Identification of critical residues within the conserved and specificity patches of nerve growth factor leading to survival or differentiation

Journal of Biological Chemistry

Volumn 284, Issue 48, 2009, Pages 33600-33613

  Mahapatra, Sidharth ^a   Mehta, Hrishikesh ^a   Woo, Sang B ^a   Neet, Kenneth E ^a  

^a ROSALIND FRANKLIN UNIVERSITY OF MEDICINE AND SCIENCE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER DISEASE; CELL SURFACES; CELL SURVIVAL; DOSE-RESPONSE CURVES; LIGAND-RECEPTOR; MAPK SIGNALING; MUTEINS; NEGATIVE CONTROL; NERVE GROWTH FACTOR; NEURITES; NEURITOGENESIS; PC12 CELLS; POINT MUTAGENESIS; POINT MUTATIONS; SURFACE PLASMONS; WILD TYPES;

BIOACTIVITY; CELL CULTURE; CELL MEMBRANES; PEPTIDES; SIGNALING; SURFACE PLASMON RESONANCE;

PLANTS (BOTANY);

CYCLINE; NEUROTROPHIN RECEPTOR P75; PROTEIN TYROSINE KINASE A; RECOMBINANT NERVE GROWTH FACTOR;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CELL SPECIFICITY; CELL SURVIVAL; CONTROLLED STUDY; FIBROBLAST; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SITE DIRECTED MUTAGENESIS; WILD TYPE;

AMINO ACID SEQUENCE; AMINO ACIDS; ANIMALS; BINDING SITES; CELL DIFFERENTIATION; CELL LINE; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FIBROBLASTS; MAP KINASE SIGNALING SYSTEM; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; MUTANT PROTEINS; NERVE GROWTH FACTOR; NEURITES; PC12 CELLS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RATS; RECEPTOR, NERVE GROWTH FACTOR; RECEPTOR, TRKA; RECOMBINANT PROTEINS; SPODOPTERA; SURFACE PLASMON RESONANCE;

EID: 70450250025     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.058420     Document Type: Article

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