Sequence elements outside the hammerhead ribozyme catalytic core enable intracellular activity

Nature Structural Biology

Volumn 10, Issue 9, 2003, Pages 708-712

  Khvorova, Anastasia ^a,b   Lescoute, Aurélie ^c   Westhof, Eric ^c   Jayasena, Sumedha D ^a  

^a AMGEN INC   (United States)

^b Dharmacon Inc   (United States)

^c INST DE BIOL MOLEC ET CELLULAIRE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

HAMMERHEAD RIBOZYME; RIBOZYME; RNA; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME STRUCTURE; GENE EXPRESSION; GENETIC TRANSCRIPTION; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; REPORTER GENE; RNA CLEAVAGE;

AMINO ACID MOTIFS; BASE SEQUENCE; CATALYSIS; DOSE-RESPONSE RELATIONSHIP, DRUG; GENES, REPORTER; GENETIC VECTORS; KINETICS; MAGNESIUM; MOLECULAR SEQUENCE DATA; MUTATION; NUCLEIC ACID CONFORMATION; PLASMIDS; PROTEIN BINDING; PROTEIN CONFORMATION; RNA; RNA, CATALYTIC; SEQUENCE HOMOLOGY, NUCLEIC ACID; TIME FACTORS;

EID: 0043009734     PISSN: 10728368     EISSN: None     Source Type: Journal    
DOI: 10.1038/nsb959     Document Type: Article

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