Proteases and antiproteases in chronic neutrophilic lung disease - Relevance to drug discovery

British Journal of Pharmacology

Volumn 158, Issue 4, 2009, Pages 1048-1058

  Greene, Catherine M ^a   McElvaney, Noel G ^a  

^a BEAUMONT HOSPITAL   (Ireland)

Author keywords

Alpha 1 antitrypsin; Antiprotease; Chronic obstructive pulmonary disease (COPD); Cystic fibrosis; Elafin; Lung; Neutrophil elastase; Protease; Secretory leucoprotease inhibitor

Indexed keywords

ALPHA 1 ANTITRYPSIN; BACTERIAL ENZYME; CATHELICIDIN; CATHELICIDIN ANTIMICROBIAL PEPTIDE LL 37; DEFENSIN; ELAFIN; INTERLEUKIN 8; LACTOFERRIN; LEUKOCYTE ELASTASE; LEUKOCYTE ELASTASE INHIBITOR; LYSOZYME; METALLOPROTEINASE; MUCIN; PEPTIDE CHLOROMETHYL KETONE; PROTEINASE; PROTEINASE INHIBITOR; SECRETORY LEUCOPROTEASE INHIBITOR; TISSUE INHIBITOR OF METALLOPROTEINASE; UNCLASSIFIED DRUG;

BACTERIAL PNEUMONIA; BACTERICIDAL ACTIVITY; CHRONIC INFLAMMATORY LUNG DISEASE; CHRONIC LUNG DISEASE; CYTOKINE PRODUCTION; ENZYME ACTIVITY; HUMAN; LUNG EMPHYSEMA; LUNG FIBROSIS; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PNEUMONIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PSEUDOMONAS INFECTION; REVIEW;

ANIMALS; CHRONIC DISEASE; DRUG DISCOVERY; HUMANS; LUNG DISEASES; PEPTIDE HYDROLASES; PROTEASE INHIBITORS;

EID: 70350130097     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2009.00448.x     Document Type: Review

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