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Volumn 156, Issue 1, 2009, Pages 84-93

The vascular effects of different arginase inhibitors in rat i/ated aorta and mesenteric arteries

Author keywords

Aorta; Arginase; L arginine; Mesenteric arteries; Nitric oxide; Vasorelaxation

Indexed keywords

(2 BORONOETHYL)CYSTEINE; ACETYLCHOLINE; ARGINASE; ARGININE; CYSTEINE DERIVATIVE; EFLORNITHINE; N OMEGA HYDROXYNORARGININE; N(G) HYDROXYARGININE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NORVALINE; UNCLASSIFIED DRUG; VALINE; (2 BORONOETHYL) CYSTEINE; (2-BORONOETHYL)-CYSTEINE; BORONIC ACID DERIVATIVE; DRUG DERIVATIVE; N(OMEGA) HYDROXYARGININE; N(OMEGA) HYDROXYNORARGININE; N(OMEGA)-HYDROXYARGININE; N(OMEGA)-HYDROXYNORARGININE; VASODILATOR AGENT;

EID: 65549138846     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2008.00036.x     Document Type: Article
Times cited : (36)

References (51)
  • 1
    • 0029948497 scopus 로고    scopus 로고
    • Mechanisms mediating the vasodilatory effects of N-hydroxy-arginine in coronary arteries
    • Abdul-Hussain MN, Jia YL, Hussain SNA (1996). Mechanisms mediating the vasodilatory effects of N-hydroxy-arginine in coronary arteries. Eur J Pharmacol 305 : 155 161.
    • (1996) Eur J Pharmacol , vol.305 , pp. 155-161
    • Abdul-Hussain, M.N.1    Jia, Y.L.2    Hussain, S.N.A.3
  • 2
    • 40949095655 scopus 로고    scopus 로고
    • Guide to Receptors and Channels (GRAC), 3rd edition (2008 revision)
    • Suppl.
    • Alexander SPH, Mathie A, Peters JA (2008). Guide to Receptors and Channels (GRAC), 3rd edition (2008 revision). Br J Pharmacol 153 (Suppl. 2 S1 S209.
    • (2008) Br J Pharmacol , vol.153 , Issue.2
    • Alexander, S.P.H.1    Mathie, A.2    Peters, J.A.3
  • 4
    • 43449084960 scopus 로고    scopus 로고
    • Treatment with the arginase inhibitor N(omega)-hydroxy-nor-L-arginine improves vascular function and lowers blood pressure in adult spontaneously hypertensive rat
    • Bagnost T, Berthelot A, Bouhaddi M, Laurant P, Andre C, Guillaume Y et al. (2008). Treatment with the arginase inhibitor N(omega)-hydroxy-nor-L- arginine improves vascular function and lowers blood pressure in adult spontaneously hypertensive rat. J Hypertens 26 : 1110 1118.
    • (2008) J Hypertens , vol.26 , pp. 1110-1118
    • Bagnost, T.1    Berthelot, A.2    Bouhaddi, M.3    Laurant, P.4    Andre, C.5    Guillaume, Y.6
  • 5
    • 0142023863 scopus 로고    scopus 로고
    • Arginase reciprocally regulates nitric oxide synthase activity and contributes to endothelial dysfunction in aging blood vessels
    • Berkowitz DE, White R, Li D, Minhas KM, Cernetich A, Kim S et al. (2003). Arginase reciprocally regulates nitric oxide synthase activity and contributes to endothelial dysfunction in aging blood vessels. Circulation 108 : 2000 2006.
    • (2003) Circulation , vol.108 , pp. 2000-2006
    • Berkowitz, D.E.1    White, R.2    Li, D.3    Minhas, K.M.4    Cernetich, A.5    Kim, S.6
  • 6
    • 0028170690 scopus 로고
    • N[omega]-Hydroxy-L-Arginine, an intermediate in the L-arginine to Nitric Oxide pathway, is a strong inhibitor of liver and macrophage arginase
    • Boucher JL, Custot J, Vadon S, Delaforge M, Lepoivre M, Tenu JP et al. (1994). N[omega]-Hydroxy-L-Arginine, an intermediate in the L-arginine to Nitric Oxide pathway, is a strong inhibitor of liver and macrophage arginase. Biochem Biophys Res Commun 203 : 1614 1621.
