메뉴 건너뛰기




Volumn 142, Issue 8, 2004, Pages 1293-1299

Heparin normalizes allergen-induced nitric oxide deficiency and airway hyperresponsiveness

Author keywords

Airway hyperresponsiveness; Allergic asthma; Cationic amino acid transporter; Early asthmatic reaction; Eosinophils; Guinea pig; Heparin; L Arginine; Nitric oxide synthase; Polycations

Indexed keywords

ALLERGEN; HEPARIN; METHACHOLINE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR; OVALBUMIN; POLYCATION;

EID: 4444318121     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0705848     Document Type: Article
Times cited : (19)

References (41)
  • 1
    • 0027415859 scopus 로고
    • Allergen-induced recruitment of inflammatory cells in lavage 3 and 24 h after challenge in allergic asthmatic lungs
    • AALBERS, R., KAUFFMAN, H.F., VRUGT, B., KOETER, G.H. & DE MONCHY, J.G. (1993). Allergen-induced recruitment of inflammatory cells in lavage 3 and 24 h after challenge in allergic asthmatic lungs. Chest, 103, 1178-1184.
    • (1993) Chest , vol.103 , pp. 1178-1184
    • Aalbers, R.1    Kauffman, H.F.2    Vrugt, B.3    Koeter, G.H.4    De Monchy, J.G.5
  • 2
    • 0030968807 scopus 로고    scopus 로고
    • Inhibition of antigen-induced acute bronchoconstriction, airway hyperresponsiveness, and mast cell degranulation by a nonanticoagulant heparin: Comparison with a low molecular weight heparin
    • AHMED, T., CAMPO, C., ABRAHAM, M.K., MOLINARI, J.F., ABRAHAM, W.M., ASHKIN, D., SYRISTE, T., ANDERSSON, L.O. & SVAHN, C.M. (1997). Inhibition of antigen-induced acute bronchoconstriction, airway hyperresponsiveness, and mast cell degranulation by a nonanticoagulant heparin: comparison with a low molecular weight heparin. Am. J. Respir. Crit. Care Med., 155, 1848-1855.
    • (1997) Am. J. Respir. Crit. Care Med. , vol.155 , pp. 1848-1855
    • Ahmed, T.1    Campo, C.2    Abraham, M.K.3    Molinari, J.F.4    Abraham, W.M.5    Ashkin, D.6    Syriste, T.7    Andersson, L.O.8    Svahn, C.M.9
  • 3
    • 0027159470 scopus 로고
    • Preventing bronchoconstriction in exercise-induced asthma with inhaled heparin
    • AHMED, T., GARRIGO, J. & DANTA, I. (1993). Preventing bronchoconstriction in exercise-induced asthma with inhaled heparin. N. Engl. J. Med., 329, 90-95.
    • (1993) N. Engl. J. Med. , vol.329 , pp. 90-95
    • Ahmed, T.1    Garrigo, J.2    Danta, I.3
  • 5
    • 0034087906 scopus 로고    scopus 로고
    • Inhibition of allergic late airway responses by inhaled heparin-derived oligosaccharides
    • AHMED, T., UNGO, J., ZHOU, M. & CAMPO, C. (2000). Inhibition of allergic late airway responses by inhaled heparin-derived oligosaccharides. J. Appl. Physiol., 88, 1721-1729.
    • (2000) J. Appl. Physiol. , vol.88 , pp. 1721-1729
    • Ahmed, T.1    Ungo, J.2    Zhou, M.3    Campo, C.4
  • 6
    • 0027434514 scopus 로고
    • Heparin inhibits the immediate response to antigen in the skin and lungs of allergic subjects
    • BOWLER, S.D., SMITH, S.M. & LAVERCOMBE, P.S. (1993). Heparin inhibits the immediate response to antigen in the skin and lungs of allergic subjects. Am. Rev. Respir. Dis., 147, 160-163.
    • (1993) Am. Rev. Respir. Dis. , vol.147 , pp. 160-163
    • Bowler, S.D.1    Smith, S.M.2    Lavercombe, P.S.3
  • 7
    • 0028911135 scopus 로고
    • Effect of inhaled heparin on methacholine-induced bronchial hyperreactivity
    • CEYHAN, B. & CELIKEL, T. (1995). Effect of inhaled heparin on methacholine-induced bronchial hyperreactivity. Chest, 107, 1009-1012.
