메뉴 건너뛰기




Volumn 34, Issue 4, 2009, Pages 573-590

Biomicrofluidics: Recent trends and future challenges

Author keywords

Biomicrofluidics; Lab on a chip; Micro total analysis system ( TAS); Microfluidics

Indexed keywords

ACTIVE AREA; BIOMEDICAL MICRODEVICES; BIOMICROFLUIDICS; FUTURE CHALLENGES; FUTURE DIRECTIONS; LAB-ON-A-CHIP; RECENT TRENDS;

EID: 70350551831     PISSN: 02562499     EISSN: 09737677     Source Type: Journal    
DOI: 10.1007/s12046-009-0035-8     Document Type: Article
Times cited : (25)

References (119)
  • 2
    • 0030142076 scopus 로고    scopus 로고
    • Generation of transverse fluid currents and forces by an electric field: Electro-osmosis on charge-modulated and undulate surfaces
    • Ajdari A 1996 Generation of transverse fluid currents and forces by an electric field: Electro-osmosis on charge-modulated and undulate surfaces. Phys. Rev. E. 53: 4996-5005.
    • (1996) Phys. Rev. E. , vol.53 , pp. 4996-5005
    • Ajdari, A.1
  • 3
    • 29644444524 scopus 로고    scopus 로고
    • Transverse electrokinetic and microfluidic effects in micropatterned channels: Lubrication analysis for slab geometries
    • 016301
    • Ajdari A 2002 Transverse electrokinetic and microfluidic effects in micropatterned channels: Lubrication analysis for slab geometries. Phys. Rev. E. 65: 016301 (1-9).
    • (2002) Phys. Rev. E. , vol.65 , pp. 1-9
    • Ajdari, A.1
  • 4
    • 1942502193 scopus 로고    scopus 로고
    • Microfabrication and microfluidics for tissue engineering: State of the art and future opportunities
    • Andersson H, van der Berg A 2004 Microfabrication and microfluidics for tissue engineering: State of the art and future opportunities. Lab Chip 4: 98-103.
    • (2004) Lab Chip , vol.4 , pp. 98-103
    • Andersson, H.1    van der Berg, A.2
  • 5
    • 0034250670 scopus 로고    scopus 로고
    • Micromachined Flow-through Filter-Chamber for Chemical Reactions on Beads
    • Andersson H, Wijngaart W, Enoksson P, Stemme G 2000 Micromachined Flow-through Filter-Chamber for Chemical Reactions on Beads. Sens. Actuators B67: 203-208.
    • (2000) Sens. Actuators , vol.B67 , pp. 203-208
    • Andersson, H.1    Wijngaart, W.2    Enoksson, P.3    Stemme, G.4
  • 6
    • 0642340797 scopus 로고    scopus 로고
    • RNA biosensor for the rapid detection of viable Escherichia coli in drinking water
    • Baeumner A J, Cohen R N, Miksic V, Min J H 2003 RNA biosensor for the rapid detection of viable Escherichia coli in drinking water. Biosens. Bioelectron. 18: 405-413.
    • (2003) Biosens. Bioelectron. , vol.18 , pp. 405-413
    • Baeumner, A.J.1    Cohen, R.N.2    Miksic, V.3    Min, J.H.4
  • 7
    • 0035866667 scopus 로고    scopus 로고
    • Detection of viable oocysts of Cryptosporidium parvum following nucleic acid sequence based amplification
    • Baeumner A J, Humiston M C, Montagna R A, Durst R A 2001 Detection of viable oocysts of Cryptosporidium parvum following nucleic acid sequence based amplification. Anal. Chem. 73: 1176-1180.
    • (2001) Anal. Chem. , vol.73 , pp. 1176-1180
    • Baeumner, A.J.1    Humiston, M.C.2    Montagna, R.A.3    Durst, R.A.4
  • 9
    • 21644441288 scopus 로고    scopus 로고
    • Long-term monitoring of bacteria undergoing programmed population control in a microchemostat
    • Balagadde F K, You L C, Hansen C L, Arnold F H, Quake S R 2005 Long-term monitoring of bacteria undergoing programmed population control in a microchemostat. Science 309: 137-140.
    • (2005) Science , vol.309 , pp. 137-140
    • Balagadde, F.K.1    You, L.C.2    Hansen, C.L.3    Arnold, F.H.4    Quake, S.R.5
  • 10
    • 33750446270 scopus 로고    scopus 로고
    • Theoretical prediction of fast 3D AC electro-osmotic pumps
    • Bazant M Z, Ben Y 2006 Theoretical prediction of fast 3D AC electro-osmotic pumps. Lab Chip 6: 1455-1461.
    • (2006) Lab Chip , vol.6 , pp. 1455-1461
    • Bazant, M.Z.1    Ben, Y.2
  • 12
    • 0035356575 scopus 로고    scopus 로고
    • Evaluation of three-dimensional microchannel glass biochips for multiplexed nucleic acid fluorescence hybridization assays
    • Benoit V, Steel A, Torres M, Lu Y Y, Yang H J, Cooper J 2001 Evaluation of three-dimensional microchannel glass biochips for multiplexed nucleic acid fluorescence hybridization assays. Anal. Chem. 73: 2412-2420.
