H. (2006). Matrix inclusion within synthetic hydrogel guidance channels improves specific supraspinal and local axonal regeneration after complete spinal cord transection. Biomaterials 27, 519-533.
46. Wong, D.Y., Hollister, S.J., Krebsbach, P.H., and Nosrat, C. (2007). Pcl and plga degradable polymer sponges attenuate astrocyte response and lesion growth in acute traumatic brain injury. Tissue Eng. 13, 2515-2523.
47. Yoshii, S., Oka, M., Shima, M., Akagi, M., and Taniguchi, A. (2003). Bridging a spinal cord defect using collagen filament. Spine 28, 2346-2351.
48. Yoshii, S., Oka, M., Shima, M., Taniguchi, A., Taki, Y., and Akagi, M. (2004). Restoration of function after spinal cord transection using a collagen bridge. J. Biomed. Mater. Res. Part A 70A, 569-575.
49. Zhang, N., Yan, H.H., and Wen, X.J. (2005). Tissue-engineering approaches for axonal guidance. Brain Res. Rev. 49, 48-64.