Elafin (elastase-specific inhibitor) has anti-microbial activity against Gram-positive and Gram-negative respiratory pathogens

FEBS Letters

Volumn 452, Issue 3, 1999, Pages 309-313

  Simpson, A J ^a   Maxwell, A I ^a   Govan, J R W ^a   Haslett, C ^a   Sallenave, J M ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Anti microbial activity; Elafin; Human neutrophil elastase; Pseudomonas aeruginosa; Staphylococcus aureus

Indexed keywords

ELAFIN; ELASTASE INHIBITOR;

ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERICIDAL ACTIVITY; CONTROLLED STUDY; MOLECULAR WEIGHT; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS;

ANTIFUNGAL AGENTS; GRAM-NEGATIVE BACTERIA; GRAM-POSITIVE BACTERIA; HUMANS; KINETICS; MICROBIAL SENSITIVITY TESTS; PANCREATIC ELASTASE; PEPTIDE FRAGMENTS; PROTEINASE INHIBITORY PROTEINS, SECRETORY; PROTEINS; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS; RESPIRATORY TRACT INFECTIONS; SERINE PROTEINASE INHIBITORS; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS;

BACTERIA (MICROORGANISMS); NEGIBACTERIA; POSIBACTERIA; PSEUDOMONAS; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS;

EID: 0033003889     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(99)00670-5     Document Type: Article

References (43)

1. Ganz T., Selsted M.E., Lehrer R.I. Semin. Respir. Inf. 1:1986;107-117.
2. Coonrad J.D. Semin. Respir. Inf. 1:1986;118-129.
3. Ganz T., Selsted M.E., Szkiarek D., Harwig S.L., Daher K. J. Clin. Invest. 76:1985;1427-1435.
4. Goldman M.J., Anderson G.M., Stolzenberg E.D., Kari U.P., Zasloff M., Wilson J.M. Cell. 88:1997;553-560.
5. Hiemstra P.S., Maassen R.J., Stolk J., Heinzel-Wieland R., Steffens G.J., Dijkman J.H. Infect. Immun. 64:1996;4520-4524.
6. Bals R., Wang X., Zasloff M., Wilson J.M. Proc. Natl. Acad. Sci. USA. 95:1998;9541-9546.
7. Weiss S.J. NEJM. 320:1989;365-376.
8. Gadek J.E., Fells G.A., Zimmerman R.L., Rennard S.I., Crystal R.G. J. Clin. Invest. 68:1981;889-898.
9. Sallenave J.-M. Biol. Chem. Hoppe-Seyler. 372:1991;13-21.
10. Sallenave J.-M., Silva A., Marsden M.E., Ryle A.P. Am. J. Respir. Cell Mol. Biol. 8:1993;126-133.
11. Kramps J.A., Willems L.N.A., Franken C., Dijkman J.H. Biol. Chem. Hoppe-Seyler. 369:1988;83-87.
12. Sallenave, J.-M., Morgan, K., Gauldie, J. and Kalsheker, N. (1999) in: Molecular Biology of the Lung. Emphysema and Infection (Stockley, R.A., Ed.), Vol.1, pp. 69-94, Birkhäuser Verlag, Basel.
13. Sallenave J.-M., Silva A. Am. J. Respir. Cell Mol. Biol. 8:1993;439-445.
14. Wiedow O., Schröder J., Gregory H., Young J.A., Christophers E. J. Biol. Chem. 265:1990;14791-14795.
15. Nara K., Ito S., Ito T., Suzuki Y., Ghoneim M.A., Tachibana S., Hirose S. J. Biochem. 115:1994;441-448.
16. Wiedow O., Harder J., Bartels J., Streit V., Christophers E. Biochem. Biophys. Res. Commun. 248:1998;904-909.
17. Tsunemi M., Matsuura Y., Sakakibara S., Katsube Y. Biochemistry. 35:1996;11570-11576.
18. Rello J., Rue M., Jubert P., Muses G., Sonora R., Valles J., Niederman M.S. Crit. Care Med. 25:1997;1862-1867.
19. Govan J.R.W., Nelson J.W. Br. Med. Bull. 48:1992;912-930.
20. Govan J.R.W., Deretic V. Microbiol. Rev. 60:1996;539-574.
21. Lowy F.D. NEJM. 339:1998;520-532.
22. Hancock R.E. Clin. Infect. Dis. 27:1998;S93-S99.
23. Waldvogel F.A. NEJM. 340:1999;556-557.
24. Morrison G.M., Davidson D.J., Kilanowski F.M., Borthwick D.W., Crook K., Maxwell A.I., Govan J.R.W., Dorin J.R. Mamm. Genome. 9:1998;453-457.
25. Grütter M.G., Fendrich G., Huber R., Bode W. EMBO J. 7:1988;345-351.
26. Sallenave J-M., Xing Z., Simpson A.J., Graham F.L., Gauldie J. Gene Ther. 5:1998;352-360.
27. Bieth J.G. Bull. Eur. Physiopathol. Respir. 16:1980;183-195.
28. Sallenave, J.-M., Donnelly, S.C., Grant, I.S., Robertson, C., Gauldie, J. and Haslett, C. (1999) Eur. Respir. J. (in press).
29. McNeely T.B., Dealy M., Dripps D.J., Orenstein J.M., Eisenberg S.P., Wahl S.M. J. Clin. Invest. 96:1995;456-464.
30. Jin F.-Y., Nathan C., Radzioch D., Ding A. Cell. 88:1997;417-426.
31. Zhang Y., DeWitt D.L., McNeely T.B., Wahl S.M., Wahl L.M. J. Clin. Invest. 99:1997;894-900.
32. Molhuizen H.O.F., Schalkwijk J. Biol. Chem. Hoppe-Seyler. 376:1995;1-7.
33. Tsunemi M., Kato H., Nishiuchi Y., Kumagaye S., Sakakibara S. Biochem. Biophys. Res. Commun. 185:1992;967-973.
34. Juffs H.S. J. Appl. Bacteriol. 40:1976;23-32.
35. Peterson A.A., Hancock R.E.W., McGroarty E.J. J. Bacteriol. 164:1985;1256-1261.
36. Davis P.B., Drumm M., Konstan M.W. Am. J. Respir. Crit. Care Med. 154:1996;1229-1256.
37. Wilson R., Dowling R.B. Thorax. 53:1998;213-219.
38. Niederman M.S., Merrill W.W., Polomski L.M., Reynolds H.Y., Gee J.B. Am. Rev. Respir. Dis. 133:1986;255-260.
39. Melby K., Toews G.B., Pierce A.K. Am. Rev. Respir. Dis. 131:1985;559-563.
40. Sallenave J.-M., Kirpalani H., Mistry R., Sabry M., Cox G., Wilson W., Newhouse M., Tetley T., Jordana M., Gauldie J. Am. J. Respir. Crit. Care Med. 151:1995;A531.
41. Simpson, A.J., Porteous, D.J., Haslett, C. and Sallenave, J.-M. (1999) Am. J. Respir. Crit. Care Med. (in press).
42. Kolls J.K., Lei D., Nelson S., Summer W.R., Shellito J.E. Chest. 111:1997;104S.
43. Kolls J.K., Habetz S., Shean M.K., Vazquez C., Brown J.A., Lei D., Schwarzenberger P., Ye P., Nelson S., Summer W.R., Shellito J.E. J. Immunol. 162:1999;2890-2894.