메뉴 건너뛰기




Volumn 21, Issue 1, 2007, Pages 117-129

Genetic and pharmacological inhibition of GITR-GITRL interaction reduces chronic lung injury induced by bleomycin instillation

Author keywords

Fusion protein; Inflammation; Mice; TNFR superfamily

Indexed keywords

BLEOMYCIN; GLUCOCORTICOID INDUCED TUMOR NECROSIS FACTOR RECEPTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; TUMOR NECROSIS FACTOR ALPHA;

EID: 33846022338     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fj.06-6611com     Document Type: Article
Times cited : (39)

References (47)
  • 1
    • 0036936759 scopus 로고    scopus 로고
    • Overview of pulmonary fibrosis
    • Green, F. H. (2002) Overview of pulmonary fibrosis. Chest 122, 334S-339S
    • (2002) Chest , vol.122
    • Green, F.H.1
  • 2
    • 4243944861 scopus 로고    scopus 로고
    • Molecular mechanisms of pulmonary fibrosis
    • Pardo, A., and Selman, M. (2002) Molecular mechanisms of pulmonary fibrosis. Front Biosci. 7, d1743-1761
    • (2002) Front Biosci , vol.7
    • Pardo, A.1    Selman, M.2
  • 3
    • 0023184815 scopus 로고
    • Acute chest pain syndrome during bleomycin infusions
    • White, D. A., Schwartzberg, L. S., Kris, M. G., and Bosl, G. J. (1987) Acute chest pain syndrome during bleomycin infusions. Cancer 59, 1582-1585
    • (1987) Cancer , vol.59 , pp. 1582-1585
    • White, D.A.1    Schwartzberg, L.S.2    Kris, M.G.3    Bosl, G.J.4
  • 4
    • 0020637814 scopus 로고
    • Morphometric estimates of infiltrative cellular changes during the development of bleomycin-induced pulmonary fibrosis in hamsters
    • Chandler, D. B., Hyde, D. M., and Giri, S. N. (1983) Morphometric estimates of infiltrative cellular changes during the development of bleomycin-induced pulmonary fibrosis in hamsters. Am. J. Pathol. 112, 170-177
    • (1983) Am. J. Pathol , vol.112 , pp. 170-177
    • Chandler, D.B.1    Hyde, D.M.2    Giri, S.N.3
  • 5
    • 0025338362 scopus 로고    scopus 로고
    • Lazenby, A. J., Crouch, E. C., McDonald, J. A., and Kuhn, C., 3rd (1990) Remodeling of the lung in bleomycin-induced pulmonary fibrosis in the rat. An immunohistochemical study of laminin, type IV collagen, and fibronectin. Am. Rev. Respir. Dis. 142, 206-214
    • Lazenby, A. J., Crouch, E. C., McDonald, J. A., and Kuhn, C., 3rd (1990) Remodeling of the lung in bleomycin-induced pulmonary fibrosis in the rat. An immunohistochemical study of laminin, type IV collagen, and fibronectin. Am. Rev. Respir. Dis. 142, 206-214
  • 6
    • 0027728298 scopus 로고
    • Variable expression of platelet-derived growth factor family proteins in acute lung injury
    • Walsh, J., Absher, M., and Kelley, J. (1993) Variable expression of platelet-derived growth factor family proteins in acute lung injury. Am. J. Respir. Cell Mol. Biol. 9, 637-644
    • (1993) Am. J. Respir. Cell Mol. Biol , vol.9 , pp. 637-644
    • Walsh, J.1    Absher, M.2    Kelley, J.3
  • 7
    • 0034870839 scopus 로고    scopus 로고
    • Attenuation of bleomycin-induced pulmonary fibrosis by a catalytic antioxidant metalloporphyrin
    • Oury, T. D., Thakker, K., Menache, M., Chang, L. Y., Crapo, J. D., and Day, B. J. (2001) Attenuation of bleomycin-induced pulmonary fibrosis by a catalytic antioxidant metalloporphyrin. Am. J. Respir. Cell Mol. Biol. 25, 164-169