    • (1995) Chest , vol.107 , pp. 1009-1012
    • Ceyhan, B.1    Celikel, T.2
  • 8
    • 0033811380 scopus 로고    scopus 로고
    • Effect of inhaled low molecular weight heparin on methacholine-induced bronchoconstriction
    • CEYHAN, B.B. & CELIKEL, T. (2000). Effect of inhaled low molecular weight heparin on methacholine-induced bronchoconstriction. Int. J. Clin. Pharmacol. Ther., 38, 446-451.
    • (2000) Int. J. Clin. Pharmacol. Ther. , vol.38 , pp. 446-451
    • Ceyhan, B.B.1    Celikel, T.2
  • 9
  • 10
    • 0029794514 scopus 로고    scopus 로고
    • CATs, a family of three distinct mammalian cationic amino acid transporters
    • CLOSS, E.I. (1996). CATs, a family of three distinct mammalian cationic amino acid transporters. Amino Acids, 11, 193-208.
    • (1996) Amino Acids , vol.11 , pp. 193-208
    • Closs, E.I.1
  • 11
    • 0027476449 scopus 로고
    • Cationic proteins induce airway hyperresponsiveness dependent on charge interactions
    • COYLE, A.J., ACKERMAN, S.J. & IRVIN, C.G. (1993). Cationic proteins induce airway hyperresponsiveness dependent on charge interactions. Am. Rev. Respir. Dis., 147, 896-900.
    • (1993) Am. Rev. Respir. Dis. , vol.147 , pp. 896-900
    • Coyle, A.J.1    Ackerman, S.J.2    Irvin, C.G.3
  • 12
    • 0032755339 scopus 로고    scopus 로고
    • Role of L-arginine in the deficiency of nitric oxide and airway hyperreactivity after the allergen-induced early asthmatic reaction in guinea-pigs
    • DE BOER, J., DUYVENDAK, M., SCHUURMAN, F.E., POUW, F.M., ZAAGSMA, J. & MEURS, H. (1999). Role of L-arginine in the deficiency of nitric oxide and airway hyperreactivity after the allergen-induced early asthmatic reaction in guinea-pigs. Br. J. Pharmacol., 128, 1114-1120.
    • (1999) Br. J. Pharmacol. , vol.128 , pp. 1114-1120
    • De Boer, J.1    Duyvendak, M.2    Schuurman, F.E.3    Pouw, F.M.4    Zaagsma, J.5    Meurs, H.6
  • 13
    • 0029949609 scopus 로고    scopus 로고
    • Deficiency of nitric oxide in allergen-induced airway hyperreactivity to contractile agonists after the early asthmatic reaction: An ex vivo study
    • DE BOER, J., MEURS, H., COERS, W., KOOPAL, M., BOTTONE, A.E., VISSER, A.C., TIMENS, W. & ZAAGSMA, J. (1996). Deficiency of nitric oxide in allergen-induced airway hyperreactivity to contractile agonists after the early asthmatic reaction: an ex vivo study. Br. J. Pharmacol., 119, 1109-1116.
    • (1996) Br. J. Pharmacol. , vol.119 , pp. 1109-1116
    • De Boer, J.1    Meurs, H.2    Coers, W.3    Koopal, M.4    Bottone, A.E.5    Visser, A.C.6    Timens, W.7    Zaagsma, J.8
  • 14
    • 0029934168 scopus 로고    scopus 로고
    • Effect of inhaled heparin on allergen-induced early and late asthmatic responses in patients with atopic asthma
    • DIAMANT, Z., TIMMERS, M.C., VAN, D.V., PAGE, C.P., VAN DER MEER, F.J. & STERK, P.J. (1996). Effect of inhaled heparin on allergen-induced early and late asthmatic responses in patients with atopic asthma. Am. J. Respir. Crit. Care Med., 153, 1790-1795.
    • (1996) Am. J. Respir. Crit. Care Med. , vol.153 , pp. 1790-1795
    • Diamant, Z.1    Timmers, M.C.2    Van, D.V.3    Page, C.P.4    Van Der Meer, F.J.5    Sterk, P.J.6
  • 15
    • 0027008588 scopus 로고
    • Function of pulmonary M2 muscarinic receptors in antigen-challenged guinea pigs is restored by heparin and poly-L-glutamate
    • FRYER, A.D. & JACOBY, D.B. (1992). Function of pulmonary M2 muscarinic receptors in antigen-challenged guinea pigs is restored by heparin and poly-L-glutamate. J. Clin. Invest., 90, 2292-2298.
    • (1992) J. Clin. Invest. , vol.90 , pp. 2292-2298
    • Fryer, A.D.1    Jacoby, D.B.2
  • 16
    • 0031787012 scopus 로고    scopus 로고
    • Muscarinic receptors and control of airway smooth muscle
    • FRYER, A.D. & JACOBY, D.B. (1998). Muscarinic receptors and control of airway smooth muscle. Am. J. Respir. Crit. Care Med., 158, S154-S160.
