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Volumn 9, Issue 11, 2009, Pages 1631-1642

Dendritic cell vaccination as a treatment modality for melanoma

Author keywords

Cancer immunotherapy; Cancer vaccination; Dendritic cell; Melanoma

Indexed keywords

ALPHA INTERFERON; ALPHA2A INTERFERON; ALPHA2B INTERFERON; BCG VACCINE; COMPLEMENTARY DNA; CPG OLIGODEOXYNUCLEOTIDE; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4 ANTIBODY; DACARBAZINE; DENDRITIC CELL VACCINE; DENILEUKIN DIFTITOX; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HLA ANTIGEN; IMIQUIMOD; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 6; IPILIMUMAB; MAJOR HISTOCOMPATIBILITY ANTIGEN; MELAN A; MELANOMA ANTIGEN 1; MELANOMA ANTIGEN 3; MELANOMA VACCINE; MESSENGER RNA; PEPTIDE VACCINE; TOLL LIKE RECEPTOR AGONIST; TUMOR ANTIGEN; TUMOR NECROSIS FACTOR ALPHA; TUMOR VACCINE; UNINDEXED DRUG;

EID: 71949123992     PISSN: 14737140     EISSN: 17448328     Source Type: Journal    
DOI: 10.1586/ERA.09.139     Document Type: Review
Times cited : (20)

References (124)
  • 2
    • 57349094378 scopus 로고    scopus 로고
    • Recent trends in incidence of cutaneous melanoma among US Caucasian young adults
    • Purdue MP, Freeman LE, Anderson WF, Tucker MA. Recent trends in incidence of cutaneous melanoma among US Caucasian young adults. J. Invest. Dermatol. 128(12), 2905-2908 (2008).
    • (2008) J. Invest. Dermatol. , vol.128 , Issue.12 , pp. 2905-2908
    • Purdue, M.P.1    Freeman, L.E.2    Anderson, W.F.3    Tucker, M.A.4
  • 3
    • 33749064973 scopus 로고    scopus 로고
    • Trends in sunburns, sun protection practices, and attitudes toward sun exposure protection and tanning among US adolescents, 1998-2004
    • Cokkinides V, Weinstock M, Glanz K, Albano J, Ward E, Thun M. Trends in sunburns, sun protection practices, and attitudes toward sun exposure protection and tanning among US adolescents, 1998-2004. Pediatrics 118(3), 853-864 (2006).
    • (2006) Pediatrics , vol.118 , Issue.3 , pp. 853-864
    • Cokkinides, V.1    Weinstock, M.2    Glanz, K.3    Albano, J.4    Ward, E.5    Thun, M.6
  • 4
    • 11144286045 scopus 로고    scopus 로고
    • Indoor tanning by adolescents: Prevalence, practices and policies
    • DOI 10.1016/j.ejca.2004.09.015, PII S0959804904007609
    • Lazovich D, Forster J. Indoor tanning by adolescents: prevalence, practices and policies. Eur. J. Cancer 41(1), 20-27 (2005). (Pubitemid 40029656)
    • (2005) European Journal of Cancer , vol.41 , Issue.1 , pp. 20-27
    • Lazovich, D.1    Forster, J.2
  • 5
    • 33846805780 scopus 로고    scopus 로고
    • The association of use of sunbeds with cutaneous malignant melanoma and other skin cancers: A systematic review
    • International Agency for Research on Cancer Working Group on artificial ultraviolet (UV) light and skin cancer.
    • International Agency for Research on Cancer Working Group on artificial ultraviolet (UV) light and skin cancer. The association of use of sunbeds with cutaneous malignant melanoma and other skin cancers: a systematic review. Int. J. Cancer 120(5), 1116-1122 (2007).
    • (2007) Int. J. Cancer , vol.120 , Issue.5 , pp. 1116-1122
  • 6
    • 59549083657 scopus 로고    scopus 로고
    • Primary melanomas of the esophagus and anorectum: Epidemiologic comparison with melanoma of the skin
    • Cote TR, Sobin LH. Primary melanomas of the esophagus and anorectum: epidemiologic comparison with melanoma of the skin. Melanoma Res. 19(1), 58-60 (2009).
    • (2009) Melanoma Res. , vol.19 , Issue.1 , pp. 58-60
    • Cote, T.R.1    Sobin, L.H.2
  • 7
    • 33645530701 scopus 로고    scopus 로고
    • Light during darkness and cancer: Relationships in circadian photoreception and tumor biology
    • Jasser SA, Blask DE, Brainard GC. Light during darkness and cancer: relationships in circadian photoreception and tumor biology. Cancer Causes Control 17(4), 515-523 (2006).
    • (2006) Cancer Causes Control , vol.17 , Issue.4 , pp. 515-523
    • Jasser, S.A.1    Blask, D.E.2    Brainard, G.C.3
  • 8
    • 0029065312 scopus 로고
    • Primary cutaneous melanoma. Identification of prognostic groups and estimation of individual prognosis for 5093 patients
    • Garbe C, Buttner P, Bertz J et al. Primary cutaneous melanoma. Identification of prognostic groups and estimation of individual prognosis for 5093 patients. Cancer 75(10), 2484-2491 (1995).
    • (1995) Cancer , vol.75 , Issue.10 , pp. 2484-2491
    • Garbe, C.1    Buttner, P.2    Bertz, J.3
  • 9
    • 0347503603 scopus 로고    scopus 로고
    • Palliative therapy of disseminated malignant melanoma: A systematic review of 41 randomised clinical trials
    • DOI 10.1016/S1470-2045(03)01280-4
    • Eigentler TK, Caroli UM, Radny P, Garbe C. Palliative therapy of disseminated malignant melanoma: a systematic review of 41 randomised clinical trials. Lancet Oncol. 4(12), 748-759 (2003). (Pubitemid 37527210)
    • (2003) Lancet Oncology , vol.4 , Issue.12 , pp. 748-759
    • Eigentler, T.K.1    Caroli, U.M.2    Radny, P.3    Garbe, C.4
  • 10
    • 0035880957 scopus 로고    scopus 로고
    • Prognostic factors analysis of 17,600 melanoma patients: Validation of the American Joint Committee on Cancer melanoma staging system
    • Balch CM, Soong SJ, Gershenwald JE et al. Prognostic factors analysis of 17,600 melanoma patients: validation of the American Joint Committee on Cancer melanoma staging system. J. Clin. Oncol. 19(16), 3622-3634 (2001).
    • (2001) J. Clin. Oncol. , vol.19 , Issue.16 , pp. 3622-3634
    • Balch, C.M.1    Soong, S.J.2    Gershenwald, J.E.3
  • 12
    • 0017096667 scopus 로고
    • Spontaneous regression of malignant melanoma: A review of the literature on incidence, clinical features, and possible mechanisms
    • Nathanson. Spontaneous regression of malignant melanoma: a review of the literature on incidence, clinical features, and possible mechanisms. Natl Cancer Inst. Monogr. 44, 67-76 (1976).
