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Volumn 111, Issue 6, 2008, Pages 2962-2972

Multiple myeloma

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; BENCE JONES PROTEIN; BORTEZOMIB; CARMUSTINE; CORTICOSTEROID; CYCLOPHOSPHAMIDE; DEXAMETHASONE; DISTARAL; DOXORUBICIN; LENALIDOMIDE; MELPHALAN; NEUROSEDYN; PAMIDRONIC ACID; PLACEBO; PREDNISONE; PROTEASOME; QUININE; SERUM GLOBULIN; STEROID; THALIDOMIDE; UBIQUITIN; UNCLASSIFIED DRUG; VINCRISTINE; TUMOR MARKER;

EID: 42449114035     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2007-10-078022     Document Type: Review
Times cited : (744)

References (101)
  • 2
    • 61849118840 scopus 로고    scopus 로고
    • Plasma cell disorders
    • Goldman L, Ausiello D. eds, 23rd ed. Philadelphia. PA: Saunders;
    • Rajkumar SV, Kyle RA. Plasma cell disorders. In: Goldman L, Ausiello D. eds. Cecil Textbook of Medicine, 23rd ed. Philadelphia. PA: Saunders; 2007;1426-1437.
    • (2007) Cecil Textbook of Medicine , pp. 1426-1437
    • Rajkumar, S.V.1    Kyle, R.A.2
  • 3
    • 0037148921 scopus 로고    scopus 로고
    • A long-term study of prognosis of monoclonal gammopathy of undetermined significance
    • Kyle RA, Therneau TM, Rajkumar SV. et al. A long-term study of prognosis of monoclonal gammopathy of undetermined significance. N Engl J Med. 2002;346:564-569.
    • (2002) N Engl J Med , vol.346 , pp. 564-569
    • Kyle, R.A.1    Therneau, T.M.2    Rajkumar, S.V.3
  • 4
    • 33645416095 scopus 로고    scopus 로고
    • Prevalence of monoclonal gammopathy of undetermined significance
    • Kyle RA, Therneau TM, Rajkumar SV, et al. Prevalence of monoclonal gammopathy of undetermined significance. N Engl J Med. 2006;354: 1362-1369.
    • (2006) N Engl J Med , vol.354 , pp. 1362-1369
    • Kyle, R.A.1    Therneau, T.M.2    Rajkumar, S.V.3
  • 5
    • 34250694807 scopus 로고    scopus 로고
    • Clinical course and prognosis of smoldering (asymptomatic) multiple myeloma
    • Kyle RA, Remstein ED, Therneau TM, et al. Clinical course and prognosis of smoldering (asymptomatic) multiple myeloma. N Engl J Med. 2007; 356:2582-2590.
    • (2007) N Engl J Med , vol.356 , pp. 2582-2590
    • Kyle, R.A.1    Remstein, E.D.2    Therneau, T.M.3
  • 7
    • 0000364822 scopus 로고
    • Remarks on the pathology of mollities ossium with cases
    • Solly S. Remarks on the pathology of mollities ossium with cases. Med ChirTrans Lond. 1844; 27:435-461.
    • (1844) Med ChirTrans Lond , vol.27 , pp. 435-461
    • Solly, S.1
  • 8
    • 0000738998 scopus 로고
    • Case of mollities and fragilitas ossium, accompanied with urine strongly charged with animal matter
    • Macintyre W. Case of mollities and fragilitas ossium, accompanied with urine strongly charged with animal matter. Med ChirTrans Lond. 1850; 33:211-232.
    • (1850) Med ChirTrans Lond , vol.33 , pp. 211-232
    • Macintyre, W.1
  • 9
    • 0034487698 scopus 로고    scopus 로고
    • Multiple myeloma: An odyssey of discovery
    • Kyle RA. Multiple myeloma: an odyssey of discovery. BrJ Haematol. 2000;111:1035-1044.
    • (2000) BrJ Haematol , vol.111 , pp. 1035-1044
    • Kyle, R.A.1
  • 10
    • 0001959377 scopus 로고
    • Chemical pathology
    • Bence Jones H. Chemical pathology. Lancet 1847;2:88-92.
    • (1847) Lancet , vol.2 , pp. 88-92
    • Bence Jones, H.1
  • 11
    • 0002448054 scopus 로고
    • On the new substance occurring in thein the urine of a patient with mollities ossium
    • Bence Jones H. On the new substance occurring in thein the urine of a patient with mollities ossium. Philos Trans R Soc Lond. 1848;138:55-62.
    • (1848) Philos Trans R Soc Lond , vol.138 , pp. 55-62
    • Bence Jones, H.1
  • 12
    • 0000820199 scopus 로고
    • Ueber bindegewebszellen
    • Waldeyer W. Ueber bindegewebszellen. Arch Microbiol Anat. 1875;11:176-194.
    • (1875) Arch Microbiol Anat , vol.11 , pp. 176-194
    • Waldeyer, W.1
  • 13
    • 0006221360 scopus 로고
    • A case of multiple myeloma
    • Wright JH. A case of multiple myeloma. Trans Assoc Am Phys. 1900;15:137-147.
    • (1900) Trans Assoc Am Phys , vol.15 , pp. 137-147
    • Wright, J.H.1
  • 14
    • 0006260451 scopus 로고
    • Die intravitale Untersuchungsmethodik des Knochenmarks.
    • Arinkin MI. Die intravitale Untersuchungsmethodik des Knochenmarks. Folia Haematol. 1929;38:233-240.
    • (1929) Folia Haematol , vol.38 , pp. 233-240
    • Arinkin, M.I.1
  • 15
    • 0006166461 scopus 로고
    • Value of the sternal puncture in the diagnosis of multiple myeloma
    • Rosenthal N, Vogel P. Value of the sternal puncture in the diagnosis of multiple myeloma. J Mt Sinai Hosp. 1938;4:1001-1019.