    • (1994) Biochem Biophys Res Commun , vol.203 , pp. 1614-1621
    • Boucher, J.L.1    Custot, J.2    Vadon, S.3    Delaforge, M.4    Lepoivre, M.5    Tenu, J.P.6
  • 8
    • 0343551110 scopus 로고    scopus 로고
    • Arginase activity in endothelial cells: Inhibition by NG-hydroxy-L-arginine during high-output NO production
    • Buga GM, Singh R, Pervin S, Rogers NE, Schmitz DA, Jenkinson CP et al. (1996). Arginase activity in endothelial cells: inhibition by NG-hydroxy-L-arginine during high-output NO production. Am J Physiol 271 : H1988 98.
    • (1996) Am J Physiol , vol.271 , pp. 1988-98
    • Buga, G.M.1    Singh, R.2    Pervin, S.3    Rogers, N.E.4    Schmitz, D.A.5    Jenkinson, C.P.6
  • 9
    • 0038457032 scopus 로고    scopus 로고
    • Human arginase II: Crystal structure and physiological role in male and female sexual arousal
    • Cama E, Colleluori DM, Emig FA, Shin H, Kim SW, Kim NN et al. (2003a). Human arginase II: crystal structure and physiological role in male and female sexual arousal. Biochemistry 42 : 8445 8451.
    • (2003) Biochemistry , vol.42 , pp. 8445-8451
    • Cama, E.1    Colleluori, D.M.2    Emig, F.A.3    Shin, H.4    Kim, S.W.5    Kim, N.N.6
  • 10
    • 0038339405 scopus 로고    scopus 로고
    • Structural and functional importance of first-shell metal ligands in the binuclear manganese cluster of arginase i
    • Cama E, Emig FA, Ash DE, Christianson DW (2003b). Structural and functional importance of first-shell metal ligands in the binuclear manganese cluster of arginase I. Biochemistry 42 : 7748 7758.
    • (2003) Biochemistry , vol.42 , pp. 7748-7758
    • Cama, E.1    Emig, F.A.2    Ash, D.E.3    Christianson, D.W.4
  • 12
    • 0032919816 scopus 로고    scopus 로고
    • Acetylcholine-induced relaxation in blood vessels from endothelial nitric oxide synthase knockout mice
    • Chataigneau T, Feletou M, Huang PL, Fishman MC, Duhault J, Vanhoutte PM (1999). Acetylcholine-induced relaxation in blood vessels from endothelial nitric oxide synthase knockout mice. Br J Pharmacol 126 : 219 226.
    • (1999) Br J Pharmacol , vol.126 , pp. 219-226
    • Chataigneau, T.1    Feletou, M.2    Huang, P.L.3    Fishman, M.C.4    Duhault, J.5    Vanhoutte, P.M.6
  • 13
    • 0025099626 scopus 로고
    • Calcium dependency of the endothelium-dependent hyperpolarization in smooth muscle cells of the rabbit carotid artery
    • Chen GF, Suzuki H (1990). Calcium dependency of the endothelium-dependent hyperpolarization in smooth muscle cells of the rabbit carotid artery. J Physiol 421 : 521 534.
    • (1990) J Physiol , vol.421 , pp. 521-534
    • Chen, G.F.1    Suzuki, H.2
  • 14
    • 2942741190 scopus 로고    scopus 로고
    • Arginase inhibition increases nitric oxide production in bovine pulmonary arterial endothelial cells
    • Chicoine LG, Paffett ML, Young TL, Nelin LD (2004). Arginase inhibition increases nitric oxide production in bovine pulmonary arterial endothelial cells. Am J Physiol Lung Cell Mol Physiol 287 : L60 L68.
    • (2004) Am J Physiol Lung Cell Mol Physiol , vol.287
    • Chicoine, L.G.1    Paffett, M.L.2    Young, T.L.3    Nelin, L.D.4
  • 15
    • 0035822618 scopus 로고    scopus 로고
    • Classical and slow-binding inhibitors of human type II arginase
    • Colleluori DM, Ash DE (2001). Classical and slow-binding inhibitors of human type II arginase. Biochemistry 40 : 9356 9362.
