메뉴 건너뛰기




Volumn 2, Issue 1, 2009, Pages 9-25

Non-linear optical imaging of obesity-related health risks: Review

Author keywords

Atherosclerosis; coherent anti Stokes Raman scattering; lipid droplet; mammary cancer; non linear optics; obesity; second harmonic generation; sum frequency generation; tumor stroma; two photon fluorescence

Indexed keywords

ATHEROSCLEROSIS; COHERENT ANTI-STOKES RAMAN SCATTERING; LIPID DROPLET; MAMMARY CANCER; OBESITY; SUM-FREQUENCY GENERATION; TUMOR STROMA; TWO PHOTON FLUORESCENCE;

EID: 70749132943     PISSN: 17935458     EISSN: 17937205     Source Type: Journal    
DOI: 10.1142/S1793545809000371     Document Type: Review
Times cited : (6)

References (106)
  • 1
    • 3543072186 scopus 로고    scopus 로고
    • Overweight, obesity and cancer: Epidemiological evidence and proposed mechanisms
    • Calle, E. E. and Kaaks, R., "Overweight, obesity and cancer: Epidemiological evidence and proposed mechanisms," Nat. Rev. Cancer 4(8), 579-591 (2004). (Pubitemid 39025053)
    • (2004) Nature Reviews Cancer , vol.4 , Issue.8 , pp. 579-591
    • Calle, E.E.1    Kaaks, R.2
  • 2
    • 0034611791 scopus 로고    scopus 로고
    • Obesity as a medical problem
    • Kopelman, P. G., "Obesity as a medical problem," Nature 404, 635-643 (2000). (Pubitemid 30205068)
    • (2000) Nature , vol.404 , Issue.6778 , pp. 635-643
    • Kopelman, P.G.1
  • 3
    • 0037177592 scopus 로고    scopus 로고
    • Unraveling the causes of diabetes
    • DOI 10.1126/science.296.5568.686
    • Marx, J., "Unraveling the causes of diabetes," Science 296, 686-689 (2002). (Pubitemid 34441985)
    • (2002) Science , vol.296 , Issue.5568 , pp. 686-689
    • Marx, J.1
  • 4
    • 33845864967 scopus 로고    scopus 로고
    • Adipocytes as regulators of energy balance and glucose homeostasis
    • DOI 10.1038/nature05483, PII NATURE05483
    • Rosen, E. D. and Spiegelman, B. M., "Adipocytes as regulators of energy balance and glucose homeostasis," Nature 444, 847-853 (2006). (Pubitemid 46024991)
    • (2006) Nature , vol.444 , Issue.7121 , pp. 847-853
    • Rosen, E.D.1    Spiegelman, B.M.2
  • 5
    • 0033789518 scopus 로고    scopus 로고
    • Adipose tissue as an endocrine organ
    • Ahima, R. S. and Flier, J. S., "Adipose tissue as an endocrine organ," Trends Endocrinol. Metab. 11, 327-332 (2000).
    • (2000) Trends Endocrinol. Metab. , vol.11 , pp. 327-332
    • Ahima, R.S.1    Flier, J.S.2
  • 6
    • 33845886915 scopus 로고    scopus 로고
    • Abdominal obesity and metabolic syndrome
    • DOI 10.1038/nature05488, PII NATURE05488
    • Despres, J. P. and Lemieux, I., "Abdominal obesity and metabolic syndrome," Nature 444, 881-887 (2006). (Pubitemid 46024995)
    • (2006) Nature , vol.444 , Issue.7121 , pp. 881-887
    • Despres, J.-P.1    Lemieux, I.2
  • 7
    • 56249136680 scopus 로고    scopus 로고
    • Coherent anti-Stokes Raman scattering microscopy: Chemically selective imaging for biology and medicine
    • Evans, C. L. and Xie, X. S., "Coherent anti-Stokes Raman scattering microscopy: Chemically selective imaging for biology and medicine," Annu. Rev. Anal. Chem. 1, 883-909 (2008).
    • (2008) Annu. Rev. Anal. Chem. , vol.1 , pp. 883-909
    • Evans, C.L.1    Xie, X.S.2
  • 9
    • 0034330533 scopus 로고    scopus 로고
    • Environmental health and genomics: Visions and implications
    • Olden, K. and Wilson, S., "Environmental health and genomics: Visions and implications," Nat. Rev. Genet. 1, 149-153 (2000).
    • (2000) Nat. Rev. Genet. , vol.1 , pp. 149-153
    • Olden, K.1    Wilson, S.2
  • 10
    • 0032952265 scopus 로고    scopus 로고
    • Role of genetic factors in childhood obesity and in susceptibility to dietary variations
    • Perusse, L. and Bouchard, C., "Role of genetic factors in childhood obesity and in susceptibility to dietary variations," Ann. Med. 31, 19-25 (1999). (Pubitemid 29209700)
    • (1999) Annals of Medicine , vol.31 , Issue.SUPPL. 1 , pp. 19-25
    • Perusse, L.1    Bouchard, C.2
  • 12
    • 0742269402 scopus 로고    scopus 로고
    • Coherent anti-Stokes Raman scattering microscopy: Instrumentation, theory, and applications
    • Cheng, J. X. and Xie, X. S., "Coherent anti-Stokes Raman scattering microscopy: Instrumentation, theory, and applications," J. Phys. Chem. B 108, 827-840 (2004).
    • (2004) J. Phys. Chem. B , vol.108 , pp. 827-840
    • Cheng, J.X.1    Xie, X.S.2
  • 13
    • 34548830831 scopus 로고    scopus 로고
    • Coherent anti-Stokes Raman Scattering microscopy
    • Cheng, J. X., "Coherent anti-Stokes Raman Scattering microscopy," Appl. Spectrosc. 61, 197-208 (2007).