    • (1938) J Mt Sinai Hosp , vol.4 , pp. 1001-1019
    • Rosenthal, N.1    Vogel, P.2
  • 17
    • 61849175110 scopus 로고
    • Die mikroscopisch-chemisch-pathologische untersuchung
    • Heller JD. Die mikroscopisch-chemisch-pathologische untersuchung. Vienna: Braumuller and Seidel; 1846.
    • (1846) Vienna: Braumuller and Seidel
    • Heller, J.D.1
  • 18
    • 0006170774 scopus 로고
    • Ueber das Vorkommen des sogenannten Bence Jones' schen Eiweisskorpers im normalen Knochenmark.
    • Fleischer R XXIV. Ueber das Vorkommen des sogenannten Bence Jones' schen Eiweisskorpers im normalen Knochenmark. Arch Pathol Anatom Physiol Klin Med. 1880;80:842-849.
    • (1880) Arch Pathol Anatom Physiol Klin Med , vol.80 , pp. 842-849
    • Fleischer, R.X.1
  • 19
    • 0006262932 scopus 로고
    • Immunological reactions of Bence-Jones proteins: II. Differences between Bence-Jones proteins from various sources
    • Bayne-Jones S, Wilson DW. Immunological reactions of Bence-Jones proteins: II. Differences between Bence-Jones proteins from various sources. Bull Johns Hopkins Hosp. 1922;33:119-125.
    • (1922) Bull Johns Hopkins Hosp , vol.33 , pp. 119-125
    • Bayne-Jones, S.1    Wilson, D.W.2
  • 20
    • 0001071256 scopus 로고
    • Multiple-myeloma proteins III. The antigenic relationship of Bence Jones proteins to normal gamma-globulin and multiple-myeloma serum proteins
    • Korngold L, Lipari R. Multiple-myeloma proteins" III. The antigenic relationship of Bence Jones proteins to normal gamma-globulin and multiple-myeloma serum proteins. Cancer. 1956;9:262-272.
    • (1956) Cancer , vol.9 , pp. 262-272
    • Korngold, L.1    Lipari, R.2
  • 21
    • 73049153504 scopus 로고
    • The nature of Bence-Jones proteins: Chemical similarities to polypeptide chains of myeloma globulins and normal gamma-globulins
    • Edelman GM, Gally JA. The nature of Bence-Jones proteins: chemical similarities to polypeptide chains of myeloma globulins and normal gamma-globulins. J Exp Med. 1962;116:207-227.
    • (1962) J Exp Med , vol.116 , pp. 207-227
    • Edelman, G.M.1    Gally, J.A.2
  • 22
    • 0006253754 scopus 로고
    • Hyperproteinemia associated with multiple myelomas: Report of an unusual case
    • Perlzweig WA, Delrue G, Geschicter C. Hyperproteinemia associated with multiple myelomas: report of an unusual case. JAMA. 1928;90:755-757.
    • (1928) JAMA , vol.90 , pp. 755-757
    • Perlzweig, W.A.1    Delrue, G.2    Geschicter, C.3
  • 23
    • 37049163529 scopus 로고
    • A new apparatus for electrophoretic analysis of colloidal mixtures
    • Tiselius A. A new apparatus for electrophoretic analysis of colloidal mixtures. Trans Faraday Soc. 1937;33:524.
    • (1937) Trans Faraday Soc , vol.33 , pp. 524
    • Tiselius, A.1
  • 24
    • 85001403499 scopus 로고
    • Electrophoretic study of immune sera and purified antibody preparation
    • Tiselius A, Kabat EA. Electrophoretic study of immune sera and purified antibody preparation. J Exp Med. 1939;69:119-131.
    • (1939) J Exp Med , vol.69 , pp. 119-131
    • Tiselius, A.1    Kabat, E.A.2
  • 25
    • 0006238221 scopus 로고
    • Electrophoretic patterns of normal and pathological human blood, serum, and plasma
    • Longsworth LG, Shedlovsky T, MacInnes DA. Electrophoretic patterns of normal and pathological human blood, serum, and plasma. J Exp Med. 1939;70:399-413.
    • (1939) J Exp Med , vol.70 , pp. 399-413
    • Longsworth, L.G.1    Shedlovsky, T.2    MacInnes, D.A.3
  • 26
    • 0002171553 scopus 로고
    • Electrophoresis of proteins on filter paper
    • Kunkel HG, Tiselius A. Electrophoresis of proteins on filter paper. J Gen Physiol. 1951;35:89-118.
    • (1951) J Gen Physiol , vol.35 , pp. 89-118
    • Kunkel, H.G.1    Tiselius, A.2
  • 27
    • 50449138086 scopus 로고
    • Methode permettant l'etude conjuguee des proprietes electrophoretiques et immunochimiques d'un melange de proteines; application au serum sanguin.
    • Grabar P, Williams CA. Methode permettant l'etude conjuguee des proprietes electrophoretiques et immunochimiques d'un melange de proteines; application au serum sanguin. Biochim Biophys Acta. 1953;10:193-194.
    • (1953) Biochim Biophys Acta , vol.10 , pp. 193-194
    • Grabar, P.1    Williams, C.A.2
  • 28
    • 0000144001 scopus 로고
    • Direct immunoelectrophoresis
    • Wilson AT. Direct immunoelectrophoresis. J Immunol. 1964;92:431-434.
    • (1964) J Immunol , vol.92 , pp. 431-434
    • Wilson, A.T.1
  • 29
    • 72849156982 scopus 로고
    • Studies on conditions associated with disturbed gamma globulin formation (gammopathies)
    • Waldenström J. Studies on conditions associated with disturbed gamma globulin formation (gammopathies). Harvey Lect. 1961;56:211-231.