    • (2001) Anal. Chem. , vol.73 , pp. 2412-2420
    • Benoit, V.1    Steel, A.2    Torres, M.3    Lu, Y.Y.4    Yang, H.J.5    Cooper, J.6
  • 13
    • 0030673034 scopus 로고    scopus 로고
    • Real time measurement of nucleic acid hybridization using evanescent wave sensors-steps towards the genosensor
    • Bier F F, Kleinjung F, Scheller FW 1997 Real time measurement of nucleic acid hybridization using evanescent wave sensors-steps towards the genosensor. Sens. Actuators 38B: 78-82.
    • (1997) Sens. Actuators , vol.38 B , pp. 78-82
    • Bier, F.F.1    Kleinjung, F.2    Scheller, F.W.3
  • 16
    • 0042045214 scopus 로고    scopus 로고
    • Whole cell biosensors
    • Bousse L 1996 Whole cell biosensors. Sens. Actuators B Chem. 34: 270-275.
    • (1996) Sens. Actuators B Chem. , vol.34 , pp. 270-275
    • Bousse, L.1
  • 17
    • 84984932472 scopus 로고    scopus 로고
    • Exploring the new world of the genome with DNA microarrays
    • Brown P, Botstein D 1999 Exploring the new world of the genome with DNA microarrays. Nat. Genet. 21: 33-37.
    • (1999) Nat. Genet. , vol.21 , pp. 33-37
    • Brown, P.1    Botstein, D.2
  • 18
    • 34548424139 scopus 로고    scopus 로고
    • Order parameter modelling of fluid dynamics in narrow confinements subjected to hydrophobic interactions
    • 094504
    • Chakraborty S 2007a Order parameter modelling of fluid dynamics in narrow confinements subjected to hydrophobic interactions. Phys. Rev. Lett. 99: 094504 (1-4).
    • (2007) Phys. Rev. Lett. , vol.99 , pp. 1-4
    • Chakraborty, S.1
  • 19
    • 33846463381 scopus 로고    scopus 로고
    • Towards a generalized representation of surface effects on pressure-driven liquid flow in microchannels
    • 034108
    • Chakraborty S 2007b Towards a generalized representation of surface effects on pressure-driven liquid flow in microchannels. Appl. Phys. Lett. 90: 034108 (1-3).
    • (2007) Appl. Phys. Lett. , vol.90 , pp. 1-3
    • Chakraborty, S.1
  • 21
    • 34547924455 scopus 로고    scopus 로고
    • Electrokinetic mixing in microfluidic systems
    • Chang C C, Yang R J 2007 Electrokinetic mixing in microfluidic systems. Microfluid. Nanofluid. 3: 501-525.
    • (2007) Microfluid. Nanofluid. , vol.3 , pp. 501-525
    • Chang, C.C.1    Yang, R.J.2
  • 22
    • 12344338240 scopus 로고    scopus 로고
    • Biomimetic technique for adhesion-based collection and separation of cells in a microfluidic channel
    • Chang W C, Lee L P, Liepmann D 2005 Biomimetic technique for adhesion-based collection and separation of cells in a microfluidic channel. Lab Chip 5: 64-73.
    • (2005) Lab Chip , vol.5 , pp. 64-73
    • Chang, W.C.1    Lee, L.P.2    Liepmann, D.3
  • 23
    • 0031214943 scopus 로고    scopus 로고
    • A multichannel neural probe for selective chemical delivery at the cellular level
    • Chen J, Wise K D 1997 A multichannel neural probe for selective chemical delivery at the cellular level. IEEE Trans. Biomed. Eng. 44: 760-769.
    • (1997) IEEE Trans. Biomed. Eng. , vol.44 , pp. 760-769
    • Chen, J.1    Wise, K.D.2
  • 24
    • 17444378999 scopus 로고    scopus 로고
    • DNA separation by EFFF in a microchannel
    • Chen Z, Chauhan A 2005 DNA separation by EFFF in a microchannel. J. Colloid Interface Sci. 285: 834-844.
    • (2005) J. Colloid Interface Sci. , vol.285 , pp. 834-844
    • Chen, Z.1    Chauhan, A.2
  • 25
    • 0031081614 scopus 로고    scopus 로고
    • Microchip-based capillary electrophoresis for immunoassays: Analysis of monoclonal antibodies and theophylline
    • Chiem N, Harrison D J 1997 Microchip-based capillary electrophoresis for immunoassays: Analysis of monoclonal antibodies and theophylline. Anal. Chem. 69: 373-378.
    • (1997) Anal. Chem. , vol.69 , pp. 373-378
    • Chiem, N.1    Harrison, D.J.2
  • 28
    • 33746230290 scopus 로고    scopus 로고
    • Modelling of coupled momentum, heat and solute Transport during DNA hybridization in a microchannel in presence of electro-osmotic effects and axial pressure gradients
    • Das S, Das T, Chakraborty S 2006 Modelling of coupled momentum, heat and solute Transport during DNA hybridization in a microchannel in presence of electro-osmotic effects and axial pressure gradients. Microfluid. Nanofluid. 2: 37-49.
    • (2006) Microfluid. Nanofluid. , vol.2 , pp. 37-49
    • Das, S.1    Das, T.2    Chakraborty, S.3
  • 29
    • 0036815756 scopus 로고    scopus 로고
    • New approaches to high-throughput phasing
    • Dauter Z 2002 New approaches to high-throughput phasing. Curr. Opin. Struct. Biol. 12: 674-678.
