Deficiency of nitric oxide in polycation-induced airway hyperreactivity

British Journal of Pharmacology

Volumn 126, Issue 3, 1999, Pages 559-562

  Meurs, Herman ^a   Schuurman, Fineke E ^a   Duyvendak, Michiel ^a   Zaagsma, Johan ^a  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

Author keywords

Airway hyperreactivity; Guinea pig; Heparin; Methacholine; N( ) nitro L arginine methyl ester; Nitric oxide; Poly L arginine; Tracheal perfusion

Indexed keywords

ARGININE METHYL ESTER; HEPARIN; METHACHOLINE; NITRIC OXIDE; POLYARGININE;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GUINEA PIG; NONHUMAN; PRIORITY JOURNAL; TRACHEA;

ANIMALS; BRONCHIAL HYPERREACTIVITY; BRONCHOCONSTRICTION; BRONCHOCONSTRICTOR AGENTS; ENZYME INHIBITORS; GUINEA PIGS; HEPARIN; METHACHOLINE CHLORIDE; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; PEPTIDES; POLYAMINES; POLYMERS; SPECIFIC PATHOGEN-FREE ORGANISMS; TRACHEA;

EID: 0033055177     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0702372     Document Type: Article

References (18)

1. COYLE, A.J., ACKERMAN, S.J. & IRVIN, C.G. (1993a). Cationic proteins induce airway hyperresponsiveness dependent on charge interactions. Am. Rev. Respir. Dis., 147, 896-900.
2. COYLE, A.J., MITZNER, W. & IRVIN, C.G. (1993b). Cationic proteins alter smooth muscle function by an epithelium-dependent mechanism. J. Appl. Physiol., 74, 1761-1768.
3. DE BOER, J., MEURS, H., COERS, W., KOOPAL, M., BOTTONE, A.E., VISSER, A.C., TIMENS, W. & ZAAGSMA, J. (1996). Deficiency of nitric oxide in allergen-induced airway hyperreactivity to contractile agonists after the early asthmatic reaction. An ex vivo study. Br. J. Pharmacol., 116, 1109-1116.
4. FLAVAHAN, N.A., SLIFMAN, N.R., GLEICH, G.J. & VANHOUTTE, P.M. (1988). Human eosinophil major basic protein causes hyperreactivity of respiratory smooth muscle. Am. Rev. Respir. Dis., 138, 685-688.
5. GLEICH, G.J., ADOLPHSON, C.R. & LEIFERMAN, K.M. (1993). The biology of the eosinophilic leukocyte. Annu. Rev. Med., 44, 85-101.
6. HIRSCHMANN, J., HEY, C., HAMMERMANN, J.G., FOLKERTS, J.G., NIJKAMP, F.P., GLEICH, G.J., WESSLER, I. & RACKÉ, K. (1998). Inhibition of L-arginine transport in rat and guinea pig alveolar macrophages (AMφ) by poly-cationic peptides. Br. J. Pharmacol., 123, 177P.
7. HULSMANN, A.R., RAATGREEP, H.R., DEN HOLLANDER, J.C., BAKKER, W.H., SAXENA, P.R. & DE JONGSTE, J.C. (1996). Permeability of human isolated airways increases after hydrogen peroxide and poly-L-arginine. Am. J. Respir. Crit. Care Med., 153, 841-846.
8. KOBZIK, L., BREDT, D.S., LOWENSTEIN, C.J., DRAZEN, J., GASTON, B., SUGARBAKER, D. & STAMLER, J.S. (1993). Nitric oxide synthase in human and rat lung: immunocytochemical and histochemical localization. Am. J. Respir. Cell. Mol. Biol., 9, 371-377.
9. MEURS, H., DE BOER, J., DUYVENDAK, M., SCHUURMAN, F.E. & ZAAGSMA, J. (1999). Role for L-arginine, but not for superoxide anions, in the deficiency of nitric oxide after the allergen-induced early asthmatic reaction in guinea pigs (abstract). Clin. Exp. Allerg, (in press).
10. MOTOJIMA, S., FRIGAS, E., LOWGERING, D.A. & GLEICH, G.J. (1989). Toxicity of eosinophil cationic proteins for guinea pig tracheal epithelium in vitro. Am. Rev. Respir. Dis., 139, 801-805.
11. MUNAKATA, M., HUANG, I., MITZNER, W. & MENKES, H. (1989). Protective role of epithelium in the guinea pig airway. J. Appl. Physiol., 66, 1547-1552.
12. NIJKAMP, F.P., VAN DER LINDE, H.J. & FOLKERTS, G. (1993). Nitric oxide synthesis inhibitors induce airway hyperresponsiveness in the guinea pig in vivo and in vitro. Am. Rev. Respir. Dis., 148, 727-734.
13. OMARI, T., SPARROW, M.P., CHURCH, M.K., HOLGATE, S.T. & ROBINSON, C. (1993). A comparison of the effects of polyarginine and stimulated eosinophils on the responsiveness of the bovine isovolumic bronchial segment preparation. Br. J. Pharmacol., 109, 553-561.
14. RICCIARDOLO, F.L.M., DI MARIA, G.U., MISTRETTA, A., SAPIENZA, M.A. & GEPETTI, P. (1997). Impairment of bronchoprotection by nitric oxide in severe asthma. Lancet, 350, 1297-1298.
15. SANTING, R.E., OLYMULDER, C.G., ZAAGSMA, J. & MEURS, H. (1994). Relationships among allergen-induced early and late phase airway obstructions, bronchial hyperreactivity, and inflammation in conscious, unrestrained guinea pigs. J. Allergy Clin. Immunol., 93, 1021-1030.
16. SCHUILING, M., ZUIDHOF, A.B., BONOUVRIE, A.A., VENEMA, N., ZAAGSMA, J. & MEURS, H. (1998). Role of nitric oxide in the development and partial reversal of allergen-induced airway hyperreactivity in conscious, unrestrained guinea-pigs. Br. J. Pharmacol., 123, 1450-1456.
17. UCHIDA, D.A., ACKERMAN, S.J., COYLE, A.J., LARSEN, G.L., WELLER, P.F., FREED, J. & IRVIN, C.G. (1993). The effect of human eosinophil granule major basic protein on airway responsiveness in the rat in vivo. A comparison with polycations. Am. Rev. Respir. Dis., 147, 982-988.
18. WARDLAW, A.J., DUNNETTE, S., GLEICH, G.J., COLLINS, J.V. & KAY, A.B. (1988). Eosinophils and mast cells in bronchoalveolar lavage in subjects with mild asthma. Am. Rev. Respir. Dis., 137, 62-69.