    • (1961) Harvey Lect , vol.56 , pp. 211-231
    • Waldenström, J.1
  • 30
    • 0017813724 scopus 로고
    • Monoclonal gammopathy of undetermined significance: Natural history in 241 cases
    • Kyle RA. Monoclonal gammopathy of undetermined significance: natural history in 241 cases. Am J Med. 1978;64:814-826.
    • (1978) Am J Med , vol.64 , pp. 814-826
    • Kyle, R.A.1
  • 31
    • 0000197869 scopus 로고
    • Urethane and stilbamidine in multiple myeloma: Report on two cases
    • Alwall N. Urethane and stilbamidine in multiple myeloma: report on two cases. Lancet. 1947;2: 388-389.
    • (1947) Lancet , vol.2 , pp. 388-389
    • Alwall, N.1
  • 32
    • 0013889899 scopus 로고
    • A controlled trial of urethane treatment in multiple myeloma
    • Holland JR, Hosley H, Scharlau C, et al. A controlled trial of urethane treatment in multiple myeloma. Blood. 1966;27:328-342.
    • (1966) Blood , vol.27 , pp. 328-342
    • Holland, J.R.1    Hosley, H.2    Scharlau, C.3
  • 34
    • 31344444514 scopus 로고
    • Evaluation of new chemotherapeutic agents in the treatment of multiple myeloma: IV. L-Phenylalanine mustard (NSC-8806)
    • Bergsagel DE, Sprague CC, Austin C, Griffith KM. Evaluation of new chemotherapeutic agents in the treatment of multiple myeloma: IV. L-Phenylalanine mustard (NSC-8806). Cancer Chemother Rep. 1962;21:87-99.
    • (1962) Cancer Chemother Rep , vol.21 , pp. 87-99
    • Bergsagel, D.E.1    Sprague, C.C.2    Austin, C.3    Griffith, K.M.4
  • 36
    • 12644304424 scopus 로고
    • A comparison of the effect of prednisone and a placebo in the treatment of multiple myeloma
    • Maas RE. A comparison of the effect of prednisone and a placebo in the treatment of multiple myeloma. Cancer Chemother Rep. 1962;16:257-259.
    • (1962) Cancer Chemother Rep , vol.16 , pp. 257-259
    • Maas, R.E.1
  • 37
    • 0014098383 scopus 로고
    • Intermittent high-dose prednisone (NSC-10023) therapy for multiple myeloma
    • Salmon SE, Shadduck RK, Schilling A. Intermittent high-dose prednisone (NSC-10023) therapy for multiple myeloma. Cancer Chemother Rep. 1967;51:179-187.
    • (1967) Cancer Chemother Rep , vol.51 , pp. 179-187
    • Salmon, S.E.1    Shadduck, R.K.2    Schilling, A.3
  • 39
    • 0014661330 scopus 로고
    • Treatment for multiple myeloma: Combination chemotherapy with different melphalan dose regimens
    • Alexanian R, Haut A, Khan AU, et al. Treatment for multiple myeloma: combination chemotherapy with different melphalan dose regimens. JAMA 1969;208:1680-1685.
    • (1969) JAMA , vol.208 , pp. 1680-1685
    • Alexanian, R.1    Haut, A.2    Khan, A.U.3
  • 41
    • 0017763310 scopus 로고
    • Improved survival times in multiple myeloma treated with melphalan, prednisone, cyclophosphamide, vincristine and BCNU: M-2 protocol
    • Case DC Jr, Lee DJ 3rd, Clarkson BD. Improved survival times in multiple myeloma treated with melphalan, prednisone, cyclophosphamide, vincristine and BCNU: M-2 protocol. Am J Med. 1977;63:897-903.
    • (1977) Am J Med , vol.63 , pp. 897-903
    • Case Jr, D.C.1    Lee 3rd, D.J.2    Clarkson, B.D.3
  • 42
    • 0344076348 scopus 로고    scopus 로고
    • Combination chemotherapy vs melphalan plus prednisone as treatment for multiple myeloma: An overview of 6633 patients from 27 randomized trials
    • Myeloma Trialists' Collaborative Group
    • Myeloma Trialists' Collaborative Group. Combination chemotherapy vs melphalan plus prednisone as treatment for multiple myeloma: an overview of 6633 patients from 27 randomized trials. J Clin Oncol. 1998;16:3832-3842.
    • (1998) J Clin Oncol , vol.16 , pp. 3832-3842
  • 43
    • 0000970496 scopus 로고
    • Intravenous infusion of bone marrow in patients receiving radiation and chemotherapy
    • Thomas ED, Lochte HL Jr, Lu WC, Ferrebee JW. Intravenous infusion of bone marrow in patients receiving radiation and chemotherapy. N Engl J Med. 1957;257:491-496.
    • (1957) N Engl J Med , vol.257 , pp. 491-496
    • Thomas, E.D.1    Lochte Jr, H.L.2    Lu, W.C.3    Ferrebee, J.W.4
  • 45
    • 0022578662 scopus 로고
    • Identicaltwin (syngeneic) marrow transplantation for hematologic cancers
    • Fefer A, Cheever MA, Greenberg PD. Identicaltwin (syngeneic) marrow transplantation for hematologic cancers. J Natl Cancer Inst. 1986;76: 1269-1273.
    • (1986) J Natl Cancer Inst , vol.76 , pp. 1269-1273
    • Fefer, A.1    Cheever, M.A.2    Greenberg, P.D.3
  • 46
    • 0023216770 scopus 로고
    • Bone marrow transplantation in multiple myeloma: Report from the European Cooperative Group for Bone Marrow Transplantation
    • Gahrton G, Tura S, Flesch M, et al. Bone marrow transplantation in multiple myeloma: report from the European Cooperative Group for Bone Marrow Transplantation. Blood. 1987;69:1262-1264.
