Differential gene expression in wild-type and Arnt-defective mouse hepatoma (Hepa1c1c7) cells

Toxicological Sciences

Volumn 52, Issue 2, 1999, Pages 217-225

  Seidel, Shawn D ^a   Denison, Michael S ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Ah receptor; Arnt; Differential display; PAS; Serpin; Steel factor; WW domain binding protein

Indexed keywords

AROMATIC HYDROCARBON RECEPTOR; BINDING PROTEIN; HELIX LOOP HELIX PROTEIN; SERINE PROTEINASE INHIBITOR; STEEL FACTOR;

ANIMAL CELL; ARTICLE; CELL CLONE; GENE EXPRESSION; LIVER CELL CARCINOMA; NONHUMAN; PERIODIC ACID SCHIFF STAIN; PLASMID; PROTEIN BINDING;

EID: 0033375227     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/52.2.217     Document Type: Article

References (39)

1. Altschul, S. F., Gish, W., Miller, W., Myers, E. W., and Lipman D. J. (1990). Basic local alignment search tool. J. Mol. Biol. 215, 403-410.
2. Anderson, D. M., Lyman, S. D., Baird, A., Wignall, J. M., Eisenman, J., Rauch, C., March, C. J., Boswell, H. S., Gimpel, S. D., Cosman, D., and Williams, D. E. (1990).Molecular cloning of mast-cell growth factor, a hematopoietin that is active in both membrane-bound and soluble forms. Cell 63, 235-243.
3. Bedell, M. S., Copeland, N. G., and Jenkins, N. A. (1996). Multiple pathways for Steel regulation suggested by genomic and sequence analysis of the murine Steel gene. Genetics 142, 927-934.
4. Bedford, M. T., Chan, D. C., and Leder P. (1997). FBP WW domains and the AbI SH3 domain bind to a specific class of proline-rich ligands. EMBO J. 16, 2376-2383.
5. Denison, M. S., and Deal, R. M. (1990). The binding of transformed aromatic hydrocarbon (Ah) receptor to its DNA recognition site is not affected by metal depletion. Mol. Cell Endocrinol. 69, 51-57.
6. Denison, M. S., Fisher, J. M., and Whitlock, J. P., Jr. (1988). The DNA recognition site for the dioxin-Ah receptor complex: nucleotide sequence and functional analysis. J. Biol. Chem. 263, 17221-17224.
7. Denison, M. S., Vella, L. M., and Okey, A. B. (1986). Structure and function of the Ah receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin: Species difference in molecular properties of the receptors from mouse and rat hepatic cytosols. J. Biol. Chem. 261, 3987-3995.
8. Fisher, J. M., Wu, L., Denison, M. S., and Whitlock, J. P., Jr. (1990). Organization and function of a dioxin-responsive enhancer. J. Biol. Chem. 265, 9676-9681.
9. Flanagan, J. G., and Leder P. (1990). The kit ligand: A cell surface molecule altered in Steel mutant fibroblasts. Cell 63, 185-194.
10. Garrison, P. M., Tullis, K., Aarts, J. M. M. J. G., Brouwer, A., Giesy, J. P., and Denison, M. S. (1996). Species-specific recombinant cell lines as bioassay systems for the detection of 2,3,7,8-tetrachlorodibenzo-p-dioxin-like chemicals. Fundam. Appl. Toxicol. 30, 194-203.
11. Gassmann, M., Kvietikova, I., Rolfs, A., and Wenger, R. H. (1997). Oxygen-and dioxin-regulated gene expression in mouse hepatoma cells. Kidney Intern 51, 567-574.
12. Hankinson, O. (1980) Mutant of cultured hepatoma cells deficient in aryl hydrocarbon hydroxylase, in Microsomes, Drug Oxidations, and Chemical Carcinogenesis (Conney AH, Coon MJ, Estabrook RW, Gelboin HV, Gillette JR, and O'Brien RJ, eds.) pp 1149-1152. Academic Press, New York.
13. Hankinson, O. (1981) Evidence that benzo(a)pyrene-resistant, aryl hydrocarbon hydroxylase-deficient variants of mouse hepatoma line, Hepa-1, are mutational in origin. Somatic Cell Genet. 7, 373-388.
14. Hankinson, O. (1995). The aryl hydrocarbon receptor complex. Annu. Rev. Pharmacol. Toxicol. 35, 307-340.
15. Hoffman, E. C., Reyes, H., Chu, F.-F., Sander, F., Conley, L. H., Brooks, B. A., and Hankinson, O. (1991) Cloning of a factor required for activity of the Ah (dioxin) receptor. Science 252, 954-958.
16. Huang, E., Nocka, K., Beier, D. R., Chu, T.-Y., Buck, J., Lahm, H. W., Wellner, D. Leder, P., and Besmer P. (1990). The hematopoietic growth factor KL is encoded by the Sl locus and is the ligand of the c-kit receptor, the gene product of the W locus. Cell 63, 225-233.
17. Kawai, S., and Nishizawa, M. (1984). New procedure for DNA transfection with polycation and dimethyl sulfoxide. Mol. Cell. Biol. 4, 1172-1174.
18. Kordula, T., Dubin, A., Schooltink, H., Koj, A., Heinrich, P. C., and Rose-John, S. (1993). Molecular cloning and expression of an intracellular serpin: an elastase inhibitor from horse leucoytes. Biochem. J. 293, 187-193.
