-
1
-
-
58249088751
-
MicroRNAs: target recognition and regulatory functions
-
Bartel D.P. MicroRNAs: target recognition and regulatory functions. Cell 136 (2009) 215-233
-
(2009)
Cell
, vol.136
, pp. 215-233
-
-
Bartel, D.P.1
-
2
-
-
67651002343
-
Emerging roles of microRNAs as molecular switches in the integrated circuit of the cancer cell
-
Sotiropoulou G., Pampalakis G., and Lianidou E. Emerging roles of microRNAs as molecular switches in the integrated circuit of the cancer cell. RNA 15 (2009) 1443-1461
-
(2009)
RNA
, vol.15
, pp. 1443-1461
-
-
Sotiropoulou, G.1
Pampalakis, G.2
Lianidou, E.3
-
3
-
-
48249104039
-
Riboswitches: emerging themes in RNA structure and function
-
Montange R.K., and Batey R.T. Riboswitches: emerging themes in RNA structure and function. Annu Rev Biophys 37 (2008) 117-133
-
(2008)
Annu Rev Biophys
, vol.37
, pp. 117-133
-
-
Montange, R.K.1
Batey, R.T.2
-
4
-
-
51449085579
-
Origins and evolution of eukaryotic RNA interference
-
Shabalina S.A., and Koonin E.V. Origins and evolution of eukaryotic RNA interference. Trends Ecol Evolut 23 (2008) 578-587
-
(2008)
Trends Ecol Evolut
, vol.23
, pp. 578-587
-
-
Shabalina, S.A.1
Koonin, E.V.2
-
5
-
-
0020417286
-
Self-splicing RNA: autoexcision and autocyclization of the ribosomal RNA intervening sequence of the Tetrahymena
-
Kruger K., Grabowski P.J., Zaug A.J., Sands J., Gottschling D.E., and Cech T.R. Self-splicing RNA: autoexcision and autocyclization of the ribosomal RNA intervening sequence of the Tetrahymena. Cell 31 (1982) 147-157
-
(1982)
Cell
, vol.31
, pp. 147-157
-
-
Kruger, K.1
Grabowski, P.J.2
Zaug, A.J.3
Sands, J.4
Gottschling, D.E.5
Cech, T.R.6
-
6
-
-
0021013526
-
The RNA moiety of the ribonuclease P is the catalytic subunit of the enzyme
-
Guerrier-Takada C., Gardiner K., Marsh T., Pace N., and Altman S. The RNA moiety of the ribonuclease P is the catalytic subunit of the enzyme. Cell 35 (1983) 848-857
-
(1983)
Cell
, vol.35
, pp. 848-857
-
-
Guerrier-Takada, C.1
Gardiner, K.2
Marsh, T.3
Pace, N.4
Altman, S.5
-
7
-
-
57649089373
-
Experimental analyses of the chemical dynamics of ribozyme catalysis
-
Harris M.E., and Cassano A.G. Experimental analyses of the chemical dynamics of ribozyme catalysis. Curr Opin Chem Biol 12 (2008) 626-639
-
(2008)
Curr Opin Chem Biol
, vol.12
, pp. 626-639
-
-
Harris, M.E.1
Cassano, A.G.2
-
8
-
-
33745311268
-
Re-creating an RNA world
-
Muller U.F. Re-creating an RNA world. Cell Mol Life Sci 63 (2006) 1278-1293
-
(2006)
Cell Mol Life Sci
, vol.63
, pp. 1278-1293
-
-
Muller, U.F.1
-
9
-
-
0001571550
-
Autolytic processing of dimeric plant virus satellite RNA
-
Prody G.A., Bakos J.T., Buzayan J.M., Schneider I.R., and Bruening G. Autolytic processing of dimeric plant virus satellite RNA. Science 231 (1986) 1577-1580
-
(1986)
Science
, vol.231
, pp. 1577-1580
-
-
Prody, G.A.1
Bakos, J.T.2
Buzayan, J.M.3
Schneider, I.R.4
Bruening, G.5
-
10
-
-
0023663396
-
Self-cleavage of plus and minus RNAs of a virusoid and a structural model for the active sites
-
Forster A.C., and Symons R.H. Self-cleavage of plus and minus RNAs of a virusoid and a structural model for the active sites. Cell 49 (1987) 211-220
-
(1987)
Cell
, vol.49
, pp. 211-220
-
-
Forster, A.C.1
Symons, R.H.2
-
11
-
-
0026651086
-
Small catalytic RNAs
-
Symons R.H. Small catalytic RNAs. Annu Rev Biochem 61 (1992) 641-671
-
(1992)
Annu Rev Biochem
, vol.61
, pp. 641-671
-
-
Symons, R.H.1
-
12
-
-
51649103765
-