    • (2001) Biochemistry , vol.40 , pp. 9356-9362
    • Colleluori, D.M.1    Ash, D.E.2
  • 16
    • 0035814932 scopus 로고    scopus 로고
    • Mechanistic and metabolic inferences from the binding of substrate analogues and products to arginase
    • Cox JD, Cama E, Colleluori DM, Pethe S, Boucher JL, Mansuy D et al. (2001). Mechanistic and metabolic inferences from the binding of substrate analogues and products to arginase. Biochemistry 40 : 2689 2701.
    • (2001) Biochemistry , vol.40 , pp. 2689-2701
    • Cox, J.D.1    Cama, E.2    Colleluori, D.M.3    Pethe, S.4    Boucher, J.L.5    Mansuy, D.6
  • 17
    • 0030990857 scopus 로고    scopus 로고
    • The new alpha-amino acid Nw- hydorxy-nor-L-arginine: A high -affinity inhibitor of arginase well adapted to bind to its manganese cluster
    • Custot J, Moali C, Brollo M, Boucher JL, Delaforge M, Mansuy D et al. (1997). The new alpha-amino acid Nw- hydorxy-nor-L-arginine: a high -affinity inhibitor of arginase well adapted to bind to its manganese cluster. J Am Chem Soc 119 : 4086 4087.
    • (1997) J Am Chem Soc , vol.119 , pp. 4086-4087
    • Custot, J.1    Moali, C.2    Brollo, M.3    Boucher, J.L.4    Delaforge, M.5    Mansuy, D.6
  • 18
    • 0028026967 scopus 로고
    • Inhibition of rat liver arginase by an intermediate in NO biosynthesis, NG-hydroxy-L-arginine: Implications for the regulation of nitric oxide biosynthesis by arginase
    • Daghigh F, Fukuto JM, Ash DE (1994). Inhibition of rat liver arginase by an intermediate in NO biosynthesis, NG-hydroxy-L-arginine: implications for the regulation of nitric oxide biosynthesis by arginase. Biochem Biophys Res Commun 202 : 174 180.
    • (1994) Biochem Biophys Res Commun , vol.202 , pp. 174-180
    • Daghigh, F.1    Fukuto, J.M.2    Ash, D.E.3
  • 19
    • 18344378606 scopus 로고    scopus 로고
    • Arginase inhibition reduces endothelial dysfunction and blood pressure rising in spontaneously hypertensive rats
    • Demougeot C, Prigent-Tessier A, Marie C, Berthelot A (2005). Arginase inhibition reduces endothelial dysfunction and blood pressure rising in spontaneously hypertensive rats. J Hypertens 23 : 971 978.
    • (2005) J Hypertens , vol.23 , pp. 971-978
    • Demougeot, C.1    Prigent-Tessier, A.2    Marie, C.3    Berthelot, A.4
  • 20
    • 0019195506 scopus 로고
    • The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine
    • Furchgott RF, Zawadzki JV (1980). The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature 288 : 373 376.
    • (1980) Nature , vol.288 , pp. 373-376
    • Furchgott, R.F.1    Zawadzki, J.V.2
  • 21
    • 0024469934 scopus 로고
    • Depletion of arterial L-arginine causes reversible tolerance to endothelium-dependent relaxation
    • Gold ME, Bush PA, Ignarro LJ (1989). Depletion of arterial L-arginine causes reversible tolerance to endothelium-dependent relaxation. Biochem Biophys Res Commun 164 : 714 721.
    • (1989) Biochem Biophys Res Commun , vol.164 , pp. 714-721
    • Gold, M.E.1    Bush, P.A.2    Ignarro, L.J.3
  • 22
    • 4744365177 scopus 로고    scopus 로고
    • Ischemia-reperfusion selectively impairs nitric oxide-mediated dilation in coronary arterioles: Counteracting role of arginase
    • Hein TW, Zhang C, Wang W, Chang CI, Thengchaisri N, Kuo L (2003). Ischemia-reperfusion selectively impairs nitric oxide-mediated dilation in coronary arterioles: counteracting role of arginase. FASEB J 17 : 2328 2330.