    • (1976) Natl Cancer Inst. Monogr. , vol.44 , pp. 67-76
    • Nathanson1
  • 14
    • 0041409703 scopus 로고    scopus 로고
    • Does adjuvant interferon-α for high-risk melanoma provide a worthwhile benefit? a meta-analysis of the randomised trials
    • DOI 10.1016/S0305-7372(03)00074-4
    • Wheatley K, Ives N, Hancock B, Gore M, Eggermont A, Suciu S. Does adjuvant interferon-α for high-risk melanoma provide a worthwhile benefit? A metaanalysis of the randomised trials. Cancer Treat. Rev. 29(4), 241-252 (2003). (Pubitemid 37069655)
    • (2003) Cancer Treatment Reviews , vol.29 , Issue.4 , pp. 241-252
    • Wheatley, K.1    Ives, N.2    Hancock, B.3    Gore, M.4    Eggermont, A.5    Suciu, S.6
  • 15
    • 58149138892 scopus 로고    scopus 로고
    • Adjuvant therapy of melanoma with interferon: Lessons of the past decade
    • Ascierto PA, Kirkwood JM. Adjuvant therapy of melanoma with interferon: lessons of the past decade. J. Transl. Med. 6, 62 (2008).
    • (2008) J. Transl. Med. , vol.6 , pp. 62
    • Ascierto, P.A.1    Kirkwood, J.M.2
  • 16
    • 0030030347 scopus 로고    scopus 로고
    • Interferon α-2b adjuvant therapy of high-risk resected cutaneous melanoma: The Eastern Cooperative Oncology Group Trial EST 1684
    • Kirkwood JM, Strawderman MH, Ernstoff MS, Smith TJ, Borden EC, Blum RH. Interferon α-2b adjuvant therapy of high-risk resected cutaneous melanoma: the Eastern Cooperative Oncology Group Trial EST 1684. J. Clin. Oncol. 14(1), 7-17 (1996).
    • (1996) J. Clin. Oncol. , vol.14 , Issue.1 , pp. 7-17
    • Kirkwood, J.M.1    Strawderman, M.H.2    Ernstoff, M.S.3    Smith, T.J.4    Borden, E.C.5    Blum, R.H.6
  • 17
    • 0034088027 scopus 로고    scopus 로고
    • High- and low-dose interferon α-2b in high-risk melanoma: First analysis of intergroup trial E1690/S9111/C9190
    • Kirkwood JM, Ibrahim JG, Sondak VK et al. High- and low-dose interferon α-2b in high-risk melanoma: first analysis of intergroup trial E1690/S9111/C9190. J. Clin. Oncol. 18(12), 2444-2458 (2000).
    • (2000) J. Clin. Oncol. , vol.18 , Issue.12 , pp. 2444-2458
    • Kirkwood, J.M.1    Ibrahim, J.G.2    Sondak, V.K.3
  • 18
    • 0035339880 scopus 로고    scopus 로고
    • High-dose interferon α-2b significantly prolongs relapse-free and overall survival compared with the GM2-KLH/QS-21 vaccine in patients with resected stage IIB-III melanoma: Results of intergroup trial E1694/S9512/C509801
    • Kirkwood JM, Ibrahim JG, Sosman JA et al. High-dose interferon α-2b significantly prolongs relapse-free and overall survival compared with the GM2-KLH/QS-21 vaccine in patients with resected stage IIB-III melanoma: results of intergroup trial E1694/S9512/C509801. J. Clin. Oncol. 19(9), 2370-2380 (2001).
    • (2001) J. Clin. Oncol. , vol.19 , Issue.9 , pp. 2370-2380
    • Kirkwood, J.M.1    Ibrahim, J.G.2    Sosman, J.A.3
  • 20
    • 35649015750 scopus 로고    scopus 로고
    • Interferon-α as adjuvant therapy for melanoma: An individual patient data meta-analysis of randomised trials
    • Wheatley K, Ives N, Eggermont A et al. Interferon-α as adjuvant therapy for melanoma: an individual patient data meta-analysis of randomised trials. Proc. Am. Soc. Clin. Oncol. 25, 478S (2007).
    • (2007) Proc. Am. Soc. Clin. Oncol. , vol.25
    • Wheatley, K.1    Ives, N.2    Eggermont, A.3
  • 21
    • 0033024863 scopus 로고    scopus 로고
    • High-dose recombinant interleukin 2 therapy for patients with metastatic melanoma: Analysis of 270 patients treated between 1985 and 1993
    • Atkins MB, Lotze MT, Dutcher JP et al. High-dose recombinant interleukin 2 therapy for patients with metastatic melanoma: analysis of 270 patients treated between 1985 and 1993. J. Clin. Oncol. 17(7), 2105-2116 (1999).
    • (1999) J. Clin. Oncol. , vol.17 , Issue.7 , pp. 2105-2116
    • Atkins, M.B.1    Lotze, M.T.2    Dutcher, J.P.3
  • 22
    • 0028266553 scopus 로고
    • Treatment of 283 consecutive patients with metastatic melanoma or renal cell cancer using high-dose bolus interleukin 2
    • Rosenberg SA, Yang JC, Topalian SL et al. Treatment of 283 consecutive patients with metastatic melanoma or renal cell cancer using high-dose bolus interleukin 2. JAMA 271(12), 907-913 (1994).
    • (1994) JAMA , vol.271 , Issue.12 , pp. 907-913
    • Rosenberg, S.A.1    Yang, J.C.2    Topalian, S.L.3
  • 24
    • 67449138506 scopus 로고    scopus 로고
    • Autoimmune antibodies and recurrence-free interval in melanoma patients treated with adjuvant interferon
    • Bouwhuis MG, Suciu S, Collette S et al. Autoimmune antibodies and recurrence-free interval in melanoma patients treated with adjuvant interferon. J. Natl Cancer Inst. 101(12), 869-877 (2009).
    • (2009) J. Natl Cancer Inst. , vol.101 , Issue.12 , pp. 869-877
    • Bouwhuis, M.G.1    Suciu, S.2    Collette, S.3
  • 25
    • 1842582038 scopus 로고    scopus 로고
    • Mature Results of a Phase III Randomized Trial of Bacillus Calmette-Guerin (BCG) versus Observation and BCG plus Dacarbazine versus BCG in the Adjuvant Therapy of American Joint Committee on Cancer Stage I-III Melanoma (E1673): A Trial of the Eastern Cooperative Oncology Group
    • DOI 10.1002/cncr.20166
    • Agarwala SS, Neuberg D, Park Y, Kirkwood JM. Mature results of a Phase III randomized trial of bacillus Calmette- Guerin (BCG) versus observation and BCG plus dacarbazine versus BCG in the adjuvant therapy of American Joint Committee on Cancer stage I-III melanoma (E1673): a trial of the Eastern Oncology Group. Cancer 100(8), 1692-1698 (2004). (Pubitemid 38456347)
    • (2004) Cancer , vol.100 , Issue.8 , pp. 1692-1698
    • Agarwala, S.S.1    Neuberg, D.2    Park, Y.3    Kirkwood, J.M.4
  • 26
    • 33846212288 scopus 로고    scopus 로고
    • Phase I/II study of topical imiquimod and intralesional interleukin-2 in the treatment of accessible metastases in malignant melanoma
    • Green DS, Bodman-Smith MD, Dalgleish AG, Fischer MD. Phase I/II study of topical imiquimod and intralesional interleukin-2 in the treatment of accessible metastases in malignant melanoma. Br. J. Dermatol. 156(2), 337-345 (2007).
