Residues at P2-P1 positions of e{open}- and ζ-cleavage sites are important in formation of β-amyloid peptide

Neurobiology of Disease

Volumn 36, Issue 3, 2009, Pages 453-460

  Tan, Jianxin ^a   Mao, Guozhang ^a   Cui, Mei Zhen ^a   Lamb, Bruce ^b   Sy, Man Sun ^c   Xu, Xuemin ^a  

^a UNIVERSITY OF TENNESSEE   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c LERNER RESEARCH INSTITUTE   (United States)

Author keywords

amyloid; secretase; Alzheimer's disease; APP; Intramembrane processing

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; AROMATIC AMINO ACID; GAMMA SECRETASE; PRESENILIN 1; PRESENILIN 2;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DISEASE COURSE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; GENE MUTATION; MOUSE; NERVE CELL; NEUROMODULATION; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN LOCALIZATION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE;

AMINO ACID SEQUENCE; AMYLOID BETA-PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; BLOTTING, WESTERN; CELL LINE; CELL LINE, TUMOR; GLYCINE; HUMANS; IMMUNOPRECIPITATION; MICE; MICE, KNOCKOUT; MUTATION; PHENYLALANINE; RECEPTORS, CELL SURFACE; THREONINE; TRANSFECTION;

EID: 70350342277     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2009.08.010     Document Type: Article

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