Antibacterial activity of antileukoprotease

Infection and Immunity

Volumn 64, Issue 11, 1996, Pages 4520-4524

  Hiemstra, P S ^a   Maassen, R J ^a   Stolk, J ^a   Heinzel Wieland, R ^b   Steffens, G J ^b   Dijkman, J H ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b GRÜNENTHAL GMBH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEINASE INHIBITOR;

ANTIBACTERIAL ACTIVITY; ARTICLE; ENZYME INHIBITION; ESCHERICHIA COLI; HOST RESISTANCE; HUMAN; HUMAN CELL; INFECTION RESISTANCE; PRIORITY JOURNAL; STAPHYLOCOCCUS AUREUS;

EID: 0029969053     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.64.11.4520-4524.1996     Document Type: Article

References (39)

1. Bieth, J. G. 1984. In vivo significance of kinetic constants of protein proteinase inhibitors. Biochem. Med. 32:387-397.
2. Björck, L., P. Åkesson, M. Bohus, J. Trojnar, M. Abrahamson, I. Olafsson, and A. Grubb. 1989. Bacterial growth blocked by a synthetic peptide based on the structure of a human proteinase inhibitor. Nature (London) 337:385-386.
3. Couto, M. A., S. S. L. Harwig, J. S. Cullor, J. P. Hughes, and R. I. Lehrer. 1992. cNAP-2, a novel cysteine-rich bactericidal peptide from equine leukocytes. Infect. Immun. 60:5042-5047.
4. Couto, M. A., S. S. L. Harwig, and R. I. Lehrer. 1993. Selective inhibition of microbial serine protcases by eNAP-2, an antimicrobial peptide from equine neutrophils. Infect. Immun. 61:2991-2994.
5. Diamond, G., M. Zasloff, H. Eck, M. Brasseur, W. L. Malov, and C. L. Bevins. 1991. Tracheal antimicrobial peptide, a cysteine-rich peptide from mammalian tracheal mucosa: peptide isolation and cloning of a cDNA. Proc. Natl. Acad. Sci. USA 88:3952-3956.
6. Drenth, J., B. W. Low, J. S. Richardson, and C. S. Wright. 1980. The toxin-agglutinin fold. A new group of small protein structures organized around a four-disulfide core. J. Biol. Chem. 255:2652-2655.
7. Eisenberg, S. P., K. K. Hale, P. Heimdal, and R. C. Thompson. 1990. Location of the protease-inhibitory region of secretory leukocyte protease inhibitor. J. Biol. Chem. 265:7976-7981.
8. Feinstein, G., and A. Janoff. 1975. A rapid method of purification of human granulocyte cationic neutral proteases: purification and further characterization of human granulocyte elastase. Biochim. Biophys. Acta 403:493-505.
9. Franken, C., C. J. L. M. Meijer, and J. H. Dijkman. 1989. Tissue distribution of antileukoprotease and lysozyme in humans. J. Histochem. Cytochem. 37:493-498.
10. Kramps, J. A., C. Franken, and J. H. Dijkman. 1984. ELISA for quantitative measurement of low-molecular-weight bronchial protease inhibitor in sputum. Am. Rev. Respir. Dis. 129:959-963.
11. Kramps, J. A., C. Franken, and J. H. Dijkman. 1988. Quantity of anti-leucoprotcase relative to α1-proteinase inhibitor in peripheral airspaces of the human lung. Clin. Sci. 75:351-353.
12. Kramps, J. A., C. Franken, C. J. L. M. Meijer, and J. H. Dijkman. 1981. Localization of low molecular weight protease inhibitor in serous secretory cells of the respiratory tract. J. Histochem. Cytochem. 29:712-719.
13. Kramps, J. A., and E. C. Klasen. 1985. Characterization of a low molecular weight anti-elastase isolated from bronchial secretion. Exp. Lung Res. 9:151-165.
14. Kramps, J. A., A. Rudolphus, J. Stolk, L. N. A. Willems, and J. H. Dijkman. 1991. Role of antileukoprotease in the human lung, Ann. N. Y. Acad. Sci. 624:97-108.
15. Kramps, J. A., P. van der Valk, M. M. van der Sandt, J. Lindeman, and C. J. L. M. Meijer. 1984. Elastase as a marker for neutrophilic myeloid cells. J. Histochem. Cytochem. 32:389-394.
16. Kramps, J. A., Ch. Van Twisk, H. Appelhans, B. Meckelein, T. Nikiforov, and J. H. Dijkman. 1990. Proteinase inhibitory activities of antileukoprotease are represented by its second COOH-terminal domain. Biochim. Biophys. Acta 1038:178-185.
17. Kramps, J. A., L. N. A. Willems, R. De Water, C. Franken, and J. H. Dijkman. 1991. Bronchial secreting cells and antileukoprotease, p. 235-245. In A. Junod, D. Olivieri. and E. Pozzi (ed.), Endothelial and mucus secreting cells. Masson, Milan.
18. Lehrer, R. L. A. Barton, and T. Ganz. 1988. Concurrent assessment of inner and outer membrane permeabilization and bacteriolysis in E. coli by multiple-wavelength spectrophotometry. J. Immunol. Methods 108:153-158.
19. Lehrer, R. I., and T. Ganz. 1990. Antimicrobial polypeptidcs of human neutrophils. Blood 76:2169-2181.