    • (1987) Blood , vol.69 , pp. 1262-1264
    • Gahrton, G.1    Tura, S.2    Flesch, M.3
  • 47
    • 0020578180 scopus 로고
    • High-dose intravenous melphalan for plasma-cell leukaemia and myeloma
    • McElwain TJ, Powles RL. High-dose intravenous melphalan for plasma-cell leukaemia and myeloma. Lancet. 1983;2:822-824.
    • (1983) Lancet , vol.2 , pp. 822-824
    • McElwain, T.J.1    Powles, R.L.2
  • 48
    • 85047693579 scopus 로고
    • Multiple myeloma treated with high dose intravenous melphalan
    • Selby PJ, McElwain TJ, Nandi AC, et al. Multiple myeloma treated with high dose intravenous melphalan. Br J Haematol. 1987;66:55-62.
    • (1987) Br J Haematol , vol.66 , pp. 55-62
    • Selby, P.J.1    McElwain, T.J.2    Nandi, A.C.3
  • 49
    • 0023552805 scopus 로고
    • Highdose chemoradiotherapy and autologous bone marrow transplantation for resistant multiple myeloma
    • Barlogie B, Alexanian R, Dicke KA, et al. Highdose chemoradiotherapy and autologous bone marrow transplantation for resistant multiple myeloma. Blood. 1987;70:869-872.
    • (1987) Blood , vol.70 , pp. 869-872
    • Barlogie, B.1    Alexanian, R.2    Dicke, K.A.3
  • 50
    • 0032748385 scopus 로고    scopus 로고
    • Antitumor activity of thalidomide in refractory multiple myeloma [see comments]
    • Singhal S, Mehta J, Desikan R, et al. Antitumor activity of thalidomide in refractory multiple myeloma [see comments]. N Engl J Med. 1999;341: 1565-1571.
    • (1999) N Engl J Med , vol.341 , pp. 1565-1571
    • Singhal, S.1    Mehta, J.2    Desikan, R.3
  • 51
    • 0037973279 scopus 로고    scopus 로고
    • A phase 2 study of bortezomib in relapsed, refractory myeloma
    • Richardson PG, Barlogie B, Berenson J, et al. A phase 2 study of bortezomib in relapsed, refractory myeloma. N Engl J Med. 2003;348:2609-2617.
    • (2003) N Engl J Med , vol.348 , pp. 2609-2617
    • Richardson, P.G.1    Barlogie, B.2    Berenson, J.3
  • 52
    • 20444433230 scopus 로고    scopus 로고
    • Bortezomib or high-dose dexamethasone for relapsed multiple myeloma [see Comment]
    • Richardson PG, Sonneveld P, Schuster MW, et al. Bortezomib or high-dose dexamethasone for relapsed multiple myeloma [see Comment]. N Engl J Med. 2005;352:2487-2498.
    • (2005) N Engl J Med , vol.352 , pp. 2487-2498
    • Richardson, P.G.1    Sonneveld, P.2    Schuster, M.W.3
  • 53
    • 27744492561 scopus 로고    scopus 로고
    • Combination therapy with lenalidomide plus dexamethasone (Rev/Dex) for newly diagnosed myeloma
    • Rajkumar SV, Hayman SR, Lacy MQ, et al. Combination therapy with lenalidomide plus dexamethasone (Rev/Dex) for newly diagnosed myeloma. Blood. 2005;106:4050-4053.
    • (2005) Blood , vol.106 , pp. 4050-4053
    • Rajkumar, S.V.1    Hayman, S.R.2    Lacy, M.Q.3
  • 54
    • 33750607347 scopus 로고    scopus 로고
    • A randomized phase 2 study of lenalidomide therapy for patients with relapsed or relapsed and refractory multiple myeloma
    • Richardson PG, Blood E, Mitsiades CS, et al. A randomized phase 2 study of lenalidomide therapy for patients with relapsed or relapsed and refractory multiple myeloma. Blood. 2006;108: 3458-3464.
    • (2006) Blood , vol.108 , pp. 3458-3464
    • Richardson, P.G.1    Blood, E.2    Mitsiades, C.S.3
  • 55
    • 3042735762 scopus 로고    scopus 로고
    • Thalidomide: Tragic past and promising future
    • Rajkumar SV. Thalidomide: tragic past and promising future. Mayo Clin Proc. 2004;79:899-903.
    • (2004) Mayo Clin Proc , vol.79 , pp. 899-903
    • Rajkumar, S.V.1
  • 56
    • 49749219257 scopus 로고
    • Thalidomide and congenital abnormalities
    • Lenz W. Thalidomide and congenital abnormalities. Lancet. 1962;1:45.
    • (1962) Lancet , vol.1 , pp. 45
    • Lenz, W.1
  • 57
    • 47349113508 scopus 로고
    • Thalidomide and congenital abnormalities
    • McBride WG. Thalidomide and congenital abnormalities. Lancet. 1961;2:1358.
    • (1961) Lancet , vol.2 , pp. 1358
    • McBride, W.G.1
  • 58
    • 0004043605 scopus 로고
    • Thalidomide
    • Woodyatt PB. Thalidomide. Lancet. 1962;1:750.
    • (1962) Lancet , vol.1 , pp. 750
    • Woodyatt, P.B.1
  • 59
    • 84883832143 scopus 로고
    • Clinical experience with thalidomide in patients with cancer
    • Grabstad H, Golbey R. Clinical experience with thalidomide in patients with cancer. Clin Pharmacol Ther. 1965;6:298-302.