    • (2002) Curr. Opin. Struct. Biol. , vol.12 , pp. 674-678
    • Dauter, Z.1
  • 30
    • 2942716734 scopus 로고    scopus 로고
    • Insertion of microneedles into skin: Measurement and prediction of insertion force and needle fracture force
    • Davis S P, Landis B J, Adams Z H, Allen M G, Prausnitz M R 2004 Insertion of microneedles into skin: Measurement and prediction of insertion force and needle fracture force. J. Biomech. 37: 1155-1163.
    • (2004) J. Biomech. , vol.37 , pp. 1155-1163
    • Davis, S.P.1    Landis, B.J.2    Adams, Z.H.3    Allen, M.G.4    Prausnitz, M.R.5
  • 31
    • 0141615139 scopus 로고    scopus 로고
    • Dealing with 'real' samples: Sample pre-treatment in microfluidic systems
    • deMello A J, Beard N 2003 Dealing with 'real' samples: Sample pre-treatment in microfluidic systems. Lab Chip 3: 11N-19N.
    • (2003) Lab Chip , vol.3
    • deMello, A.J.1    Beard, N.2
  • 32
    • 0034866512 scopus 로고    scopus 로고
    • Portable cell-based biosensor system using integrated CMOS cell-cartridges
    • DeBusschere B D, Kovacs G T A 2001 Portable cell-based biosensor system using integrated CMOS cell-cartridges. Biosens. Bioelectron. 16: 543-556.
    • (2001) Biosens. Bioelectron. , vol.16 , pp. 543-556
    • DeBusschere, B.D.1    Kovacs, G.T.A.2
  • 33
    • 33644777646 scopus 로고    scopus 로고
    • Lab-on-a-chip: Microfluidics in drug discovery
    • Dittrich P S, Manz A 2006 Lab-on-a-chip: Microfluidics in drug discovery. Nat. Rev. Drug Discov. 5: 210-218.
    • (2006) Nat. Rev. Drug Discov. , vol.5 , pp. 210-218
    • Dittrich, P.S.1    Manz, A.2
  • 36
    • 0344062629 scopus 로고    scopus 로고
    • Three-dimensional structure of electroosmotic flow over heterogeneous surfaces
    • Erickson D, Li D 2003 Three-dimensional structure of electroosmotic flow over heterogeneous surfaces. J. Phys. Chem. 107: 12212-12220.
    • (2003) J. Phys. Chem. , vol.107 , pp. 12212-12220
    • Erickson, D.1    Li, D.2
  • 37
    • 34247593952 scopus 로고    scopus 로고
    • Digital microfluidics: Is a true lab-on-a-chip possible?
    • Fair R B 2007 Digital microfluidics: Is a true lab-on-a-chip possible? Microfluid. Nanofluid. 3: 245-281.
    • (2007) Microfluid. Nanofluid. , vol.3 , pp. 245-281
    • Fair, R.B.1
  • 39
    • 0034578083 scopus 로고    scopus 로고
    • Microengineering of cellular interactions
    • Folch A, Toner M 2000 Microengineering of cellular interactions. Annu. Rev. Biomed. Eng. 2: 227-256.
    • (2000) Annu. Rev. Biomed. Eng. , vol.2 , pp. 227-256
    • Folch, A.1    Toner, M.2
  • 41
    • 4344645067 scopus 로고    scopus 로고
    • Dielectrophoresis-based sample handling in general-purpose programmable diagnostic instruments
    • Gascoyne P R C, Vykoukal J V 2004 Dielectrophoresis-based sample handling in general-purpose programmable diagnostic instruments. Proc. IEEE 92: 22-42.
    • (2004) Proc. IEEE , vol.92 , pp. 22-42
    • Gascoyne, P.R.C.1    Vykoukal, J.V.2
  • 42
    • 0032738605 scopus 로고    scopus 로고
    • Microfluidic assays of acetylcholinesterase inhibitors
    • Hadd A, Jacobson S, Ramsey J 1999 Microfluidic assays of acetylcholinesterase inhibitors. Anal. Chem. 71: 5206-5212.
    • (1999) Anal. Chem. , vol.71 , pp. 5206-5212
    • Hadd, A.1    Jacobson, S.2    Ramsey, J.3
  • 44
    • 0034640410 scopus 로고    scopus 로고
    • Separation of long DNA molecules in a microfabricated entropic trap array
    • Han J, Craighead H G 2000 Separation of long DNA molecules in a microfabricated entropic trap array. Science 288: 1026-1029.
    • (2000) Science , vol.288 , pp. 1026-1029
    • Han, J.1    Craighead, H.G.2
  • 45
    • 0141557513 scopus 로고    scopus 로고
    • Microfluidics in structural biology: Smaller, faster ... better
    • Hansen C, Quake S R 2003 Microfluidics in structural biology: Smaller, faster ... better. Cur. Opin. Struct. Biol. 13: 538-544.
    • (2003) Cur. Opin. Struct. Biol. , vol.13 , pp. 538-544
    • Hansen, C.1    Quake, S.R.2
  • 46
    • 0037168508 scopus 로고    scopus 로고
    • A robust and scalable microfluidic metering method that allows protein crystal growth by free interface diffusion
    • Hansen C L, Skordalakes E, Berger J M, Quake S R 2002 A robust and scalable microfluidic metering method that allows protein crystal growth by free interface diffusion. Proc. Natl. Acad. Sci. USA 99: 16531-16536.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 16531-16536
    • Hansen, C.L.1    Skordalakes, E.2    Berger, J.M.3    Quake, S.R.4
  • 47
    • 20444410002 scopus 로고    scopus 로고
    • Passive micromixers for applications in the microreactor and μ TAS fields
    • Hardt S, Drese K S, Hessel V, Schönfeld F 2005 Passive micromixers for applications in the microreactor and μ TAS fields. Microfluid. Nanofluid. 1: 108-11.
