-
1
-
-
0021564388
-
The cell biology of macrophage activation
-
Adams D.O., and Hamilton T.A. The cell biology of macrophage activation. Annu. Rev. Immunol. 2 (1984) 283-318
-
(1984)
Annu. Rev. Immunol.
, vol.2
, pp. 283-318
-
-
Adams, D.O.1
Hamilton, T.A.2
-
2
-
-
0037180768
-
The immunopathogenesis of sepsis
-
Cohen J. The immunopathogenesis of sepsis. Nature 420 (2002) 885-891
-
(2002)
Nature
, vol.420
, pp. 885-891
-
-
Cohen, J.1
-
3
-
-
0030694038
-
Biosynthesis and action of nitric oxide in mammalian cells
-
Mayer B., and Hemmens B. Biosynthesis and action of nitric oxide in mammalian cells. Trends Biochem. Sci. 22 (1997) 477-481
-
(1997)
Trends Biochem. Sci.
, vol.22
, pp. 477-481
-
-
Mayer, B.1
Hemmens, B.2
-
4
-
-
4644359359
-
Regulation of the expression of inducible nitric oxide synthase
-
Kleinert H., Pautz A., Linker K., and Schwarz P.M. Regulation of the expression of inducible nitric oxide synthase. Eur. J. Pharmacol. 500 (2004) 255-266
-
(2004)
Eur. J. Pharmacol.
, vol.500
, pp. 255-266
-
-
Kleinert, H.1
Pautz, A.2
Linker, K.3
Schwarz, P.M.4
-
5
-
-
0242552753
-
Molecular mechanisms of macrophage activation and deactivation by lipopolysaccharide: roles of the receptor complex
-
Fujihara M., Muroi M., Tanamoto K., Suzuki T., Azuma H., and Ikeda H. Molecular mechanisms of macrophage activation and deactivation by lipopolysaccharide: roles of the receptor complex. Pharmacol. Ther. 100 (2003) 171-194
-
(2003)
Pharmacol. Ther.
, vol.100
, pp. 171-194
-
-
Fujihara, M.1
Muroi, M.2
Tanamoto, K.3
Suzuki, T.4
Azuma, H.5
Ikeda, H.6
-
6
-
-
0035216928
-
Regulation of nuclear factor kappaB activation by G-protein-coupled receptors
-
Ye R.D. Regulation of nuclear factor kappaB activation by G-protein-coupled receptors. J. Leukocyte Biol. 70 (2001) 839-848
-
(2001)
J. Leukocyte Biol.
, vol.70
, pp. 839-848
-
-
Ye, R.D.1
-
7
-
-
0038311944
-
Phosphoinositide regulation of the actin cytoskeleton
-
Yin H.L., and Janmey P.A. Phosphoinositide regulation of the actin cytoskeleton. Annu. Rev. Physiol. 65 (2003) 761-789
-
(2003)
Annu. Rev. Physiol.
, vol.65
, pp. 761-789
-
-
Yin, H.L.1
Janmey, P.A.2
-
9
-
-
0031771547
-
Phosphoinositide signaling pathways in nuclei are associated with nuclear speckles containing pre-mRNA processing factors
-
Boronenkov I.V., Loijens J.C., Umeda M., and Anderson R.A. Phosphoinositide signaling pathways in nuclei are associated with nuclear speckles containing pre-mRNA processing factors. Mol. Biol. Cell 9 (1998) 3547-3560
-
(1998)
Mol. Biol. Cell
, vol.9
, pp. 3547-3560
-
-
Boronenkov, I.V.1
Loijens, J.C.2
Umeda, M.3
Anderson, R.A.4
-
10
-
-
27744608072
-
An emerging role for PtdIns(4,5)P2-mediated signalling in human disease
-
Halstead J.R., Jalink K., and Divecha N. An emerging role for PtdIns(4,5)P2-mediated signalling in human disease. Trends Pharmacol. Sci. 26 (2005) 654-660
-
(2005)
Trends Pharmacol. Sci.