    • (1998) Am. J. Respir. Crit. Care Med. , vol.158
    • Fryer, A.D.1    Jacoby, D.B.2
  • 17
    • 0029925092 scopus 로고    scopus 로고
    • Time course of the protective effect of inhaled heparin on exercise-induced asthma
    • GARRIGO, J., DANTA, I. & AHMED, T. (1996). Time course of the protective effect of inhaled heparin on exercise-induced asthma. Am. J. Respir. Crit. Care Med., 153, 1702-1707.
    • (1996) Am. J. Respir. Crit. Care Med. , vol.153 , pp. 1702-1707
    • Garrigo, J.1    Danta, I.2    Ahmed, T.3
  • 18
    • 0023690141 scopus 로고
    • Competitive, reversible, and potent antagonism of inositol 1,4,5-trisphosphate-activated calcium release by heparin
    • GHOSH, T.K., EIS, P.S., MULLANEY, J.M., EBERT, C.L. & GILL, D.L. (1988). Competitive, reversible, and potent antagonism of inositol 1,4,5-trisphosphate-activated calcium release by heparin. J. Biol. Chem., 263, 11075-11079.
    • (1988) J. Biol. Chem. , vol.263 , pp. 11075-11079
    • Ghosh, T.K.1    Eis, P.S.2    Mullaney, J.M.3    Ebert, C.L.4    Gill, D.L.5
  • 20
    • 0031951948 scopus 로고    scopus 로고
    • Airway smooth muscle cell proliferation: Characterization of subpopulations by sensitivity to heparin inhibition
    • HALAYKO, A.J., RECTOR, E. & STEPHENS, N.L. (1998). Airway smooth muscle cell proliferation: characterization of subpopulations by sensitivity to heparin inhibition. Am. J. Physiol., 274, L17-L25.
    • (1998) Am. J. Physiol. , vol.274
    • Halayko, A.J.1    Rector, E.2    Stephens, N.L.3
  • 21
    • 0033172721 scopus 로고    scopus 로고
    • Cationic proteins inhibit L-arginine uptake in rat alveolar macrophages and tracheal epithelial cells. Implications for nitric oxide synthesis
    • HAMMERMANN, R., HIRSCHMANN, J., HEY, C., MOSSNER, J., FOLKERTS, G., NIJKAMP, F.P., WESSLER, I. & RACKE, K. (1999). Cationic proteins inhibit L-arginine uptake in rat alveolar macrophages and tracheal epithelial cells. Implications for nitric oxide synthesis. Am. J. Respir. Cell Mol. Biol., 21, 155-162.
    • (1999) Am. J. Respir. Cell Mol. Biol. , vol.21 , pp. 155-162
    • Hammermann, R.1    Hirschmann, J.2    Hey, C.3    Mossner, J.4    Folkerts, G.5    Nijkamp, F.P.6    Wessler, I.7    Racke, K.8
  • 22
    • 0023031865 scopus 로고
    • A multinuclear NMR study of the interactions of cations with proteoglycans, heparin, and ficoll
    • LERNER, L. & TORCHIA, D.A. (1986). A multinuclear NMR study of the interactions of cations with proteoglycans, heparin, and ficoll. J. Biol. Chem., 261, 12706-12714.
    • (1986) J. Biol. Chem. , vol.261 , pp. 12706-12714
    • Lerner, L.1    Torchia, D.A.2
  • 24
    • 0033845785 scopus 로고    scopus 로고
    • Modulation of cholinergic airway reactivity and nitric oxide production by endogenous arginase activity
    • MEURS, H., HAMER, M.A., PETHE, S., VADON-LE GOFF, S., BOUCHER, J.L. & ZAAGSMA, J. (2000). Modulation of cholinergic airway reactivity and nitric oxide production by endogenous arginase activity. Br. J. Pharmacol., 130, 1793-1798.
    • (2000) Br. J. Pharmacol. , vol.130 , pp. 1793-1798
    • Meurs, H.1    Hamer, M.A.2    Pethe, S.3    Vadon-Le Goff, S.4    Boucher, J.L.5    Zaagsma, J.6
  • 25
    • 0041878667 scopus 로고    scopus 로고
    • Arginase and asthma: Novel insights into nitric oxide homeostasis and airway hyperresponsiveness
    • MEURS, H., MAARSINGH, H. & ZAAGSMA, J. (2003). Arginase and asthma: novel insights into nitric oxide homeostasis and airway hyperresponsiveness. Trends Pharmacol. Sci., 24, 450-455.