    • (2005) Microfluid. Nanofluid. , vol.1 , pp. 108-11
    • Hardt, S.1    Drese, K.S.2    Hessel, V.3    Schönfeld, F.4
  • 48
    • 0033621575 scopus 로고    scopus 로고
    • Active microelectronic chip devices which utilize controlled electrophoretic fields for multiplexDNAhybridization and other genomic applications
    • Heller M J, Forster A H, Tu E 2000 Active microelectronic chip devices which utilize controlled electrophoretic fields for multiplexDNAhybridization and other genomic applications. Electrophoresis 21: 157-164.
    • (2000) Electrophoresis , vol.21 , pp. 157-164
    • Heller, M.J.1    Forster, A.H.2    Tu, E.3
  • 49
    • 4043062080 scopus 로고    scopus 로고
    • Photopolymerized cross-linked polyacrylamide gels for on-chip protein sizing
    • Herr A E, Singh A K 2004 Photopolymerized cross-linked polyacrylamide gels for on-chip protein sizing. Anal. Chem. 76: 4727-4733.
    • (2004) Anal. Chem. , vol.76 , pp. 4727-4733
    • Herr, A.E.1    Singh, A.K.2
  • 50
    • 0037346348 scopus 로고    scopus 로고
    • Laminar mixing in different interdigital micromixers: I. Experimental characterization
    • Hessel V, Hardt S, Lowe H, Schönfeld F 2003 Laminar mixing in different interdigital micromixers: I. Experimental characterization. AIChE J. 49: 566-577.
    • (2003) AIChE J. , vol.49 , pp. 566-577
    • Hessel, V.1    Hardt, S.2    Lowe, H.3    Schönfeld, F.4
  • 51
    • 27844509988 scopus 로고    scopus 로고
    • Microfabricated drug delivery devices
    • Hilt J Z, Peppas N A 2005 Microfabricated drug delivery devices. Int. J. Pharmaceutics 306: 15-23.
    • (2005) Int. J. Pharmaceutics , vol.306 , pp. 15-23
    • Hilt, J.Z.1    Peppas, N.A.2
  • 52
    • 21244476314 scopus 로고    scopus 로고
    • Microfluidic tools for studying the specific binding, adsorption, and displacement of proteins at interfaces
    • Holden M A, Cremer P S 2005 Microfluidic tools for studying the specific binding, adsorption, and displacement of proteins at interfaces. Annu. Rev. Phys. Chem. 56: 369-387.
    • (2005) Annu. Rev. Phys. Chem. , vol.56 , pp. 369-387
    • Holden, M.A.1    Cremer, P.S.2
  • 54
    • 12144263348 scopus 로고    scopus 로고
    • Continuous perfusion microfluidic cell culture array for high-throughput cell-based assays
    • Huang P J, Lee P J, Sabounchi P, Lin R, Lee L P 2005 Continuous perfusion microfluidic cell culture array for high-throughput cell-based assays. Biotechnol. Bioeng. 89: 1-8.
    • (2005) Biotechnol. Bioeng. , vol.89 , pp. 1-8
    • Huang, P.J.1    Lee, P.J.2    Sabounchi, P.3    Lin, R.4    Lee, L.P.5
  • 55
    • 33744547472 scopus 로고    scopus 로고
    • Micromixer Based On Taylor Dispersion
    • Huiqian Y, Nguyen N T, Huang X 2006 Micromixer Based On Taylor Dispersion. J. Phys. 34: 136-141.
    • (2006) J. Phys. , vol.34 , pp. 136-141
    • Huiqian, Y.1    Nguyen, N.T.2    Huang, X.3
  • 56
    • 0041836115 scopus 로고    scopus 로고
    • Micro-pattering by Wettability Control of SiO2 Surface with Ultraviolet Irradiation
    • Huang L, Zhang Y, Liao J H, Xu L N, Gu N, Shen H J 2003 Micro-pattering by Wettability Control of SiO2 Surface with Ultraviolet Irradiation. Surf. Rev. Lett. 10: 569-570.
    • (2003) Surf. Rev. Lett. , vol.10 , pp. 569-570
    • Huang, L.1    Zhang, Y.2    Liao, J.H.3    Xu, L.N.4    Gu, N.5    Shen, H.J.6
  • 59
    • 0028932361 scopus 로고
    • Microchip Electrophoresis with Sample Stacking
    • Jacobson S C, Ramsey J M 1995 Microchip Electrophoresis with Sample Stacking. Electrophoresis 16: 481-486.
    • (1995) Electrophoresis , vol.16 , pp. 481-486
    • Jacobson, S.C.1    Ramsey, J.M.2
  • 60
    • 0036022527 scopus 로고    scopus 로고
    • Neutrophil chemotaxis in linear and complex gradients of interleukin-8 formed in a microfabricated device
    • Jeon N L, Baskaran H, Dertinger S K W, Whitesides G M, Water L V D, Toner M 2002 Neutrophil chemotaxis in linear and complex gradients of interleukin-8 formed in a microfabricated device. Nat. Biotech. 20: 826-830.