    • (2007) Appl. Spectrosc. , vol.61 , pp. 197-208
    • Cheng, J.X.1
  • 14
    • 30944450665 scopus 로고    scopus 로고
    • Deep tissue twophoton microscopy
    • Helmchen, F. and Denk, W., "Deep tissue twophoton microscopy," Nat. Methods. 2, 932-940 (2005).
    • (2005) Nat. Methods. , vol.2 , pp. 932-940
    • Helmchen, F.1    Denk, W.2
  • 17
    • 33646479329 scopus 로고    scopus 로고
    • Components of metabolic syndrome and coronary artery disease in female Ossabaw swine fed excess atherogenic diet
    • Dyson, M. C., Alloosh, M., Vuchetich, J. P., Mokelke E. A. and Sturek M., "Components of metabolic syndrome and coronary artery disease in female Ossabaw swine fed excess atherogenic diet," Comp. Med. 56, 35-45 (2006).
    • (2006) Comp. Med. , vol.56 , pp. 35-45
    • Dyson, M.C.1    Alloosh, M.2    Vuchetich, J.P.3    Mokelke, E.A.4    Sturek, M.5
  • 18
    • 33845325476 scopus 로고    scopus 로고
    • Adipocyte differentiation from the inside out
    • DOI 10.1038/nrm2066, PII NRM2066
    • Rosen, E. D. and MacDougald, O. A., "Adipocyte differentiation from the inside out," Nat. Rev. Mol. Cell. Biol. 7, 885-896 (2006). (Pubitemid 44871415)
    • (2006) Nature Reviews Molecular Cell Biology , vol.7 , Issue.12 , pp. 885-896
    • Rosen, E.D.1    MacDougald, O.A.2
  • 19
    • 0016243979 scopus 로고
    • Sublines of mouse 3T3 cells that accumulate lipid
    • Green, H. and Kehinde, O., "Sublines of mouse 3T3 cells that accumulate lipid," Cell 1, 113-116 (1974).
    • (1974) Cell , vol.1 , pp. 113-116
    • Green, H.1    Kehinde, O.2
  • 20
    • 2542444253 scopus 로고    scopus 로고
    • Simple flow cytometric method used to assess lipid accumulation in fat cells
    • DOI 10.1194/jlr.D300028-JLR200
    • Lee, Y. H., Chen, S. Y., Wiesner, R. J. and Huang, Y. F., "Simple flow cytometric method used to assess lipid accumulation in fat cells," J. Lipid. Res. 45, 1162-1167 (2004). (Pubitemid 38679513)
    • (2004) Journal of Lipid Research , vol.45 , Issue.6 , pp. 1162-1167
    • Lee, Y.-H.1    Chen, S.-Y.2    Wiesner, R.J.3    Huang, Y.-F.4
  • 21
    • 0344667488 scopus 로고    scopus 로고
    • Vibrational imaging of lipid droplets in live fibroblast cells with coherent anti-Stokes Raman scattering microscopy
    • DOI 10.1194/jlr.D300022-JLR200
    • Nan, X. L., Cheng, J. X. and Xie, X. S., "Vibrational imaging of lipid droplets in live fibroblast cells with coherent anti-Stokes Raman scattering microscopy," J. Lipid. Res. 44, 2202-2208 (2003). (Pubitemid 37509636)
    • (2003) Journal of Lipid Research , vol.44 , Issue.11 , pp. 2202-2208
    • Nan, X.1    Cheng, J.-X.2    Xie, X.S.3
  • 22
    • 33745714382 scopus 로고    scopus 로고
    • Nonperturbative chemical imaging of organelle transport in living cells with coherent anti-stokes Raman scattering microscopy
    • Nan, X. L., Potma, E. O. and Xie, X. S., "Nonperturbative chemical imaging of organelle transport in living cells with coherent anti-stokes Raman scattering microscopy," Biophys. J. 91, 728-735 (2006).
    • (2006) Biophys. J. , vol.91 , pp. 728-735
    • Nan, X.L.1    Potma, E.O.2    Xie, X.S.3
  • 23
    • 34248189053 scopus 로고    scopus 로고
    • CGI-58 facilitates lipolysis on lipid droplets but is not involved in the vesiculation of lipid droplets caused by hormonal stimulation
    • DOI 10.1194/jlr.M600493-JLR200
    • Yamaguchi, T., Omatsu, N., Morimoto, E., Nakashima, H., Ueno, K., Tanaka, T., Satouchi, K., Hirose, F. and Osumi, T., "CGI-58 facilitates lipolysis on lipid droplets but is not involved in the vesiculation of lipid droplets caused by hormonal stimulation," J. Lipid. Res. 48, 1078-1089 (2007). (Pubitemid 46708675)
    • (2007) Journal of Lipid Research , vol.48 , Issue.5 , pp. 1078-1089
    • Yamaguchi, T.1    Omatsu, N.2    Morimoto, E.3    Nakashima, H.4    Ueno, K.5    Tanaka, T.6    Satouchi, K.7    Hirose, F.8    Osumi, T.9
  • 26
    • 0037194959 scopus 로고    scopus 로고
    • Multiplex coherent anti-stokes Raman scattering microspectroscopy and study of lipid vesicles
    • DOI 10.1021/jp025771z
    • Cheng, J. X., Volkmer, A., Book, L. D. and Xie, X. S., "Multiplex coherent anti-Stokes Raman scattering microspectroscopy and study of lipid vesicles," J. Phys. Chem. B 106, 8493-8498 (2002). (Pubitemid 35382856)
    • (2002) Journal of Physical Chemistry B , vol.106 , Issue.34 , pp. 8493-8498
    • Cheng, J.-X.1    Volkmer, A.2    Book, L.D.3    Xie, X.S.4
  • 27
    • 0037062001 scopus 로고    scopus 로고
    • Imaging the thermodynamic state of lipid membranes with multiplex CARS microscopy
    • DOI 10.1021/jp014012y