    • (2003) Trends Pharmacol. Sci. , vol.24 , pp. 450-455
    • Meurs, H.1    Maarsingh, H.2    Zaagsma, J.3
  • 26
    • 0036016110 scopus 로고    scopus 로고
    • Increased arginase activity underlies allergen-induced deficiency of cNOS-derived nitric oxide and airway hyperresponsiveness
    • MEURS, H., MCKAY, S., MAARSINGH, H., HAMER, M.A., MACIC, L., MOLENDIJK, N. & ZAAGSMA, J. (2002). Increased arginase activity underlies allergen-induced deficiency of cNOS-derived nitric oxide and airway hyperresponsiveness. Br. J. Pharmacol., 136, 391-398.
    • (2002) Br. J. Pharmacol. , vol.136 , pp. 391-398
    • Meurs, H.1    Mckay, S.2    Maarsingh, H.3    Hamer, M.A.4    Macic, L.5    Molendijk, N.6    Zaagsma, J.7
  • 27
    • 0033055177 scopus 로고    scopus 로고
    • Deficiency of nitric oxide in polycation-induced airway hyperreactivity
    • MEURS, H., SCHUURMAN, F.E., DUYVENDAK, M. & ZAAGSMA, J. (1999). Deficiency of nitric oxide in polycation-induced airway hyperreactivity. Br. J. Pharmacol., 126, 559-562.
    • (1999) Br. J. Pharmacol. , vol.126 , pp. 559-562
    • Meurs, H.1    Schuurman, F.E.2    Duyvendak, M.3    Zaagsma, J.4
  • 28
    • 0031922544 scopus 로고    scopus 로고
    • Inhibition of antigen-induced airway hyperresponsiveness by ultralow molecular-weight heparin
    • MOLINARI, J.F., CAMPO, C., SHAKIR, S. & AHMED, T. (1998). Inhibition of antigen-induced airway hyperresponsiveness by ultralow molecular-weight heparin. Am. J. Respir. Crit. Care Med., 157, 887-893.
    • (1998) Am. J. Respir. Crit. Care Med. , vol.157 , pp. 887-893
    • Molinari, J.F.1    Campo, C.2    Shakir, S.3    Ahmed, T.4
  • 29
    • 0024500320 scopus 로고
    • Toxicity of eosinophil cationic proteins for guinea-pig tracheal epithelium in vitro
    • MOTOJIMA, S., FRIGAS, E., LOEGERING, D.A. & GLEICH, G.J. (1989). Toxicity of eosinophil cationic proteins for guinea-pig tracheal epithelium in vitro. Am. Rev. Respir. Dis., 139, 801-805.
    • (1989) Am. Rev. Respir. Dis. , vol.139 , pp. 801-805
    • Motojima, S.1    Frigas, E.2    Loegering, D.A.3    Gleich, G.J.4
  • 31
    • 0028110191 scopus 로고
    • The importance of eosinophil activation for the development of allergen-induced bronchial hyperreactivity in conscious, unrestrained guinea-pigs
    • SANTING, R.E., HOEKSTRA, Y., PASMAN, Y., ZAAGSMA, J. & MEURS, H. (1994a). The importance of eosinophil activation for the development of allergen-induced bronchial hyperreactivity in conscious, unrestrained guinea-pigs. Clin. Exp. Allergy, 24, 1157-1163.
    • (1994) Clin. Exp. Allergy , vol.24 , pp. 1157-1163
    • Santing, R.E.1    Hoekstra, Y.2    Pasman, Y.3    Zaagsma, J.4    Meurs, H.5
  • 33
    • 0028291977 scopus 로고
    • Relationships among allergen-induced early and late phase airway obstructions, bronchial hyperreactivity, and inflammation in conscious, unrestrained guinea pigs
    • SANTING, R.E., OLYMULDER, C.G., ZAAGSMA, J. & MEURS, H. (1994b). Relationships among allergen-induced early and late phase airway obstructions, bronchial hyperreactivity, and inflammation in conscious, unrestrained guinea pigs. J. Allergy Clin. Immunol., 93, 1021-1030.
    • (1994) J. Allergy Clin. Immunol. , vol.93 , pp. 1021-1030
    • Santing, R.E.1    Olymulder, C.G.2    Zaagsma, J.3    Meurs, H.4
  • 34
    • 0032134205 scopus 로고    scopus 로고
    • L-arginine uptake and metabolism by lung macrophages and neutrophils following intratracheal instillation of silica in vivo
    • SCHAPIRA, R.M., WIESSNER, J.H., MORRISEY, J.F., ALMAGRO, U.A. & NELIN, L.D. (1998). L-arginine uptake and metabolism by lung macrophages and neutrophils following intratracheal instillation of silica in vivo. Am. J. Respir. Cell Mol. Biol., 19, 308-315.