Catalytic strategies of self-cleaving ribozymes
-
Cochrane J.C., and Strobel S.A. Catalytic strategies of self-cleaving ribozymes. Acc Chem Res 41 (2008) 1027-1035
-
(2008)
Acc Chem Res
, vol.41
, pp. 1027-1035
-
-
Cochrane, J.C.1
Strobel, S.A.2
-
13
-
-
33748559498
-
Nucleobase catalysis in ribozyme mechanism
-
Bevilacqua P.C., and Yajima R. Nucleobase catalysis in ribozyme mechanism. Curr Opin Chem Biol 10 (2006) 455-464
-
(2006)
Curr Opin Chem Biol
, vol.10
, pp. 455-464
-
-
Bevilacqua, P.C.1
Yajima, R.2
-
14
-
-
0023221419
-
A small catalytic oligoribonucleotide
-
Uhlenbeck O.C. A small catalytic oligoribonucleotide. Nature 328 (1987) 596-600
-
(1987)
Nature
, vol.328
, pp. 596-600
-
-
Uhlenbeck, O.C.1
-
15
-
-
0024291288
-
Simple RNA ribozymes with new and highly specific endoribonuclease activities
-
Haseloff J., and Gerlach W.L. Simple RNA ribozymes with new and highly specific endoribonuclease activities. Nature 334 (1988) 585-591
-
(1988)
Nature
, vol.334
, pp. 585-591
-
-
Haseloff, J.1
Gerlach, W.L.2
-
16
-
-
0030939002
-
The structure, function and application of the hammerhead ribozyme
-
Birikh K.R., Heaton P.A., and Eckstein F. The structure, function and application of the hammerhead ribozyme. Eur J Biochem 245 (1997) 1-16
-
(1997)
Eur J Biochem
, vol.245
, pp. 1-16
-
-
Birikh, K.R.1
Heaton, P.A.2
Eckstein, F.3
-
17
-
-
0028063567
-
Three-dimensional structure of a hammerhead ribozyme
-
Pley H.W., Flaherty K.M., and McKay D.B. Three-dimensional structure of a hammerhead ribozyme. Nature 372 (1994) 68-74
-
(1994)
Nature
, vol.372
, pp. 68-74
-
-
Pley, H.W.1
Flaherty, K.M.2
McKay, D.B.3
-
18
-
-
0029073091
-
The crystal structure of an all-RNA hammerhead ribozyme a proposed mechanism for RNA catalytic cleavage
-
Scott W.G., Finch J.T., and Klug A. The crystal structure of an all-RNA hammerhead ribozyme a proposed mechanism for RNA catalytic cleavage. Cell 81 (1995) 991-1002
-
(1995)
Cell
, vol.81
, pp. 991-1002
-
-
Scott, W.G.1
Finch, J.T.2
Klug, A.3
-
19
-
-
19644363114
-
The structure-function dilemma of the hammerhead ribozyme
-
Blount K.B., and Uhlenbeck O.C. The structure-function dilemma of the hammerhead ribozyme. Annu Rev Biophys Struct 34 (2005) 415-440
-
(2005)
Annu Rev Biophys Struct
, vol.34
, pp. 415-440
-
-
Blount, K.B.1
Uhlenbeck, O.C.2
-
20
-
-
0043009734
-
Sequence elements outside the hammerhead ribozyme catalytic core enable intracellular activity
-
Khvorova A., Lescoute A., Westhof E., and Jayasena S.D. Sequence elements outside the hammerhead ribozyme catalytic core enable intracellular activity. Nat Struct Biol 10 (2003) 708-712
-
(2003)
Nat Struct Biol
, vol.10
, pp. 708-712
-
-
Khvorova, A.1
Lescoute, A.2
Westhof, E.3
Jayasena, S.D.4
-
21
-
-
0142105383
-
Peripheral regions of natural hammerhead ribozymes greatly increase their self-cleavage activity
-
De la Pena M., Gago S., and Flores R. Peripheral regions of natural hammerhead ribozymes greatly increase their self-cleavage activity. EMBO J 22 (2003) 5561-5570
-
(2003)
EMBO J
, vol.22
, pp. 5561-5570
-
-
De la Pena, M.1
Gago, S.2
Flores, R.3
-
22
-
-
33746228126
-
Tertiary contacts distant from the active site prime a ribozyme for catalysis
-
Martick M., and Scott W.G. Tertiary contacts distant from the active site prime a ribozyme for catalysis. Cell 126 (2006) 309-319
-
(2006)
Cell
, vol.126
, pp. 309-319
-
-
Martick, M.1
Scott, W.G.2
-
24
-
-
41649101909
-
Hammerhead redux: does the new structure fit the old biochemical data?