, vol.26
, pp. 654-660
-
-
Halstead, J.R.1
Jalink, K.2
Divecha, N.3
-
11
-
-
0035347166
-
Back in the water: the return of the inositol phosphates
-
Irvine R.F., and Schell M.J. Back in the water: the return of the inositol phosphates. Nat. Rev., Mol. Cell Biol. 2 (2001) 327-338
-
(2001)
Nat. Rev., Mol. Cell Biol.
, vol.2
, pp. 327-338
-
-
Irvine, R.F.1
Schell, M.J.2
-
12
-
-
0036632368
-
The phosphatidylinositol 3-Kinase AKT pathway in human cancer
-
Vivanco I., and Sawyers C.L. The phosphatidylinositol 3-Kinase AKT pathway in human cancer. Nat. Rev., Cancer 2 (2002) 489-501
-
(2002)
Nat. Rev., Cancer
, vol.2
, pp. 489-501
-
-
Vivanco, I.1
Sawyers, C.L.2
-
14
-
-
0037088681
-
Phosphatidylinositol (3,4,5)P3 is essential but not sufficient for protein kinase B (PKB) activation; phosphatidylinositol (3,4)P2 is required for PKB phosphorylation at Ser-473: studies using cells from SH2-containing inositol-5-phosphatase knockout mice
-
Scheid M.P., Huber M., Damen J.F., Hughes M., Kang V., Neilsen P., Prestwich G.D., Krystal G., and Duronio V. Phosphatidylinositol (3,4,5)P3 is essential but not sufficient for protein kinase B (PKB) activation; phosphatidylinositol (3,4)P2 is required for PKB phosphorylation at Ser-473: studies using cells from SH2-containing inositol-5-phosphatase knockout mice. J. Biol. Chem. 277 (2002) 9027-9035
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 9027-9035
-
-
Scheid, M.P.1
Huber, M.2
Damen, J.F.3
Hughes, M.4
Kang, V.5
Neilsen, P.6
Prestwich, G.D.7
Krystal, G.8
Duronio, V.9
-
15
-
-
0031587403
-
Wortmannin, a specific inhibitor of phosphatidylinositol-3-kinase, enhances LPS-induced NO production from murine peritoneal macrophages
-
Park Y.C., Lee C.H., Kang H.S., Chung H.T., and Kim H.D. Wortmannin, a specific inhibitor of phosphatidylinositol-3-kinase, enhances LPS-induced NO production from murine peritoneal macrophages. Biochem. Biophys. Res. Commun. 240 (1997) 692-696
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.240
, pp. 692-696
-
-
Park, Y.C.1
Lee, C.H.2
Kang, H.S.3
Chung, H.T.4
Kim, H.D.5
-
16
-
-
0037199972
-
The phosphatidylinositol 3-kinase-Akt pathway limits lipopolysaccharide activation of signaling pathways and expression of inflammatory mediators in human monocytic cells
-
Guha M., and Mackman N. The phosphatidylinositol 3-kinase-Akt pathway limits lipopolysaccharide activation of signaling pathways and expression of inflammatory mediators in human monocytic cells. J. Biol. Chem. 277 (2002) 32124-32132
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 32124-32132
-
-
Guha, M.1
Mackman, N.2
-
17
-
-
0037031924
-
Phosphatidylinositol 3-kinase activity negatively regulates stability of cyclooxygenase 2 mRNA
-
Monick M.M., Robeff P.K., Butler N.S., Flaherty D.M., Carter A.B., Peterson M.W., and Hunninghake G.W. Phosphatidylinositol 3-kinase activity negatively regulates stability of cyclooxygenase 2 mRNA. J. Biol. Chem. 277 (2002) 32992-33000
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 32992-33000
-
-
Monick, M.M.1
Robeff, P.K.2
Butler, N.S.3
Flaherty, D.M.4
Carter, A.B.5
Peterson, M.W.6
Hunninghake, G.W.7
-
18
-
-
0033548627
-
Inhibition of phosphatidylinositol 3-kinase induces nitric-oxide synthase in lipopolysaccharide- or cytokine-stimulated C6 glial cells
-
Pahan K., Raymond J.R., and Singh I. Inhibition of phosphatidylinositol 3-kinase induces nitric-oxide synthase in lipopolysaccharide- or cytokine-stimulated C6 glial cells. J. Biol. Chem. 274 (1999) 7528-7536
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 7528-7536
-
-
Pahan, K.1
Raymond, J.R.2
Singh, I.3
-
19
-
-
12144288226
-
Up-regulation of IL-1 receptor through PI3K/Akt is essential for the induction of iNOS gene expression in hepatocytes
-
Teshima S., Nakanishi H., Nishizawa M., Kitagawa K., Kaibori M., Yamada M., Habara K., Kwon A.H., Kamiyama Y., Ito S., and Okumura T. Up-regulation of IL-1 receptor through PI3K/Akt is essential for the induction of iNOS gene expression in hepatocytes. J. Hepatol. 40 (2004) 616-623
-
(2004)
