메뉴 건너뛰기




Volumn 163, Issue 3, 1999, Pages 1178-1187

Induction of glutamic acid decarboxylase 65-specific Th2 cells and suppression of autoimmune diabetes at late stages of disease is epitope dependent

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIGEN; EPITOPE; GLUTAMATE DECARBOXYLASE; GLUTAMATE DECARBOXYLASE 65; INTERLEUKIN 4; PEPTIDE; T LYMPHOCYTE ANTIGEN; UNCLASSIFIED DRUG;

EID: 0033178763     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (168)

References (36)
  • 1
    • 0028026652 scopus 로고
    • Insulin-dependent diabetes mellitus as an autoimmune disease
    • Bach, J. F. 1994. Insulin-dependent diabetes mellitus as an autoimmune disease. Endocr. Rev. 15:516.
    • (1994) Endocr. Rev. , vol.15 , pp. 516
    • Bach, J.F.1
  • 2
    • 0025234628 scopus 로고
    • Type-1 diabetes: A chronic autoimmune disease of human, mouse, and rat
    • Castano, L., and G. S. Eisenbarth. 1990. Type-1 diabetes: a chronic autoimmune disease of human, mouse, and rat. Annu. Rev. Immunol. 8:647.
    • (1990) Annu. Rev. Immunol. , vol.8 , pp. 647
    • Castano, L.1    Eisenbarth, G.S.2
  • 3
    • 0029954214 scopus 로고    scopus 로고
    • Insulin dependent diabetes mellitus
    • Tisch, R., and H. O. McDevitt. 1996. Insulin dependent diabetes mellitus. Cell 85:291.
    • (1996) Cell , vol.85 , pp. 291
    • Tisch, R.1    McDevitt, H.O.2
  • 4
    • 0027908753 scopus 로고
    • Immune response to glutamic acid decarboxylase correlates with insulitis in nonobese diabetic mice
    • Tisch, R., X. D. Yang, S. M. Singer, R. S. Liblau, L. Fugger, and H. O. McDevitt. 1993. Immune response to glutamic acid decarboxylase correlates with insulitis in nonobese diabetic mice. Nature 366:72.
    • (1993) Nature , vol.366 , pp. 72
    • Tisch, R.1    Yang, X.D.2    Singer, S.M.3    Liblau, R.S.4    Fugger, L.5    McDevitt, H.O.6
  • 6
    • 0032543998 scopus 로고    scopus 로고
    • Widespread expression of an autoantigen-GAD65 transgene does not tolerize non-obese diabetic mice and can exacerbate disease
    • Geng, L., M. Solimena, R. A. Flavell, R. S. Sherwin, and A. C. Hayday. 1998. Widespread expression of an autoantigen-GAD65 transgene does not tolerize non-obese diabetic mice and can exacerbate disease. Proc. Natl. Acad. Sci. USA 95:10055.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 10055
    • Geng, L.1    Solimena, M.2    Flavell, R.A.3    Sherwin, R.S.4    Hayday, A.C.5
  • 7
    • 0028007192 scopus 로고
    • Cellular immunity to a determinant common to glutamate decarboxylase and coxsackie virus in insulin dependent diabetes
    • Atkinson, M. A., M. A. Bowman, L. Campbell, B. L. Harrow, D. L. Kaufman, and N. K. Maclaren. 1994. Cellular immunity to a determinant common to glutamate decarboxylase and coxsackie virus in insulin dependent diabetes. J. Clin. Invest. 94:2125.
    • (1994) J. Clin. Invest. , vol.94 , pp. 2125
    • Atkinson, M.A.1    Bowman, M.A.2    Campbell, L.3    Harrow, B.L.4    Kaufman, D.L.5    Maclaren, N.K.6
  • 9
    • 0031452948 scopus 로고    scopus 로고
    • Determinant spreading of T helper cell 2 (Th2) responses to pancreatic islet autoantigens
    • Tian, J., P. V. Lehmann, and D. L. Kaufman. 1997. Determinant spreading of T helper cell 2 (Th2) responses to pancreatic islet autoantigens. J. Exp. Med. 186: 2039.
    • (1997) J. Exp. Med. , vol.186 , pp. 2039
    • Tian, J.1    Lehmann, P.V.2    Kaufman, D.L.3
  • 10
    • 0028354067 scopus 로고
    • Immunoregulatory and cytokine imbalances in the pathogenesis of IDDM: Therapeutic intervention by immunostimulation?
    • Rabinovitch, A. 1994. Immunoregulatory and cytokine imbalances in the pathogenesis of IDDM: therapeutic intervention by immunostimulation? Diabetes 43:613.
