Isoalantolactone from inula helenium caused nrf2-mediated induction of detoxifying enzymes

Journal of Medicinal Food

Volumn 12, Issue 5, 2009, Pages 1038-1045

  Seo, Ji Yeon ^a   Park, Jia ^a   Kim, Hyo Jung ^a   Lee, In Ae ^a   Lim, Ji Sun ^a   Lim, Soon Sung ^b   Choi, Se Jin ^b   Park, Jung Han Yoon ^b   Kang, Hui Jung ^c   Kim, Jong Sang ^a  

^a Kyungpook National University   (South Korea)

^b Hallym University   (South Korea)

^c Kyungsung University   (South Korea)

Author keywords

Akt; Antioxidant response element; Chemoprevention; Detoxifying enzymes; Isoalantolactone; NAD(P)H:(quinone acceptor) oxidoreductase 1; Nuclear factor E2 related factor 2; Phosphatidylinositol 3 kinase; Sesquiterpenes

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ALANTOLACTONE; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE REDUCTASE; HEME OXYGENASE 1; HYPOXIA INDUCIBLE FACTOR 1BETA; ISOALANTOLACTONE; LUCIFERASE; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; WORTMANNIN;

ANIMAL CELL; ANTIOXIDANT RESPONSIVE ELEMENT; ARTICLE; CELL ASSAY; CELL CULTURE; CELL MUTANT; CHEMOPROPHYLAXIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; DETOXIFICATION; DRUG EXPOSURE; DRUG STRUCTURE; ELECAMPANE; ENZYME ACTIVITY; ENZYME INDUCTION; HUMAN; HUMAN CELL; MEDICINAL PLANT; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYMES; FRUIT; HEP G2 CELLS; HUMANS; INULA; LIVER NEOPLASMS; METABOLIC DETOXICATION, DRUG; MICE; NAD(P)H DEHYDROGENASE (QUINONE); NF-E2-RELATED FACTOR 2; PHYTOTHERAPY; PLANT EXTRACTS; PLANT ROOTS; SESQUITERPENES;

INULA HELENIUM;

EID: 70350519605     PISSN: 1096620X     EISSN: None     Source Type: Journal    
DOI: 10.1089/jmf.2009.0072     Document Type: Article

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