J. Hepatol.
, vol.40
, pp. 616-623
-
-
Teshima, S.1
Nakanishi, H.2
Nishizawa, M.3
Kitagawa, K.4
Kaibori, M.5
Yamada, M.6
Habara, K.7
Kwon, A.H.8
Kamiyama, Y.9
Ito, S.10
Okumura, T.11
-
20
-
-
0035379555
-
Akt stimulates the transactivation potential of the RelA/p65 Subunit of NF-kappa B through utilization of the Ikappa B kinase and activation of the mitogen-activated protein kinase p38
-
Madrid L.V., Mayo M.W., Reuther J.Y., and Baldwin Jr. A.S. Akt stimulates the transactivation potential of the RelA/p65 Subunit of NF-kappa B through utilization of the Ikappa B kinase and activation of the mitogen-activated protein kinase p38. J. Biol. Chem. 276 (2001) 18934-18940
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 18934-18940
-
-
Madrid, L.V.1
Mayo, M.W.2
Reuther, J.Y.3
Baldwin Jr., A.S.4
-
21
-
-
33644499125
-
Activating transcription factor 3 and early growth response 1 are the novel targets of LY294002 in a phosphatidylinositol 3-kinase-independent pathway
-
Yamaguchi K., Lee S.H., Kim J.S., Wimalasena J., Kitajima S., and Baek S.J. Activating transcription factor 3 and early growth response 1 are the novel targets of LY294002 in a phosphatidylinositol 3-kinase-independent pathway. Cancer Res. 66 (2006) 2376-2384
-
(2006)
Cancer Res.
, vol.66
, pp. 2376-2384
-
-
Yamaguchi, K.1
Lee, S.H.2
Kim, J.S.3
Wimalasena, J.4
Kitajima, S.5
Baek, S.J.6
-
22
-
-
0035313040
-
Lipopolysaccharide activates Akt in human alveolar macrophages resulting in nuclear accumulation and transcriptional activity of beta-catenin
-
Monick M.M., Carter A.B., Robeff P.K., Flaherty D.M., Peterson M.W., and Hunninghake G.W. Lipopolysaccharide activates Akt in human alveolar macrophages resulting in nuclear accumulation and transcriptional activity of beta-catenin. J. Immunol. 166 (2001) 2470-4713
-
(2001)
J. Immunol.
, vol.166
, pp. 2470-4713
-
-
Monick, M.M.1
Carter, A.B.2
Robeff, P.K.3
Flaherty, D.M.4
Peterson, M.W.5
Hunninghake, G.W.6
-
23
-
-
0032403566
-
Antisense oligonucleotides targeting protein kinase C-alpha,-beta I, or-delta but not-eta inhibit lipopolysaccharide-induced nitric oxide synthase expression in RAW 264.7 macrophages: involvement of a nuclear factor kappa B-dependent mechanism
-
Chen C.C., Wang J.K., and Lin S.B. Antisense oligonucleotides targeting protein kinase C-alpha,-beta I, or-delta but not-eta inhibit lipopolysaccharide-induced nitric oxide synthase expression in RAW 264.7 macrophages: involvement of a nuclear factor kappa B-dependent mechanism. J. Immunol. 161 (1998) 6206-6214
-
(1998)
