IFN-γ/STAT1 acts as a proinflammatory signal in T cell-mediated hepatitis via induction of multiple chemokines and adhesion molecules: A critical role of IRF-1

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 287, Issue 5 50-5, 2004, Pages

  Jaruga, Barbara ^a   Hong, Feng ^a   Kim, Won Ho ^a   Gao, Bin ^a  

^a NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM   (United States)

Author keywords

Concanavalin A; Interferon ; Kupffer cells; Liver injury; Sinusoid epithelial cells

Indexed keywords

BETA CHEMOKINE; CC CHEMOKINE LIGAND 20; CELL ADHESION MOLECULE; CHEMOKINE; CONCANAVALIN A; EPITHELIAL DERIVED NEUTROPHIL ACTIVATING FACTOR 78; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERCELLULAR ADHESION MOLECULE 1; INTERFERON INDUCIBLE T CELL ALPHA CHEMOATTRACTANT PROTEIN; INTERFERON REGULATORY FACTOR 1; MESSENGER RNA; MONOKINE; PROTEIN; STAT1 PROTEIN; STAT3 PROTEIN; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; ENDOTHELIUM CELL; GENE; HEPATITIS; IN VIVO STUDY; INFLAMMATION; INJECTION; KUPFFER CELL; LEUKOCYTE; LIVER; LIVER CELL; LIVER INJURY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TARGETING; SIGNAL TRANSDUCTION; T LYMPHOCYTE; WILD TYPE;

ANIMALS; CELL ADHESION MOLECULES; CHEMOKINES; CONCANAVALIN A; DNA-BINDING PROTEINS; ENDOTHELIAL CELLS; EOSINOPHILS; HEPATITIS, ANIMAL; HEPATOCYTES; INFLAMMATION MEDIATORS; INTERFERON REGULATORY FACTOR-1; INTERFERON TYPE II; KUPFFER CELLS; LIVER; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEUTROPHIL INFILTRATION; PHOSPHOPROTEINS; SIGNAL TRANSDUCTION; STAT1 TRANSCRIPTION FACTOR; T-LYMPHOCYTES; TRANS-ACTIVATORS;

EID: 7044235774     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.00184.2004     Document Type: Article

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