    • Muller, M. and Schins, J. M., "Imaging the thermodynamic state of lipid membranes with multiplex CARS microscopy," J. Phys. Chem. B 106, 3715-3723 (2002). (Pubitemid 35290225)
    • (2002) Journal of Physical Chemistry B , vol.106 , Issue.14 , pp. 3715-3723
    • Muller, M.1    Schins, J.M.2
  • 28
    • 27744542548 scopus 로고    scopus 로고
    • Quantitative coherent anti-Stokes Raman scattering imaging of lipid distribution in coexisting domains
    • DOI 10.1529/biophysj.105.065607
    • Li, L., Wang,H. F. andCheng, J. X., "Quantitative coherent anti-Stokes Raman scattering imaging of lipid distribution in coexisting domains," Biophys. J. 89, 3480-3490 (2005). (Pubitemid 41636102)
    • (2005) Biophysical Journal , vol.89 , Issue.5 , pp. 3480-3490
    • Li, L.1    Wang, H.2    Cheng, J.-X.3
  • 29
    • 33846131537 scopus 로고    scopus 로고
    • Dual-pump coherent anti-Stokes-Raman scattering microscopy
    • DOI 10.1364/OL.31.003656
    • Burkacky, O., Zumbusch, A., Brackmann, C. and Enejder, A., "Dual-pump coherent anti-Stokes-Raman scattering microscopy," Opt. Lett. 31, 3656-3658 (2006). (Pubitemid 46079733)
    • (2006) Optics Letters , vol.31 , Issue.24 , pp. 3656-3658
    • Burkacky, O.1    Zumbusch, A.2    Brackmann, C.3    Enejder, A.4
  • 30
    • 58149306055 scopus 로고    scopus 로고
    • Quantitative label-free imaging of lipid composition and packing of individual cellular lipid droplets using multiplex CARS microscopy
    • Rinia, H. A., Burger, K. N. J., Bonn, M. and Muller, M., "Quantitative label-free imaging of lipid composition and packing of individual cellular lipid droplets using multiplex CARS microscopy," Biophys. J. 95, 4908-4918 (2008).
    • (2008) Biophys. J. , vol.95 , pp. 4908-4918
    • Rinia, H.A.1    Burger, K.N.J.2    Bonn, M.3    Muller, M.4
  • 32
    • 33847707430 scopus 로고    scopus 로고
    • In vivo coherent anti-Stokes Raman scattering imaging of sciatic nerve tissue
    • DOI 10.1111/j.1365-2818.2007.01729.x
    • Huff, T. B. and Cheng, J. X., "In vivo coherent anti-Stokes Raman scattering imaging of sciatic nerve tissue," J. Microsc. 225, 175-182 (2007). (Pubitemid 46376190)
    • (2007) Journal of Microscopy , vol.225 , Issue.2 , pp. 175-182
    • Huff, T.B.1    Cheng, J.-X.2
  • 33
    • 44449095056 scopus 로고    scopus 로고
    • Functional genomic screen reveals genes involved in lipid-droplet formation and utilization
    • DOI 10.1038/nature06928, PII NATURE06928
    • Guo, Y., Walther, T. C., Rao, M., Stuurman, N., Goshima, G., Terayama, K., Wong, J. S., Vale, R. D., Walter, P. and Farese, R. V., "Functional genomic screen reveals genes involved in lipiddroplet formation and utilization," Nature 453, 657-661 (2008). (Pubitemid 351769298)
    • (2008) Nature , vol.453 , Issue.7195 , pp. 657-661
    • Guo, Y.1    Walther, T.C.2    Rao, M.3    Stuurman, N.4    Goshima, G.5    Terayama, K.6    Wong, J.S.7    Vale, R.D.8    Walter, P.9    Farese Jr., R.V.10
  • 35
    • 30944467113 scopus 로고    scopus 로고
    • A guide to choosing fluorescent proteins
    • DOI 10.1038/nmeth819, PII N819
    • Shaner, N. C., Steinbach, P. A. and Tsien, R. Y., "A guide to choosing fluorescent proteins," Nat. Methods 2, 905-909 (2005). (Pubitemid 43108726)
    • (2005) Nature Methods , vol.2 , Issue.12 , pp. 905-909
    • Shaner, N.C.1    Steinbach, P.A.2    Tsien, R.Y.3
  • 36
    • 33748304273 scopus 로고    scopus 로고
    • Dynamics of heat shock factor association with native gene loci in living cells
    • DOI 10.1038/nature05025, PII NATURE05025
    • Yao, J., Munson, K. M., Webb, W. W. and Lis, J. T., "Dynamics of heat shock factor association with native gene loci in living cells," Nature 442, 1050-1053 (2006). (Pubitemid 44330263)
    • (2006) Nature , vol.442 , Issue.7106 , pp. 1050-1053
    • Yao, J.1    Munson, K.M.2    Webb, W.W.3    Lis, J.T.4
  • 38
  • 39
    • 34347237194 scopus 로고    scopus 로고
    • Fluorescence correlation spectroscopy: Novel variations of an established technique
    • DOI 10.1146/annurev.biophys.36.040306.132612
    • Haustein, E. and Schwille, P., "Fluorescence correlation spectroscopy: Novel variations of an established technique," Annu. Rev. Biophys. Biomol. Struct. 36, 151-169 (2007). (Pubitemid 46998114)
    • (2007) Annual Review of Biophysics and Biomolecular Structure , vol.36 , pp. 151-169
    • Haustein, E.1    Schwille, P.2
  • 40
    • 33646168160 scopus 로고    scopus 로고
    • Lipid droplets: A unified view of a dynamic organelle
    • Martin, S. and Parton, R. G., "Lipid droplets: A unified view of a dynamic organelle," Nat. Rev. Mol. Cell. Biol. 7, 373-378 (2006).