    • (1965) Clin Pharmacol Ther , vol.6 , pp. 298-302
    • Grabstad, H.1    Golbey, R.2
  • 62
    • 0642276742 scopus 로고    scopus 로고
    • Treatment of plasma cell dyscrasias with thalidomide and its derivatives
    • Dimopoulos MA, Anagnostopoulos A, Weber D. Treatment of plasma cell dyscrasias with thalidomide and its derivatives. J Clin Oncol. 2003;21: 4444-4454.
    • (2003) J Clin Oncol , vol.21 , pp. 4444-4454
    • Dimopoulos, M.A.1    Anagnostopoulos, A.2    Weber, D.3
  • 63
    • 0028018268 scopus 로고
    • The ubiquitin-proteasome proteolytic pathway
    • Ciechanover A. The ubiquitin-proteasome proteolytic pathway. Cell. 1994;79:13-21.
    • (1994) Cell , vol.79 , pp. 13-21
    • Ciechanover, A.1
  • 64
    • 0033152760 scopus 로고    scopus 로고
    • Proteasome inhibitors: A novel class of potent and effective antitumor agents
    • Adams J, Palombella VJ, Sausville EA, et al. Proteasome inhibitors: a novel class of potent and effective antitumor agents. Cancer Res. 1999;59: 2615-2622.
    • (1999) Cancer Res , vol.59 , pp. 2615-2622
    • Adams, J.1    Palombella, V.J.2    Sausville, E.A.3
  • 65
    • 0032189685 scopus 로고    scopus 로고
    • Tumor growth inhibition induced in a murine model of human Burkitt's lymphoma by a proteasome inhibitor
    • Orlowski RZ, Eswara JR, Lafond-Walker A, Grever MR, Orlowski M, Dang CV. Tumor growth inhibition induced in a murine model of human Burkitt's lymphoma by a proteasome inhibitor. Cancer Res. 1998;58:4342-4348.
    • (1998) Cancer Res , vol.58 , pp. 4342-4348
    • Orlowski, R.Z.1    Eswara, J.R.2    Lafond-Walker, A.3    Grever, M.R.4    Orlowski, M.5    Dang, C.V.6
  • 66
    • 0037111832 scopus 로고    scopus 로고
    • Phase I trial of the proteasome inhibitor PS-341 in patients with refractory hematologic malignancles
    • Orlowski RZ, Stinchcombe TE, Mitchell BS, et al. Phase I trial of the proteasome inhibitor PS-341 in patients with refractory hematologic malignancles. J Clin Oncol. 2002;20:4420-4427.
    • (2002) J Clin Oncol , vol.20 , pp. 4420-4427
    • Orlowski, R.Z.1    Stinchcombe, T.E.2    Mitchell, B.S.3
  • 67
    • 0019195859 scopus 로고
    • Cation-sensitive neutral endopeptidase: Isolation and specificity of the bovine pituitary enzyme
    • Wilk S, Orlowski M. Cation-sensitive neutral endopeptidase: isolation and specificity of the bovine pituitary enzyme. J Neurochem. 1980;35: 1172-1182.
    • (1980) J Neurochem , vol.35 , pp. 1172-1182
    • Wilk, S.1    Orlowski, M.2
  • 68
    • 0020615453 scopus 로고
    • Inhibition of rabbit brain prolyl endopeptidase by n-benzyloxycarbonyl-prolylprolinal, a transition state aldehyde inhibitor
    • Wilk S, Orlowski M. Inhibition of rabbit brain prolyl endopeptidase by n-benzyloxycarbonyl-prolylprolinal, a transition state aldehyde inhibitor. J Neurochem. 1983;41:69-75.
    • (1983) J Neurochem , vol.41 , pp. 69-75
    • Wilk, S.1    Orlowski, M.2
  • 69
    • 0035300479 scopus 로고    scopus 로고
    • The proteasome inhibitor PS-341 inhibits growth, induces apoptosis, and overcomes drug resistance in human multiple myeloma cells
    • Hideshima T, Richardson P, Chauhan D, et al. The proteasome inhibitor PS-341 inhibits growth, induces apoptosis, and overcomes drug resistance in human multiple myeloma cells. Cancer Res. 2001;61:3071-3076.
    • (2001) Cancer Res , vol.61 , pp. 3071-3076
    • Hideshima, T.1    Richardson, P.2    Chauhan, D.3
  • 70
    • 34548539381 scopus 로고    scopus 로고
    • Randomized Phase III study of pegylated liposomal doxorubicin plus bortezomib compared with bortezomib alone in relapsed or refractory multiple myeloma: Combination therapy improves time to progression
    • Orlowski RZ, Nagler A, Sonneveld P, et al. Randomized Phase III study of pegylated liposomal doxorubicin plus bortezomib compared with bortezomib alone in relapsed or refractory multiple myeloma: combination therapy improves time to progression. J Clin Oncol. 2007;25:3892-3901.
    • (2007) J Clin Oncol , vol.25 , pp. 3892-3901
    • Orlowski, R.Z.1    Nagler, A.2    Sonneveld, P.3
  • 71
    • 0036839013 scopus 로고    scopus 로고
    • Immunomodulatory drug CC-5013 overcomes drug resistance and is well tolerated in patients with relapsed multiple myeloma
    • Richardson PG, Schlossman RL, Weller E, et al. Immunomodulatory drug CC-5013 overcomes drug resistance and is well tolerated in patients with relapsed multiple myeloma. Blood. 2002; 100:3063-3067.