    • (1994) Diabetes , vol.43 , pp. 613
    • Rabinovitch, A.1
  • 11
    • 0029838995 scopus 로고    scopus 로고
    • Pancreatic expression of interleukin-4 abrogates insulitis and autoimmune diabetes in nonobese diabetic (NOD) mice
    • Mueller, R., T. Krahl, and N. Sarvetnick. 1996. Pancreatic expression of interleukin-4 abrogates insulitis and autoimmune diabetes in nonobese diabetic (NOD) mice. J. Exp. Med. 184:1093.
    • (1996) J. Exp. Med. , vol.184 , pp. 1093
    • Mueller, R.1    Krahl, T.2    Sarvetnick, N.3
  • 12
    • 0032033419 scopus 로고    scopus 로고
    • Cytokines induce the development of functionally heterogenous T helper cell subsets
    • O'Garra, A. 1998. Cytokines induce the development of functionally heterogenous T helper cell subsets. Immunity 8:275.
    • (1998) Immunity , vol.8 , pp. 275
    • O'Garra, A.1
  • 15
    • 0031573072 scopus 로고    scopus 로고
    • IL-4 prevents insulitis and insulin-dependent diabetes mellitus in nonobese diabetic mice by potentiation of regulatory T helper-2 cell function
    • Cameron, M. J., G. A. Arreaza, P. Zucker, S. W. Chensue, R. M. Streiter, S. Chakrabarti, and T. L. Delovitch. 1997. IL-4 prevents insulitis and insulin-dependent diabetes mellitus in nonobese diabetic mice by potentiation of regulatory T helper-2 cell function. J. Immunol. 159:4686.
    • (1997) J. Immunol. , vol.159 , pp. 4686
    • Cameron, M.J.1    Arreaza, G.A.2    Zucker, P.3    Chensue, S.W.4    Streiter, R.M.5    Chakrabarti, S.6    Delovitch, T.L.7
  • 16
    • 0029030964 scopus 로고
    • T helper subsets in insulin dependent diabetes
    • Katz, J. D., C. Benoist, and D. Mathis. 1995. T helper subsets in insulin dependent diabetes. Science 268:1185.
    • (1995) Science , vol.268 , pp. 1185
    • Katz, J.D.1    Benoist, C.2    Mathis, D.3
  • 17
    • 0030742237 scopus 로고    scopus 로고
    • T helper 2 (Th2) T cells induce acute pancreatitis and diabetes in immune-compromised nonobese diabetic (NOD) mice
    • Pakala, S. V., M. O. Kurrer, and J. D. Katz. 1997. T helper 2 (Th2) T cells induce acute pancreatitis and diabetes in immune-compromised nonobese diabetic (NOD) mice. J. Exp. Med. 186:299.
    • (1997) J. Exp. Med. , vol.186 , pp. 299
    • Pakala, S.V.1    Kurrer, M.O.2    Katz, J.D.3
  • 18
    • 0029982537 scopus 로고    scopus 로고
    • Genetic analysis of autoimmune disease
    • Vyse, T., and J. A. Todd. 1996. Genetic analysis of autoimmune disease. Cell 85:311.
    • (1996) Cell , vol.85 , pp. 311
    • Vyse, T.1    Todd, J.A.2
  • 19
    • 0029923430 scopus 로고    scopus 로고
    • Nasal administration of glutamic acid decarboxylase (GAD65) peptides induces Th2 responses and prevents murine insulin-dependent diabetes
    • Tian, J., M. A. Atkinson, M. Clare-Salzler, A. Herschenfeld, T. Forsthuber, P. V. Lehmann, and D. L. Kaufman. 1996. Nasal administration of glutamic acid decarboxylase (GAD65) peptides induces Th2 responses and prevents murine insulin-dependent diabetes. J. Exp. Med. 183:1561.
    • (1996) J. Exp. Med. , vol.183 , pp. 1561
    • Tian, J.1    Atkinson, M.A.2    Clare-Salzler, M.3    Herschenfeld, A.4    Forsthuber, T.5    Lehmann, P.V.6    Kaufman, D.L.7
  • 20
    • 0031831753 scopus 로고    scopus 로고
    • Induction of GAD65-specific regulatory T cells inhibits ongoing autoimmune diabetes in nonobese diabetic mice
    • Tisch, R., R. S. Liblau, X. D. Yang, P. Liblau, and H. O. McDevitt. 1998. Induction of GAD65-specific regulatory T cells inhibits ongoing autoimmune diabetes in nonobese diabetic mice. Diabetes 47:894.
    • (1998) Diabetes , vol.47 , pp. 894
    • Tisch, R.1    Liblau, R.S.2    Yang, X.D.3    Liblau, P.4    McDevitt, H.O.5