    • (2007) Br. J. Dermatol. , vol.156 , Issue.2 , pp. 337-345
    • Green, D.S.1    Bodman-Smith, M.D.2    Dalgleish, A.G.3    Fischer, M.D.4
  • 27
    • 49749143414 scopus 로고    scopus 로고
    • Topical imiquimod and intralesional interleukin-2 increase activated lymphocytes and restore the Th1/Th2 balance in patients with metastatic melanoma
    • Green DS, Dalgleish AG, Belonwu N, Fischer MD, Bodman-Smith MD. Topical imiquimod and intralesional interleukin-2 increase activated lymphocytes and restore the Th1/Th2 balance in patients with metastatic melanoma. Br. J. Dermatol. 159(3), 606-614 (2008).
    • (2008) Br. J. Dermatol. , vol.159 , Issue.3 , pp. 606-614
    • Green, D.S.1    Dalgleish, A.G.2    Belonwu, N.3    Fischer, M.D.4    Bodman-Smith, M.D.5
  • 28
    • 61449090474 scopus 로고    scopus 로고
    • Phase I/II trial of tremelimumab in patients with metastatic melanoma
    • Camacho LH, Antonia S, Sosman J et al. Phase I/II trial of tremelimumab in patients with metastatic melanoma. J. Clin. Oncol. 27(7), 1075-1081 (2009).
    • (2009) J. Clin. Oncol. , vol.27 , Issue.7 , pp. 1075-1081
    • Camacho, L.H.1    Antonia, S.2    Sosman, J.3
  • 29
    • 58049202334 scopus 로고    scopus 로고
    • Phase I/II study of ipilimumab for patients with metastatic melanoma
    • Weber JS, O'Day S, Urba W et al. Phase I/II study of ipilimumab for patients with metastatic melanoma. J. Clin. Oncol. 26(36), 5950-5956 (2008).
    • (2008) J. Clin. Oncol. , vol.26 , Issue.36 , pp. 5950-5956
    • Weber, J.S.1    O'Day, S.2    Urba, W.3
  • 30
    • 34848837386 scopus 로고    scopus 로고
    • Taking dendritic cells into medicine
    • Review on the use of dendritic cells (DCs) in medicine
    • Steinman RM, Banchereau J. Taking dendritic cells into medicine. Nature 449(7161), 419-426 (2007). • Review on the use of dendritic cells (DCs) in medicine.
    • (2007) Nature , vol.449 , Issue.7161 , pp. 419-426
    • Steinman, R.M.1    Banchereau, J.2
  • 32
    • 0029024915 scopus 로고
    • Antigen capture and major histocompatibility class II compartments of freshly isolated and cultured human blood dendritic cells
    • Nijman HW, Kleijmeer MJ, Ossevoort MA et al. Antigen capture and major histocompatibility class II compartments of freshly isolated and cultured human blood dendritic cells. J. Exp. Med. 182(1), 163-174 (1995).
    • (1995) J. Exp. Med. , vol.182 , Issue.1 , pp. 163-174
    • Nijman, H.W.1    Kleijmeer, M.J.2    Ossevoort, M.A.3
  • 35
    • 0036668249 scopus 로고    scopus 로고
    • Interactions between dead cells and dendritic cells in the induction of antiviral CTL responses
    • DOI 10.1016/S0952-7915(02)00358-8
    • Fonteneau JF, Larsson M, Bhardwaj N. Interactions between dead cells and dendritic cells in the induction of antiviral CTL responses. Curr. Opin. Immunol. 14(4), 471-477 (2002). (Pubitemid 34671250)
    • (2002) Current Opinion in Immunology , vol.14 , Issue.4 , pp. 471-477
    • Fonteneau, J.-F.1    Larsson, M.2    Bhardwaj, N.3
  • 36
    • 0141707939 scopus 로고    scopus 로고
    • ER-phagosome fusion defines an MHC class I cross-presentation compartment in dendritic cells
    • DOI 10.1038/nature01911
    • Guermonprez P, Saveanu L, Kleijmeer M, Davoust J, Van Endert P, Amigorena S. ER-phagosome fusion defines an MHC class I cross-presentation compartment in dendritic cells. Nature 425(6956), 397-402 (2003). (Pubitemid 37187268)
    • (2003) Nature , vol.425 , Issue.6956 , pp. 397-402
    • Guermonprez, P.1    Saveanu, L.2    Kleijmeer, M.3    Davoust, J.4    Van Endert, P.5    Amigorena, S.6
  • 37
    • 32944464648 scopus 로고    scopus 로고
    • Pathogen recognition and innate immunity
    • Akira S, Uematsu S, Takeuchi O. Pathogen recognition and innate immunity. Cell 124(4), 783-801 (2006).
    • (2006) Cell , vol.124 , Issue.4 , pp. 783-801
    • Akira, S.1    Uematsu, S.2    Takeuchi, O.3
  • 38
    • 0037066427 scopus 로고    scopus 로고
    • The danger model: A renewed sense of self
    • DOI 10.1126/science.1071059
    • Matzinger P. The danger model: a renewed sense of self. Science 296(5566), 301-305 (2002). (Pubitemid 34303674)
    • (2002) Science , vol.296 , Issue.5566 , pp. 301-305
    • Matzinger, P.1
  • 39
    • 5444262511 scopus 로고    scopus 로고
    • Toll-like receptor control of the adaptive immune responses
    • DOI 10.1038/ni1112
    • Iwasaki A, Medzhitov R. Toll-like receptor control of the adaptive immune responses. Nat. Immunol. 5(10), 987-995 (2004). (Pubitemid 41057715)
    • (2004) Nature Immunology , vol.5 , Issue.10 , pp. 987-995
    • Iwasaki, A.1    Medzhitov, R.2
  • 40
    • 0036607954 scopus 로고    scopus 로고
    • CD83 on dendritic cells: More than just a marker for maturation
    • DOI 10.1016/S1471-4906(02)02214-7, PII S1471490602022147
    • Lechmann M, Berchtold S, Hauber J, Steinkasserer A. CD83 on dendritic cells: more than just a marker for maturation. Trends Immunol. 23(6), 273-275 (2002). (Pubitemid 34628763)
    • (2002) Trends in Immunology , vol.23 , Issue.6 , pp. 273-275
    • Lechmann, M.1    Berchtold, S.2    Steinkasserer, A.3    Hauber, J.4
  • 41
    • 0029148878 scopus 로고
    • Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: Downregulation by cytokines and bacterial products
    • Sallusto F, Cella M, Danieli C, Lanzavecchia A. Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: downregulation by cytokines and bacterial products. J. Exp. Med. 182(2), 389-400 (1995).
    • (1995) J. Exp. Med. , vol.182 , Issue.2 , pp. 389-400
    • Sallusto, F.1    Cella, M.2    Danieli, C.3    Lanzavecchia, A.4
  • 42
    • 0032482274 scopus 로고    scopus 로고
    • Immunology. Licence to kill
    • Lanzavecchia A. Immunology. Licence to kill. Nature 393(6684), 413-414 (1998).