    • (2003) FASEB J , vol.17 , pp. 2328-2330
    • Hein, T.W.1    Zhang, C.2    Wang, W.3    Chang, C.I.4    Thengchaisri, N.5    Kuo, L.6
  • 23
    • 27744592965 scopus 로고    scopus 로고
    • Implications for repetitive application of acetylcholine in the determination of the mechanisms of endothelium-dependent relaxation
    • Hogan M, O'malley KD, Healy J, O'brien S, Bund SJ (2005). Implications for repetitive application of acetylcholine in the determination of the mechanisms of endothelium-dependent relaxation. Vascul Pharmacol 43 : 227 233.
    • (2005) Vascul Pharmacol , vol.43 , pp. 227-233
    • Hogan, M.1    O'Malley, K.D.2    Healy, J.3    O'Brien, S.4    Bund, S.J.5
  • 24
    • 33745449514 scopus 로고    scopus 로고
    • Production of nitric oxide during graft rejection is regulated by the Th1/Th2 balance, the arginase activity, and L-arginine metabolism
    • Holan V, Pindjakova J, Krulova M, Neuwirth A, Fric J, Zajicova A (2006). Production of nitric oxide during graft rejection is regulated by the Th1/Th2 balance, the arginase activity, and L-arginine metabolism. Transplantation 81 : 1708 1715.
    • (2006) Transplantation , vol.81 , pp. 1708-1715
    • Holan, V.1    Pindjakova, J.2    Krulova, M.3    Neuwirth, A.4    Fric, J.5    Zajicova, A.6
  • 25
    • 0001362568 scopus 로고
    • The inhibition of arginase by amino acids
    • Hunter A, Downs DE (1945). The inhibition of arginase by amino acids. J Biol Chem 157 : 427 446.
    • (1945) J Biol Chem , vol.157 , pp. 427-446
    • Hunter, A.1    Downs, D.E.2
  • 26
    • 15544390388 scopus 로고    scopus 로고
    • Arginase inhibition restores arteriolar endothelial function in Dahl rats with salt-induced hypertension
    • Johnson FK, Johnson RA, Peyton KJ, Durante W (2005). Arginase inhibition restores arteriolar endothelial function in Dahl rats with salt-induced hypertension. Am J Physiol Regul Integr Comp Physiol 288 : R1057 R1062.
    • (2005) Am J Physiol Regul Integr Comp Physiol , vol.288
    • Johnson, F.K.1    Johnson, R.A.2    Peyton, K.J.3    Durante, W.4
  • 27
    • 0028907382 scopus 로고
    • Determination of the metal ion separation and energies of the three lowest electronic states of dimanganese (II,II) complexes and enzymes: Catalase and liver arginase
    • Khangulov SV, Pessiki PJ, Barynin VV, Ash DE, Dismukes GC (1995). Determination of the metal ion separation and energies of the three lowest electronic states of dimanganese (II,II) complexes and enzymes: catalase and liver arginase. Biochemistry 34 : 2015 2025.
    • (1995) Biochemistry , vol.34 , pp. 2015-2025
    • Khangulov, S.V.1    Pessiki, P.J.2    Barynin, V.V.3    Ash, D.E.4    Dismukes, G.C.5
  • 28
    • 0035814879 scopus 로고    scopus 로고
    • Probing erectile function: S-(2-boronoethyl)-L-cysteine binds to arginase as a transition state analogue and enhances smooth muscle relaxation in human penile corpus cavernosum
    • Kim NN, Cox JD, Baggio RF, Emig FA, Mistry SK, Harper SL et al. (2001). Probing erectile function: S-(2-boronoethyl)-L-cysteine binds to arginase as a transition state analogue and enhances smooth muscle relaxation in human penile corpus cavernosum. Biochemistry 40 : 2678 2688.
