The inhibition of lipopolysaccharide-induced tumor necrosis factor-α and nitric oxide production by Clostridium perfringens α-toxin and its relation to α-toxin-induced intracellular ceramide generation

International Journal of Medical Microbiology

Volumn 299, Issue 8, 2009, Pages 554-562

  Tumurkhuu, Gantsetseg ^a   Koide, Naoki ^a   Dagvadorj, Jargalsaikhan ^a   Shadat Mohammod Noman, Abu ^a   Iftekar E Khuda, Imtiaz ^a   Naiki, Yoshikazu ^a   Komatsu, Takayuki ^a   Yoshida, Tomoaki ^a   Oda, Masataka ^b   Nagahama, Masahiro ^b   Sakurai, Jun ^b   Yokochi, Takashi ^a  

^a AICHI MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b TOKUSHIMA BUNRI UNIVERSITY   (Japan)

Author keywords

Ceramide; Clostridium perfringens toxin; LPS; NF B; NO; TNF

Indexed keywords

BACTERIAL TOXIN; BETA GALACTOSIDASE; CERAMIDE; CLOSTRIDUM PERFRINGENS ALPHA TOXIN; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; LUCIFERASE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; NITRIC OXIDE; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVATION; MACROPHAGE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REPORTER GENE;

ANIMALS; BACTERIAL TOXINS; CALCIUM-BINDING PROTEINS; CELL LINE; CERAMIDES; GENE EXPRESSION REGULATION; GENES, REPORTER; I-KAPPA B KINASE; LIPOPOLYSACCHARIDES; LUCIFERASES; MACROPHAGES; MICE; NITRIC OXIDE; PHOSPHORYLATION; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR-ALPHA; TYPE C PHOSPHOLIPASES;

EID: 70350569387     PISSN: 14384221     EISSN: 16180607     Source Type: Journal    
DOI: 10.1016/j.ijmm.2009.04.003     Document Type: Article

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