    • (2002) Blood , vol.100 , pp. 3063-3067
    • Richardson, P.G.1    Schlossman, R.L.2    Weller, E.3
  • 72
    • 36349023319 scopus 로고    scopus 로고
    • Lenalidomide plus dexamethasone for relapsed or refractory multiple myeloma
    • Dimopoulos M, Spencer A, Attal M, et al. Lenalidomide plus dexamethasone for relapsed or refractory multiple myeloma. N Engl J Med. 2007; 357:2123-2132.
    • (2007) N Engl J Med , vol.357 , pp. 2123-2132
    • Dimopoulos, M.1    Spencer, A.2    Attal, M.3
  • 73
    • 36349010285 scopus 로고    scopus 로고
    • Lenalidomide plus dexamethasone for relapsed multiple myeloma in North America
    • Weber DM, Chen C, Niesvizky R, et al. Lenalidomide plus dexamethasone for relapsed multiple myeloma in North America. N Engl J Med. 2007; 357:2133-2142.
    • (2007) N Engl J Med , vol.357 , pp. 2133-2142
    • Weber, D.M.1    Chen, C.2    Niesvizky, R.3
  • 74
    • 0016804136 scopus 로고
    • A clinical staging system for multiple myeloma: Correlation of measured myeloma cell mass with presenting clinical features, response to treatment, and survival
    • Durie BG, Salmon SE. A clinical staging system for multiple myeloma: correlation of measured myeloma cell mass with presenting clinical features, response to treatment, and survival. Cancer. 1975;36:842-854.
    • (1975) Cancer , vol.36 , pp. 842-854
    • Durie, B.G.1    Salmon, S.E.2
  • 75
    • 20644460600 scopus 로고    scopus 로고
    • International staging system for multiple myeloma
    • Greipp PR, San Miguel JF, Durie BG, et al. International staging system for multiple myeloma. J Clin Oncol. 2005;23:3412-3420.
    • (2005) J Clin Oncol , vol.23 , pp. 3412-3420
    • Greipp, P.R.1    San Miguel, J.F.2    Durie, B.G.3
  • 76
    • 33847369790 scopus 로고    scopus 로고
    • Treatment of newly diagnosed multiple myeloma based on Mayo stratification of myeloma and riskadapted therapy (mSMART): Consensus Statement
    • Dispenzieri A, Rajkumar SV, Gertz MA, et al. Treatment of newly diagnosed multiple myeloma based on Mayo stratification of myeloma and riskadapted therapy (mSMART): Consensus Statement. Mayo Clin Proc. 2007;82:323-341.
    • (2007) Mayo Clin Proc , vol.82 , pp. 323-341
    • Dispenzieri, A.1    Rajkumar, S.V.2    Gertz, M.A.3
  • 77
    • 8944220233 scopus 로고    scopus 로고
    • A prospective, randomized trial of autologous bone marrow transplantation and chemotherapy in multiple myeloma: Intergroupe Francais du Myelome
    • Attal M, Harousseau JL, StoppaAM, et al. A prospective, randomized trial of autologous bone marrow transplantation and chemotherapy in multiple myeloma: Intergroupe Francais du Myelome. N Engl J Med. 1996;335:91-97.
    • (1996) N Engl J Med , vol.335 , pp. 91-97
    • Attal, M.1    Harousseau, J.L.2    StoppaAM3
  • 78
    • 0037739753 scopus 로고    scopus 로고
    • High-dose chemotherapy with hematopoietic stem-cell rescue for multiple myeloma
    • Child JA. Morgan GJ. Davies FE. et al. High-dose chemotherapy with hematopoietic stem-cell rescue for multiple myeloma. N Engl J Med. 2003; 348:1875-1883.
    • (2003) N Engl J Med , vol.348 , pp. 1875-1883
    • Child, J.A.1    Morgan, G.J.2    Davies, F.E.3
  • 79
    • 0032211193 scopus 로고    scopus 로고
    • Highdose therapy and autologous peripheral blood stem cell transplantation in multiple myeloma: Up-front or rescue treatment? Results of a multicenter sequential randomized clinical trial
    • Fermand JP, Ravaud P. Chevret S. et al. Highdose therapy and autologous peripheral blood stem cell transplantation in multiple myeloma: up-front or rescue treatment? Results of a multicenter sequential randomized clinical trial. Blood. 1998;92:3131-3136.
    • (1998) Blood , vol.92 , pp. 3131-3136
    • Fermand, J.P.1    Ravaud, P.2    Chevret, S.3
  • 80
    • 33644920953 scopus 로고    scopus 로고
    • Standard chemotherapy compared with high-dose chemoradiotherapy for multiple myeloma: Final results of phase III US Intergroup Trial S9321
    • Barlogie B. Kyle RA, Anderson KC, et al. Standard chemotherapy compared with high-dose chemoradiotherapy for multiple myeloma: final results of phase III US Intergroup Trial S9321. J Clin Oncol. 2006;24:929-936.
    • (2006) J Clin Oncol , vol.24 , pp. 929-936
    • Barlogie, B.1    Kyle, R.A.2    Anderson, K.C.3
  • 81
    • 0347815503 scopus 로고    scopus 로고
    • Single vs double autologous stem-cell transplantation for multiple myeloma [see comment]
    • Attal M, Harousseau JL. Facon T, et al. Single vs double autologous stem-cell transplantation for multiple myeloma [see comment]. N Engl J Med. 2003;349:2495-2502.
    • (2003) N Engl J Med , vol.349 , pp. 2495-2502
    • Attal, M.1    Harousseau, J.L.2    Facon, T.3
  • 82
    • 28444494386 scopus 로고    scopus 로고
    • High-dose therapy intensification compared with continued standard chemotherapy in multiple myeloma patients responding to the initial chemotherapy: Long-term results from a prospective randomized trial from the Spanish cooperative group PETHEMA
    • Blade J, Rosinol L, Sureda A. et al. High-dose therapy intensification compared with continued standard chemotherapy in multiple myeloma patients responding to the initial chemotherapy: long-term results from a prospective randomized trial from the Spanish cooperative group PETHEMA. Blood. 2005;106:3755-3759.