    • (2006) Nat. Rev. Mol. Cell. Biol. , vol.7 , pp. 373-378
    • Martin, S.1    Parton, R.G.2
  • 41
    • 0345900899 scopus 로고    scopus 로고
    • Paracrine regulation of angiogenesis and adipocyte differentiation during in vivo adipogenesis
    • Fukumura, D. et al., "Paracrine regulation of angiogenesis and adipocyte differentiation during in vivo adipogenesis," Circ. Res. 93, 88-97 (2003).
    • (2003) Circ. Res. , vol.93 , pp. 88-97
    • Fukumura, D.1
  • 42
    • 0034918106 scopus 로고    scopus 로고
    • In vivo measurement of gene expression, angiogenesis and physiological function in tumors using multiphoton laser scanning microscopy
    • DOI 10.1038/89997
    • Brown, E. B., Campbell, R. B., Tsuzuki, Y., Xu, L., Carmeliet, P., Fukumura, D. and Jain, R. K., "In vivo measurement of gene expression, angiogenesis and physiological function in tumors using multiphoton laser scanning microscopy," Nat. Med. 7, 864-868 (2001). (Pubitemid 32691644)
    • (2001) Nature Medicine , vol.7 , Issue.7 , pp. 864-868
    • Brown, E.B.1    Campbell, R.B.2    Tsuzuki, Y.3    Xu, L.4    Carmeliet, P.5    Fukumura, D.6    Jain, R.K.7
  • 43
    • 1642633760 scopus 로고    scopus 로고
    • Two-photon fluorescence correlation microscopy reveals the two-phase nature of transport in tumors
    • DOI 10.1038/nm981
    • Alexandrakis, G., Brown, E. B., Tang, R. T., Mckee, T. D., Campbell, R. B., Boucher, Y. and Jain R. K., "Two-photon fluorescence correlation microscopy reveals the two-phase nature of transport in tumors," Nat. Med. 10, 203-207 (2004). (Pubitemid 38524893)
    • (2004) Nature Medicine , vol.10 , Issue.2 , pp. 203-207
    • Alexandrakis, G.1    Brown, E.B.2    Tong, R.T.3    McKee, T.D.4    Campbell, R.B.5    Boucher, Y.6    Jain, R.K.7
  • 45
    • 33745223646 scopus 로고    scopus 로고
    • Finding function in novel targets: C-elegans as a model organism
    • Kaletta, T. and Hengartner, M. O., "Finding function in novel targets: C-elegans as a model organism," Nat. Rev. Drug Discovery 5, 387-398 (2006).
    • (2006) Nat. Rev. Drug Discovery , vol.5 , pp. 387-398
    • Kaletta, T.1    Hengartner, M.O.2
  • 46
    • 0036403778 scopus 로고    scopus 로고
    • Developmental genomic approaches in model organisms
    • DOI 10.1146/annurev.genom.3.031302.100922
    • Reinke, V. and White, K. P., "Developmental genomic approaches in model organisms," Annu. Rev. Genomics Hum. Genet. 3, 153-178 (2002). (Pubitemid 35217434)
    • (2002) Annual Review of Genomics and Human Genetics , vol.3 , pp. 153-178
    • Reinke, V.1    White, K.P.2
  • 47
    • 12144273121 scopus 로고    scopus 로고
    • In vivo drug discovery in the zebrafish
    • DOI 10.1038/nrd1606
    • Zon, L. I. and Peterson, R. T., "In vivo drug discovery in the zebrafish," Nat. Rev. Drug Discovery 4, 35-44 (2005). (Pubitemid 40109588)
    • (2005) Nature Reviews Drug Discovery , vol.4 , Issue.1 , pp. 35-44
    • Zon, L.I.1    Peterson, R.T.2
  • 50
    • 33745106287 scopus 로고    scopus 로고
    • Molecular links between obesity and breast cancer
    • DOI 10.1677/erc.1.00729
    • Lorincz, A. M. and Sukumar, S., Molecular links between obesity and breast cancer," Endocr. Relat. Cancer. 13, 279-292 (2006). (Pubitemid 43886659)
    • (2006) Endocrine-Related Cancer , vol.13 , Issue.2 , pp. 279-292
    • Lorincz, A.M.1    Sukumar, S.2
  • 51
    • 0142103807 scopus 로고    scopus 로고
    • Adipocyte-secreted factors synergistically promote mammary tumorigenesis through induction of anti-apoptotic transcriptional programs and proto-oncogene stabilization
    • DOI 10.1038/sj.onc.1206737
    • Iyengar, P., Combs, T. P., Shah, S. J., Gauon-Evans, V., Pollard, J. W., Albanese, C., Flanagan, L., Tenniswood, M. P., Guha, C., Lisanti, M. P., Pestell, R. G. and Scherer, P. E., "Adipocytesecreted factors synergistically promote mammary tumorigenesis through induction of anti-apoptotic transcriptional programs and proto-oncogene stabilization," Oncogene 22, 6408-6423 (2003). (Pubitemid 37281689)
    • (2003) Oncogene , vol.22 , Issue.41 , pp. 6408-6423
    • Iyengar, P.1    Combs, T.P.2    Shah, S.J.3    Gouon-Evans, V.4    Pollard, J.W.5    Albanese, C.6    Flanagan, L.7    Tenniswood, M.P.8    Guha, C.9    Lisanti, M.P.10    Pestell, R.G.11    Scherer, P.E.12
  • 52
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan, D. and Weinberg, R. A., "The hallmarks of cancer," Cell 100, 57-70 (2000). (Pubitemid 30046295)
    • (2000) Cell , vol.100 , Issue.1 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 53
    • 0035495401 scopus 로고    scopus 로고
    • Putting tumours in context
    • Bissell, M. J. and Radisky, D., "Putting tumours in context," Nat. Rev. Cancer 1, 46-54 (2001). (Pubitemid 33741880)
    • (2001) Nature Reviews Cancer , vol.1 , Issue.1 , pp. 46-54
    • Bissell, M.J.1    Radisky, D.2
  • 54
    • 33645739790 scopus 로고    scopus 로고
    • Tumor stroma and regulation of cancer development
    • Tlsty, T. D. and Coussens, L. M., "Tumor stroma and regulation of cancer development," Annu. Rev. Pathol. Mech. Dis. 1, 119-150 (2006).