    • (2001) Biochemistry , vol.40 , pp. 2678-2688
    • Kim, N.N.1    Cox, J.D.2    Baggio, R.F.3    Emig, F.A.4    Mistry, S.K.5    Harper, S.L.6
  • 29
    • 0036150672 scopus 로고    scopus 로고
    • Insulin inhibits acetylcholine responses in rat i/ated mesenteric arteries via a non-nitric oxide nonprostanoid pathway
    • Kimura M, Jefferis AM, Watanabe H, Chin-Dusting J (2002). Insulin inhibits acetylcholine responses in rat i/ated mesenteric arteries via a non-nitric oxide nonprostanoid pathway. Hypertension 39 : 35 40.
    • (2002) Hypertension , vol.39 , pp. 35-40
    • Kimura, M.1    Jefferis, A.M.2    Watanabe, H.3    Chin-Dusting, J.4
  • 31
    • 0030905327 scopus 로고    scopus 로고
    • Non-specific inhibition by human lipoproteins of endothelium dependent relaxation in rat aorta may be attributed to lipoprotein phospholipids
    • Lewis TV, Dart AM, Chin-Dusting JP (1997). Non-specific inhibition by human lipoproteins of endothelium dependent relaxation in rat aorta may be attributed to lipoprotein phospholipids. Cardiovasc Res 34 : 590 596.
    • (1997) Cardiovasc Res , vol.34 , pp. 590-596
    • Lewis, T.V.1    Dart, A.M.2    Chin-Dusting, J.P.3
  • 33
    • 20844459470 scopus 로고    scopus 로고
    • Thrombin stimulates human endothelial arginase enzymatic activity via RhoA/ROCK pathway. Implications for atherosclerotic endothelial dysfunction
    • Ming XF, Barandier C, Viswambharan H, Kwak BR, Mach F, Mazzolai L et al. (2004). Thrombin stimulates human endothelial arginase enzymatic activity via RhoA/ROCK pathway. Implications for atherosclerotic endothelial dysfunction. Circ 110 : 3307 3314.
    • (2004) Circ , vol.110 , pp. 3307-3314
    • Ming, X.F.1    Barandier, C.2    Viswambharan, H.3    Kwak, B.R.4    MacH, F.5    Mazzolai, L.6
  • 35
    • 1342346796 scopus 로고    scopus 로고
    • How could aortic arginase activity enhancement be involved in DOCA-salt hypertension?
    • Rodriguez S, Schleiffer R, Raul F, Richert L, Berthelot A (2004). How could aortic arginase activity enhancement be involved in DOCA-salt hypertension? Clin Exp Hypertens 26 : 1 12.
    • (2004) Clin Exp Hypertens , vol.26 , pp. 1-12
    • Rodriguez, S.1    Schleiffer, R.2    Raul, F.3    Richert, L.4    Berthelot, A.5
  • 36
    • 37849019273 scopus 로고    scopus 로고
    • Diabetes-induced coronary vascular dysfunction involves increased arginase activity
    • Romero MJ, Platt DH, Tawfik HE, Labazi M, El-Remessy AB, Bartoli M et al. (2008). Diabetes-induced coronary vascular dysfunction involves increased arginase activity. Circ Res 102 : 95 102.
    • (2008) Circ Res , vol.102 , pp. 95-102
    • Romero, M.J.1    Platt, D.H.2    Tawfik, H.E.3    Labazi, M.4    El-Remessy, A.B.5    Bartoli, M.6
  • 37
    • 33750491292 scopus 로고    scopus 로고
    • Oxidized low-density lipoprotein-dependent endothelial arginase II activation contributes to impaired nitric oxide signaling
    • Ryoo S, Lemmon CA, Soucy KG, Gupta G, White AR, Nyhan D et al. (2006). Oxidized low-density lipoprotein-dependent endothelial arginase II activation contributes to impaired nitric oxide signaling. Circ Res 99 : 951 960.
    • (2006) Circ Res , vol.99 , pp. 951-960
    • Ryoo, S.1    Lemmon, C.A.2    Soucy, K.G.3    Gupta, G.4    White, A.R.5    Nyhan, D.6
  • 38
    • 42549088600 scopus 로고    scopus 로고
    • Endothelial arginase II: A novel target for the treatment of atherosclerosis
    • Ryoo S, Gupta G, Benjo A, Lim HK, Camara A, Sikka G et al. (2008). Endothelial arginase II: a novel target for the treatment of atherosclerosis. Circ Res 102 : 923 932.