    • (2002) Nat. Biotech. , vol.20 , pp. 826-830
    • Jeon, N.L.1    Baskaran, H.2    Dertinger, S.K.W.3    Whitesides, G.M.4    Water, L.V.D.5    Toner, M.6
  • 62
    • 29244448286 scopus 로고    scopus 로고
    • Characterization of DNA hybridization kinetics in a microfluidic flow channel
    • Kim J H S, Marafie A, Jia X Y, Zoval J V, Madou M J 2006 Characterization of DNA hybridization kinetics in a microfluidic flow channel. Sens. Actuators B113: 281-289.
    • (2006) Sens. Actuators , vol.B113 , pp. 281-289
    • Kim, J.H.S.1    Marafie, A.2    Jia, X.Y.3    Zoval, J.V.4    Madou, M.J.5
  • 63
    • 33644648070 scopus 로고    scopus 로고
    • Microfluidic arrays for logarithmically perfused embryonic stem cell culture
    • Kim L, Vahey M D, Lee H Y, Voldman J 2006 Microfluidic arrays for logarithmically perfused embryonic stem cell culture. Lab Chip 6: 394-406.
    • (2006) Lab Chip , vol.6 , pp. 394-406
    • Kim, L.1    Vahey, M.D.2    Lee, H.Y.3    Voldman, J.4
  • 64
    • 0002158419 scopus 로고    scopus 로고
    • Determination of Metal Cations in Microchip Electrophoresis using On-Chip Complexation and Sample Stacking
    • Kutter J P, Ramsey R S, Jacobson S C, Ramsey J M 1998 Determination of Metal Cations in Microchip Electrophoresis using On-Chip Complexation and Sample Stacking. J. Microcolumn Sep. 10: 313-319.
    • (1998) J. Microcolumn Sep. , vol.10 , pp. 313-319
    • Kutter, J.P.1    Ramsey, R.S.2    Jacobson, S.C.3    Ramsey, J.M.4
  • 66
    • 0346256860 scopus 로고    scopus 로고
    • Advances in biomaterials, drug delivery, and bionanotechnology
    • Langer R, Peppas N A 2003 Advances in biomaterials, drug delivery, and bionanotechnology. AIChE J. 49: 2990-3006.
    • (2003) AIChE J. , vol.49 , pp. 2990-3006
    • Langer, R.1    Peppas, N.A.2
  • 68
    • 0036141528 scopus 로고    scopus 로고
    • Electrowetting and electrowetting-on-dielectric for microscale liquid handling
    • Lee J, Moon H, Fowler J, Schoellhammer T, Kim C J 2002 Electrowetting and electrowetting-on-dielectric for microscale liquid handling. Sens. Actuators A95: 259-268.
    • (2002) Sens. Actuators , vol.A95 , pp. 259-268
    • Lee, J.1    Moon, H.2    Fowler, J.3    Schoellhammer, T.4    Kim, C.J.5
  • 69
    • 34548588442 scopus 로고    scopus 로고
    • Poly(dimethylsiloxane)-based protein preconcentration using a nanogap generated by junction gap breakdown
    • Lee J H, Chung S, Kim S J, Han J 2007 Poly(dimethylsiloxane)-based protein preconcentration using a nanogap generated by junction gap breakdown. Anal. Chem. 79: 6868-6873.
    • (2007) Anal. Chem. , vol.79 , pp. 6868-6873
    • Lee, J.H.1    Chung, S.2    Kim, S.J.3    Han, J.4
  • 71
    • 0031569477 scopus 로고    scopus 로고
    • Transport, manipulation, and reaction of biological cells on-chip using electrokinetic effects
    • Li P C H, Harrison D J 1997 Transport, manipulation, and reaction of biological cells on-chip using electrokinetic effects. Anal. Chem. 69: 1564-1568.
    • (1997) Anal. Chem. , vol.69 , pp. 1564-1568
    • Li, P.C.H.1    Harrison, D.J.2
  • 72
    • 3142694728 scopus 로고    scopus 로고
    • Generation of dynamic temporal and spatial concentration gradients using microfluidics devices
    • Lin F, Saadi W, Rhee S W, Wang S-J, Mittal S, Jeon N L 2004 Generation of dynamic temporal and spatial concentration gradients using microfluidics devices. Lab Chip 4: 164-167.
    • (2004) Lab Chip , vol.4 , pp. 164-167
    • Lin, F.1    Saadi, W.2    Rhee, S.W.3    Wang, S.-J.4    Mittal, S.5    Jeon, N.L.6
  • 73
    • 3242670049 scopus 로고    scopus 로고
    • Electrophoresis microchips for DNA analysis
    • Liu S, Guttman A 2004 Electrophoresis microchips for DNA analysis. Trends Anal. Chem. 23: 422-431.
    • (2004) Trends Anal. Chem. , vol.23 , pp. 422-431
    • Liu, S.1    Guttman, A.2
  • 75
    • 33750580791 scopus 로고    scopus 로고
    • Modelling of transdermal drug delivery with a microneedle array
    • Lv Y-G, Liu J, Gao Y-H, Xu B 2006 Modelling of transdermal drug delivery with a microneedle array. J. Micromech. Microeng. 16: 2492-2501.