    • (1998) Nature , vol.393 , Issue.6684 , pp. 413-414
    • Lanzavecchia, A.1
  • 44
    • 0037501371 scopus 로고    scopus 로고
    • + T cell priming by dendritic cells in intact lymph nodes
    • + T cell priming by dendritic cells in intact lymph nodes. Nat. Immunol. 4(6), 579-585 (2003).
    • (2003) Nat. Immunol. , vol.4 , Issue.6 , pp. 579-585
    • Bousso, P.1    Robey, E.2
  • 45
    • 65049087020 scopus 로고    scopus 로고
    • Myeloid dendritic cell: From sentinel of immunity to key player of peripheral tolerance?
    • Steinbrink K, Mahnke K, Grabbe S, Enk AH, Jonuleit H. Myeloid dendritic cell: from sentinel of immunity to key player of peripheral tolerance? Hum. Immunol. 70(5), 289-293 (2009).
    • (2009) Hum. Immunol. , vol.70 , Issue.5 , pp. 289-293
    • Steinbrink, K.1    Mahnke, K.2    Grabbe, S.3    Enk, A.H.4    Jonuleit, H.5
  • 46
    • 0030769146 scopus 로고    scopus 로고
    • High levels of a major histocompatibility complex II-self peptide complex on dendritic cells from the T cell areas of lymph nodes
    • DOI 10.1084/jem.186.5.665
    • Inaba K, Pack M, Inaba M, Sakuta H, Isdell F, Steinman RM. High levels of a major histocompatibility complex II-self peptide complex on dendritic cells from the T cell areas of lymph nodes. J. Exp. Med. 186(5), 665-672 (1997). (Pubitemid 27381531)
    • (1997) Journal of Experimental Medicine , vol.186 , Issue.5 , pp. 665-672
    • Inaba, K.1    Pack, M.2    Inaba, M.3    Sakuta, H.4    Isdell, F.5    Steinman, R.M.6
  • 50
    • 0031941423 scopus 로고    scopus 로고
    • Vaccination of melanoma patients with peptide- Or tumor lysate-pulsed dendritic cells
    • DOI 10.1038/nm0398-328
    • Nestle FO, Alijagic S, Gilliet M et al. Vaccination of melanoma patients with peptide- or tumor lysate-pulsed dendritic cells. Nat. Med. 4(3), 328-332 (1998). • First study on DC-based vaccination in stage IV melanoma patients. (Pubitemid 28144092)
    • (1998) Nature Medicine , vol.4 , Issue.3 , pp. 328-332
    • Nestle, F.O.1    Alijagic, S.2    Gilliet, M.3    Sun, Y.4    Grabbe, S.5    Dummer, R.6    Burg, G.7    Schadendorf, D.8
  • 53
    • 0035953308 scopus 로고    scopus 로고
    • IFNγ, and lymphocytes prevent primary tumour development and shape tumour immunogenicity
    • DOI 10.1038/35074122
    • Shankaran V, Ikeda H, Bruce AT et al. IFNγ and lymphocytes prevent primary tumour development and shape tumour immunogenicity. Nature 410(6832), 1107-1111 (2001). (Pubitemid 32391043)
    • (2001) Nature , vol.410 , Issue.6832 , pp. 1107-1111
    • Shankaran, V.1    Ikeda, H.2    Bruce, A.T.3    White, J.M.4    Swanson, P.E.5    Old, L.J.6    Schreiber, R.D.7
  • 54
    • 0041831040 scopus 로고    scopus 로고
    • Update on non-acquired immunodeficiency syndrome-defining malignancies
    • Chiao EY, Krown SE. Update on non-acquired immunodeficiency syndrome-defining malignancies. Curr. Opin. Oncol. 15(5), 389-397 (2003).
    • (2003) Curr. Opin. Oncol. , vol.15 , Issue.5 , pp. 389-397
    • Chiao, E.Y.1    Krown, S.E.2
  • 56
    • 33645325115 scopus 로고    scopus 로고
    • Dacarbazine (DTIC) versus vaccination with autologous peptide-pulsed dendritic cells (DC) in first-line treatment of patients with metastatic melanoma: A randomized Phase III trial of the DC study group of the DeCOG
    • The largest Phase III clinical trial comparing DC-based vaccination with standard dacarbazine chemotherapy in stage IV melanoma patients
    • Schadendorf D, Ugurel S, Schuler-Thurner B et al. Dacarbazine (DTIC) versus vaccination with autologous peptide-pulsed dendritic cells (DC) in first-line treatment of patients with metastatic melanoma: a randomized Phase III trial of the DC study group of the DeCOG. Ann. Oncol. 17(4), 563-570 (2006). • The largest Phase III clinical trial comparing DC-based vaccination with standard dacarbazine chemotherapy in stage IV melanoma patients.
    • (2006) Ann. Oncol. , vol.17 , Issue.4 , pp. 563-570
    • Schadendorf, D.1    Ugurel, S.2    Schuler-Thurner, B.3
  • 58
    • 0037089672 scopus 로고    scopus 로고
    • Adjuvant immunotherapy of resected, intermediate-thickness, node-negative melanoma with an allogeneic tumor vaccine: Impact of HLA class I antigen expression on outcome
    • Sosman JA, Unger JM, Liu PY et al. Adjuvant immunotherapy of resected, intermediate-thickness, node-negative melanoma with an allogeneic tumor vaccine: impact of HLA class I antigen expression on outcome. J. Clin. Oncol. 20(8), 2067-2075 (2002).
    • (2002) J. Clin. Oncol. , vol.20 , Issue.8 , pp. 2067-2075
    • Sosman, J.A.1    Unger, J.M.2    Liu, P.Y.3
  • 60
    • 0642311904 scopus 로고    scopus 로고
    • Clinical and immunologic results of a randomized Phase II trial of vaccination using four melanoma peptides either administered in granulocyte-macrophage colony-stimulating factor in adjuvant or pulsed on dendritic cells
    • Slingluff CL Jr, Petroni GR, Yamshchikov GV et al. Clinical and immunologic results of a randomized Phase II trial of vaccination using four melanoma peptides either administered in granulocyte-macrophage colony-stimulating factor in adjuvant or pulsed on dendritic cells. J. Clin. Oncol. 21(21), 4016-4026 (2003).
    • (2003) J. Clin. Oncol. , vol.21 , Issue.21 , pp. 4016-4026
    • Slingluff Jr., C.L.1    Petroni, G.R.2    Yamshchikov, G.V.3
  • 61
    • 33646419816 scopus 로고    scopus 로고
    • Induction of strong and persistent MelanA/MART-1-specific immune responses by adjuvant dendritic cell-based vaccination of stage II melanoma patients
    • DC-based vaccination study performed in stage II melanoma patients
    • Tuettenberg A, Becker C, Huter E, Knop J, Enk AH, Jonuleit H. Induction of strong and persistent MelanA/MART-1-specific immune responses by adjuvant dendritic cell-based vaccination of stage II melanoma patients. Int. J. Cancer 118(10), 2617-2627 (2006). • DC-based vaccination study performed in stage II melanoma patients.