  • 23
    • 0028874351 scopus 로고
    • The effect of antigen dose in a T cell receptor α /β-transgenic model
    • Hosken, N. A., K. Shibuya, A. W. Heath, K. M. Murphy, and A. O'Garra. 1995. The effect of antigen dose in a T cell receptor α /β-transgenic model. J. Exp. Med. 182:1579.
    • (1995) J. Exp. Med. , vol.182 , pp. 1579
    • Hosken, N.A.1    Shibuya, K.2    Heath, A.W.3    Murphy, K.M.4    O'Garra, A.5
  • 24
    • 0026328818 scopus 로고
    • Generation and analysis of interleukin-4 deficient mice
    • Kuhn, R., K. Rajewsky, and W. Muller. 1991. Generation and analysis of interleukin-4 deficient mice. Science 254:707.
    • (1991) Science , vol.254 , pp. 707
    • Kuhn, R.1    Rajewsky, K.2    Muller, W.3
  • 28
    • 0029670540 scopus 로고    scopus 로고
    • Induction of Th1 and Th2 immunity in neonatal mice
    • Forsthuber, T., H. C. Yip, and P. V. Lehmann. 1996. Induction of Th1 and Th2 immunity in neonatal mice. Science 271:1728.
    • (1996) Science , vol.271 , pp. 1728
    • Forsthuber, T.1    Yip, H.C.2    Lehmann, P.V.3
  • 29
    • 0031854249 scopus 로고    scopus 로고
    • Interleukin-4 deficiency does not exacerbate disease in NOD mice
    • Wang, B. A. Gonzalez, P. Hoglund, J. D. Katz, C. Benoist, and D. Mathis. 1998. Interleukin-4 deficiency does not exacerbate disease in NOD mice. Diabetes 47: 1207.
    • (1998) Diabetes , vol.47 , pp. 1207
    • Wang1    Gonzalez, B.A.2    Hoglund, P.3    Katz, J.D.4    Benoist, C.5    Mathis, D.6
  • 30
    • 0029796717 scopus 로고    scopus 로고
    • In interleukin-4-deficient mice, alum not only generates T helper 1 responses equivalent to Freund's complete adjuvant, but continues to induce T helper 2 cytokine production
    • Brewer, J. M., M. Conacher, A. Satoskar, H. Bluethmann, and J. Alexander. 1996. In interleukin-4-deficient mice, alum not only generates T helper 1 responses equivalent to Freund's complete adjuvant, but continues to induce T helper 2 cytokine production. Eur. J. Immunol. 26:2062.
    • (1996) Eur. J. Immunol. , vol.26 , pp. 2062
    • Brewer, J.M.1    Conacher, M.2    Satoskar, A.3    Bluethmann, H.4    Alexander, J.5
  • 31
    • 0032543998 scopus 로고    scopus 로고
    • Widespread expression of an autoantigen-GAD65 transgene does not tolerize non-obese diabetic mice and can exacerbate disease
    • Geng, L., M. Solimena, R. A. Flavell, R. S. Sherwin, and A. C. Hayday. 1998. Widespread expression of an autoantigen-GAD65 transgene does not tolerize non-obese diabetic mice and can exacerbate disease. Proc. Natl. Acad. Sci. USA 95:10055.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 10055
    • Geng, L.1    Solimena, M.2    Flavell, R.A.3    Sherwin, R.S.4    Hayday, A.C.5
  • 34
    • 0031891701 scopus 로고    scopus 로고
    • Characterization of novel T cell epitopes on 65 kDa and 67 kDa glutamic acid decarboxylase relevant in autoimmune responses in NOD mice
    • Zechel, M. A., J. F. Elliott, M. A. Atkinson, and B. Singh. 1998. Characterization of novel T cell epitopes on 65 kDa and 67 kDa glutamic acid decarboxylase relevant in autoimmune responses in NOD mice. J. Autoimmun. 11:83.
    • (1998) J. Autoimmun. , vol.11 , pp. 83
    • Zechel, M.A.1    Elliott, J.F.2    Atkinson, M.A.3    Singh, B.4
  • 35
    • 0027407564 scopus 로고
    • In vivo role of interleukin-4 in T cell tolerance induced by aqueous protein antigen
    • Burstein, H. J., and A. K. Abbas. 1993. In vivo role of interleukin-4 in T cell tolerance induced by aqueous protein antigen. J. Exp. Med. 177:457.
    • (1993) J. Exp. Med. , vol.177 , pp. 457
    • Burstein, H.J.1    Abbas, A.K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.