Ligand regulates epidermal growth factor receptor kinase specificity: Activation increases preference for Gab1 and Shc versus autophosphorylation sites

Journal of Biological Chemistry

Volumn 279, Issue 37, 2004, Pages 38143-38150

  Fan, Ying Xin ^a   Wong, Lily ^a   Deb, Tushar B ^a,b   Johnson, Gibbes R ^a  

^a CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^b GEORGETOWN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; BIOCHEMICAL ENGINEERING; CELL MEMBRANES; GROWTH KINETICS;

AUTOPHOSPHORYLATION; EPIDERMAL GROWTH FACTOR (EGF); LIGANDS; PEPTIDES;

ENZYME KINETICS;

COMPLEMENTARY DNA; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE; GAB1 PROTEIN; GLUTATHIONE TRANSFERASE; HYBRID PROTEIN; PROTEIN; PROTEIN SHC; PROTEIN TYROSINE KINASE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; AUTOPHOSPHORYLATION; BINDING AFFINITY; CELL TRANSFORMATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; ENZYME PURIFICATION; ENZYME SPECIFICITY; NONHUMAN; PEPTIDE SYNTHESIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADAPTOR PROTEINS, VESICULAR TRANSPORT; ANIMALS; BINDING SITES; BLOTTING, WESTERN; CATALYTIC DOMAIN; CELL LINE; COS CELLS; DNA, COMPLEMENTARY; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; EPIDERMAL GROWTH FACTOR; EPITOPES; GLUTATHIONE TRANSFERASE; KINETICS; LIGANDS; MICE; PEPTIDES; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEIN-TYROSINE KINASES; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECOMBINANT FUSION PROTEINS; SUBSTRATE SPECIFICITY; TIME FACTORS; TYROSINE;

ANIMALIA; FELIS CATUS;

EID: 4644337782     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M405760200     Document Type: Article

References (54)

