Probing general base catalysis in the hammerhead ribozyme

Journal of the American Chemical Society

Volumn 130, Issue 46, 2008, Pages 15467-15475

  Thomas, Jason M ^a   Perrin, David M ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLATION; CATALYSIS; CHEMICAL REACTIONS; FUNCTIONAL GROUPS; HYDROCARBONS; NUCLEIC ACIDS; QUANTUM CHEMISTRY; RNA;

ACTIVE SITE STRUCTURES; BASE CATALYSES; CATALYTIC MECHANISMS; CLEAVAGE REACTIONS; COMPUTATIONAL STUDIES; FOOTPRINTING ANALYSES; GENERAL BASE CATALYSES; HYDROXYL GROUPS; RIBOZYME; SUBSTRATE ANALOGUES;

MEATS;

2' BROMOACETAMIDE; BASE; MAGNESIUM; RIBOZYME; UNCLASSIFIED DRUG;

AFFINITY LABELING; ALKYLATION; ARTICLE; CATALYSIS; NONHUMAN; PH; PKA; RNA CLEAVAGE; RNA CONFORMATION; RNA STRUCTURE; SCHISTOSOMA MANSONI;

ANIMALS; BASE SEQUENCE; BIOCATALYSIS; HYDROGEN-ION CONCENTRATION; MODELS, MOLECULAR; MOLECULAR PROBES; MOLECULAR SEQUENCE DATA; MUTATION; NUCLEIC ACID CONFORMATION; PROTEIN STRUCTURE, TERTIARY; RNA, CATALYTIC; SCHISTOSOMA MANSONI;

EID: 56449119364     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja804496z     Document Type: Article

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