    • (2006) J. Micromech. Microeng. , vol.16 , pp. 2492-2501
    • Lv, Y.-G.1    Liu, J.2    Gao, Y.-H.3    Xu, B.4
  • 77
    • 0008328359 scopus 로고    scopus 로고
    • Flow characteristics of water in microtubes
    • Mala G M, Li D 1999 Flow characteristics of water in microtubes. Int. J. Heat Fluid Flow 20: 142-148.
    • (1999) Int. J. Heat Fluid Flow , vol.20 , pp. 142-148
    • Mala, G.M.1    Li, D.2
  • 78
    • 0037165671 scopus 로고    scopus 로고
    • A microfluidic device with a linear temperature gradient for parallel and combinatorial measurements
    • Mao H B, Yang T L, Cremer P S 2002 A microfluidic device with a linear temperature gradient for parallel and combinatorial measurements. J. Am. Chem. Soc. 124: 4432-4435.
    • (2002) J. Am. Chem. Soc. , vol.124 , pp. 4432-4435
    • Mao, H.B.1    Yang, T.L.2    Cremer, P.S.3
  • 79
    • 0344270926 scopus 로고    scopus 로고
    • Microfabricated needles for transdermal delivery of macromolecules and nanoparticles: Fabrication methods and transport studies
    • McAllister D V, Wang P M, Davis S P, Park J H, Canatella P J, Allen M G, Prausnitz M R 2003 Microfabricated needles for transdermal delivery of macromolecules and nanoparticles: Fabrication methods and transport studies. Proc. Natl Acad. Sci. 100: 13755-13760.
    • (2003) Proc. Natl Acad. Sci. , vol.100 , pp. 13755-13760
    • McAllister, D.V.1    Wang, P.M.2    Davis, S.P.3    Park, J.H.4    Canatella, P.J.5    Allen, M.G.6    Prausnitz, M.R.7
  • 81
    • 0035958596 scopus 로고    scopus 로고
    • Microfabricated capillary array electrophoresis DNA analysis systems
    • Medintz I L, Paegel B M, Mathies R A 2001 Microfabricated capillary array electrophoresis DNA analysis systems. J. Chromatography A924: 265-270.
    • (2001) J. Chromatography , vol.A924 , pp. 265-270
    • Medintz, I.L.1    Paegel, B.M.2    Mathies, R.A.3
  • 82
    • 0037102261 scopus 로고    scopus 로고
    • Mixing processes in a zigzag microchannel: Finite element simulations and optical study
    • Mengeaud V, Josserand J, Girault H H 2002 Mixing processes in a zigzag microchannel: Finite element simulations and optical study. Anal. Chem. 74: 4279-4286.
    • (2002) Anal. Chem. , vol.74 , pp. 4279-4286
    • Mengeaud, V.1    Josserand, J.2    Girault, H.H.3
  • 83
    • 0031249564 scopus 로고    scopus 로고
    • Rapid liver enzyme assay with miniaturized liquid handling system comprising thin film biosensor array
    • Moser I, Jobst G, Svasek P, Varahram M, Urban G 1997 Rapid liver enzyme assay with miniaturized liquid handling system comprising thin film biosensor array. Sens. Actuators B44: 377-80.
    • (1997) Sens. Actuators , vol.B44 , pp. 377-80
    • Moser, I.1    Jobst, G.2    Svasek, P.3    Varahram, M.4    Urban, G.5
  • 86
    • 0031903288 scopus 로고    scopus 로고
    • MAD phasing grows up
    • Ogata C M 1998 MAD phasing grows up. Nat. Struct. Biol. 5: 638-640.
    • (1998) Nat. Struct. Biol. , vol.5 , pp. 638-640
    • Ogata, C.M.1
  • 89
    • 12344272618 scopus 로고    scopus 로고
    • Integrated microelectrode array and microfluidics for temperature clamp of sensory neurons in culture
    • Pearce T M, Wilson J A, Oakes S G, Chiu S Y, Williams J C 2005 Integrated microelectrode array and microfluidics for temperature clamp of sensory neurons in culture. Lab Chip 5: 97-101.
    • (2005) Lab Chip , vol.5 , pp. 97-101
    • Pearce, T.M.1    Wilson, J.A.2    Oakes, S.G.3    Chiu, S.Y.4    Williams, J.C.5
  • 90
    • 0032964481 scopus 로고    scopus 로고
    • Automated protein model building combined with iterative structure refinement
    • Perrakis A, Morris R, Lamzin V S 1999 Automated protein model building combined with iterative structure refinement. Nat. Struct. Biol. 6: 458-463.
    • (1999) Nat. Struct. Biol. , vol.6 , pp. 458-463
    • Perrakis, A.1    Morris, R.2    Lamzin, V.S.3
  • 93
    • 0033024318 scopus 로고    scopus 로고
    • A single electrode conductivity detector for use in electrophoretic separation systems
    • Prest J E, Baldock S J, Bektas N, Fielden P R, Treves Brown B J 1999 A single electrode conductivity detector for use in electrophoretic separation systems. J. Chromatogr. A836: 59-65.
    • (1999) J. Chromatogr. , vol.A836 , pp. 59-65
    • Prest, J.E.1    Baldock, S.J.2    Bektas, N.3    Fielden, P.R.4    Treves Brown, B.J.5
  • 94
    • 0032538519 scopus 로고    scopus 로고
    • Exceeding 5000-fold concentration of dilute analytes in micellar electrokinetic chromatography
    • Quirino J P, Terabe S 1998 Exceeding 5000-fold concentration of dilute analytes in micellar electrokinetic chromatography. Science 285: 465-468.
