Polyozellin Isolated from Polyozellus multiplex Induces Phase 2 Enzymes in Mouse Hepatoma Cells and Differentiation in Human Myeloid Leukaemic Cell Lines

Journal of Agricultural and Food Chemistry

Volumn 52, Issue 3, 2004, Pages 451-455

  Kim, Jeong Hyun ^a   Lee, Jeong Soon ^a   Song, Kyung Sik ^a   Kwon, Chong Suk ^b   Kim, Young Kyoon ^c   Kim, Jong Sang ^a  

^a Kyungpook National University   (South Korea)

^b Andong National University   (South Korea)

^c Kookmin University   (South Korea)

Author keywords

Cancer prevention; Glutathione S transferase; Polyozellin; Quinone reductase

Indexed keywords

ANTINEOPLASTIC AGENT; ENZYME; FURAN DERIVATIVE; GLUTATHIONE; GLUTATHIONE TRANSFERASE; METHANOL; PLANT EXTRACT; POLYOZELLIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); UNCLASSIFIED DRUG;

AGARICALES; ANIMAL; ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BIOASSAY; BIOSYNTHESIS; CANCER PREVENTION; CELL CULTURE; CELL DIFFERENTIATION; CHEMISTRY; CYTOMETRY; DOSE RESPONSE; DRUG EFFECT; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYMOLOGY; FRACTIONATION; HEPATOMA CELL; HUMAN; HUMAN CELL; ISOLATION AND PURIFICATION; LIVER TUMOR; MOUSE; MUSHROOM; MYELOID LEUKEMIA; NONHUMAN; PATHOLOGY; POLYOZELLUS MULTIPLEX; PROMYELOCYTIC LEUKEMIA;

AGARICALES; ANIMALIA; BASIDIOMYCOTA; MAMMALIA; MURINAE;

EID: 0842263125     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf034748n     Document Type: Article

References (21)

1. Prestera, T.; Holtzclaw, W. D.; Zhang, Y. S.; Talalay, P. Chemical and molecular regulation of enzymes that detoxify carcinogens. Proc. Natl. Acad. Sci. U.S.A. 1993, 90, 2965-2969.
2. De Long, M. J.; Prochaska, H. J.; Talalay, P. Induction of NAD(P)H/quinone reductase in murine hepatoma cells by phenolic antioxidants, azo dyes, and other chemoprotectors: A model system for the study of anticarcinogens. Proc. Natl. Acad. Sci. U.S.A. 1986, 83, 787-791.
3. Ross, D.; Kepa, J. K.; Winski, S. L.; Beall, H. D.; Anwar, A.; Siegel, D. NAD(P)H/quinone oxidoreductase 1 (NQO1): chemoprotection, bioactivation, gene regulation, and genetic polymorphisms. Chem. Biol. Interact. 2000, 129, 77-97.
4. Alexander, H. S.; Elizabeth, E. M. The genus cantharellus in the western United States. Mycologia 1947, 39, 497-534.
5. Haward, E. B. The cantharelloid fungi of new England and adjacent areas. Mycologia 1978, 70, 707-756.
6. Benson, A. M.; Hunkeler, M. J.; Talalay, P. Increase of NAD(P)H/quinone reductase by dietary antioxdants; Possible role in protection against carcinogenesis and toxicity. Proc. Natl. Acad. Sci. U.S.A. 1980, 77, 5216-5220.
7. Habig, W. H.; Pabst, M. J.; Jakoby, W. B. Glutathione S-transferases. The first enzymatic step in mercapturic acid formation. J. Biol. Chem. 1974, 249, 7130-7139.
8. Anderson, M. E. Determination of glutathione and glutathione disulfide in biological samples. Methods Enzymol. 1985, 113, 548-555.
9. Short protocols in molecular biology, 4th ed.; Ausbel, F. M., Brent, R., Kingston, R. E., Moore, D. D., Seidman, J. G., Smith, J. A., Struhl, K., Eds.; Johns & Sons: New York, 1999; pp 10-40-10-48.
10. Suh, N.; Luyengi, L.; Fong, H. H.; Kinghorn, A. D.; Pezzuto, J. M. Discovery of natural product chemopreventive agents utilizing HL-60 cell differentiation as a model. Anticancer Res. 1995, 15, 233-239.
11. Kwak, J.-Y.; Rhee, I.-K.; Lee, K.-B.; Hwang, J.-S.; Yoo, I.-D.; Song, K.-S. Thelephoric acid and Kynapcin-9 in mushroom Polyozellus multiflex inhibit prolyl endopeptidase in vitro. J. Microbiol. Biotechnol. 1999, 9, 798-803.
12. Hwang, J.-S.; Song, K.-S.; Kim, W.-G.; Lee, T.-H.; Koshino, H.; Yoo, I.-D. Polyozellin, a new inhibitor of prolyl endopeptidase from Polyozellus multiflex. J. Antibiotics 1997, 50, 773-777.
13. Kim, H.-J.; Han, J.; Yang, E. J.; Lee, K.-R.; Lee, I.-S. Chemoprevention effect of Polyozellus multiplex, a wild and edible mushroom. J. Korean Soc. Food Sci. Nutr. 2000, 29, 161-167.
14. Prochaska, H. Screening strategies for the detection of anticarcinogenic enzyme inducers. J. Nutr. Biochem. 1994, 5, 360-368.
15. Jiang, Z. Q.; Chen, C.; Yang, B.; Hebbar, V.; Kong, A. N. Differential responses from seven mammalian cell lines to the treatments of detoxifying enzyme inducers. Life Sci. 2003, 72, 2243-2253.
16. Steele, V. E.; Kelloff, G. J.; Balentine, D.; Boone, C. W.; Mehta, R.; Bagheri, D.; Sigman, C. C.; Zhu, S.; Sharma, S. Comparative chemopreventive mechanisms of green tea, black tea, and selected polyphenol extracts measured by in vitro bioassays. Carcinogenesis 2000, 21, 63-67.
17. Song, L. L.; Kosmeder, J. W., 2nd; Lee, S. K.; Gerhauser, C.; Lantvit, D.; Moon, R. C.; Moriarty, R. M.; Pezzuto, J. M. Cancer chemopreventive activity mediated by 4′-bromoflavone, a potent inducer of phase II detoxification enzymes. Cancer Res. 1999, 59, 578-585.
18. Kwon, C. S.; Kim, J. H.; Son, K. H.; Kim, Y. K.; Lee, J. S.; Lim, J. K.; Kim, J.-S. Induction of quinone reductase, an anticarcinogenic marker enzyme, by medicinal herb extracts. Neutraceuticals Food 2002, 7, 358-366.
19. Kim, S. M.; Ryu, S. H.; Choi, H. D.; Kim, S. S.; Kim, J. H.; Kim, J.-S. Screening for korean vegetables with anticarcinogenic enzyme inducing activity using cell culture system. J. Food Sci. Nutr. 1998, 3, 277-281.
20. Zhang, J. X.; Fong, W. F.; Wu, J. Y.; Yang, M.; Cheung, H. Y.; Pyranocoumarins isolated from Peucedanum praeruptorum as differentiation inducers in human leukemic HL-60 cells. Planta Med. 2003, 69, 223-229.
21. Song, K. S.; Raskin, I. A prolyl endopeptidase-inhibiting benzofuran dimer from Polyozellus multiflex. J. Nat. Prod. 2002, 65, 76-78.