    • (2006) Annu. Rev. Pathol. Mech. Dis. , vol.1 , pp. 119-150
    • Tlsty, T.D.1    Coussens, L.M.2
  • 61
    • 34547259283 scopus 로고    scopus 로고
    • Nonlinear optical imaging to evaluate the impact of obesity on mammary gland and tumor stroma
    • DOI 10.2310/7290.2007.00018
    • Le, T. T., Rehrer, C. W., Huff, T. B., Nichols, M. B., Camarillo, I. G. and Chen, J. X., "Nonlinear optical imaging to evaluate the impact of obesity on mammary gland and tumor stroma," Mol. Imaging 6, 205-211 (2007). (Pubitemid 47152707)
    • (2007) Molecular Imaging , vol.6 , Issue.3 , pp. 205-211
    • Le, T.T.1    Rehrer, C.W.2    Huff, T.B.3    Nichais, M.B.4    Camarilla, I.G.5    Cheng, J.-X.6
  • 64
    • 0025990740 scopus 로고
    • Transcriptional activity of the α1(I)-collagen promoter is correlated with the formation of capillary-like structures by endothelial cells in vitro
    • Fouser, L., Iruelaarispe, L., Bornstein, P. and Sage, E. H., "Transcriptional activity of the α-1(I)-collagen promoter is correlated with the formation of capillary-like structures by endothelial cells in vitro," J. Biol. Chem. 266, 18345-18351 (1991). (Pubitemid 21908086)
    • (1991) Journal of Biological Chemistry , vol.266 , Issue.27 , pp. 18345-18351
    • Fouser, L.1    Iruela-Arispe, L.2    Bornstein, P.3    Sage, E.H.4
  • 66
    • 0032829513 scopus 로고    scopus 로고
    • Confocal imaging of microglial cell dynamics in hippocampal slice cultures
    • DOI 10.1006/meth.1999.0775
    • Dailey, M. E. and Waite, M., "Confocal imaging of microglial cell dynamics in hippocampal slice cultures," Methods 18, 222-230 (1999). (Pubitemid 29443838)
    • (1999) Methods: A Companion to Methods in Enzymology , vol.18 , Issue.2 , pp. 222-230
    • Dailey, M.E.1    Waite, M.2
  • 67
    • 34247857663 scopus 로고    scopus 로고
    • Obesity, inflammation, and insulin resistance
    • DOI 10.1053/j.gastro.2007.03.059, PII S0016508507005859
    • Shoelson, S. E., Herrero, L. and Naaz, A., "Obesity, inflammation, and insulin resistance," Gastroenterology 132, 2169-2180 (2007). (Pubitemid 46693756)
    • (2007) Gastroenterology , vol.132 , Issue.6 , pp. 2169-2180
    • Shoelson, S.E.1    Herrero, L.2    Naaz, A.3
  • 68
    • 0026002576 scopus 로고
    • Effect of dietary fat on human breast cancer growth and lung metastasis in nude mice
    • Rose, D. P., Connolly, J. M. and Meschte, C. L., "Effect of dietary fat on human breast cancer growth and lung metastasis in nude mice," J. Natl. Cancer Inst. 83, 1491-1495 (1991).
    • (1991) J. Natl. Cancer Inst. , vol.83 , pp. 1491-1495
    • Rose, D.P.1    Connolly, J.M.2    Meschte, C.L.3
  • 71
    • 0016379208 scopus 로고
    • Lipid-rich carcinoma of the breast: A clinicopathologic analysis of 13 examples
    • Ramos, C. V. and Taylor, H. B., "Lipid-rich carcinoma of the breast: A clinicopathologic analysis of 13 examples," Cancer 33, 812-819 (1973).
    • (1973) Cancer , vol.33 , pp. 812-819
    • Ramos, C.V.1    Taylor, H.B.2
  • 73
    • 0029658382 scopus 로고    scopus 로고
    • 1H MR spectroscopy detection of lipids and lactate in metastatic brain tumors
    • DOI 10.1002/(SICI)1099-1492(199604)9:2<65::AID-NBM397>3.0.CO;2-N
    • Sijens, P. E., Levendag, P. C., Vecht, C. J., vanDijk, P. and Oudkerk, M., "H-1 MR spectroscopy detection of lipids and lactate in metastatic brain tumors," NMR Biomed. 9, 65-71 (1996). (Pubitemid 26352495)
    • (1996) NMR in Biomedicine , vol.9 , Issue.2 , pp. 65-71
    • Sijens, P.E.1    Levendag, P.C.2    Vecht, C.J.3    Van Dijk, P.4    Oudkerk, M.5
  • 74
    • 51649111485 scopus 로고    scopus 로고
    • Optical contrast agents and imaging systems for detection and diagnosis of cancer
    • Pierce, M. C., Javier, D. J. and Richards-Kortum, R., "Optical contrast agents and imaging systems for detection and diagnosis of cancer," Int. J. Cancer 123, 1979-1990 (2008).
