Role of tyrosine-57 and -65 in membrane-damaging and sphingomyelinase activities of Clostridium perfringens alpha-toxin

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1762, Issue 1, 2006, Pages 110-114

  Nagahama, Masahiro ^a   Otsuka, Akiko ^a   Sakurai, Jun ^a  

^a TOKUSHIMA BUNRI UNIVERSITY   (Japan)

Author keywords

Alpha toxin; Clostridium perfringens; Hemolytic activity; Liposome; Sphingomyelinase

Indexed keywords

ALANINE; ALPHA TOXIN; CALCIUM BINDING PROTEIN; CARBOXYFLUORESCEIN; CHOLESTEROL; DEOXYCHOLATE SODIUM; LEUCINE; PHENYLALANINE; SPHINGOMYELIN; SPHINGOMYELIN PHOSPHODIESTERASE; TYROSINE;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CLOSTRIDIUM PERFRINGENS; ENVIRONMENT; ENZYME ACTIVITY; ERYTHROCYTE; GAS GANGRENE; HEMOLYSIS; HYDROPHOBICITY; MEMBRANE DAMAGE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; SENSITIVITY ANALYSIS; VIRULENCE;

2-NAPHTHYLAMINE; ANIMALS; BACTERIAL TOXINS; CALCIUM-BINDING PROTEINS; CELL MEMBRANE; CIRCULAR DICHROISM; ERYTHROCYTES; LIPOSOMES; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PHOSPHOLIPASE C; PROTEIN BINDING; SHEEP; SPHINGOMYELIN PHOSPHODIESTERASE; TYROSINE;

CLOSTRIDIUM PERFRINGENS; OVIS ARIES;

EID: 29644435330     PISSN: 09254439     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbadis.2005.10.002     Document Type: Article

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