J. Immunol.
, vol.161
, pp. 6206-6214
-
-
Chen, C.C.1
Wang, J.K.2
Lin, S.B.3
-
24
-
-
33748520173
-
Suppression of endotoxin-induced proinflammatory responses by citrus pectin through blocking LPS signaling pathways
-
Chen C.H., Sheu M.T., Chen T.F., Wang Y.C., Hou W.C., Liu D.Z., Chung T.C., and Liang Y.C. Suppression of endotoxin-induced proinflammatory responses by citrus pectin through blocking LPS signaling pathways. Biochem. Pharmacol. 72 (2006) 1001-1009
-
(2006)
Biochem. Pharmacol.
, vol.72
, pp. 1001-1009
-
-
Chen, C.H.1
Sheu, M.T.2
Chen, T.F.3
Wang, Y.C.4
Hou, W.C.5
Liu, D.Z.6
Chung, T.C.7
Liang, Y.C.8
-
25
-
-
1042289764
-
Apigenin induces apoptosis through proteasomal degradation of HER2/neu in HER2/neu-overexpressing breast cancer cells via the phosphatidylinositol 3-kinase/Akt-dependent pathway
-
Way T.D., Kao M.C., and Lin J.K. Apigenin induces apoptosis through proteasomal degradation of HER2/neu in HER2/neu-overexpressing breast cancer cells via the phosphatidylinositol 3-kinase/Akt-dependent pathway. J. Biol. Chem. 279 (2004) 4479-4489
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 4479-4489
-
-
Way, T.D.1
Kao, M.C.2
Lin, J.K.3
-
26
-
-
0027368278
-
Macrophage nitric oxide synthase gene: two upstream regions mediate induction by interferon γ and lipopolysaccharide
-
Lowenestein C.J., Alley E.W., Raval P., Snowman A.M., Snyder S.H., Russell S.W., and Murphy W.J. Macrophage nitric oxide synthase gene: two upstream regions mediate induction by interferon γ and lipopolysaccharide. Proc. Natl. Acad. Sci. U. S. A. 90 (1993) 9730-9734
-
(1993)
Proc. Natl. Acad. Sci. U. S. A.
, vol.90
, pp. 9730-9734
-
-
Lowenestein, C.J.1
Alley, E.W.2
Raval, P.3
Snowman, A.M.4
Snyder, S.H.5
Russell, S.W.6
Murphy, W.J.7
-
27
-
-
0035805144
-
Suppression of inducible cyclooxygenase and inducible nitric oxide synthase through peroxisome proliferator-activated receptor-γ by apigenin and related-flavonoids in macrophages
-
Liang Y.C., Tsai D.C., Lin-Shiau S.Y., Chen C.F., and Lin J.K. Suppression of inducible cyclooxygenase and inducible nitric oxide synthase through peroxisome proliferator-activated receptor-γ by apigenin and related-flavonoids in macrophages. FEBS Lett. 496 (2001) 12-18
-
(2001)
FEBS Lett.
, vol.496
, pp. 12-18
-
-
Liang, Y.C.1
Tsai, D.C.2
Lin-Shiau, S.Y.3
Chen, C.F.4
Lin, J.K.5
-
28
-
-
0031065203
-
Lipopolysaccharide-induced biphasic inositol 1,4,5-trisphosphate response and tyrosine phosphorylation of 140-kilodalton protein in mouse peritoneal macrophages
-
Shinji H., Akagawa K.S., Tsuji M., Maeda M., Yamada R., Matsuura K., Yamamoto S., and Yoshida T. Lipopolysaccharide-induced biphasic inositol 1,4,5-trisphosphate response and tyrosine phosphorylation of 140-kilodalton protein in mouse peritoneal macrophages. J. Immunol. 158 (1997) 1370-1376
-
(1997)