    • (2008) Int. J. Cancer , vol.123 , pp. 1979-1990
    • Pierce, M.C.1    Javier, D.J.2    Richards-Kortum, R.3
  • 75
    • 0030760309 scopus 로고    scopus 로고
    • In vivo endoscopic optical biopsy with optical coherence tomography
    • DOI 10.1126/science.276.5321.2037
    • Tearney, G. J., Brezinski, M. E., Bouma, B. E., Boppart, S. A., Pitris, C., Southern, J. F. and Fujimoto, J. G., "In vivo endoscopic optical biopsy with optical coherence tomography," Science 276, 2037-2039 (1997). (Pubitemid 27443607)
    • (1997) Science , vol.276 , Issue.5321 , pp. 2037-2039
    • Tearney, G.J.1    Brezinski, M.E.2    Bouma, B.E.3    Boppart, S.A.4    Pitris, C.5    Southern, J.F.6    Fujimoto, J.G.7
  • 76
    • 44349142770 scopus 로고    scopus 로고
    • Assessing the future of diffuse optical imaging technologies for breast cancer management
    • DOI 10.1118/1.2919078
    • Tromberg, B. J., Pogue, B. W., Paulsen, K. D., Yodh, A. G., Boas, D. A. and Cerussi, A. E., "Assessing the future of diffuse optical imaging technologies for breast cancer management," Med. Phys. 35, 2443-2451 (2008). (Pubitemid 351748652)
    • (2008) Medical Physics , vol.35 , Issue.6 , pp. 2443-2451
    • Tromberg, B.J.1    Pogue, B.W.2    Paulsen, K.D.3    Yodh, A.G.4    Boas, D.A.5    Cerussi, A.E.6
  • 78
    • 0036852699 scopus 로고    scopus 로고
    • Stabilization of atherosclerotic plaques: New mechanisms and clinical targets
    • DOI 10.1038/nm1102-1257
    • Libby, P. and Aikawa, M., "Stabilization of atherosclerotic plaques: New mechanisms and clinical targets," Nat. Med. 8, 1257-1262 (2002). (Pubitemid 35373557)
    • (2002) Nature Medicine , vol.8 , Issue.11 , pp. 1257-1262
    • Libby, P.1    Aikawa, M.2
  • 79
    • 0035811026 scopus 로고    scopus 로고
    • High prevalence of coronary atherosclerosis in asymptomatic teenagers and young adults evidence from intravascular ultrasound
    • Tuzcu, E. M., Kapadia, S. R., Tutar, E., Ziada, K. M., Hobbs, R. E., McCarthy, P. M., Young, J. B. and Nissen, S. E., "High prevalence of coronary atherosclerosis in asymptomatic teenagers and young adults-Evidence from intravascular ultrasound," Circulation 103, 2705-2710 (2001). (Pubitemid 32538786)
    • (2001) Circulation , vol.103 , Issue.22 , pp. 2705-2710
    • Tuzcu, E.M.1    Kapadia, S.R.2    Tutar, E.3    Ziada, K.M.4    Hobbs, R.E.5    McCarthy, P.M.6    Young, J.B.7    Nissen, S.E.8
  • 80
    • 0034019601 scopus 로고    scopus 로고
    • Lessons from sudden coronary death: A comprehensive morphological classification scheme for atherosclerotic lesions
    • Virmani, R., Kolodgie, F., Burke, A. P., Farb, A. and Schwartz, S. M., "Lessons from sudden coronary death-A comprehensive morphological classification scheme for atherosclerotic lesions," Arterioscler. Thromb. Vasc. Biol. 20, 1262-1275 (2000). (Pubitemid 30262927)
    • (2000) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.20 , Issue.5 , pp. 1262-1275
    • Virmani, R.1    Kolodgie, F.D.2    Burke, A.P.3    Farb, A.4    Schwartz, S.M.5
  • 81
    • 0036853543 scopus 로고    scopus 로고
    • Atherogenesis in perspective: Hypercholesterolemia and inflammation as partners in crime
    • DOI 10.1038/nm1102-1211
    • Steinberg, D., "Atherogenesis in perspective: Hypercholesterolemia and inflammation as partners in crime," Nature Med. 8, 1211-1217 (2002). (Pubitemid 35373551)
    • (2002) Nature Medicine , vol.8 , Issue.11 , pp. 1211-1217
    • Steinberg, D.1
  • 82
    • 0034648768 scopus 로고    scopus 로고
    • Atherosclerosis
    • Lusis, A. J., "Atherosclerosis," Nature 407, 233-241 (2000).