    • (2006) Int. J. Cancer , vol.118 , Issue.10 , pp. 2617-2627
    • Tuettenberg, A.1    Becker, C.2    Huter, E.3    Knop, J.4    Enk, A.H.5    Jonuleit, H.6
  • 62
    • 61949105112 scopus 로고    scopus 로고
    • Peripheral blood lymphocytes genetically modified to express the self/tumor antigen MAGE-A3 induce anti-tumor immune responses in cancer patients
    • Fontana R, Bregni M, Cipponi A et al. Peripheral blood lymphocytes genetically modified to express the self/tumor antigen MAGE-A3 induce anti-tumor immune responses in cancer patients. Blood 113(8), 1651-1660 (2009).
    • (2009) Blood , vol.113 , Issue.8 , pp. 1651-1660
    • Fontana, R.1    Bregni, M.2    Cipponi, A.3
  • 63
    • 10744224631 scopus 로고    scopus 로고
    • Maturation of dendritic cells is a prerequisite for inducing immune responses in advanced melanoma patients
    • de Vries IJ, Lesterhuis WJ, Scharenborg NM et al. Maturation of dendritic cells is a prerequisite for inducing immune responses in advanced melanoma patients. Clin. Cancer Res. 9(14), 5091-5100 (2003).
    • (2003) Clin. Cancer Res. , vol.9 , Issue.14 , pp. 5091-5100
    • De Vries, I.J.1    Lesterhuis, W.J.2    Scharenborg, N.M.3
  • 65
    • 10144260007 scopus 로고    scopus 로고
    • + hematopoietic progenitors from human cord blood differentiate along two independent dendritic cell pathways in response to GM-CSF + TNF α
    • + hematopoietic progenitors from human cord blood differentiate along two independent dendritic cell pathways in response to GM-CSF + TNF α. J. Exp. Med. 184(2), 695-706 (1996).
    • (1996) J. Exp. Med. , vol.184 , Issue.2 , pp. 695-706
    • Caux, C.1    Vanbervliet, B.2    Massacrier, C.3
  • 66
    • 0028289244 scopus 로고
    • Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor α
    • Sallusto F, Lanzavecchia A. Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colonystimulating factor plus interleukin 4 and downregulated by tumor necrosis factor α. J. Exp. Med. 179(4), 1109-1118 (1994). (Pubitemid 24091769)
    • (1994) Journal of Experimental Medicine , vol.179 , Issue.4 , pp. 1109-1118
    • Sallusto, F.1    Lanzavecchia, A.2
  • 67
    • 0026512117 scopus 로고
    • Development of a Langerhans cell phenotype from peripheral blood monocytes
    • Rossi G, Heveker N, Thiele B, Gelderblom H, Steinbach F. Development of a Langerhans cell phenotype from peripheral blood monocytes. Immunol. Lett. 31(2), 189-197 (1992).
    • (1992) Immunol. Lett. , vol.31 , Issue.2 , pp. 189-197
    • Rossi, G.1    Heveker, N.2    Thiele, B.3    Gelderblom, H.4    Steinbach, F.5
  • 69
    • 2642631750 scopus 로고    scopus 로고
    • Pro-inflammatory cytokines and prostaglandins induce maturation of potent immunostimulatory dendritic cells under fetal calf serum-free conditions
    • DOI 10.1002/eji.1830271209
    • Jonuleit H, Kuhn U, Muller G et al. Pro-inflammatory cytokines and prostaglandins induce maturation of potent immunostimulatory dendritic cells under fetal calf serum-free conditions. Eur. J. Immunol. 27(12), 3135-3142 (1997). (Pubitemid 28018007)
    • (1997) European Journal of Immunology , vol.27 , Issue.12 , pp. 3135-3142
    • Jonuleit, H.1    Kuhn, U.2    Muller, G.3    Steinbrink, K.4    Paragnik, L.5    Schmitt, E.6    Knop, J.7    Enk, A.H.8
  • 70
    • 13944260898 scopus 로고    scopus 로고
    • + T cell populations lacking helper function
    • + T cell populations lacking helper function. Nat. Immunol. 6(2), 163-170 (2005).
    • (2005) Nat. Immunol. , vol.6 , Issue.2 , pp. 163-170
    • Sporri, R.1    Reis E Sousa, C.2
  • 72
    • 43249108762 scopus 로고    scopus 로고
    • Comparison of α-type-1 polarizing and standard dendritic cell cytokine cocktail for maturation of therapeutic monocytederived dendritic cell preparations from cancer patients
    • Trepiakas R, Pedersen AE, Met O, Hansen MH, Berntsen A, Svane IM. Comparison of α-type-1 polarizing and standard dendritic cell cytokine cocktail for maturation of therapeutic monocytederived dendritic cell preparations from cancer patients. Vaccine 26(23), 2824-2832 (2008).
    • (2008) Vaccine , vol.26 , Issue.23 , pp. 2824-2832
    • Trepiakas, R.1    Pedersen, A.E.2    Met, O.3    Hansen, M.H.4    Berntsen, A.5    Svane, I.M.6
  • 74
    • 67650826075 scopus 로고    scopus 로고
    • Phase II trial of dendritic cells loaded with antigens from self-renewing, proliferating autologous tumor cells as patient-specific anti-tumor vaccines in patients with metastatic melanoma: Final report
    • Dillman RO, Selvan SR, Schiltz PM et al. Phase II trial of dendritic cells loaded with antigens from self-renewing, proliferating autologous tumor cells as patient-specific anti-tumor vaccines in patients with metastatic melanoma: final report. Cancer Biother. Radiopharm. 24(3), 311-319 (2009).
    • (2009) Cancer Biother. Radiopharm. , vol.24 , Issue.3 , pp. 311-319
    • Dillman, R.O.1    Selvan, S.R.2    Schiltz, P.M.3
  • 75
    • 40749136181 scopus 로고    scopus 로고
    • A Phase I clinical study of vaccination of melanoma patients with dendritic cells loaded with allogeneic apoptotic/necrotic melanoma cells. Analysis of toxicity and immune response to the vaccine and of IL-10 1082 promoter genotype as predictor of disease progression
    • von Euw EM, Barrio MM, Furman D et al. A Phase I clinical study of vaccination of melanoma patients with dendritic cells loaded with allogeneic apoptotic/necrotic melanoma cells. Analysis of toxicity and immune response to the vaccine and of IL-10 1082 promoter genotype as predictor of disease progression. J. Transl. Med. 6, 6 (2008).