J. Immunol.
, vol.158
, pp. 1370-1376
-
-
Shinji, H.1
Akagawa, K.S.2
Tsuji, M.3
Maeda, M.4
Yamada, R.5
Matsuura, K.6
Yamamoto, S.7
Yoshida, T.8
-
29
-
-
0242593867
-
Ketamine inhibits endotoxin-induced inositol 1,4,5-triphosphate in rat ventricular cardiomyocytes
-
Kudoh A., Katagai H., and Takazawa T. Ketamine inhibits endotoxin-induced inositol 1,4,5-triphosphate in rat ventricular cardiomyocytes. Int. Care Med. 29 (2003) 1812-1817
-
(2003)
Int. Care Med.
, vol.29
, pp. 1812-1817
-
-
Kudoh, A.1
Katagai, H.2
Takazawa, T.3
-
30
-
-
6344222886
-
LY-294002 [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one] affects calcium signaling in airway smooth muscle cells independently of phosphoinositide 3-kinase inhibition
-
Tolloczko B., Turkewitsch P., Al-Chalabi M., and Martin J.G. LY-294002 [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one] affects calcium signaling in airway smooth muscle cells independently of phosphoinositide 3-kinase inhibition. J. Pharmacol. Exp. Ther. 311 (2004) 787-793
-
(2004)
J. Pharmacol. Exp. Ther.
, vol.311
, pp. 787-793
-
-
Tolloczko, B.1
Turkewitsch, P.2
Al-Chalabi, M.3
Martin, J.G.4
-
31
-
-
0037469744
-
The phosphatidylinositol 3-kinase inhibitor LY294002 binds the estrogen receptor and inhibits 17h-estradiol-induced transcriptional activity of an estrogen sensitive reporter gene
-
Pasapera Limon A.M., Herrera-Munoz J., Gutierrez-Sagal R., and Ulloa-Aguirre A. The phosphatidylinositol 3-kinase inhibitor LY294002 binds the estrogen receptor and inhibits 17h-estradiol-induced transcriptional activity of an estrogen sensitive reporter gene. Mol. Cell Endocrinol. 200 (2003) 199-202
-
(2003)
Mol. Cell Endocrinol.
, vol.200
, pp. 199-202
-
-
Pasapera Limon, A.M.1
Herrera-Munoz, J.2
Gutierrez-Sagal, R.3
Ulloa-Aguirre, A.4
-
32
-
-
0442323485
-
LY294002 inhibits monocyte chemoattractant protein-1 expression through a phosphatidylinositol 3-kinase-independent mechanism
-
Choi E.K., Park H.J., Ma J.S., Lee H.C., Kang H.C., Kim B.G., and Kang I.C. LY294002 inhibits monocyte chemoattractant protein-1 expression through a phosphatidylinositol 3-kinase-independent mechanism. FEBS Lett. 559 (2004) 141-144
-
(2004)
FEBS Lett.