    • (2001) Am. J. Respir. Cell Mol. Biol , vol.25 , pp. 164-169
    • Oury, T.D.1    Thakker, K.2    Menache, M.3    Chang, L.Y.4    Crapo, J.D.5    Day, B.J.6
  • 10
    • 0036170938 scopus 로고    scopus 로고
    • Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-tolerance
    • Shimizu, J., Yamazaki, S., Takahashi, T., Ishida, Y., and Sakaguchi, S. (2002) Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-tolerance. Nat. Immunol. 3, 135-142
    • (2002) Nat. Immunol , vol.3 , pp. 135-142
    • Shimizu, J.1    Yamazaki, S.2    Takahashi, T.3    Ishida, Y.4    Sakaguchi, S.5
  • 11
    • 0036195161 scopus 로고    scopus 로고
    • CD4(+)CD25(+) immunoregulatory T cells: Gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor
    • McHugh, R. S., Whitters, M. J., Piccirillo, C. A., Young, D. A., Shevach, E. M., Collins, M., and Byrne, M. C. (2002) CD4(+)CD25(+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor. Immunity 16, 311-323
    • (2002) Immunity , vol.16 , pp. 311-323
    • McHugh, R.S.1    Whitters, M.J.2    Piccirillo, C.A.3    Young, D.A.4    Shevach, E.M.5    Collins, M.6    Byrne, M.C.7
  • 12
    • 17444414236 scopus 로고    scopus 로고
    • GITR: A multifaceted regulator of immunity belonging to the tumor necrosis factor receptor superfamily
    • Nocentini, G., and Riccardi, C. (2005) GITR: a multifaceted regulator of immunity belonging to the tumor necrosis factor receptor superfamily. Eur. J. Immunol. 35, 1016-1022
    • (2005) Eur. J. Immunol , vol.35 , pp. 1016-1022
    • Nocentini, G.1    Riccardi, C.2
  • 14
    • 0036660176 scopus 로고    scopus 로고
    • Role of GITR in activation response of T lymphocytes
    • Ronchetti, S., Nocentini, G., Riccardi, C., and Pandolfi, P. P. (2002) Role of GITR in activation response of T lymphocytes. Blood 100, 350-352
    • (2002) Blood , vol.100 , pp. 350-352
    • Ronchetti, S.1    Nocentini, G.2    Riccardi, C.3    Pandolfi, P.P.4
  • 15
    • 0037070569 scopus 로고    scopus 로고
    • Recombinant glucocorticoid induced tumor necrosis factor receptor (rGITR) induces NOS in murine macrophage
    • Shin, H. H., Lee, M. H., Kim, S. G., Lee, Y. H., Kwon, B. S., and Choi, H. S. (2002) Recombinant glucocorticoid induced tumor necrosis factor receptor (rGITR) induces NOS in murine macrophage. FEBS Lett. 514, 275-280
    • (2002) FEBS Lett , vol.514 , pp. 275-280
    • Shin, H.H.1    Lee, M.H.2    Kim, S.G.3    Lee, Y.H.4    Kwon, B.S.5    Choi, H.S.6
  • 17
    • 0033602151 scopus 로고    scopus 로고
    • Identification of a new member of the tumor necrosis factor family and its receptor, a human ortholog of mouse GITR
    • Gurney, A. L., et al. (1999) Identification of a new member of the tumor necrosis factor family and its receptor, a human ortholog of mouse GITR. Curr. Biol. 9, 215-218
    • (1999) Curr. Biol , vol.9 , pp. 215-218
    • Gurney, A.L.1
  • 18
    • 0033525904 scopus 로고    scopus 로고
    • Identification of a novel activation-inducible protein of the tumor necrosis factor receptor superfamily and its ligand