    • (2008) J. Transl. Med. , vol.6 , pp. 6
    • Von Euw, E.M.1    Barrio, M.M.2    Furman, D.3
  • 76
    • 42649091526 scopus 로고    scopus 로고
    • Phase I/II study of treatment with matured dendritic cells with or without low dose IL-2 in patients with disseminated melanoma
    • DOI 10.1007/s00262-007-0435-8
    • Hersey P, Halliday GM, Farrelly ML, DeSilva C, Lett M, Menzies SW. Phase I/II study of treatment with matured dendritic cells with or without low dose IL-2 in patients with disseminated melanoma. Cancer Immunol. Immunother. 57(7), 1039-1051 (2008). (Pubitemid 351601491)
    • (2008) Cancer Immunology, Immunotherapy , vol.57 , Issue.7 , pp. 1039-1051
    • Hersey, P.1    Halliday, G.M.2    Farrelly, M.L.3    Desilva, C.4    Lett, M.5    Menzies, S.W.6
  • 77
    • 48549095277 scopus 로고    scopus 로고
    • Phase Ib trial assessing autologous, tumor-pulsed dendritic cells as a vaccine administered with or without IL-2 in patients with metastatic melanoma
    • Redman BG, Chang AE, Whitfield J et al. Phase Ib trial assessing autologous, tumor-pulsed dendritic cells as a vaccine administered with or without IL-2 in patients with metastatic melanoma. J. Immunother. 31(6), 591-598 (2008).
    • (2008) J. Immunother. , vol.31 , Issue.6 , pp. 591-598
    • Redman, B.G.1    Chang, A.E.2    Whitfield, J.3
  • 78
    • 0033062377 scopus 로고    scopus 로고
    • + T cell responses to infectious agents, tumors, transplants, and vaccines
    • + T cell responses to infectious agents, tumors, transplants, and vaccines. Adv. Immunol. 73, 1-77 (1999).
    • (1999) Adv. Immunol. , vol.73 , pp. 1-77
    • Yewdell, J.W.1    Norbury, C.C.2    Bennink, J.R.3
  • 79
    • 0035412401 scopus 로고    scopus 로고
    • Highly efficient gene delivery by mRNA electroporation in human hematopoietic cells: Superiority to lipofection and passive pulsing of mRNA and to electroporation of plasmid cDNA for tumor antigen loading of dendritic cells
    • Van Tendeloo VF, Ponsaerts P, Lardon F et al. Highly efficient gene delivery by mRNA electroporation in human hematopoietic cells: superiority to lipofection and passive pulsing of mRNA and to electroporation of plasmid cDNA for tumor antigen loading of dendritic cells. Blood 98(1), 49-56 (2001).
    • (2001) Blood , vol.98 , Issue.1 , pp. 49-56
    • Van Tendeloo, V.F.1    Ponsaerts, P.2    Lardon, F.3
  • 80
    • 4344560470 scopus 로고    scopus 로고
    • Results of a Phase 1 study utilizing monocyte-derived dendritic cells pulsed with tumor RNA in children and young adults with brain cancer
    • Caruso DA, Orme LM, Neale AM et al. Results of a Phase 1 study utilizing monocyte-derived dendritic cells pulsed with tumor RNA in children and young adults with brain cancer. Neuro Oncol. 6(3), 236-246 (2004).
    • (2004) Neuro Oncol. , vol.6 , Issue.3 , pp. 236-246
    • Caruso, D.A.1    Orme, L.M.2    Neale, A.M.3
  • 82
    • 2942559009 scopus 로고    scopus 로고
    • Cancer immunotherapy with mRNA-transfected dendritic cells
    • DOI 10.1111/j.0105-2896.2004.00139.x
    • Gilboa E, Vieweg J. Cancer immunotherapy with mRNA-transfected dendritic cells. Immunol. Rev. 199, 251-263 (2004). (Pubitemid 38744521)
    • (2004) Immunological Reviews , vol.199 , pp. 251-263
    • Gilboa, E.1    Vieweg, J.2
  • 84
    • 33645222947 scopus 로고    scopus 로고
    • Dendritoma vaccination combined with low dose interleukin-2 in metastatic melanoma patients induced immunological and clinical responses
    • Wei Y, Sticca RP, Holmes LM et al. Dendritoma vaccination combined with low dose interleukin-2 in metastatic melanoma patients induced immunological and clinical responses. Int. J. Oncol. 28(3), 585-593 (2006).
    • (2006) Int. J. Oncol. , vol.28 , Issue.3 , pp. 585-593
    • Wei, Y.1    Sticca, R.P.2    Holmes, L.M.3
  • 85
    • 0033565923 scopus 로고    scopus 로고
    • Biodistribution and vaccine efficiency of murine dendritic cells are dependent on the route of administration
    • Eggert AA, Schreurs MW, Boerman OC et al. Biodistribution and vaccine efficiency of murine dendritic cells are dependent on the route of administration. Cancer Res. 59(14), 3340-3345 (1999).
    • (1999) Cancer Res. , vol.59 , Issue.14 , pp. 3340-3345
    • Eggert, A.A.1    Schreurs, M.W.2    Boerman, O.C.3
  • 86
    • 0032918091 scopus 로고    scopus 로고
    • Migration of human dendritic cells after injection in patients with metastatic malignancies
    • Morse MA, Coleman RE, Akabani G, Niehaus N, Coleman D, Lyerly HK. Migration of human dendritic cells after injection in patients with metastatic malignancies. Cancer Res. 59(1), 56-58 (1999). (Pubitemid 29062955)
    • (1999) Cancer Research , vol.59 , Issue.1 , pp. 56-58
    • Morse, M.A.1    Coleman, R.E.2    Akabani, G.3    Niehaus, N.4    Coleman, D.5    Lyerly, H.K.6
  • 87
    • 0037226599 scopus 로고    scopus 로고
    • Effective migration of antigen-pulsed dendritic cells to lymph nodes in melanoma patients is determined by their maturation state
    • De Vries IJ, Krooshoop DJ, Scharenborg NM et al. Effective migration of antigen-pulsed dendritic cells to lymph nodes in melanoma patients is determined by their maturation state. Cancer Res. 63(1), 12-17 (2003).
    • (2003) Cancer Res. , vol.63 , Issue.1 , pp. 12-17
    • De Vries, I.J.1    Krooshoop, D.J.2    Scharenborg, N.M.3
  • 89
    • 0031570045 scopus 로고    scopus 로고
    • In vivo migration of dendritic cells differentiated in vitro: A chimpanzee model
    • Barratt-Boyes SM, Watkins SC, Finn OJ. In vivo migration of dendritic cells differentiated in vitro: a chimpanzee model. J. Immunol. 158(10), 4543-4547 (1997).
    • (1997) J. Immunol. , vol.158 , Issue.10 , pp. 4543-4547
    • Barratt-Boyes, S.M.1    Watkins, S.C.2    Finn, O.J.3
  • 90
    • 0035869523 scopus 로고    scopus 로고
    • Dendritic cells injected via different routes induce immunity in cancer patients
    • Fong L, Brockstedt D, Benike C, Wu L, Engleman EG. Dendritic cells injected via different routes induce immunity in cancer patients. J. Immunol. 166(6), 4254-4259 (2001). (Pubitemid 32224961)
    • (2001) Journal of Immunology , vol.166 , Issue.6 , pp. 4254-4259
    • Fong, L.1    Brockstedt, D.2    Benike, C.3    Wu, L.4    Engleman, E.G.5
  • 91
    • 0034193987 scopus 로고    scopus 로고
    • T cell activity after dendritic cell vaccination is dependent on both the type of antigen and the mode of delivery
    • Serody JS, Collins EJ, Tisch RM, Kuhns JJ, Frelinger JA. T cell activity after dendritic cell vaccination is dependent on both the type of antigen and the mode of delivery. J. Immunol. 164(9), 4961-4967 (2000).