-
An analysis/review of a variety of minimal hammerhead ribozymes that demonstrate an agreement from biochemical studies to the updated structure of the extended hammerhead.
-
Nelson J.A., and Uhlenbeck O.C. Hammerhead redux: does the new structure fit the old biochemical data?. RNA 14 (2008) 605-615. An analysis/review of a variety of minimal hammerhead ribozymes that demonstrate an agreement from biochemical studies to the updated structure of the extended hammerhead.
-
(2008)
RNA
, vol.14
, pp. 605-615
-
-
Nelson, J.A.1
Uhlenbeck, O.C.2
-
25
-
-
41949138497
-
Solvent structure and hammerhead ribozyme
-
This article presents mechanistic hypotheses for the roles of the nucleobases in the active site.
-
Martick M., Lee T.S., York D.M., and Scott W.G. Solvent structure and hammerhead ribozyme. Chem Biol 15 (2008) 332-342. This article presents mechanistic hypotheses for the roles of the nucleobases in the active site.
-
(2008)
Chem Biol
, vol.15
, pp. 332-342
-
-
Martick, M.1
Lee, T.S.2
York, D.M.3
Scott, W.G.4
-
26
-
-
19644391548
-
Model for general acid-base catalysis by the hammerhead ribozyme: pH-activity relationships of G8 and G12 variants at the putative active site
-
Han J., and Burke J.M. Model for general acid-base catalysis by the hammerhead ribozyme: pH-activity relationships of G8 and G12 variants at the putative active site. Biochemistry 44 (2005) 7864-7870
-
(2005)
Biochemistry
, vol.44
, pp. 7864-7870
-
-
Han, J.1
Burke, J.M.2
-
27
-
-
38049029204
-
Minimal and extended hammerheads utilize a similar dynamic reaction mechanism for catalysis
-
Nucleotide residues not previously known to have an interaction in the active site of the minimal hammerhead, are the main subject of this study along with the demonstration that the minimal hammerhead is still a relevant model.
-
Nelson J.A., and Uhlenbeck O.C. Minimal and extended hammerheads utilize a similar dynamic reaction mechanism for catalysis. RNA 14 (2008) 43-54. Nucleotide residues not previously known to have an interaction in the active site of the minimal hammerhead, are the main subject of this study along with the demonstration that the minimal hammerhead is still a relevant model.
-
(2008)
RNA
, vol.14
, pp. 43-54
-
-
Nelson, J.A.1
Uhlenbeck, O.C.2
-
28
-
-
56449119364
-
Probing general base catalysis in the hammerhead ribozyme
-
A paper that presents evidence for G12 serving as a general base.
-
Thomas J.M., and Perrin D.M. Probing general base catalysis in the hammerhead ribozyme. J Am Chem Soc 130 (2008) 15467-15475. A paper that presents evidence for G12 serving as a general base.