    • Kwon, B., Yu, K. Y., Ni, J., Yu, G. L., Jang, I. K., Kim, Y. J., Xing, L., Liu, D., Wang, S. X., and Kwon, B. S. (1999) Identification of a novel activation-inducible protein of the tumor necrosis factor receptor superfamily and its ligand. J. Biol. Chem. 274, 6056-6061
    • (1999) J. Biol. Chem , vol.274 , pp. 6056-6061
    • Kwon, B.1    Yu, K.Y.2    Ni, J.3    Yu, G.L.4    Jang, I.K.5    Kim, Y.J.6    Xing, L.7    Liu, D.8    Wang, S.X.9    Kwon, B.S.10
  • 19
    • 0141570624 scopus 로고    scopus 로고
    • Identification of a ligand for glucocorticoid-induced tumor necrosis factor receptor constitutively expressed in dendritic cells
    • Yu, K. Y., Kim, H. S., Song, S. Y., Min, S. S., Jeong, J. J., and Youn, B. S. (2003) Identification of a ligand for glucocorticoid-induced tumor necrosis factor receptor constitutively expressed in dendritic cells. Biochem. Biophys. Res. Commun. 310, 433- 438
    • (2003) Biochem. Biophys. Res. Commun , vol.310 , pp. 433-438
    • Yu, K.Y.1    Kim, H.S.2    Song, S.Y.3    Min, S.S.4    Jeong, J.J.5    Youn, B.S.6
  • 20
    • 0037376954 scopus 로고    scopus 로고
    • Soluble glucocorticoid-induced tumor necrosis factor receptor (sGITR) increased MMP-9 activity in murine macrophage
    • Lee, H. S., Shin, H. H., Kwon, B. S., and Choi, H. S. (2003) Soluble glucocorticoid-induced tumor necrosis factor receptor (sGITR) increased MMP-9 activity in murine macrophage. J. Cell. Biochem. 88, 1048-1056
    • (2003) J. Cell. Biochem , vol.88 , pp. 1048-1056
    • Lee, H.S.1    Shin, H.H.2    Kwon, B.S.3    Choi, H.S.4
  • 21
    • 18144395471 scopus 로고    scopus 로고
    • Soluble glucocorticoid-induced tumor necrosis factor receptor (sGITR) stimulates osteoclast differentiation in response to receptor activator of NF-kappaB ligand (RANKL) in osteoclast cells
    • Shin, H. H., Kim, S. J., Lee, D. S., and Choi, H. S. (2005) Soluble glucocorticoid-induced tumor necrosis factor receptor (sGITR) stimulates osteoclast differentiation in response to receptor activator of NF-kappaB ligand (RANKL) in osteoclast cells. Bone 36, 832-839
    • (2005) Bone , vol.36 , pp. 832-839
    • Shin, H.H.1    Kim, S.J.2    Lee, D.S.3    Choi, H.S.4
  • 22
    • 27744561701 scopus 로고    scopus 로고
    • The glucocorticoid-induced tumor necrosis factor receptor-related gene modulates the response to Candida albicans infection
    • Agostini, M., Cenci, E., Pericolini, E., Nocentini, G., Bistoni, G., Vecchiarelli, A., and Riccardi, C. (2005) The glucocorticoid-induced tumor necrosis factor receptor-related gene modulates the response to Candida albicans infection. Infect. Immun. 73, 7502-7508
    • (2005) Infect. Immun , vol.73 , pp. 7502-7508
    • Agostini, M.1    Cenci, E.2    Pericolini, E.3    Nocentini, G.4    Bistoni, G.5    Vecchiarelli, A.6    Riccardi, C.7
  • 24
    • 24644515759 scopus 로고    scopus 로고
    • In vivo kinetics of GITR and GITR ligand expression and their functional significance in regulating viral immunopathology
    • Suvas, S., Kim, B., Sarangi, P. P., Tone, M., Waldmann, H., and Rouse, B. T. (2005) In vivo kinetics of GITR and GITR ligand expression and their functional significance in regulating viral immunopathology. J. Virol. 79, 11935-11942
    • (2005) J. Virol , vol.79 , pp. 11935-11942