    • (2008) Circ Res , vol.102 , pp. 923-932
    • Ryoo, S.1    Gupta, G.2    Benjo, A.3    Lim, H.K.4    Camara, A.5    Sikka, G.6
  • 39
    • 3242787292 scopus 로고    scopus 로고
    • Involvement of increased arginase activity in impaired cavernous relaxation with aging in the rabbit
    • Sakai Y, Masuda H, Kihara K, Kurosaki E, Yamauchi Y, Azuma H (2004). Involvement of increased arginase activity in impaired cavernous relaxation with aging in the rabbit. J Urol 172 : 369 373.
    • (2004) J Urol , vol.172 , pp. 369-373
    • Sakai, Y.1    Masuda, H.2    Kihara, K.3    Kurosaki, E.4    Yamauchi, Y.5    Azuma, H.6
  • 40
    • 34848861137 scopus 로고    scopus 로고
    • Inducible NO synthase dependent S-nitrosylation and activation of arginase1 contribute to age-related endothelial dysfunction
    • Santhanam L, Lim HK, Miriel V, Brown T, Patel M, Balanson S et al. (2007). Inducible NO synthase dependent S-nitrosylation and activation of arginase1 contribute to age-related endothelial dysfunction. Circ Res 101 : 692 702.
    • (2007) Circ Res , vol.101 , pp. 692-702
    • Santhanam, L.1    Lim, H.K.2    Miriel, V.3    Brown, T.4    Patel, M.5    Balanson, S.6
  • 41
    • 0032523112 scopus 로고    scopus 로고
    • Alpha]-Difluoromethylornithine (DFMO) as a potent arginase activity inhibitor in human colon carcinoma cells
    • Selamnia M, Mayeur C, Robert V, Blachier F (1998 alpha]- Difluoromethylornithine (DFMO) as a potent arginase activity inhibitor in human colon carcinoma cells. Biochem Pharmacol 55 : 1241 1245.
    • (1998) Biochem Pharmacol , vol.55 , pp. 1241-1245
    • Selamnia, M.1    Mayeur, C.2    Robert, V.3    Blachier, F.4
  • 42
    • 10544239533 scopus 로고    scopus 로고
    • The importance of the hyperpolarizing mechanism increases as the vessel size decreases in endothelium-dependent relaxations in rat mesenteric circulation
    • Shimokawa H, Yasutake H, Fujii K, Owada MK, Nakaike R, Fukumoto Y et al. (1996). The importance of the hyperpolarizing mechanism increases as the vessel size decreases in endothelium-dependent relaxations in rat mesenteric circulation. J Cardiovasc Pharmacol 28 : 703 711.
    • (1996) J Cardiovasc Pharmacol , vol.28 , pp. 703-711
    • Shimokawa, H.1    Yasutake, H.2    Fujii, K.3    Owada, M.K.4    Nakaike, R.5    Fukumoto, Y.6
  • 43
    • 33645229473 scopus 로고    scopus 로고
    • Arginase modulates myocardial contractility by a nitric oxide synthase 1-dependent mechanism
    • Steppan J, Ryoo S, Schuleri KH, Gregg C, Hasan RK, White AR et al. (2006). Arginase modulates myocardial contractility by a nitric oxide synthase 1-dependent mechanism. Proc Natl Acad Sci USA 103 : 4759 4764.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 4759-4764
    • Steppan, J.1    Ryoo, S.2    Schuleri, K.H.3    Gregg, C.4    Hasan, R.K.5    White, A.R.6
  • 44
    • 0033395710 scopus 로고    scopus 로고
    • Effects of the new arginase inhibitor N[omega]-hydroxy-nor-arginine on NO synthase activity in murine macrophages
    • Tenu J-P, Lepoivre M, Moali C, Brollo M, Mansuy D, Boucher J-L (1999). Effects of the new arginase inhibitor N[omega]-hydroxy-nor-arginine on NO synthase activity in murine macrophages. Nitric Oxide 3 : 427 438.