-
(2008)
J Am Chem Soc
, vol.130
, pp. 15467-15475
-
-
Thomas, J.M.1
Perrin, D.M.2
-
29
-
-
47649130326
-
The different role of high-affinity and low-affinity metal ions in cleavage by a tertiary stabilized cis hammerhead ribozyme from tobacco ringspot virus
-
Kisseleva N., Khvorova A., Westhof E., Schiemann O., and Wolfson A.D. The different role of high-affinity and low-affinity metal ions in cleavage by a tertiary stabilized cis hammerhead ribozyme from tobacco ringspot virus. Oligonucleotides 18 (2008) 101-110
-
(2008)
Oligonucleotides
, vol.18
, pp. 101-110
-
-
Kisseleva, N.1
Khvorova, A.2
Westhof, E.3
Schiemann, O.4
Wolfson, A.D.5
-
30
-
-
0035001461
-
Comparison of the hammerhead cleavage reactions stimulated by monovalent and divalent cations
-
O'Rear J.L., Wang S., and Feig A.L. Comparison of the hammerhead cleavage reactions stimulated by monovalent and divalent cations. RNA 7 (2001) 537-545
-
(2001)
RNA
, vol.7
, pp. 537-545
-
-
O'Rear, J.L.1
Wang, S.2
Feig, A.L.3
-
31
-
-
52949104434
-
Metal ion specificities for folding and cleavage activity in the Schistoma hammerhead ribozyme
-
Boots J.L., Canny M.D., and Azimi E. Metal ion specificities for folding and cleavage activity in the Schistoma hammerhead ribozyme. RNA 14 (2008) 2212-2222
-
(2008)
RNA
, vol.14
, pp. 2212-2222
-
-
Boots, J.L.1
Canny, M.D.2
Azimi, E.3
-
33
-
-
61749098364
-
Probing general acid catalysis in the hammerhead ribozyme
-
This paper provides evidence for the specific role of divalent metal ions as general acids.
-
Thomas J.M., and Perrin D.M. Probing general acid catalysis in the hammerhead ribozyme. J Am Chem Soc 131 (2009) 1135-1143. This paper provides evidence for the specific role of divalent metal ions as general acids.
-
(2009)
J Am Chem Soc
, vol.131
, pp. 1135-1143
-
-
Thomas, J.M.1
Perrin, D.M.2
-
34
-
-
70549095462
-
Is the spliceosome a ribozyme?
-
Lilley D.M., and Eckstein F. (Eds), RSC Publishing
-
Sashital D.G., and Butcher S. Is the spliceosome a ribozyme?. In: Lilley D.M., and Eckstein F. (Eds). Ribozymes and RNA Catalysis (2008), RSC Publishing 253-269
-
(2008)
Ribozymes and RNA Catalysis
, pp. 253-269
-
-
Sashital, D.G.1
Butcher, S.2
-
35
-
-
55549121900
-
Structural elucidation of a PRP8 core domain from the heart of the spliceosome
-
Ritchie D.B., Schellenberg M.J., Gesner E.M., Raithatha S.A., Stuart D.T., and MacMillan A.M. Structural elucidation of a PRP8 core domain from the heart of the spliceosome. Nat Struct Mol Biol 15 (2008) 1199-1205
-
(2008)
Nat Struct Mol Biol
, vol.15
, pp. 1199-1205
-
-
Ritchie, D.B.1
Schellenberg, M.J.2
Gesner, E.M.3
Raithatha, S.A.4
Stuart, D.T.5
MacMillan, A.M.6
-
36
-
-
55549143970
-
Structure and function of an Rnase H domain at the heart of the spliceosome
-
Pena V., Rozov A., Fabrizio P., Luhrmann R., and Wahl M.C. Structure and function of an Rnase H domain at the heart of the spliceosome. EMBO J 27 (2008) 2929-2940
-
(2008)
EMBO J
, vol.27
, pp. 2929-2940
-
-
Pena, V.1
Rozov, A.2
Fabrizio, P.3
Luhrmann, R.4
Wahl, M.C.5
-
37
-
-
60349104299
-
The spliceosome: design principles of a dynamic RNP machine
-
The most up-to-date review covering both the protein and RNA components of the spliceosome in structural and functional roles.
-
Wahl M.C., Will C.L., and Luhrmann R. The spliceosome: design principles of a dynamic RNP machine. Cell 136 (2009) 701-718. The most up-to-date review covering both the protein and RNA components of the spliceosome in structural and functional roles.
-
(2009)
Cell
, vol.136
, pp. 701-718
-
-
Wahl, M.C.1
Will, C.L.2
Luhrmann, R.3
-
38
-
-
62949146385
-
Splicing of mRNA precursors: the role of RNAs and proteins in catalysis
-
A recent review focusing on the catalysis aspect of the spliceosome.
-
Wachtel C., and Manely J.L. Splicing of mRNA precursors: the role of RNAs and proteins in catalysis. Mol Biosyst 5 (2009) 311-316. A recent review focusing on the catalysis aspect of the spliceosome.