, vol.559
, pp. 141-144
-
-
Choi, E.K.1
Park, H.J.2
Ma, J.S.3
Lee, H.C.4
Kang, H.C.5
Kim, B.G.6
Kang, I.C.7
-
33
-
-
33845973015
-
Ca2+- and protein kinase C-dependent signaling pathway for nuclear factor-kappa B activation, inducible nitric oxide synthase expression, and tumor necrosis factor-alpha production in lipopolysaccharide-stimulated rat peritoneal macrophages
-
Zhou X., Yang W., and Li J. Ca2+- and protein kinase C-dependent signaling pathway for nuclear factor-kappa B activation, inducible nitric oxide synthase expression, and tumor necrosis factor-alpha production in lipopolysaccharide-stimulated rat peritoneal macrophages. J. Biol. Chem. 281 (2006) 31337-31347
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 31337-31347
-
-
Zhou, X.1
Yang, W.2
Li, J.3
-
34
-
-
1542317022
-
Ca2+/calmodulin-dependent protein phosphatase calcineurin mediates the expression of iNOS through IKK and NF-kappaB activity in LPS-stimulated mouse peritoneal macrophages and RAW 264.7 cells
-
Kim Y., Moon J.S., Lee K.S., Park S.Y., Cheong J., Kang H.S., Lee H.Y., and Kim H.D. Ca2+/calmodulin-dependent protein phosphatase calcineurin mediates the expression of iNOS through IKK and NF-kappaB activity in LPS-stimulated mouse peritoneal macrophages and RAW 264.7 cells. Biochem. Biophys. Res. Commun. 314 (2004) 695-703
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.314
, pp. 695-703
-
-
Kim, Y.1
Moon, J.S.2
Lee, K.S.3
Park, S.Y.4
Cheong, J.5
Kang, H.S.6
Lee, H.Y.7
Kim, H.D.8
-
35
-
-
13344284662
-
Regulation of inducible nitric oxide synthase expression by macrophage purinoreceptors and calcium
-
Denlinger L.C., Fisette P.L., Garis K.A., Kwon G., Vazquez-Torres A., Simon A.D., Nguyen B., Proctor R.A., Bertics P.J., and Corbett J.A. Regulation of inducible nitric oxide synthase expression by macrophage purinoreceptors and calcium. J. Biol. Chem. 271 (1996) 337-342
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 337-342
-
-
Denlinger, L.C.1
Fisette, P.L.2
Garis, K.A.3
Kwon, G.4
Vazquez-Torres, A.5
Simon, A.D.6
Nguyen, B.7
Proctor, R.A.8
Bertics, P.J.9
Corbett, J.A.10
-
36
-
-
0028978604
-
Increased intracellular Ca2+ selectively suppresses IL-1-induced NO production by reducing iNOS mRNA stability
-
Geng Y., and Lotz M. Increased intracellular Ca2+ selectively suppresses IL-1-induced NO production by reducing iNOS mRNA stability. J. Cell Biol. 129 (1995) 1651-1657
-
(1995)
J. Cell Biol.
, vol.129
, pp. 1651-1657
-
-
Geng, Y.1
Lotz, M.2
-
37
-
-
0028228399
-
Methylxanthines and calcium-mobilizing agents inhibit the expression of cytokine-inducible nitric oxide synthase and vascular cell adhesion molecule-1 in murine microvascular endothelial cells
-
Bereta M., Bereta J., Georgoff I., Coffman F.D., Cohen S., and Cohen M.C. Methylxanthines and calcium-mobilizing agents inhibit the expression of cytokine-inducible nitric oxide synthase and vascular cell adhesion molecule-1 in murine microvascular endothelial cells. Exp. Cell Res. 212 (1994) 230-242
-
(1994)
Exp. Cell Res.
, vol.212
, pp. 230-242
-
-
Bereta, M.1
Bereta, J.2
Georgoff, I.3
Coffman, F.D.4
Cohen, S.5
Cohen, M.C.6
-
38
-
-
0035399943
-
TNF-alpha-induced sphingosine 1-phosphate inhibits apoptosis through a phosphatidylinositol 3-kinase/Akt pathway in human hepatocytes
-
Osawa Y., Banno Y., Nagaki M., Brenner D.A., Naiki T., Nozawa Y., Nakashima S., and Moriwaki H. TNF-alpha-induced sphingosine 1-phosphate inhibits apoptosis through a phosphatidylinositol 3-kinase/Akt pathway in human hepatocytes. J. Immunol. 167 (2001) 173-180
-
(2001)
J. Immunol.
, vol.167
, pp. 173-180
-
-
Osawa, Y.1
Banno, Y.2
Nagaki, M.3
Brenner, D.A.4
Naiki, T.5
Nozawa, Y.6
Nakashima, S.7
Moriwaki, H.8
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