    • (2005) Blood , vol.106 , pp. 3755-3759
    • Blade, J.1    Rosinol, L.2    Sureda, A.3
  • 83
    • 33947197286 scopus 로고    scopus 로고
    • A comparison of allografting with autografting for newly diagnosed myeloma
    • Bruno B. Rotta M. Patriarca F, et al. A comparison of allografting with autografting for newly diagnosed myeloma. N Engl J Med. 2007;356:1110-1120.
    • (2007) N Engl J Med , vol.356 , pp. 1110-1120
    • Bruno, B.1    Rotta, M.2    Patriarca, F.3
  • 84
    • 33644843725 scopus 로고    scopus 로고
    • Oral melphalan and prednisone chemotherapy plus thalidomide compared with melphalan and prednisone alone in elderly patients with multiple myeloma: Randomised controlled trial
    • Palumbo A, Bringhen S, Caravita T, et al. Oral melphalan and prednisone chemotherapy plus thalidomide compared with melphalan and prednisone alone in elderly patients with multiple myeloma: randomised controlled trial. Lancet. 2006; 367:825-831.
    • (2006) Lancet , vol.367 , pp. 825-831
    • Palumbo, A.1    Bringhen, S.2    Caravita, T.3
  • 85
    • 34848833957 scopus 로고    scopus 로고
    • Melphalan and prednisone plus thalidomide vs melphalan and prednisone alone or reduced-intensity autologous stem cell transplantation in elderly patients with multiple myeloma (IFM 99-06): A randomised trial
    • Facon T. Mary JY, Hulin C, et al. Melphalan and prednisone plus thalidomide vs melphalan and prednisone alone or reduced-intensity autologous stem cell transplantation in elderly patients with multiple myeloma (IFM 99-06): a randomised trial. Lancet. 2007;370:1209-1218.
    • (2007) Lancet , vol.370 , pp. 1209-1218
    • Facon, T.1    Mary, J.Y.2    Hulin, C.3
  • 86
    • 0025064260 scopus 로고
    • VAD-based regimens as primary treatment for multiple myeloma
    • Alexanian R. Barlogie B. Tucker S. VAD-based regimens as primary treatment for multiple myeloma. Am J Hematol. 1990;33:86-89.
    • (1990) Am J Hematol , vol.33 , pp. 86-89
    • Alexanian, R.1    Barlogie, B.2    Tucker, S.3
  • 87
    • 33644831033 scopus 로고    scopus 로고
    • Phase III clinical trial of thalidomide plus dexamethasone compared with dexamethasone alone in newly diagnosed multiple myeloma: A clinical trial coordinated by the Eastern Cooperative Oncology Group
    • Rajkumar SV, Blood E, Vesole DH, Fonseca R, Greipp PR. Phase III clinical trial of thalidomide plus dexamethasone compared with dexamethasone alone in newly diagnosed multiple myeloma: a clinical trial coordinated by the Eastern Cooperative Oncology Group. J Clin Oncol. 2006;24:431-436.
    • (2006) J Clin Oncol , vol.24 , pp. 431-436
    • Rajkumar, S.V.1    Blood, E.2    Vesole, D.H.3    Fonseca, R.4    Greipp, P.R.5
  • 88
    • 35448981539 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled trial of thalidomide plus dexamethasone vs dexamethasone alone as primary therapy for newly diagnosed multiple myeloma [abstract]
    • Rajkumar SV, Hussein M. Catalano J. et al. A randomized, double-blind, placebo-controlled trial of thalidomide plus dexamethasone vs dexamethasone alone as primary therapy for newly diagnosed multiple myeloma [abstract]. Blood. 2006; 108:795.
    • (2006) Blood , vol.108 , pp. 795
    • Rajkumar, S.V.1    Hussein, M.2    Catalano, J.3
  • 89
    • 34848824393 scopus 로고    scopus 로고
    • Longterm results of response to therapy, time to progression, and survival with lenalidomide plus dexamethasone in newly diagnosed myeloma
    • Lacy MQ, Gertz MA, Dispenzieri AA, et al. Longterm results of response to therapy, time to progression, and survival with lenalidomide plus dexamethasone in newly diagnosed myeloma. Mayo Clin Proc. 2007;82:1179-1184.
    • (2007) Mayo Clin Proc , vol.82 , pp. 1179-1184
    • Lacy, M.Q.1    Gertz, M.A.2    Dispenzieri, A.A.3
  • 90
    • 34548314992 scopus 로고    scopus 로고
    • Arandomized phase III trial of lenalidomide plus high-dose dexamethasone vs lenalidomide plus low-dose dexamethasone in newly diagnosed multiple myeloma (E4A03): A trial coordinated by the Eastern Cooperative Oncology Group [abstract]
    • Rajkumar SV, Jacobus S, Callander N, Fonseca R, Vesole D, Greipp P. Arandomized phase III trial of lenalidomide plus high-dose dexamethasone vs lenalidomide plus low-dose dexamethasone in newly diagnosed multiple myeloma (E4A03): a trial coordinated by the Eastern Cooperative Oncology Group [abstract]. Blood. 2006; 108:799.
    • (2006) Blood , vol.108 , pp. 799
    • Rajkumar, S.V.1    Jacobus, S.2    Callander, N.3    Fonseca, R.4    Vesole, D.5    Greipp, P.6
  • 91
    • 21344469223 scopus 로고    scopus 로고
    • Bortezomib therapy alone and in combination with dexamethasone for previously untreated symptomatic multiple myeloma
    • Jagannath S, Durie BG, Wolf J, et al. Bortezomib therapy alone and in combination with dexamethasone for previously untreated symptomatic multiple myeloma. Br J Haematol. 2005;129:776-783.