    • (1998) Science , vol.285 , pp. 465-468
    • Quirino, J.P.1    Terabe, S.2
  • 97
    • 0028806048 scopus 로고
    • Quantitative monitoring of gene expression patterns with a complementary DNA microarray
    • Schena M, Shalon D, Davis R W, Brown P O 1995 Quantitative monitoring of gene expression patterns with a complementary DNA microarray. Science 270: 467-470.
    • (1995) Science , vol.270 , pp. 467-470
    • Schena, M.1    Shalon, D.2    Davis, R.W.3    Brown, P.O.4
  • 98
    • 0037090479 scopus 로고    scopus 로고
    • Cell lysis and protein extraction in a microfluidic device with detection by a fluorogenic enzyme assay
    • Schilling E A, Kamholz A E, Yager P 2002 Cell lysis and protein extraction in a microfluidic device with detection by a fluorogenic enzyme assay. Anal. Chem. 74: 1798-1804.
    • (2002) Anal. Chem. , vol.74 , pp. 1798-1804
    • Schilling, E.A.1    Kamholz, A.E.2    Yager, P.3
  • 99
    • 4043057432 scopus 로고    scopus 로고
    • An optimized split-and-recombine micromixer with uniform 'chaotic' mixing
    • Schönfeld F, Hessel V, Hofmann C 2004 An optimized split-and-recombine micromixer with uniform 'chaotic' mixing. Lab Chip 4: 65-6.
    • (2004) Lab Chip , vol.4 , pp. 65-6
    • Schönfeld, F.1    Hessel, V.2    Hofmann, C.3
  • 100
    • 15544383514 scopus 로고    scopus 로고
    • Mixing enhancement by using electrokinetic instability under time-periodic electric field
    • Shin S M, Kang I S, Cho Y K 2005 Mixing enhancement by using electrokinetic instability under time-periodic electric field. J. Micromech. Microeng. 15: 455-462.
    • (2005) J. Micromech. Microeng. , vol.15 , pp. 455-462
    • Shin, S.M.1    Kang, I.S.2    Cho, Y.K.3
  • 102
    • 24944498780 scopus 로고    scopus 로고
    • Microfluidics: Fluid physics at the nanoliter scale
    • Squires T M, Quake S R 2005 Microfluidics: Fluid physics at the nanoliter scale. Rev. Mod. Phys. 77: 977-1026.
    • (2005) Rev. Mod. Phys. , vol.77 , pp. 977-1026
    • Squires, T.M.1    Quake, S.R.2
  • 103
    • 3843065592 scopus 로고    scopus 로고
    • Mechanisms of DNA separation in entropic trap arrays: A Brownian dynamics simulation
    • Streek M, Schmid F, Duong T T, Ros A 2004 Mechanisms of DNA separation in entropic trap arrays: A Brownian dynamics simulation. J. Biotech. 112: 79-89.
    • (2004) J. Biotech. , vol.112 , pp. 79-89
    • Streek, M.1    Schmid, F.2    Duong, T.T.3    Ros, A.4
  • 105
    • 0037418472 scopus 로고    scopus 로고
    • Microfluidic multicomponent device for neuroscience research
    • Taylor A, Rhee S, Tu C, Cribbs D, Cotman C, Jeon N 2003 Microfluidic multicomponent device for neuroscience research. Langmuir 19: 1551-1556.
    • (2003) Langmuir , vol.19 , pp. 1551-1556
    • Taylor, A.1    Rhee, S.2    Tu, C.3    Cribbs, D.4    Cotman, C.5    Jeon, N.6
  • 106
    • 4544366400 scopus 로고    scopus 로고
    • Dynamic pattern formation in a vesiclegenerating microfluidic device
    • Thorsen T R, Roberts W, Arnold F H, Quake S R 2001 Dynamic pattern formation in a vesiclegenerating microfluidic device. Phys. Rev. Lett. 86: 4163-4166.
    • (2001) Phys. Rev. Lett. , vol.86 , pp. 4163-4166
    • Thorsen, T.R.1    Roberts, W.2    Arnold, F.H.3    Quake, S.R.4
  • 107
    • 0034002175 scopus 로고    scopus 로고
    • Single-strand conformation polymorphism analysis by capillary and microchip electrophoresis: A fast, simple method for detection of common mutations in BRCA1 and BRCA2
    • Tian H J, Jaquins-Gerstl A, Munro N, Trucco M, Brody L C, Landers J P 2000 Single-strand conformation polymorphism analysis by capillary and microchip electrophoresis: A fast, simple method for detection of common mutations in BRCA1 and BRCA2. Genomics 63: 25-34.
    • (2000) Genomics , vol.63 , pp. 25-34
    • Tian, H.J.1    Jaquins-Gerstl, A.2    Munro, N.3    Trucco, M.4    Brody, L.C.5    Landers, J.P.6
  • 108
    • 0034079719 scopus 로고    scopus 로고
    • Integration of a microextraction system on a glass chip: Ion-pair solvent extraction on Fe(II) with 4,7-Diphenyl-1,10-phenanthrolinedisulfonic acid and Tri-n-octylmethylammonium chloride
    • Tokeshi M, Minagawa T, Kitamori T 2000 Integration of a microextraction system on a glass chip: Ion-pair solvent extraction on Fe(II) with 4,7-Diphenyl-1,10-phenanthrolinedisulfonic acid and Tri-n-octylmethylammonium chloride. Anal. Chem. 72: 1711-1714.