    • (1999) Nitric Oxide , vol.3 , pp. 427-438
    • Tenu, J.-P.1    Lepoivre, M.2    Moali, C.3    Brollo, M.4    Mansuy, D.5    Boucher, J.-L.6
  • 46
    • 0036827761 scopus 로고    scopus 로고
    • Involvement of NO in the endothelium-independent relaxing effects of N(omega)-hydroxy-L-arginine and other compounds bearing a C=NOH function in the rat aorta
    • Vetrovsky P, Boucher JL, Schott C, Beranova P, Chalupsky K, Callizot N et al. (2002). Involvement of NO in the endothelium-independent relaxing effects of N(omega)-hydroxy-L-arginine and other compounds bearing a C=NOH function in the rat aorta. J Pharmacol Exp Ther 303 : 823 830.
    • (2002) J Pharmacol Exp Ther , vol.303 , pp. 823-830
    • Vetrovsky, P.1    Boucher, J.L.2    Schott, C.3    Beranova, P.4    Chalupsky, K.5    Callizot, N.6
  • 47
    • 0025799631 scopus 로고
    • N[omega]-Hydroxy-L-arginine: A novel arginine analog capable of causing vasorelaxation in bovine intrapulmonary artery
    • Wallace GC, Gulati P, Fukuto JM (1991). N[omega]-Hydroxy-L-arginine: a novel arginine analog capable of causing vasorelaxation in bovine intrapulmonary artery. Biochem Biophys Res Commun 176 : 528 534.
    • (1991) Biochem Biophys Res Commun , vol.176 , pp. 528-534
    • Wallace, G.C.1    Gulati, P.2    Fukuto, J.M.3
  • 48
    • 0027281127 scopus 로고
    • Different responses to acetylcholine in the presence of nitric oxide inhibitor in rat aortae and mesenteric arteries
    • Wu CC, Chen SJ, Yen MH (1993). Different responses to acetylcholine in the presence of nitric oxide inhibitor in rat aortae and mesenteric arteries. Clin Exp Pharmacol Physiol 20 : 405 412.
    • (1993) Clin Exp Pharmacol Physiol , vol.20 , pp. 405-412
    • Wu, C.C.1    Chen, S.J.2    Yen, M.H.3
  • 49
    • 9444220218 scopus 로고    scopus 로고
    • Increased arginase II and decreased NO synthesis in endothelial cells of patients with pulmonary arterial hypertension
    • Xu W, Kaneko FT, Zheng S, Comhair SA, Janocha AJ, Goggans T et al. (2004). Increased arginase II and decreased NO synthesis in endothelial cells of patients with pulmonary arterial hypertension. FASEB J 18 : 1746 1748.
    • (2004) FASEB J , vol.18 , pp. 1746-1748
    • Xu, W.1    Kaneko, F.T.2    Zheng, S.3    Comhair, S.A.4    Janocha, A.J.5    Goggans, T.6
  • 50
    • 0035347173 scopus 로고    scopus 로고
    • Constitutive expression of arginase in microvascular endothelial cells counteracts nitric oxide-mediated vasodilatory function
    • Zhang C, Hein TW, Wang W, Chang CI, Kuo L (2001). Constitutive expression of arginase in microvascular endothelial cells counteracts nitric oxide-mediated vasodilatory function. FASEB J 15 : 1264 1266.
    • (2001) FASEB J , vol.15 , pp. 1264-1266
    • Zhang, C.1    Hein, T.W.2    Wang, W.3    Chang, C.I.4    Kuo, L.5
  • 51
    • 9644282852 scopus 로고    scopus 로고
    • Upregulation of vascular arginase in hypertension decreases nitric oxide-mediated dilation of coronary arterioles
    • Zhang C, Hein TW, Wang W, Miller MW, Fossum TW, Mcdonald MM et al. (2004). Upregulation of vascular arginase in hypertension decreases nitric oxide-mediated dilation of coronary arterioles. Hypertension 44 : 935 943.
    • (2004) Hypertension , vol.44 , pp. 935-943
    • Zhang, C.1    Hein, T.W.2    Wang, W.3    Miller, M.W.4    Fossum, T.W.5    McDonald, M.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.