    • Suvas, S.1    Kim, B.2    Sarangi, P.P.3    Tone, M.4    Waldmann, H.5    Rouse, B.T.6
  • 25
    • 25844517914 scopus 로고    scopus 로고
    • Treatment of advanced tumors with agonistic anti-GITR mAb and its effects on tumor-infiltrating Foxp3+CD25+CD4+ regulatory T cells
    • Ko, K., Yamazaki, S., Nakamura, K., Nishioka, T., Hirota, K., Yamaguchi, T., Shimizu, J., Nomura, T., Chiba, T., and Sakaguchi, S. (2005) Treatment of advanced tumors with agonistic anti-GITR mAb and its effects on tumor-infiltrating Foxp3+CD25+CD4+ regulatory T cells. J. Exp. Med. 202, 885-891
    • (2005) J. Exp. Med , vol.202 , pp. 885-891
    • Ko, K.1    Yamazaki, S.2    Nakamura, K.3    Nishioka, T.4    Hirota, K.5    Yamaguchi, T.6    Shimizu, J.7    Nomura, T.8    Chiba, T.9    Sakaguchi, S.10
  • 27
    • 7644238339 scopus 로고    scopus 로고
    • Glucocorticoid-induced TNF receptor family gene (GITR) knockout mice exhibit a resistance to splanchnic artery occlusion (SAO) shock
    • Cuzzocrea, S., Nocentini, G., Di Paola, R., Mazzon, E., Ronchetti, S., Genovese, T., Muia, C., Caputi, A. P., and Riccardi, C. (2004) Glucocorticoid-induced TNF receptor family gene (GITR) knockout mice exhibit a resistance to splanchnic artery occlusion (SAO) shock. J. Leukoc. Biol. 76, 933-940
    • (2004) J. Leukoc. Biol , vol.76 , pp. 933-940
    • Cuzzocrea, S.1    Nocentini, G.2    Di Paola, R.3    Mazzon, E.4    Ronchetti, S.5    Genovese, T.6    Muia, C.7    Caputi, A.P.8    Riccardi, C.9
  • 28
    • 0023914820 scopus 로고
    • Simple method of estimating severity of pulmonary fibrosis on a numerical scale
    • Ashcroft, T., Simpson, J. M., and Timbrell, V. (1988) Simple method of estimating severity of pulmonary fibrosis on a numerical scale. J. Clin. Pathol. 41, 467-470
    • (1988) J. Clin. Pathol , vol.41 , pp. 467-470
    • Ashcroft, T.1    Simpson, J.M.2    Timbrell, V.3
  • 29
    • 26244452991 scopus 로고    scopus 로고
    • Green tea polyphenol extract attenuates lung injury in experimental model of carrageenan-induced pleurisy in mice
    • Di Paola, R., Mazzon, E., Muia, C., Genovese, T., Menegazzi, M., Zaffini, R., Suzuki, H., and Cuzzocrea, S. (2005) Green tea polyphenol extract attenuates lung injury in experimental model of carrageenan-induced pleurisy in mice. Respir. Res. 6, 66
    • (2005) Respir. Res , vol.6 , pp. 66
    • Di Paola, R.1    Mazzon, E.2    Muia, C.3    Genovese, T.4    Menegazzi, M.5    Zaffini, R.6    Suzuki, H.7    Cuzzocrea, S.8
  • 30
    • 0021998590 scopus 로고
    • Myeloperoxidase activity as a quantitative assessment of neutrophil infiltration into ischemic myocardium
    • Mullane, K. M., Kraemer, R., and Smith, B. (1985) Myeloperoxidase activity as a quantitative assessment of neutrophil infiltration into ischemic myocardium. J. Pharmacol. Methods 14, 157-167
    • (1985) J. Pharmacol. Methods , vol.14 , pp. 157-167
    • Mullane, K.M.1    Kraemer, R.2    Smith, B.3
  • 31
    • 11844269840 scopus 로고    scopus 로고
    • Phosphorylation of NF-kappaB and IkappaB proteins: Implications in cancer and inflammation
    • Viatour, P., Merville, M. P., Bours, V., and Chariot, A. (2005) Phosphorylation of NF-kappaB and IkappaB proteins: implications in cancer and inflammation. Trends Biochem. Sci. 30, 43-52