19. Kozak, K. R., Abbott, B., and Hankinson, O. (1997). ARNT-deficient mice and placental differentiation. Dev. Biol. 191, 297-305.
20. Liang, P., and Pardee, A. B. (1992). Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction. Science 257, 967-971.
21. Lorenzen, A., and Kennedy, S. W. (1993). A fluorescence-based protein assay for use with a microplate reader. Anal. Biochem. 214, 346-348.
22. Ma, Q., and Whitlock, J. P., Jr. (1996). The aromatic hydrocarbon receptor modulates the Hepa 1c1c7 cell cycle and differentiated state independently of dioxin. Mol. Cell Biol. 16, 2144-2150.
23. Maltepe, E., Schmidt, J., Baunoch, D., Bradfield, C., and Simon, M. (1997). Abnormal angiogenesis and responses to glucose and oxygen deprivation in mice lacking the protein ARNT. Nature 386, 403-407.
24. Miller, A. G., Israel, D., and Whitlock, J. P., Jr. (1983). Biochemical and genetic analysis of variant mouse hepatoma cells defective in the induction of benzo(a)pyrene-metabolizing enzyme activity. J. Biol. Chem. 258, 3523-3527.
25. Miller, A. G., and Whitlock, J. P., Jr. (1981). Novel variants in benzo(a)pyrene metabolism: isolation by fluorescence-activated cell sorting. J. Biol. Chem. 256, 2433-2437.
26. Numayama-Tsuruta, K., Kobayashi, A., Sogawa, K., and Fujii-Kuriyama, Y. (1997). A point mutation responsible for defective function of the aryl-hydrocarbon-receptor nuclear translocator in mutant Hepa-1c1c7 cells. Eur. J. Biochem. 246, 486-495.
27. Pollenz, R. S., Sattler, C. A., and Poland, A. (1993). The aryl hydrocarbon receptor and aryl hydrocarbon receptor nuclear translocator protein show distinct subcellular localizations in Hepa1c1c7 cells by immunofluorescence microscopy. Molec. Pharmacol. 45, 428-438.
28. Puga, A., Nebert, D. W., and Carrier, F. (1992). Dioxin induces expression of c-fos and c-jun proto-oncogenes and a large increase in transcription factor AP-1. DNA Cell Biol. 11, 269-281.
29. Remold-O'Donnell, E., Chin, J., and Alberts, M. (1992). Sequence and molecular characterization of human monocyte/neutrophil elastase inhibitor. Proc. Natl. Acad. Sci. U S A 89, 5635-5639.
30. Reisz-Porszasz, S., Probst, M., Fukunaga, B. N., and Hankinson, O. (1994). Identificatino of functional domains of the aryl hydrocarbon receptor nuclear translocator protein (ARNT), Mol. Cell. Biol. 14, 6075-6086.
31. Reyes, H., Reisz-Porszasz, S. and Hankinson, O. (1992) Identification of the Ah receptor nuclear translocator protein (Amt) as a component of the DNA binding form of the Ah receptor. Science 256:1193-1195.
32. Rowlands, J. C., and Gustafsson, J.-A. (1997). Aryl hydrocarbon receptor-mediated signal transduction. CRC Crit. Rev. Toxicol. 27, 109-134.
33. Sadek, C. M., and Allen-Hoffmann, B. L. (1994). Suspension-mediated induction of Hepa 1c1c7 cypla-1 expression is dependent on the Ah receptor signal-transduction pathway. J. Biol. Chem. 269, 1505-31509.
34. Semenza, G. L., Roth, P. H., Fang, H.-M., and Wang, G. L. (1994). Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1. J. Biol. Chem. 269, 23757-23763.
35. Sudol, M. (1996). Structure and function of the WW domain. Prog. Biophys. Mol. Biol. 65, 113-132.
36. Weiss, C., Kolluri, S. K., Kiefer, F., and Gottlicher, M. (1996). Complementation of Ah receptor deficiency in hepatoma cells: Negative feedback regulation and cell cycle control by the Ah receptor. Exp. Cell. Res. 226, 154-63.
37. Whitlock, J. P., Jr., Okino, S., Dong, L., Ko, H., Clarke-Katzenberg, R., Ma, Q., and Li, H. (1996). Cytochromes P450 5: Induction of cytochrome P4501A1: A model for analyzing mammalian gene transcription. FASEB J. 10, 809-818.
38. Wood, S., Gleadle, J., Pugh, C., Hankinson, O., and Ratcliffe, P. (1996). The role of the aryl hydrocarbon receptor nuclear translocator (ARNT) in hypoxic induction of gene expression. J. Biol. Chem. 271, 15117-15123.
39. Zsebo, K. M., Williams, D. A., Geissler, E. N., Broudy, V. C., Martin, F. H., Atkins, H. L., Hsu, R.-Y., Birkett, N. C., Okino, K. H., Murdock, D. C., Jacobsen, F. W., Langley, K. E., Smith, K. A., Takeishi, T., Cattanach, S. M., Galli, S. J. and Suggs, S. V. (1990) Stem cell factor is encoded at the Sl locus of the mouse and is the ligand for the c-kit tyrosine kinase receptor. Cell 63, 213-224.