    • (2000) J. Immunol. , vol.164 , Issue.9 , pp. 4961-4967
    • Serody, J.S.1    Collins, E.J.2    Tisch, R.M.3    Kuhns, J.J.4    Frelinger, J.A.5
  • 93
    • 0036812718 scopus 로고    scopus 로고
    • Antigens derived from melanocyte differentiation proteins: Self-tolerance, autoimmunity, and use for cancer immunotherapy
    • Engelhard VH, Bullock TN, Colella TA, Sheasley SL, Mullins DW. Antigens derived from melanocyte differentiation proteins: self-tolerance, autoimmunity, and use for cancer immunotherapy. Immunol. Rev. 188, 136-146 (2002).
    • (2002) Immunol. Rev. , vol.188 , pp. 136-146
    • Engelhard, V.H.1    Bullock, T.N.2    Colella, T.A.3    Sheasley, S.L.4    Mullins, D.W.5
  • 94
    • 11144232998 scopus 로고    scopus 로고
    • Human high molecular weight-melanoma-associated antigen (HMW-MAA): A melanoma cell surface chondroitin sulfate proteoglycan (MSCP) with biological and clinical significance
    • DOI 10.1615/CritRevImmunol.v24.i4.40
    • Campoli MR, Chang CC, Kageshita T, Wang X, McCarthy JB, Ferrone S. Human high molecular weight-melanoma-associated antigen (HMW-MAA): a melanoma cell surface chondroitin sulfate proteoglycan (MSCP) with biological and clinical significance. Crit. Rev. Immunol. 24(4), 267-296 (2004). (Pubitemid 40052428)
    • (2004) Critical Reviews in Immunology , vol.24 , Issue.4 , pp. 267-296
    • Campoli, M.R.1    Chang, C.-C.2    Kageshita, T.3    Wang, X.4    McCarthy, J.B.5    Ferrone, S.6
  • 95
    • 0032706622 scopus 로고    scopus 로고
    • Analysis of human transcriptomes
    • Velculescu VE, Madden SL, Zhang L et al. Analysis of human transcriptomes. Nat. Genet. 23(4), 387-388 (1999).
    • (1999) Nat. Genet. , vol.23 , Issue.4 , pp. 387-388
    • Velculescu, V.E.1    Madden, S.L.2    Zhang, L.3
  • 96
    • 34347231636 scopus 로고    scopus 로고
    • Melanocyte expression of survivin promotes development and metastasis of UV-induced melanoma in HGF-transgenic mice
    • DOI 10.1158/0008-5472.CAN-06-3669
    • Thomas J, Liu T, Cotter MA et al. Melanocyte expression of survivin promotes development and metastasis of UV-induced melanoma in HGF-transgenic mice. Cancer Res. 67(11), 5172-5178 (2007). (Pubitemid 46997254)
    • (2007) Cancer Research , vol.67 , Issue.11 , pp. 5172-5178
    • Thomas, J.1    Liu, T.2    Cotter, M.A.3    Florell, S.R.4    Robinette, K.5    Hanks, A.N.6    Grossman, D.7
  • 97
    • 0026584248 scopus 로고
    • Human high molecular weight melanoma-associated antigen (HMWMAA) mimicry by mouse anti-idiotypic monoclonal antibody MK2-23: Induction of humoral anti-HMW-MAA immunity and prolongation of survival in patients with stage IV melanoma
    • Mittelman A, Chen ZJ, Yang H, Wong GY, Ferrone S. Human high molecular weight melanoma-associated antigen (HMWMAA) mimicry by mouse anti-idiotypic monoclonal antibody MK2-23: induction of humoral anti-HMW-MAA immunity and prolongation of survival in patients with stage IV melanoma. Proc. Natl Acad. Sci. USA 89(2), 466-470 (1992).
    • (1992) Proc. Natl Acad. Sci. USA , vol.89 , Issue.2 , pp. 466-470
    • Mittelman, A.1    Chen, Z.J.2    Yang, H.3    Wong, G.Y.4    Ferrone, S.5
  • 99
    • 28544453333 scopus 로고    scopus 로고
    • Cell biology: Chromosome alignment and segregation regulated by ubiquitination of survivin
    • DOI 10.1126/science.1120160
    • Vong QP, Cao K, Li HY, Iglesias PA, Zheng Y. Chromosome alignment and segregation regulated by ubiquitination of survivin. Science 310(5753), 1499-1504 (2005). (Pubitemid 41746347)
    • (2005) Science , vol.310 , Issue.5753 , pp. 1499-1504
    • Vong, Q.P.1    Cao, K.2    Li, H.Y.3    Iglesias, P.A.4    Zheng, Y.5
  • 101
    • 33745593715 scopus 로고    scopus 로고
    • Complete remission of liver metastasis of pancreatic cancer under vaccination with a HLA-A2 restricted peptide derived from the universal tumor antigen survivin
    • DOI 10.1007/s00262-005-0102-x
    • Wobser M, Keikavoussi P, Kunzmann V, Weininger M, Andersen MH, Becker JC. Complete remission of liver metastasis of pancreatic cancer under vaccination with a HLA-A2 restricted peptide derived from the universal tumor antigen survivin. Cancer Immunol. Immunother. 55(10), 1294-1298 (2006). (Pubitemid 43992055)
    • (2006) Cancer Immunology, Immunotherapy , vol.55 , Issue.10 , pp. 1294-1298
    • Wobser, M.1    Keikavoussi, P.2    Kunzmann, V.3    Weininger, M.4    Andersen, M.H.5    Becker, J.C.6
  • 103
    • 0036721629 scopus 로고    scopus 로고
    • Prevalence of regulatory T cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinoma
    • Liyanage UK, Moore TT, Joo HG et al. Prevalence of regulatory T cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinoma. J. Immunol. 169(5), 2756-2761 (2002).
    • (2002) J. Immunol. , vol.169 , Issue.5 , pp. 2756-2761
    • Liyanage, U.K.1    Moore, T.T.2    Joo, H.G.3
  • 105
    • 0030724702 scopus 로고    scopus 로고
    • Dendritic cells as mediators of tumor-induced tolerance in metastatic melanoma
    • DOI 10.1002/(SICI)1097-0215(19971104)73:3<309::AID-IJC1>3.0.CO;2-3
    • Enk AH, Jonuleit H, Saloga J, Knop J. Dendritic cells as mediators of tumor-induced tolerance in metastatic melanoma. Int. J. Cancer 73(3), 309-316 (1997). (Pubitemid 27508890)
    • (1997) International Journal of Cancer , vol.73 , Issue.3 , pp. 309-316
    • Enk, A.H.1    Jonuleit, H.2    Saloga, J.3    Knop, J.4
  • 107
    • 0036378101 scopus 로고    scopus 로고
    • Immature, but not inactive: The tolerogenic function of immature dendritic cells
    • Mahnke K, Schmitt E, Bonifaz L, Enk AH, Jonuleit H. Immature, but not inactive: the tolerogenic function of immature dendritic cells. Immunol. Cell. Biol. 80(5), 477-483 (2002).