1. Ullrich, A., and Schlessinger, J. (1990) Cell 61, 203-212
2. Schlessinger, J. (2000) Cell 103, 211-225
3. Holgado-Madruga, M., Emlet, D. R., Moscatello, D. K., Godwin, A. K., and Wong, A. J. (1996) Nature 379, 560-564
4. Pelicci, G., Lanfrancone, L., Grignani, F., McGlade, J., Cavallo, F., Forni, G., Nicoletti, I., Pawson, T., and Pelicci, P. G. (1992) Cell 70, 93-104
5. Carpenter, G. (1992) FASEB J. 6, 3283-3289
6. Kim, J., Sim, S., Kim, U., Nishibe, S., Wahl, M., Carpenter, G., and Rhee, S. (1990) J. Biol. Chem. 265, 3940-3943
7. Jorissen, R. N., Walker, F., Pouliot, N., Garrett, T. P., Ward, C. W., and Burgess, A. W. (2003) Exp. Cell Res. 284, 31-53
8. Kim, E. S., Khuri, F. R., and Herbst, R. S. (2001) Curr. Opin. Oncol. 13, 506-513
9. Yarden, Y. (2001) Eur. J. Cancer 37, Suppl. 4, 3-8
10. Ellis, L., Clauser, E., Morgan, D. O., Edery, M., Roth, R. A., and Rutter, W. J. (1986) Cell 45, 721-732
11. Mohammadi, M., Dikic, I., Sorokin, A., Burgess, W. H., Jaye, M., and Schlessinger, J. (1996) Mol. Cell. Biol. 16, 977-989
12. Fantl, W. J., Escobedo, J. A., and Williams, L. T. (1989) Mol. Cell. Biol. 9, 4473-4478
13. Hubbard, S. R., Wei, L., Ellis, L., and Hendrickson, W. A. (1994) Nature 372, 746-754
14. Mohammadi, M., Schlessinger, J., and Hubbard, S. R. (1996) Cell 86, 577-587
15. Gotoh, N., Tojo, A., Hino, M., Yazaki, Y., and Shibuya, M. (1992) Biochem. Biophys. Res. Commun. 188, 768-774
16. Stamos, J., Sliwkowski, M. X., and Eigenbrot, C. (2002) J. Biol. Chem. 277, 46265-46272
17. Hubbard, S. R. (1997) EMBO J. 16, 5572-5581
18. Knighton, D. R., Zheng, J. H., Ten Eyck, L. F., Ashford, V. A., Xuong, N. H., Taylor, S. S., and Sowadski, J. M. (1991) Science 253, 407-414
19. Songyang, Z., Carraway, K. L., III, Eck, M. J., Harrison, S. C., Feldman, R. A., Mohammadi, M., Schlessinger, J., Hubbard, S. R., Smith, D. P., Eng, C., Lorenzo, M. J., Ponder, B. A. J., Mayer, B. J., and Cantley, L. C. (1995) Nature 373, 536-539
20. Kemp, B. E., Parker, M. W., Hu, S., Tiganis, T., and House, C. (1994) Trends Biochem. Sci. 19, 440-444
21. Casnellie, J. E., Harrison, M. L., Pike, L. J., Hellstrom, K. E., and Krebs, E. G. (1982) Proc. Natl. Acad. Sci. U. S. A. 79, 282-286
22. Patschinsky, T., Hunter, T., Esch, F. S., Cooper, J. A., and Sefton, B. M. (1982) Proc. Natl. Acad. Sci. U. S. A. 79, 973-977
23. Hunter, T., and Cooper, J. A. (1985) Annu. Rev. Biochem. 54, 897-930
24. Downward, J., Waterfield, M. D., and Parker, P. J. (1985) J. Biol. Chem. 260, 14538-14546
25. Honegger, A., Dull, T. J., Szapary, D., Komoriya, A., Kris, R., Ullrich, A., and Schlessinger, J. (1988) EMBO J. 7, 3053-3060
26. Takahashi-Tezuka, M., Yoshida, Y., Fukada, T., Ohtani, T., Yamanaka, Y., Nishida, K., Nakajima, K., Hibi, M., and Hirano, T. (1998) Mol. Cell. Biol. 18, 4109-4117
27. Cunnick, J. M., Mei, L., Doupnik, C. A., and Wu, J. (2001) J. Biol. Chem. 276, 24380-24387
28. Greenberger, J. S., Sakakeeny, M. A., Humphries, R. K., Eaves, C. J., and Eckner, R. J. (1983) Proc. Natl. Acad. Sci. U. S. A. 80, 2931-2935
29. Luthman, H., and Magnusson, G. (1983) Nucleic Acids Res. 11, 1295-1308
30. Deb, T. B., Su, L., Wong, L., Bonvini, E., Wells, A., David, M., and Johnson, G. R. (2001) J. Biol. Chem. 276, 15554-15560
31. Alimandi, M., Wang, L. M., Bottaro, D., Lee, C. C., Kuo, A., Frankel, M., Fedi, P., Tang, C., Lippman, M., and Pierce, J. H. (1997) EMBO J. 16, 5608-5617
32. Downward, J., Parker, P., and Waterfield, M. D. (1984) Nature 311, 483-485
33. Margolis, B. L., Lax, I., Kris, R., Dombalagian, M., Honegger, A. M., Howk, R., Givol, D., Ullrich, A., and Schlessinger, J. (1989) J. Biol. Chem. 264, 10667-10671
34. Hsuan, J. J., Totty, N., and Waterfield, M. D. (1989) Biochem. J. 262, 659-663
35. Walton, G. M., Chen, W. S., Rosenfeld, M. G., and Gill, G. N. (1990) J. Biol. Chem. 265, 1750-1754
36. Guo, L., Kozlosky, C. J., Ericsson, L. H., Daniel, T. O., Cerretti, D. P., and Johnson, R. S. (2003) J. Am. Soc. Mass Spectrom. 14, 1022-1031
37. Gotoh, N., Toyoda, M., and Shibuya, M. (1997) Mol. Cell. Biol. 17, 1824-1831
38. Lehr, S., Kotzka, J., Herkner, A., Klein, E., Siethoff, C., Knebel, B., Noelle, V., Bruning, J. C., Klein, H. W., Meyer, H. E., Krone, W., and Muller-Wieland, D. (1999) Biochemistry 38, 151-159
39. Rotin, D., Honegger, A., Margolis, B., Ullrich, A., and Schlessinger, J. (1992) J. Biol. Chem. 267, 9678-9683
40. Ablooglu, A. J., and Kohanski, R. A. (2001) Biochemistry 40, 504-513
41. Knighton, D. R., Zheng, J. H., Ten Eyck, L. F., Xuong, N. H., Taylor, S. S., and Sowadski, J. M. (1991) Science 253, 414-420
42. Siemeister, G., Al-Hasani, H., Klein, H. W., Kellner, S., Streicher, R., Krone, W., and Müller-Wieland, D. (1995) J. Biol. Chem. 270, 4870-4874
43. Hubbard, S. R., Mohammadi, M., and Schlessinger, J. (1998) J. Biol. Chem. 273, 11987-11990
44. Garrett, T. P., McKern, N. M., Lou, M., Elleman, T. C., Adams, T. E., Lovrecz, G. O., Zhu, H. J., Walker, F., Frenkel, M. J., Hoyne, P. A., Jorissen, R. N., Nice, E. C., Burgess, A. W., and Ward, C. W. (2002) Cell 110, 763-773
45. Ogiso, H., Ishitani, R., Nureki, O., Fukai, S., Yamanaka, M., Kim, J. H., Saito, K., Sakamoto, A., Inoue, M., Shirouzu, M., and Yokoyama, S. (2002) Cell 110, 775-787
46. Ferguson, K. M., Berger, M. B., Mendrola, J. M., Cho, H. S., Leahy, D. J., and Lemmon, M. A. (2003) Mol. Cell 11, 507-517
47. Koshland, D. E., Jr. (1998) Nat. Med. 4, 1112-1114
48. Fan, Y. X., Ju, M., Zhou, J. M., and Tsou, C. L. (1996) Biochem. J. 315, 97-99
49. Huse, M., and Kuriyan, J. (2002) Cell 109, 275-282
50. Schlessinger, J. (2003) Science 300, 750-752
51. Cai, T., Nishida, K., Hirano, T., and Khavari, P. A. (2002) J. Cell Biol. 159, 103-112
52. Salcini, A. E., McGlade, J., Pelicci, G., Nicoletti, I., Pawson, T., and Pelicci, P. G. (1994) Oncogene 9, 2827-2836
53. Batzer, A. G., Rotin, D., Urena, J. M., Skolnik, E. Y., and Schlessinger, J. (1994) Mol. Cell. Biol. 14, 5192-5201
54. Marshall, C. J. (1995) Cell 80, 179-185