-
(2009)
Mol Biosyst
, vol.5
, pp. 311-316
-
-
Wachtel, C.1
Manely, J.L.2
-
39
-
-
0002340095
-
RNA-RNA interaction in nuclear pre-mRNA splicing
-
Simon R.W., and Grunberg-Manago M. (Eds), Cold Spring Harbor Laboratory Press
-
Nilsen T.W. RNA-RNA interaction in nuclear pre-mRNA splicing. In: Simon R.W., and Grunberg-Manago M. (Eds). RNA Structure and Function (1998), Cold Spring Harbor Laboratory Press 279-307
-
(1998)
RNA Structure and Function
, pp. 279-307
-
-
Nilsen, T.W.1
-
40
-
-
0035252410
-
Alternative splicing: increasing diversity in the proteomic world
-
Gravely B.R. Alternative splicing: increasing diversity in the proteomic world. Trends Genet 17 (2001) 100-107
-
(2001)
Trends Genet
, vol.17
, pp. 100-107
-
-
Gravely, B.R.1
-
41
-
-
0345169036
-
Splicing double: insight from the second spliceosome
-
Patel A.A., and Steitz J.A. Splicing double: insight from the second spliceosome. Nat Rev 4 (2003) 960-970
-
(2003)
Nat Rev
, vol.4
, pp. 960-970
-
-
Patel, A.A.1
Steitz, J.A.2
-
42
-
-
33645213731
-
Spliceosome structure and function
-
Gesteland R., Cech T.R., and Atkins J.F. (Eds), Cold Spring Harbor Laboratory Press
-
Will C.L., and Luhrmann R. Spliceosome structure and function. In: Gesteland R., Cech T.R., and Atkins J.F. (Eds). The RNA World (2006), Cold Spring Harbor Laboratory Press 369-400
-
(2006)
The RNA World
, pp. 369-400
-
-
Will, C.L.1
Luhrmann, R.2
-
43
-
-
34250660469
-
The spliceosome: a ribozyme at heart?
-
Valadkhan S. The spliceosome: a ribozyme at heart?. Biol Chem 388 (2007) 693-697
-
(2007)
Biol Chem
, vol.388
, pp. 693-697
-
-
Valadkhan, S.1
-
44
-
-
44949246374
-
"Nought may endure but mutability": spliceosome dynamics and the regulation of splicing
-
Smith D.J., Query C.C., and Konarska M.M. "Nought may endure but mutability": spliceosome dynamics and the regulation of splicing. Mol Cell 30 (2008) 657-666
-
(2008)
Mol Cell
, vol.30
, pp. 657-666
-
-
Smith, D.J.1
Query, C.C.2
Konarska, M.M.3
-
45
-
-
0027739853
-
The U5 and U6 small nuclear RNAs as active site components of the spliceosome
-
Sontheimer E.J., and Steiz J.A. The U5 and U6 small nuclear RNAs as active site components of the spliceosome. Science 262 (1993) 1989-1996
-
(1993)
Science
, vol.262
, pp. 1989-1996
-
-
Sontheimer, E.J.1
Steiz, J.A.2
-
46
-
-
0027739852
-
Mutations in U6 snRNA that alter splice site specificity: implications for the active site
-
Lesser C.F., and Guthrie C. Mutations in U6 snRNA that alter splice site specificity: implications for the active site. Science 262 (1993) 1982-1988
-
(1993)
Science
, vol.262
, pp. 1982-1988
-
-
Lesser, C.F.1
Guthrie, C.2
-
47
-
-
0027923620
-
Role of U6 snRNA in 5′ splice site selection
-
Kandels-Lewis S., and Seraphin B. Role of U6 snRNA in 5′ splice site selection. Science 262 (1993) 2035-2039
-
(1993)
Science
, vol.262
, pp. 2035-2039
-
-
Kandels-Lewis, S.1
Seraphin, B.2
-
48
-
-
0028917214
-
A novel U2-U6 snRNA structure is necessary for mammalian mRNA splicing
-
Sun J.S., and Manley J.L. A novel U2-U6 snRNA structure is necessary for mammalian mRNA splicing. Genes Dev 9 (1995) 843-854
-
(1995)
Genes Dev
, vol.9
, pp. 843-854
-
-
Sun, J.S.1
Manley, J.L.2
-
49
-
-
0034649666
-
Metal-ion coordination by U6 small nuclear RNA contributes to catalysis in the spliceosome
-
Yean S.L., Wuenschell G., Termini J., and Lin R.J. Metal-ion coordination by U6 small nuclear RNA contributes to catalysis in the spliceosome. Nature 408 (2000) 881-884
-
(2000)
Nature
, vol.408
, pp. 881-884
-
-
Yean, S.L.1
Wuenschell, G.2
Termini, J.3
Lin, R.J.4
-
50
-
-
0033792637
-
The question remains: is the spliceosome a ribozyme?