    • (2002) Immunol. Cell. Biol. , vol.80 , Issue.5 , pp. 477-483
    • Mahnke, K.1    Schmitt, E.2    Bonifaz, L.3    Enk, A.H.4    Jonuleit, H.5
  • 109
    • 34247504608 scopus 로고    scopus 로고
    • + human regulatory T cells in vivo: Kinetics of Treg depletion and alterations in immune functions in vivo and in vitro
    • Enhancing effectiveness of DC-based cancer vaccines by depletion of Tregs.
    • + human regulatory T cells in vivo: kinetics of Treg depletion and alterations in immune functions in vivo and in vitro. Int. J. Cancer 120(12), 2723-2733 (2007). • Enhancing effectiveness of DC-based cancer vaccines by depletion of Tregs.
    • (2007) Int. J. Cancer , vol.120 , Issue.12 , pp. 2723-2733
    • Mahnke, K.1    Schonfeld, K.2    Fondel, S.3
  • 110
    • 27444435581 scopus 로고    scopus 로고
    • 389IL-2, ONTAK) to eliminate regulatory T lymphocytes in patients with melanoma
    • Attia P, Maker AV, Haworth LR, Rogers-Freezer L, Rosenberg SA. Inability of a fusion protein of IL-2 and diphtheria toxin (Denileukin Diftitox, DAB389IL-2, ONTAK) to eliminate regulatory T lymphocytes in patients with melanoma. J. Immunother. 28(6), 582-592 (2005). (Pubitemid 41533092)
    • (2005) Journal of Immunotherapy , vol.28 , Issue.6 , pp. 582-592
    • Attia, P.1    Maker, A.V.2    Haworth, L.R.3    Rogers-Freezer, L.4    Rosenberg, S.A.5
  • 111
    • 33745946911 scopus 로고    scopus 로고
    • Therapeutic potential of Toll-like receptor 9 activation
    • Toll-like receptor 9 agonists as potential agents to be combined with DC-based vaccination
    • Krieg AM. Therapeutic potential of Toll-like receptor 9 activation. Nat. Rev. Drug Discov. 5(6), 471-484 (2006). • Toll-like receptor 9 agonists as potential agents to be combined with DC-based vaccination.
    • (2006) Nat. Rev. Drug Discov. , vol.5 , Issue.6 , pp. 471-484
    • Krieg, A.M.1
  • 113
    • 4143086928 scopus 로고    scopus 로고
    • Enhanced dendritic cell antigen capture via Toll-like receptor-induced actin remodeling
    • West MA, Wallin RP, Matthews SP et al. Enhanced dendritic cell antigen capture via Toll-like receptor-induced actin remodeling. Science 305(5687), 1153-1157 (2004).
    • (2004) Science , vol.305 , Issue.5687 , pp. 1153-1157
    • West, M.A.1    Wallin, R.P.2    Matthews, S.P.3
  • 114
    • 14644390867 scopus 로고    scopus 로고
    • + T cell responses to vaccination with peptide, IFA, and CpG oligodeoxynucleotide 7909
    • + T cell responses to vaccination with peptide, IFA, and CpG oligodeoxynucleotide 7909. J. Clin. Invest. 115(3), 739-746 (2005).
    • (2005) J. Clin. Invest. , vol.115 , Issue.3 , pp. 739-746
    • Speiser, D.E.1    Lienard, D.2    Rufer, N.3
  • 115
    • 0023270567 scopus 로고
    • A new member of the immunoglobulin superfamily - CTLA-4
    • DOI 10.1038/328267a0
    • Brunet JF, Denizot F, Luciani MF et al. A new member of the immunoglobulin superfamily - CTLA-4. Nature 328(6127), 267-270 (1987). (Pubitemid 17108278)
    • (1987) Nature , vol.328 , Issue.6127 , pp. 267-270
    • Brunet, J.-F.1    Denizot, F.2    Luciani, M.-F.3
  • 116
    • 33646794392 scopus 로고    scopus 로고
    • Checkpoint blockade in cancer immunotherapy
    • Anti-CTLA-4-antibodies as potential agents to be combined with DC-based vaccination
    • Korman AJ, Peggs KS, Allison JP. Checkpoint blockade in cancer immunotherapy. Adv. Immunol. 90, 297-339 (2006). • Anti-CTLA-4-antibodies as potential agents to be combined with DC-based vaccination.
    • (2006) Adv. Immunol. , vol.90 , pp. 297-339
    • Korman, A.J.1    Peggs, K.S.2    Allison, J.P.3
  • 117
    • 28844469865 scopus 로고    scopus 로고
    • Clinical trials with tumor antigen genetically modified dendritic cells
    • DOI 10.1053/j.seminoncol.2005.09.002, PII S0093775405003593, Gene Therapy of Cancer
    • Ribas A. Clinical trials with tumor antigen genetically modified dendritic cells. Semin. Oncol. 32(6), 556-562 (2005). (Pubitemid 41772683)
    • (2005) Seminars in Oncology , vol.32 , Issue.6 , pp. 556-562
    • Ribas, A.1
  • 119
    • 0029120245 scopus 로고
    • CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation
    • Krummel MF, Allison JP. CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation. J. Exp. Med. 182(2), 459-465 (1995).
    • (1995) J. Exp. Med. , vol.182 , Issue.2 , pp. 459-465
    • Krummel, M.F.1    Allison, J.P.2
  • 121
    • 34548240159 scopus 로고    scopus 로고
    • Tremelimumab (CP-675,206), a cytotoxic T lymphocyte-associated antigen 4 blocking monoclonal antibody in clinical development for patients with cancer
    • DOI 10.1634/theoncologist.12-7-873
    • Ribas A, Hanson DC, Noe DA et al. Tremelimumab (CP-675,206), a cytotoxic T lymphocyte associated antigen 4 blocking monoclonal antibody in clinical development for patients with cancer. Oncologist 12(7), 873-883 (2007). (Pubitemid 47328230)
    • (2007) Oncologist , vol.12 , Issue.7 , pp. 873-883
    • Ribas, A.1    Hanson, D.C.2    Noe, D.A.3    Millham, R.4    Guyot, D.J.5    Bernstein, S.H.6    Canniff, P.C.7    Sharma, A.8    Gomez-Navarro, J.9
  • 122
    • 53549102755 scopus 로고    scopus 로고
    • The tumor microenvironment and its role in promoting tumor growth
    • Whiteside TL. The tumor microenvironment and its role in promoting tumor growth. Oncogene 27(45), 5904-5912 (2008).
    • (2008) Oncogene , vol.27 , Issue.45 , pp. 5904-5912
    • Whiteside, T.L.1
  • 123
    • 67651076283 scopus 로고    scopus 로고
    • American Cancer Society
    • American Cancer Society, Cancer Facts and Figures 2009 www.cancer.org/downloads/ STT/500809web.pdf
    • (2009) Cancer Facts and Figures
  • 124
    • 71949096938 scopus 로고    scopus 로고
    • Melanoma Fact Sheet
    • American Academy of Dermatology, Melanoma Fact Sheet www.aad.org/media/ background/ factsheets/fact-melanoma.html


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.