    • (2000) Anal. Chem. , vol.72 , pp. 1711-1714
    • Tokeshi, M.1    Minagawa, T.2    Kitamori, T.3
  • 109
    • 0033138331 scopus 로고    scopus 로고
    • Characterization method for a new diffusion mixer applicable in microflow injection analysis systems
    • Veenstra T T, Lammerink T S J, Elwenspoek M C, vandenBerg A 1999 Characterization method for a new diffusion mixer applicable in microflow injection analysis systems. J. Micromech. Microeng. 9: 199-202.
    • (1999) J. Micromech. Microeng. , vol.9 , pp. 199-202
    • Veenstra, T.T.1    Lammerink, T.S.J.2    Elwenspoek, M.C.3    vandenBerg, A.4
  • 110
    • 0037102392 scopus 로고    scopus 로고
    • A microfabrication-based dynamic array cytometer
    • Voldman J, Gray M L, Toner M, Schmidt M A 2002 A microfabrication-based dynamic array cytometer. Anal. Chem. 74: 3984-3990.
    • (2002) Anal. Chem. , vol.74 , pp. 3984-3990
    • Voldman, J.1    Gray, M.L.2    Toner, M.3    Schmidt, M.A.4
  • 111
    • 20844440162 scopus 로고    scopus 로고
    • Effects of flow and diffusion on chemotaxis studies in a microfabricated gradient generator
    • Walker G M, Sai J, Richmond A, Stremler M, Chung C Y, Wikswo J P 2005 Effects of flow and diffusion on chemotaxis studies in a microfabricated gradient generator. Lab Chip 5: 611-618.
    • (2005) Lab Chip , vol.5 , pp. 611-618
    • Walker, G.M.1    Sai, J.2    Richmond, A.3    Stremler, M.4    Chung, C.Y.5    Wikswo, J.P.6
  • 112
    • 0037355342 scopus 로고    scopus 로고
    • Microarrays assembled in microfluidic chips fabricated from poly(methyl methacrylate) for the detection of low-abundant DNA mutations
    • Wang Y, Vaidya B, Farquar H D, Stryjewski W, Hammer R P, Mccarley R L, Soper S A 2003 Microarrays assembled in microfluidic chips fabricated from poly(methyl methacrylate) for the detection of low-abundant DNA mutations. Anal. Chem. 75: 1130-1140.
    • (2003) Anal. Chem. , vol.75 , pp. 1130-1140
    • Wang, Y.1    Vaidya, B.2    Farquar, H.D.3    Stryjewski, W.4    Hammer, R.P.5    Mccarley, R.L.6    Soper, S.A.7
  • 113
    • 0343819793 scopus 로고    scopus 로고
    • Pressure-driven water flows in trapezoidal silicon microchannels
    • Weilin Q, Mala G M, Li D 2000 Pressure-driven water flows in trapezoidal silicon microchannels. Int. J. Heat Mass Transfer 43: 353-364.
    • (2000) Int. J. Heat Mass Transfer , vol.43 , pp. 353-364
    • Weilin, Q.1    Mala, G.M.2    Li, D.3
  • 116
    • 0029989857 scopus 로고    scopus 로고
    • Functional integration of PCR amplification and capillary electrophoresis in a microfabricatedDNAanalysis device
    • Woolley T, Hadley D, Landre P, deMello A J, Mathies R A, Northrup M A 1996 Functional integration of PCR amplification and capillary electrophoresis in a microfabricatedDNAanalysis device. Anal. Chem. 68: 4081-4086.
    • (1996) Anal. Chem. , vol.68 , pp. 4081-4086
    • Woolley, T.1    Hadley, D.2    Landre, P.3    deMello, A.J.4    Mathies, R.A.5    Northrup, M.A.6
  • 117
    • 23644448617 scopus 로고    scopus 로고
    • Development of a microfluidic biosensor module for pathogen detection
    • Zaytseva N V, Goral V N, Montagna R A, Baeumner A J 2005 Development of a microfluidic biosensor module for pathogen detection. Lab Chip 5: 805-811.
    • (2005) Lab Chip , vol.5 , pp. 805-811
    • Zaytseva, N.V.1    Goral, V.N.2    Montagna, R.A.3    Baeumner, A.J.4
  • 118
    • 4344691618 scopus 로고    scopus 로고
    • Multi-analyte single-membrane biosensor for the serotype-specific detection of Dengue virus
    • Zaytseva N V, Montagna R A, Lee E M, Baeumner A J 2004 Multi-analyte single-membrane biosensor for the serotype-specific detection of Dengue virus. Anal. Bioanal. Chem. 380: 46-53.
    • (2004) Anal. Bioanal. Chem. , vol.380 , pp. 46-53
    • Zaytseva, N.V.1    Montagna, R.A.2    Lee, E.M.3    Baeumner, A.J.4
  • 119
    • 0035135971 scopus 로고    scopus 로고
    • Surface-directed liquid flow inside microchannels
    • Zhao B, Moore J S, Beebe D J 2001 Surface-directed liquid flow inside microchannels. Science 291: 1023-1026.
    • (2001) Science , vol.291 , pp. 1023-1026
    • Zhao, B.1    Moore, J.S.2    Beebe, D.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.