    • (2005) Trends Biochem. Sci , vol.30 , pp. 43-52
    • Viatour, P.1    Merville, M.P.2    Bours, V.3    Chariot, A.4
  • 32
    • 32844461448 scopus 로고    scopus 로고
    • Signaling triggered by glucocorticoid-induced tumor necrosis factor receptor family-related gene: Regulation at the interface between regulatory T cells and immune effector cells
    • Esparza, E. M., and Arch, R. H. (2006) Signaling triggered by glucocorticoid-induced tumor necrosis factor receptor family-related gene: regulation at the interface between regulatory T cells and immune effector cells. Front Biosci. 11, 1448-1465
    • (2006) Front Biosci , vol.11 , pp. 1448-1465
    • Esparza, E.M.1    Arch, R.H.2
  • 33
    • 0035793684 scopus 로고    scopus 로고
    • NF-kappaB activation and IkappaB alpha dynamism involved in iNOS and chemokine induction in astroglial cells
    • Nomura, Y. (2001) NF-kappaB activation and IkappaB alpha dynamism involved in iNOS and chemokine induction in astroglial cells. Life Sci. 68, 1695-1701
    • (2001) Life Sci , vol.68 , pp. 1695-1701
    • Nomura, Y.1
  • 34
    • 11144238299 scopus 로고    scopus 로고
    • Control of cyclooxygenase-2 transcriptional activation by pro-inflammatory mediators
    • Wu, K. K. (2005) Control of cyclooxygenase-2 transcriptional activation by pro-inflammatory mediators. Prostaglandins Leukot. Essent. Fatty Acids. 72, 89-93
    • (2005) Prostaglandins Leukot. Essent. Fatty Acids , vol.72 , pp. 89-93
    • Wu, K.K.1
  • 35
    • 0031965748 scopus 로고    scopus 로고
    • Idiopathic pulmonary fibrosis: Clinical relevance of pathologic classification
    • Katzenstein, A. L., and Myers, J. L. (1998) Idiopathic pulmonary fibrosis: clinical relevance of pathologic classification. Am. J. Respir. Crit. Care Med. 157, 1301-1315
    • (1998) Am. J. Respir. Crit. Care Med , vol.157 , pp. 1301-1315
    • Katzenstein, A.L.1    Myers, J.L.2
  • 36
    • 0034011982 scopus 로고    scopus 로고
    • Idiopathic pulmonary fibrosis: Diagnosis and treatment. International consensus statement. American Thoracic Society (ATS), and the European Respiratory Society (ERS)
    • American Thoracic Society
    • American Thoracic Society. (2000) Idiopathic pulmonary fibrosis: diagnosis and treatment. International consensus statement. American Thoracic Society (ATS), and the European Respiratory Society (ERS). Am. J. Respir. Crit. Care Med. 161, 646-664
    • (2000) Am. J. Respir. Crit. Care Med , vol.161 , pp. 646-664
  • 37
    • 0029995678 scopus 로고    scopus 로고
    • Corticosteroids and the treatment of idiopathic pulmonary fibrosis. Past, present, and future
    • Mapel, D. W., Samet, J. M., and Coultas, D. B. (1996) Corticosteroids and the treatment of idiopathic pulmonary fibrosis. Past, present, and future. Chest 110, 1058-1067
    • (1996) Chest , vol.110 , pp. 1058-1067
    • Mapel, D.W.1    Samet, J.M.2    Coultas, D.B.3
  • 39
    • 0026389762 scopus 로고
    • Azathioprine combined with prednisone in the treatment of idiopathic pulmonary fibrosis: A prospective double-blind, randomized, placebo-controlled clinical trial