    • (2000) Nature , vol.407 , pp. 233-241
    • Lusis, A.J.1
  • 83
    • 0027253887 scopus 로고
    • Risk of thrombosis in human atherosclerotic plaques: Role of extracellular lipid, macrophage, and smooth muscle cell content
    • Davies, M. J., Richardson, P. D., Woolf, N., Katz, D. R. and Mann, J., "Risk of thrombosis in human atherosclerotic plaques-role of extracellular lipid, macrophage, and smooth-muscle cell content," Br. Heart. J. 69, 377-381 (1993). (Pubitemid 23171108)
    • (1993) British Heart Journal , vol.69 , Issue.5 , pp. 377-381
    • Davies, M.J.1    Richardson, P.D.2    Woolf, N.3    Katz, D.R.4    Mann, J.5
  • 84
    • 8844232710 scopus 로고    scopus 로고
    • Molecular, cellular and functional imaging of atherothrombosis
    • DOI 10.1038/nrd1548
    • Choudhury, R. P., Fuster, V. and Fayad, Z. A., "Molecular, cellular and functional imaging of atherothrombosis," Nat. Rev. Drug. Discov. 3, 913-925 (2004). (Pubitemid 39529929)
    • (2004) Nature Reviews Drug Discovery , vol.3 , Issue.11 , pp. 913-925
    • Choudhary, R.P.1    Fuster, V.2    Fayad, Z.A.3
  • 85
    • 0035720530 scopus 로고    scopus 로고
    • Discrimination of human coronary artery atherosclerotic lipid-rich lesions by time-resolved laser-induced fluorescence spectroscopy
    • Marcu, L., Fishbein, M. C., Maarek, J. M. I. and Grundfest, W. S., "Discrimination of human coronary artery atherosclerotic lipid-rich lesions by time-resolved laser-induced fluorescence spectroscopy," Arterioscler. Thromb. Vasc. Biol. 21, 1244-1250 (2001). (Pubitemid 34215158)
    • (2001) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.21 , Issue.7 , pp. 1244-1250
    • Marcu, L.1    Fishbein, M.C.2    Maarek, J.-M.I.3    Grundfest, W.S.4
  • 88
    • 0035011098 scopus 로고    scopus 로고
    • Direct viewing of atherosclerosis in vivo: Plaque invasion by leukocytes is initiated by the endothelial selectins
    • DOI 10.1096/fj.00-0537com
    • Eriksson, E. E., Xie, X., Werr, J., Thoren, P. and Lindbom, L., "Direct viewing of atherosclerosis in vivo: plaque invasion by leukocytes is initiated by the endothelial selectins," FASEB J. 15, 1149-1157 (2001). (Pubitemid 32436300)
    • (2001) FASEB Journal , vol.15 , Issue.7 , pp. 1149-1157
    • Eriksson, E.E.1    Xie, X.2    Werr, J.3    Thoren, P.4    Lindbom, L.5
  • 89
    • 0037231665 scopus 로고    scopus 로고
    • Circulating activated platelets exacerbate atherosclerosis in mice deficient in apolipoprotein E
    • DOI 10.1038/nm810
    • Huo, Y. Q., Schober, A., Forlow, S. B., Smith, D. F., Hyman, M. C., Jung, S., Littman, D. R., Weber, C. and Ley, K., "Circulating activated platelets exacerbate atherosclerosis in mice deficient in apolipoprotein E," Nature Med. 9, 61-67 (2003). (Pubitemid 36098261)
    • (2003) Nature Medicine , vol.9 , Issue.1 , pp. 61-67
    • Huo, Y.1    Schober, A.2    Forlow, S.B.3    Smith, D.F.4    Hyman, M.C.5    Jung, S.6    Littman, D.R.7    Weber, C.8    Ley, K.9
  • 90
    • 14944380678 scopus 로고    scopus 로고
    • Imaging coronary artery microstructure using second-harmonic and two-photon fluorescence microscopy
    • Zoumi, A., Lu, X. A., Kassab, G. S. and Tromberg, B. J., "Imaging coronary artery microstructure using second-harmonic and two-photon fluorescence microscopy," Biophys. J. 87, 2778-2786 (2004).
    • (2004) Biophys. J. , vol.87 , pp. 2778-2786
    • Zoumi, A.1    Lu, X.A.2    Kassab, G.S.3    Tromberg, B.J.4
  • 91
    • 38449102862 scopus 로고    scopus 로고
    • In vivo imaging of atherosclerotic plaques in apolipoprotein e deficient mice using nonlinear microscopy
    • Yu, W. M., Braz, J. C., Dutton, A. M., Prusakov, P. and Rekhter, M., "In vivo imaging of atherosclerotic plaques in apolipoprotein E deficient mice using nonlinear microscopy," J. Biomed. Opt. 12, 054008 (2007).
    • (2007) J. Biomed. Opt. , vol.12 , pp. 054008
    • Yu, W.M.1    Braz, J.C.2    Dutton, A.M.3    Prusakov, P.4    Rekhter, M.5
  • 93
    • 38449092255 scopus 로고    scopus 로고
    • Label-free molecular imaging of atherosclerotic lesions using multimodal nonlinear optical microscopy
    • Le, T. T., Langohr, I. M., Locker, M. J., Sturek, M. and Cheng, J. X., "Label-free molecular imaging of atherosclerotic lesions using multimodal nonlinear optical microscopy," J. Biomed. Opt. 12, 054007 (2007).
    • (2007) J. Biomed. Opt. , vol.12 , pp. 054007
    • Le, T.T.1    Langohr, I.M.2    Locker, M.J.3    Sturek, M.4    Cheng, J.X.5
  • 94
    • 39449103332 scopus 로고    scopus 로고
    • Label-free imaging of arterial cells and extracellular matrix using a multimodal CARS microscope
    • DOI 10.1016/j.optcom.2007.07.067, PII S0030401807010723
    • Wang, H. W., Le, T. T. and Cheng, J. X., "Labelfree imaging of arterial cells and extracellular matrix using a multimodal CARS microscope," Opt. Comm. 281, 1813-1822 (2008). (Pubitemid 351274127)
    • (2008) Optics Communications , vol.281 , Issue.7 , pp. 1813-1822
    • Wang, H.-W.1    Le, T.T.2    Cheng, J.-X.3
  • 95
    • 23244460036 scopus 로고    scopus 로고
    • Coherent anti-stokes Raman scattering imaging of axonal myelin in live spinal tissues