    • (1998) Am. J. Respir. Cell Mol. Biol. , vol.19 , pp. 308-315
    • Schapira, R.M.1    Wiessner, J.H.2    Morrisey, J.F.3    Almagro, U.A.4    Nelin, L.D.5
  • 35
    • 0034967578 scopus 로고    scopus 로고
    • Heparin inhibits allergen-induced eosinophil infiltration into guinea-pig lung via a mechanism unrelated to its anticoagulant activity
    • SEEDS, E.A. & PAGE, C.P. (2001). Heparin inhibits allergen-induced eosinophil infiltration into guinea-pig lung via a mechanism unrelated to its anticoagulant activity. Pulmon. Pharmacol. Ther., 14, 111-119.
    • (2001) Pulmon. Pharmacol. Ther. , vol.14 , pp. 111-119
    • Seeds, E.A.1    Page, C.P.2
  • 37
    • 0027509685 scopus 로고
    • The effect of human eosinophil granule major basic protein on airway responsiveness in the rat in vivo. A comparison with polycations
    • UCHIDA, D.A., ACKERMAN, S.J., COYLE, A.J., LARSEN, G.L., WELLER, P.F., FREED, J. & IRVIN, C.G. (1993). The effect of human eosinophil granule major basic protein on airway responsiveness in the rat in vivo. A comparison with polycations. Am. Rev. Respir. Dis., 147, 982-988.
    • (1993) Am. Rev. Respir. Dis. , vol.147 , pp. 982-988
    • Uchida, D.A.1    Ackerman, S.J.2    Coyle, A.J.3    Larsen, G.L.4    Weller, P.F.5    Freed, J.6    Irvin, C.G.7
  • 38
    • 0024528029 scopus 로고
    • Analysis of the beta-adrenoceptor mediated inhibition of IgG1 and IgE dependent guinea-pig anaphylactic tracheal smooth muscle contraction
    • VAN AMSTERDAM, R.G., BROUWER, F. & ZAAGSMA, J. (1989). Analysis of the beta-adrenoceptor mediated inhibition of IgG1 and IgE dependent guinea-pig anaphylactic tracheal smooth muscle contraction. Agents Actions, 26, 48-51.
    • (1989) Agents Actions , vol.26 , pp. 48-51
    • Van Amsterdam, R.G.1    Brouwer, F.2    Zaagsma, J.3
  • 39
    • 0023831561 scopus 로고
    • Eosinophils and mast cells in bronchoalveolar lavage in subjects with mild asthma
    • WARDLAW, A.J., DUNNETTE, S., GLEICH, G.J., COLLINS, J.C. & KAY, A. (1988). Eosinophils and mast cells in bronchoalveolar lavage in subjects with mild asthma. Am. Rev. Respir. Dis., 137, 62-69.
    • (1988) Am. Rev. Respir. Dis. , vol.137 , pp. 62-69
    • Wardlaw, A.J.1    Dunnette, S.2    Gleich, G.J.3    Collins, J.C.4    Kay, A.5
  • 40
    • 0026000283 scopus 로고
    • A kinetic assay for eosinophil peroxidase activity in eosinophils and eosinophil conditioned media
    • WHITE, S.R., KULP, G.V.P., SPAETHE, S.M., VAN ALSTYNE, E. & LEFF, A.R. (1991). A kinetic assay for eosinophil peroxidase activity in eosinophils and eosinophil conditioned media. J. Immunol. Methods, 44, 257-263.
    • (1991) J. Immunol. Methods , vol.44 , pp. 257-263
    • White, S.R.1    Kulp, G.V.P.2    Spaethe, S.M.3    Van Alstyne, E.4    Leff, A.R.5
  • 41
    • 0037005735 scopus 로고    scopus 로고
    • Modulation of airway responsiveness by anionic and cationic polyelectrolyte substances
    • YAHATA, T., NISHIMURA, Y., MAEDA, H. & YOKOYAMA, M. (2002). Modulation of airway responsiveness by anionic and cationic polyelectrolyte substances. Eur. J. Pharmacol., 434, 71-79.
    • (2002) Eur. J. Pharmacol. , vol.434 , pp. 71-79
    • Yahata, T.1    Nishimura, Y.2    Maeda, H.3    Yokoyama, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.