20. Lehrer, R. I., M. Rosenman, S. S. L. Harwig, R. Jackson, and P. Eisenhauer. 1991. Ultrasensitive assays for endogenous antimicrobial polypeptides. J. Immunol. Methods 137:167-173.
21. Leijh, P. C. J., R. Van Furth, and T. L. Van Zwet. 1986. In vitro determination of phagocytosis and intracellular killing by polymorphonuclear and mononuclcar phagocytes, p. 46.1-46.21. In D. M. Weir (ed.), Handbook of experimental immunology, vol. 2. Cellular immunology. Blackwell Scientific Publications, Oxford.
22. Martin, E., T. Ganz, and R. I. Lehrer. 1995. Defensins and other endogenous peptide antibiotics of vertebrates. J. Leukocyte Biol. 58:128-136.
23. McElvaney, N. G., R. C. Hubbard, P. Birrer, M. S. Chernick, D. B. Caplan, M. M. Frank, and R. G. Crystal. 1991. Aerosol alpha 1-antitrypsin treatment for cystic fibrosis. Lancet 337:392-394.
24. McElvaney, N. G., H. Nakamura, P. Birrer, C. A. Hebert, W. L. Wong, M. Alphonso, J. B. Baker, M. A. Catalano, and R. G. Crystal. 1992. Modulation of airway inflammation in cystic fibrosis. In vivo suppression of interleukin-8 levels on the respiratory epithelial surface by aerolization of recombinant secretory leukoprotease inhibitor. J. Clin. Invest. 90:1296-1301.
25. McNeely, T. B., M. Dealy, D. J. Dripps, J. M. Orenstein, S. P. Eisenberg, and S. M. Wahl. 1995. Secretory leukocyte protease inhibitor: a human saliva protein exhibiting anti-human immunodeficiency virus 1 activity in vitro. J. Clin. Invest. 96:456-464.
26. Meckelein, B., T. Nikiforov, A. Clemen, and H. Appelhans. 1990. The location of inhibitory specificities in human mucus proteinase inhibitor (MPI): separate expression of the COOH-terminal domain yields an active inhibitor of three different proteinases. Protein Eng. 3:215-220.
27. Miller, K. W., R. J. Evans, S. P. Eisenberg, and R. C. Thompson. 1989. Secretory leukocyte protease inhibitor binding to mRNA and DNA as a possible cause of toxicity to Escherichia coli. J. Bacteriol. 171:2166-2172.
28. Pellegrini, A., U. Thomas, R. von Fellenberg, and P. Wild. 1992. Bactericidal activities of lysozyme and aprotinin against gram-negative and gram-positive bacteria related to their basic character. J. Appl. Bacteriol. 72:180-187.
29. Rudolphus, A., R. Heinzel-Wieland, V. A. M. M. Vincent, D. Saunders, G. J. Steffens, and J. A. Kramps. 1991. Oxidation-resistant variants of recombinant antileucoprotease are better inhibitors of human-neutrophil-elastase-induced emphysema in hamsters than natural recombinant antileucoprotease. Clin. Sci. 81:777-784.
30. Schägger, H., and G. Von Jagow. 1987. Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1-100 kDa. Anal. Biochem. 166:368-379.
31. Schalkwijk, J., C. De Roo, and G. J. De Jongh. 1991. Skin-derived antileukoproteinase (SKALP), an elastase inhibitor from human keratinocytes. Purification and biochemical properties. Biochim. Biophys. Acta 1096:148-154.
32. Schill, W. B., and G. F. B. Schumaker. 1972. Radial diffusion in gel for micro determination of enzymes. I. Muraminidase, alpha amylase, DNAse I, RNAse I, acid phosphatase and alkaline phosphatase. Anal. Biochem. 46:502-533.
33. Seemuller, U., M. Arnhold, H. Fritz, K. Wiedenmann, W. Machleidt, R. Heinzel, H. Appelhans, H. G. Gassen, and F. Lottspeich. 1986. The acid-stable proteinase inhibitor of human mucous secretions (HUSI-I, antileukoprotease). Complete amino acid sequence as revealed by protein and cDNA sequencing and structural homology to whey proteins and Red Sea turtle proteinase inhibitor. FEBS Lett. 199:43-48.
34. Stockley, R. A. 1984. Measurement of soluble proteins in lung secretions. Thorax 39:241-247.
35. Stockley, R. A. 1987. α1-Antitrypsin and the pathogenesis of emphysema. Lung 165:61-77.
36. Tosi, M. F., H. Zakem, and M. Berger. 1990. Neutrophil elastase cleaves C3bi on opsonized Pseudomonas as well as CR1 on neutrophils to create a functionally important opsonin receptor mismatch. J. Clin. Invest. 86:300-308.
37. Van-Seuningen, I., and M. Davril. 1991. Separation of the two domains of human mucus proteinase inhibitor: inhibitory activity is only located in the carboxy-terminal domain. Biochem. Biophys. Res. Commun. 179:1587-1592.
38. Wiedow, O., J.-M. Schröder, H. Gregory, J. A. Young, and E. Christophers. 1990. Elafin: an elastasc-specific inhibitor of human skin. Purification, characterization, and complete amino acid sequence. J. Biol. Chem. 265:14791-14795.
39. Ying, Q.-L., M. Kemme, and S. R. Simon. 1994. Functions of the N-terminal domain of secretory leukoprotease inhibitor. Biochemistry 33:5445-5450.