-
Collins C.A., and Guthries C. The question remains: is the spliceosome a ribozyme?. Nat Struct Biol 7 (2000) 850-854
-
(2000)
Nat Struct Biol
, vol.7
, pp. 850-854
-
-
Collins, C.A.1
Guthries, C.2
-
51
-
-
0036948420
-
Allosteric cascade of spliceosome activation
-
Brow D.A. Allosteric cascade of spliceosome activation. Annu Rev Genet 36 (2002) 333-360
-
(2002)
Annu Rev Genet
, vol.36
, pp. 333-360
-
-
Brow, D.A.1
-
52
-
-
21044444993
-
Towards understanding the catalytic core structure of the spliceosome
-
Butcher S.E., and Brow D. Towards understanding the catalytic core structure of the spliceosome. Biochem Soc Trans 33 (2005) 447-449
-
(2005)
Biochem Soc Trans
, vol.33
, pp. 447-449
-
-
Butcher, S.E.1
Brow, D.2
-
53
-
-
0022131865
-
On the origin of RNA splicing and Introns
-
Sharp P.A. On the origin of RNA splicing and Introns. Cell 42 (1985) 397-400
-
(1985)
Cell
, vol.42
, pp. 397-400
-
-
Sharp, P.A.1
-
54
-
-
0022552726
-
The generality of self-splicing RNA: relationship to nuclear mRNA splicing
-
Cech T.R. The generality of self-splicing RNA: relationship to nuclear mRNA splicing. Cell 44 (1986) 207-210
-
(1986)
Cell
, vol.44
, pp. 207-210
-
-
Cech, T.R.1
-
55
-
-
0033965261
-
Metal ion catalysis during the exon-ligation step of nuclear pre-mRNA splicing: extending the parallels between the spliceosome and group II introns
-
Gordon P.M., Sontheimer E.J., and Piccirilli J.A. Metal ion catalysis during the exon-ligation step of nuclear pre-mRNA splicing: extending the parallels between the spliceosome and group II introns. RNA 6 (2000) 199-205
-
(2000)
RNA
, vol.6
, pp. 199-205
-
-
Gordon, P.M.1
Sontheimer, E.J.2
Piccirilli, J.A.3
-
56
-
-
48649104354
-
A glimpse into the active site of a group II intron and maybe the spliceosome, too
-
Interesting paper that reviews the recent publication of the group II intron crystal structure and highlights the similarities with the U6 snRNA of the spliceosome.
-
Dayie K.T., and Padgett R.A. A glimpse into the active site of a group II intron and maybe the spliceosome, too. RNA 14 (2008) 1697-1703. Interesting paper that reviews the recent publication of the group II intron crystal structure and highlights the similarities with the U6 snRNA of the spliceosome.
-
(2008)
RNA
, vol.14
, pp. 1697-1703
-
-
Dayie, K.T.1
Padgett, R.A.2
-
57
-
-
0032079365
-
Selection in vitro of novel ribozymes from a partially randomized U2 and U6 snRNA library
-
Tushcel T., Sharp P.A., and Bartel D.A. Selection in vitro of novel ribozymes from a partially randomized U2 and U6 snRNA library. EMBO J 17 (1998) 2637-2650
-
(1998)
EMBO J
, vol.17
, pp. 2637-2650
-
-
Tushcel, T.1
Sharp, P.A.2
Bartel, D.A.3
-
58
-
-
0035040190
-
A ribozyme selected from variants of U6 snRNA promotes 2′,5′-branch formation
-
Tushcel T., Sharp P.A., and Bartel D.A. A ribozyme selected from variants of U6 snRNA promotes 2′,5′-branch formation. RNA 7 (2001) 29-43
-
(2001)
RNA
, vol.7
, pp. 29-43
-
-
Tushcel, T.1
Sharp, P.A.2
Bartel, D.A.3
-
59
-
-
0035909314
-
Splicing-related catalysis by protein-free snRNAs
-
Valadkhan S., and Manley J.L. Splicing-related catalysis by protein-free snRNAs. Nature 413 (2001) 701-707
-
(2001)
Nature
, vol.413
, pp. 701-707
-
-
Valadkhan, S.1
Manley, J.L.2
-
60
-
-
0038719932
-
Characterization of the catalytic activity of U2 and U6 snRNAs
-
Valadkhan S., and Manley J.L. Characterization of the catalytic activity of U2 and U6 snRNAs. RNA 9 (2003) 892-904
-
(2003)
RNA
, vol.9
, pp. 892-904
-
-
Valadkhan, S.1
Manley, J.L.2
-
61
-
-
36248936068
-
Protein-free spliceosomal snRNAs catalyzes a reaction that resembles the first step of splicing
-
Valadkhan S., Mohammadi A., and Wachtel C. Protein-free spliceosomal snRNAs catalyzes a reaction that resembles the first step of splicing. RNA 13 (2007) 2300-2311
-
(2007)
RNA
, vol.13
, pp. 2300-2311
-
-
Valadkhan, S.1
Mohammadi, A.2
Wachtel, C.3
-
62
-
-
58149086405
-
Identification and characterization of short 2′-3′ bond forming ribozyme
-
In attempting to use a modified version of the U2-U6 minimal version, a different ribozyme within the model itself is discovered.
