Key role of the GITR/GITRLigand pathway in the development of murine autoimmune diabetes: A potential therapeutic target

PLoS ONE

Volumn 4, Issue 11, 2009, Pages

  You, Sylvaine ^a,b   Poulton, Lynn ^c   Cobbold, Steve ^c   Liu, Chih Pin ^d   Rosenzweig, Michael ^e   Ringler, Douglas ^e   Lee, Wen Hui ^d   Segovia, Berta ^a,b   Bach, Jean François ^a,b   Waldmann, Herman ^c   Chatenoud, Lucienne ^a,b  

^a UNIVERSITÉ PARIS DESCARTES   (France)

^b INSERM   (France)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

^e Tolerx Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CYTOKINE RECEPTOR; GLUCOCORTICOID INDUCED TUMOR NECROSIS FACTOR RECEPTOR; GLUCOCORTICOID INDUCED TUMOR NECROSIS FACTOR RECEPTOR LIGAND; INTERLEUKIN 2 RECEPTOR ALPHA; TRANSCRIPTION FACTOR FOXP3; UNCLASSIFIED DRUG; LIGAND; NERVE GROWTH FACTOR RECEPTOR; TNFRSF18 PROTEIN, MOUSE; TNFSF18 PROTEIN, MOUSE; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN PRESENTING CELL; ARTICLE; AUTOIMMUNE DISEASE; CELL ACTIVATION; CELL COUNT; CELL INTERACTION; CELL MIGRATION; CELL PROLIFERATION; CELLULAR IMMUNITY; CONTROLLED STUDY; DIABETES MELLITUS; ENDOTHELIUM CELL; FEMALE; MOUSE; NONHUMAN; PANCREAS ISLET; PHENOTYPE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; REGULATORY T LYMPHOCYTE; SIGNAL TRANSDUCTION; T LYMPHOCYTE; ANIMAL; CD4+ T LYMPHOCYTE; CYTOLOGY; GENETICS; IMMUNOLOGY; INSULIN DEPENDENT DIABETES MELLITUS; LYMPH NODE; METABOLISM; MOUSE MUTANT; NONOBESE DIABETIC MOUSE; PATHOLOGY; PHYSIOLOGY; SPLEEN;

MURINAE; MUS;

ANIMALS; ANTIGEN-PRESENTING CELLS; CD4-POSITIVE T-LYMPHOCYTES; CELL PROLIFERATION; DIABETES MELLITUS, TYPE 1; ENDOTHELIAL CELLS; FEMALE; LIGANDS; LYMPH NODES; MICE; MICE, INBRED NOD; MICE, SCID; RECEPTORS, NERVE GROWTH FACTOR; RECEPTORS, TUMOR NECROSIS FACTOR; SPLEEN; TUMOR NECROSIS FACTORS;

EID: 70949096864     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0007848     Document Type: Article

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