    • DOI 10.1529/biophysj.105.061911
    • Wang, H. F., Fu, Y., Zickmund, P., Shi, R. Y. and Cheng, J. X., "Coherent anti-stokes Raman scattering imaging of axonal myelin in live spinal tissues," Biophys. J. 89, 581-591 (2005). (Pubitemid 41098311)
    • (2005) Biophysical Journal , vol.89 , Issue.1 , pp. 581-591
    • Wang, H.1    Fu, Y.2    Zickmund, P.3    Shi, R.4    Cheng, J.-X.5
  • 96
    • 25144469422 scopus 로고    scopus 로고
    • Mechanisms of axon ensheathment and myelin growth
    • DOI 10.1038/nrn1743, PII NRN1743
    • Sherman, D. L. and Brophy, P. J., "Mechanisms of axon ensheathment and myelin growth," Nat. Rev. Neurosci. 6, 683-690 (2005). (Pubitemid 43160317)
    • (2005) Nature Reviews Neuroscience , vol.6 , Issue.9 , pp. 683-690
    • Sherman, D.L.1    Brophy, P.J.2
  • 97
    • 17644396349 scopus 로고    scopus 로고
    • Immunology of multiple sclerosis
    • DOI 10.1146/annurev.immunol.23.021704.115707
    • Sospedra, M. and Martin, R., "Immunology of multiple sclerosis," Annu. Rev. Immunol. 23, 683-747 (2005). (Pubitemid 40563183)
    • (2005) Annual Review of Immunology , vol.23 , pp. 683-747
    • Sospedra, M.1    Martin, R.2
  • 98
    • 34948847552 scopus 로고    scopus 로고
    • Coherent anti-Stokes Raman scattering imaging of myelin degradation reveals a calcium-dependent pathway in lyso-PtdCho-induced demyelination
    • DOI 10.1002/jnr.21403
    • Fu, Y., Wang, H. F., Huff, T. B., Shi, R. and Cheng, J. X., "Coherent anti-stokes Raman scattering imaging of myelin degradation reveals a calcium-dependent pathway in lyso-PtdChoinduced demyelination," J. Neurosci. Res. 85, 2870-2881 (2007). (Pubitemid 47523571)
    • (2007) Journal of Neuroscience Research , vol.85 , Issue.13 , pp. 2870-2881
    • Fu, Y.1    Wang, H.2    Huff, T.B.3    Shi, R.4    Cheng, J.-X.5
  • 99
    • 34648831771 scopus 로고    scopus 로고
    • Chemically-selective imaging of brain structures with CARS microscopy
    • DOI 10.1364/OE.15.012076
    • Evans, C. L., Xu, X., Kesari, S., Xie, X. S., Wong, S. T. C. and Young. G. S., "Chemically selective imaging of brain structures with CARS microscopy," Opt. Express. 15, 12076-12087 (2007). (Pubitemid 47460072)
    • (2007) Optics Express , vol.15 , Issue.19 , pp. 12076-12087
    • Evans, C.L.1    Xu, X.2    Kesari, S.3    Xie, X.S.4    Wong, S.T.C.5    Young, G.S.6
  • 100
    • 57149132073 scopus 로고    scopus 로고
    • Ex vivo and in vivo imaging of myelin fibers in mouse brain by coherent anti-Stokes Raman microscopy
    • Fu, Y., Huff, T. B., Wang, H. W., Wang, H. F. and Cheng, J. X., "Ex vivo and in vivo imaging of myelin fibers in mouse brain by coherent anti-Stokes Raman microscopy," Opt. Express. 16, 19396-19409 (2008).
    • (2008) Opt. Express. , vol.16 , pp. 19396-19409
    • Fu, Y.1    Huff, T.B.2    Wang, H.W.3    Wang, H.F.4    Cheng, J.X.5
  • 101
    • 0038649993 scopus 로고    scopus 로고
    • Combined in vivo confocal Raman spectroscopy and confocal microscopy of human skin
    • Caspers, P. J., Lucassen, G.W. and Puppels, G. J., "Combined in vivo confocal Raman spectroscopy and confocal microscopy of human skin," Biophys. J. 85, 572-580 (2003). (Pubitemid 36753659)
    • (2003) Biophysical Journal , vol.85 , Issue.1 , pp. 572-580
    • Caspers, P.J.1    Lucassen, G.W.2    Puppels, G.J.3
  • 102
    • 38949218032 scopus 로고    scopus 로고
    • Sebaceous gland lipids: Friend or foe?
    • Smith, K. R. and Thiboutot, D. M., "Sebaceous gland lipids: Friend or foe?," J. Lipid. Res. 49, 271-281 (2008).
    • (2008) J. Lipid. Res. , vol.49 , pp. 271-281
    • Smith, K.R.1    Thiboutot, D.M.2
  • 103
    • 33646551017 scopus 로고    scopus 로고
    • Broadly tunable dual-wavelength light source for coherent anti-Stokes Raman scattering microscopy
    • DOI 10.1364/OL.31.001292
    • Ganikhanov, F., Carrasco, S., Xie, X. S., Katz, M., Seitz, W. and Kopf, D., "Broadly tunable dual-wavelength light source for coherent anti-Stokes Raman scattering microscopy," Opt. Lett. 31, 1292-1294 (2006). (Pubitemid 43901270)
    • (2006) Optics Letters , vol.31 , Issue.9 , pp. 1292-1294
    • Ganikhanov, F.1    Carrasco, S.2    Xie, X.S.3    Katz, M.4    Seitz, W.5    Kopf, D.6
  • 105
    • 33646582630 scopus 로고    scopus 로고
    • Towards CARS endoscopy
    • DOI 10.1364/OE.14.004427
    • Legare, F., Evans, C. L., Ganikhanov, F. and Xie, X. S., "Towards CARS endoscopy," Opt. Express. 14, 4427-4432 (2006). (Pubitemid 43727632)
    • (2006) Optics Express , vol.14 , Issue.10 , pp. 4427-4432
    • Legare, F.1    Evans, C.L.2    Ganikhanov, F.3    Xie, X.S.4
  • 106
    • 49649100130 scopus 로고    scopus 로고
    • Minimally invasive highspeed imaging of sarcomere contractile dynamics in mice and humans
    • Llewellyn, M. E., Barretto, R. P. J., Delp, S. L. and Schnitzer, M. J., "Minimally invasive highspeed imaging of sarcomere contractile dynamics in mice and humans," Nature 454, 784-788 (2008).
    • (2008) Nature , vol.454 , pp. 784-788
    • Llewellyn, M.E.1    Barretto, R.P.J.2    Delp, S.L.3    Schnitzer, M.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.