-
Smith D.J., and Konarska M.M. Identification and characterization of short 2′-3′ bond forming ribozyme. RNA 15 (2009) 8-13. In attempting to use a modified version of the U2-U6 minimal version, a different ribozyme within the model itself is discovered.
-
(2009)
RNA
, vol.15
, pp. 8-13
-
-
Smith, D.J.1
Konarska, M.M.2
-
63
-
-
58149088299
-
A critical assessment of the utility of protein-free splicing systems
-
Smith D.J., and Konarska M.M. A critical assessment of the utility of protein-free splicing systems. RNA 15 (2009) 1-3
-
(2009)
RNA
, vol.15
, pp. 1-3
-
-
Smith, D.J.1
Konarska, M.M.2
-
64
-
-
58149099850
-
The use of simple model systems to study spliceosomal catalysis
-
Valadkhan S., and Manley J.L. The use of simple model systems to study spliceosomal catalysis. RNA 15 (2009) 4-7
-
(2009)
RNA
, vol.15
, pp. 4-7
-
-
Valadkhan, S.1
Manley, J.L.2
-
66
-
-
60149103676
-
The centrality of RNA
-
Sharp P.A. The centrality of RNA. Cell 136 (2009) 577-580
-
(2009)
Cell
, vol.136
, pp. 577-580
-
-
Sharp, P.A.1
-
67
-
-
66149131755
-
Systems chemistry on early Earth
-
Szostak J.W. Systems chemistry on early Earth. Nature 459 (2009) 171-172
-
(2009)
Nature
, vol.459
, pp. 171-172
-
-
Szostak, J.W.1
-
68
-
-
66149108671
-
Synthesis of activated pyrimidine ribonucleotides in prebiotically plausible conditions
-
Challenges in the prebiotic syntheses of RNA nucleotides are shown to be overcome by some clever synthetic chemistry.
-
Powner M.W., Gerland B., and Sutherland J.D. Synthesis of activated pyrimidine ribonucleotides in prebiotically plausible conditions. Nature 459 (2009) 230-242. Challenges in the prebiotic syntheses of RNA nucleotides are shown to be overcome by some clever synthetic chemistry.
-
(2009)
Nature
, vol.459
, pp. 230-242
-
-
Powner, M.W.1
Gerland, B.2
Sutherland, J.D.3
-
70
-
-
0014378880
-
The origin of the genetic code
-
Crick F.C. The origin of the genetic code. J Mol Biol 38 (1968) 367-379
-
(1968)
J Mol Biol
, vol.38
, pp. 367-379
-
-
Crick, F.C.1
-
71
-
-
0014369024
-
Evolution of the genetic apparatus
-
Orgel L.E. Evolution of the genetic apparatus. J Mol Biol 38 (1968) 381-393
-
(1968)
J Mol Biol
, vol.38
, pp. 381-393
-
-
Orgel, L.E.1
-
72
-
-
36849148382
-
The RNA world
-
Gilbert W. The RNA world. Nature 319 (1986) 618
-
(1986)
Nature
, vol.319
, pp. 618
-
-
Gilbert, W.1
-
73
-
-
62449245467
-
The evolution of ribozyme chemistry
-
The elucidation of ribozyme mechanisms is essential for understanding the RNA world hypothesis.
-
Wilson T.J., and Lilley D.M. The evolution of ribozyme chemistry. Science 323 (2009) 1436-1438. The elucidation of ribozyme mechanisms is essential for understanding the RNA world hypothesis.
