Arginase: A key enzyme in the pathophysiology of allergic asthma opening novel therapeutic perspectives

British Journal of Pharmacology

Volumn 158, Issue 3, 2009, Pages 652-664

  Maarsingh, Harm ^a   Zaagsma, Johan ^a   Meurs, Herman ^a  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

Author keywords

Airway hyperresponsiveness; Airway remodelling; Allergy; Arginase inhibitors; Arginine; Collagen; Inflammation; Nitric oxide; Peroxynitrite; Polyamines

Indexed keywords

2 AMINO 6 BORONOHEXANOIC ACID; ARGINASE; ARGININE; COLLAGEN; CYTOKINE; ENZYME INHIBITOR; INDUCIBLE NITRIC OXIDE SYNTHASE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; ORNITHINE; PEROXYNITRITE; UNCLASSIFIED DRUG;

ALLERGIC ASTHMA; AMINO ACID SYNTHESIS; BIOAVAILABILITY; CELL PROLIFERATION; DRUG EFFICACY; DRUG TARGETING; ENZYME ACTIVITY; ENZYME INHIBITION; EX VIVO STUDY; GENE EXPRESSION; HUMAN; IMMUNOREACTIVITY; IN VIVO STUDY; LUNG LAVAGE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN FUNCTION; REGULATORY MECHANISM; REVIEW;

AIRWAY REMODELING; ANIMALS; ANTI-ALLERGIC AGENTS; ANTI-INFLAMMATORY AGENTS; ARGINASE; ASTHMA; BRONCHIAL HYPERREACTIVITY; HUMANS; INFLAMMATION; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; RESPIRATORY PHYSIOLOGICAL PHENOMENA;

EID: 70350051180     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2009.00374.x     Document Type: Review

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