    • Raghu, G., Depaso, W. J., Cain, K., Hammar, S. P., Wetzel, C. E., Dreis, D. F., Hutchinson, J., Pardee, N. E., and Winterbauer, R. H. (1991) Azathioprine combined with prednisone in the treatment of idiopathic pulmonary fibrosis: a prospective double-blind, randomized, placebo-controlled clinical trial. Am. Rev. Respir. Dis. 144, 291-296
    • (1991) Am. Rev. Respir. Dis , vol.144 , pp. 291-296
    • Raghu, G.1    Depaso, W.J.2    Cain, K.3    Hammar, S.P.4    Wetzel, C.E.5    Dreis, D.F.6    Hutchinson, J.7    Pardee, N.E.8    Winterbauer, R.H.9
  • 40
    • 0024547095 scopus 로고
    • Randomised controlled trial comparing prednisolone alone with cyclophosphamide and low dose prednisolone in combination in cryptogenic fibrosing alveolitis
    • Johnson, M. A., Kwan, S., Snell, N. J., Nunn, A. J., Darbyshire, J. H., and Turner-Warwick, M. (1989) Randomised controlled trial comparing prednisolone alone with cyclophosphamide and low dose prednisolone in combination in cryptogenic fibrosing alveolitis. Thorax 44, 280-288
    • (1989) Thorax , vol.44 , pp. 280-288
    • Johnson, M.A.1    Kwan, S.2    Snell, N.J.3    Nunn, A.J.4    Darbyshire, J.H.5    Turner-Warwick, M.6
  • 42
    • 1842506282 scopus 로고    scopus 로고
    • Leukocyte and endothelial adhesion molecule studies in knockout mice
    • Kakkar, A. K., and Lefer, D. J. (2004) Leukocyte and endothelial adhesion molecule studies in knockout mice. Curr. Opin. Pharmacol. 4, 154-158
    • (2004) Curr. Opin. Pharmacol , vol.4 , pp. 154-158
    • Kakkar, A.K.1    Lefer, D.J.2
  • 43
    • 12444262174 scopus 로고    scopus 로고
    • Rolling of Th1 cells via P-selectin glycoprotein ligand-1 stimulates LFA-1-mediated cell binding to ICAM-1
    • Atarashi, K., Hirata, T., Matsumoto, M., Kanemitsu, N., and Miyasaka, M. (2005) Rolling of Th1 cells via P-selectin glycoprotein ligand-1 stimulates LFA-1-mediated cell binding to ICAM-1. J. Immunol. 174, 1424-1432
    • (2005) J. Immunol , vol.174 , pp. 1424-1432
    • Atarashi, K.1    Hirata, T.2    Matsumoto, M.3    Kanemitsu, N.4    Miyasaka, M.5
  • 44
    • 7044262742 scopus 로고    scopus 로고
    • Nuclear factor (NF)-kappaB proteins: Therapeutic targets
    • ii57-ii61
    • Verma, I. M. (2004) Nuclear factor (NF)-kappaB proteins: therapeutic targets. Ann. Rheum. Dis. 63 Suppl 2, ii57-ii61
    • (2004) Ann. Rheum. Dis , vol.63 , Issue.SUPPL. 2
    • Verma, I.M.1
  • 45
    • 0029952585 scopus 로고    scopus 로고
    • Co-expression of TNF alpha and IL-1 beta in human acute pulmonary fibrotic diseases: An immunohistochemical analysis
    • Pan, L. H., Ohtani, H., Yamauchi, K., and Nagura, H. (1996) Co-expression of TNF alpha and IL-1 beta in human acute pulmonary fibrotic diseases: an immunohistochemical analysis. Pathol. Int. 46, 91-99
    • (1996) Pathol. Int , vol.46 , pp. 91-99
    • Pan, L.H.1    Ohtani, H.2    Yamauchi, K.3    Nagura, H.4
  • 46
    • 0029155678 scopus 로고
    • Potential therapeutic initiatives for fibrogenic lung diseases
    • Goldstein, R. H., and Fine, A. (1995) Potential therapeutic initiatives for fibrogenic lung diseases. Chest 108, 848-855
    • (1995) Chest , vol.108 , pp. 848-855
    • Goldstein, R.H.1    Fine, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.