-
(2009)
Science
, vol.323
, pp. 1436-1438
-
-
Wilson, T.J.1
Lilley, D.M.2
-
74
-
-
60849093158
-
Group II introns: catalysts for splicing, genomic change and evolution
-
Lilley D.M., and Eckstein F. (Eds), RSC Publishing
-
Pyle A.M. Group II introns: catalysts for splicing, genomic change and evolution. In: Lilley D.M., and Eckstein F. (Eds). Ribozymes and RNA Catalysis (2008), RSC Publishing 201-228
-
(2008)
Ribozymes and RNA Catalysis
, pp. 201-228
-
-
Pyle, A.M.1
-
75
-
-
60149101421
-
Crawling out of the RNA world
-
In considering the evolution of RNPs, they may have used proteins all along, even in the RNA world.
-
Cech T.R. Crawling out of the RNA world. Cell 136 (2009) 599-602. In considering the evolution of RNPs, they may have used proteins all along, even in the RNA world.
-
(2009)
Cell
, vol.136
, pp. 599-602
-
-
Cech, T.R.1
-
77
-
-
34247862281
-
Toward ribosomal RNA catalytic activity in the absence of protein
-
Anderson R.M., Kwoon M., and Strobel S.A. Toward ribosomal RNA catalytic activity in the absence of protein. J Mol Evol 64 (2007) 472-483
-
(2007)
J Mol Evol
, vol.64
, pp. 472-483
-
-
Anderson, R.M.1
Kwoon, M.2
Strobel, S.A.3
-
78
-
-
60549112849
-
A hierarchical model for evolution of 23S ribosomal RNA
-
Bokov K., and Steinberg S. A hierarchical model for evolution of 23S ribosomal RNA. Nature 457 (2009) 977-980
-
(2009)
Nature
, vol.457
, pp. 977-980
-
-
Bokov, K.1
Steinberg, S.2
-
79
-
-
68949156176
-
The dimeric proto-ribosome: structural details and possible implications on the origin of life
-
Agmon I. The dimeric proto-ribosome: structural details and possible implications on the origin of life. Int J Mol Sci 10 (2009) 2921-2934
-
(2009)
Int J Mol Sci
, vol.10
, pp. 2921-2934
-
-
Agmon, I.1
-
80
-
-
70549094724
-
Identification of the prebiotic translation apparatus within the contemporary ribosome
-
hdl:10101/npre.2009.2921.1: posted 4 Mar 2009
-
Agmon I., Davidovich C., Bashan A., and Yonath A. Identification of the prebiotic translation apparatus within the contemporary ribosome. Nat Precedings (2009) hdl:10101/npre.2009.2921.1: posted 4 Mar 2009
-
(2009)
Nat Precedings
-
-
Agmon, I.1
Davidovich, C.2
Bashan, A.3
Yonath, A.4
-
81
-
-
34247114031
-
Evolution of ribosomes and translation from an RNA world
-
Gesteland R., Cech T.R., and Atkins J.F. (Eds), Cold Spring Harbor Laboratory Press
-
Noller H.F. Evolution of ribosomes and translation from an RNA world. In: Gesteland R., Cech T.R., and Atkins J.F. (Eds). The RNA World (2006), Cold Spring Harbor Laboratory Press 287-307
-
(2006)
The RNA World
, pp. 287-307
-
-
Noller, H.F.1
-
82
-
-
0034903851
-
Translation: in retrospect and prospect
-
Woese C. Translation: in retrospect and prospect. RNA 7 (2001) 1055-1067
-
(2001)
RNA
, vol.7
, pp. 1055-1067
-
-
Woese, C.1
-
83
-
-
67649354912
-
Evidence that U2/U6 helix I promotes both catalytic steps of pre-mRNA splicing and rearranges in between these steps
-
Mefford M.A., and Staley J.P. Evidence that U2/U6 helix I promotes both catalytic steps of pre-mRNA splicing and rearranges in between these steps. RNA 15 (2009) 1386-1397
-
(2009)
RNA
, vol.15
, pp. 1386-1397
-
-
Mefford, M.A.1
Staley, J.P.2
-
84
-
-
50649108969
-
The production line
-
Petherick A. The production line. Nature 454 (2008) 1042-1045
-
(2008)
Nature
, vol.454
, pp. 1042-1045
-
-
Petherick, A.1
|