    • (2005) Br J Haematol , vol.129 , pp. 776-783
    • Jagannath, S.1    Durie, B.G.2    Wolf, J.3
  • 92
    • 33750953054 scopus 로고    scopus 로고
    • Bortezomib plus dexamethasone as induction treatment prior to autologous stem cell transplantation in patients with newly diagnosed multiple myeloma: Results of an IFM phase II study
    • Harousseau J, Attal M, Leleu X, et al. Bortezomib plus dexamethasone as induction treatment prior to autologous stem cell transplantation in patients with newly diagnosed multiple myeloma: results of an IFM phase II study. Haematologica. 2006; 91:1498-1505.
    • (2006) Haematologica , vol.91 , pp. 1498-1505
    • Harousseau, J.1    Attal, M.2    Leleu, X.3
  • 93
    • 34548020534 scopus 로고    scopus 로고
    • VELCADE/dexamethasone (Vel/Dex) vs VAD as induction treatment prior to autologous stem cell transplantation (ASCT) in newly diagnosed multiple myeloma (MM): An interim analysis of the IFM 2005-01 Randomized Multicenter Phase III Trial [abstract]
    • Harousseau J-L, Marit G, Caillot D, et al. VELCADE/dexamethasone (Vel/Dex) vs VAD as induction treatment prior to autologous stem cell transplantation (ASCT) in newly diagnosed multiple myeloma (MM): an interim analysis of the IFM 2005-01 Randomized Multicenter Phase III Trial [abstract]. Blood. 2006;108:56.
    • (2006) Blood , vol.108 , pp. 56
    • Harousseau, J.-L.1    Marit, G.2    Caillot, D.3
  • 94
    • 36749094612 scopus 로고    scopus 로고
    • Comparison of melphalan-prednisone- thalidomide (MP-T) to melphalan-prednisone (MP) in patients 75 years of age or older with untreated multiple myeloma (MM). Preliminary results of the randomized, double-blind, placebo controlled IFM 01-01 trial [abstract]
    • Hulin C, Virion J, Leleu X, et al. Comparison of melphalan-prednisone- thalidomide (MP-T) to melphalan-prednisone (MP) in patients 75 years of age or older with untreated multiple myeloma (MM). Preliminary results of the randomized, double-blind, placebo controlled IFM 01-01 trial [abstract], J Clin Oncol. 2007;25:8001.
    • (2007) J Clin Oncol , vol.25 , pp. 8001
    • Hulin, C.1    Virion, J.2    Leleu, X.3
  • 95
    • 33748287079 scopus 로고    scopus 로고
    • Bortezomib plus melphalan and prednisone in elderly untreated patients with multiple myeloma: Results of a multicenter phase 1/2 study
    • Mateos M-V, Hernandez J-M, Hernandez M-T, et al. Bortezomib plus melphalan and prednisone in elderly untreated patients with multiple myeloma: results of a multicenter phase 1/2 study. Blood. 2006;108:2165-2172.
    • (2006) Blood , vol.108 , pp. 2165-2172
    • Mateos, M.-V.1    Hernandez, J.-M.2    Hernandez, M.-T.3
  • 96
    • 35348923502 scopus 로고    scopus 로고
    • Melphalan, prednisone, and lenalidomide treatment for newly diagnosed myeloma: A report from the GIMEMA Italian Multiple Myeloma Network
    • Palumbo A, Falco P, Corradini P, et al. Melphalan, prednisone, and lenalidomide treatment for newly diagnosed myeloma: a report from the GIMEMA Italian Multiple Myeloma Network. J Clin Oncol. 2007;25:4459-4465.
    • (2007) J Clin Oncol , vol.25 , pp. 4459-4465
    • Palumbo, A.1    Falco, P.2    Corradini, P.3
  • 97
    • 34347260711 scopus 로고    scopus 로고
    • Prospective, randomized study of single compared with double autologous stem-cell transplantation for multiple myeloma: Bologna 96 Clinical Study
    • Cavo M, Tosi P, Zamagni E, et al. Prospective, randomized study of single compared with double autologous stem-cell transplantation for multiple myeloma: Bologna 96 Clinical Study. J Clin Oncol. 2007;25:2434-2441.
    • (2007) J Clin Oncol , vol.25 , pp. 2434-2441
    • Cavo, M.1    Tosi, P.2    Zamagni, E.3
  • 98
    • 0142152420 scopus 로고    scopus 로고
    • Allografting with nonmyeloablative conditioning following cytoreductive autografts for the treatment of patients with multiple myeloma
    • Maloney DG, Molina AJ, Sahebi F, et al. Allografting with nonmyeloablative conditioning following cytoreductive autografts for the treatment of patients with multiple myeloma. Blood. 2003;102: 3447-3454.
    • (2003) Blood , vol.102 , pp. 3447-3454
    • Maloney, D.G.1    Molina, A.J.2    Sahebi, F.3
  • 99
    • 33646401089 scopus 로고    scopus 로고
    • Prospective comparison of autologous stem cell transplantation followed by dose-reduced allograft (IFM99-03 trial) with tandem autologous stem cell transplantation (IFM99-04 trial) in high-risk de novo multiple myeloma
    • Garban F, Attal M, Michallet M, et al. Prospective comparison of autologous stem cell transplantation followed by dose-reduced allograft (IFM99-03 trial) with tandem autologous stem cell transplantation (IFM99-04 trial) in high-risk de novo multiple myeloma. Blood. 2006;107:3474-3480.
    • (2006) Blood , vol.107 , pp. 3474-3480
    • Garban, F.1    Attal, M.2    Michallet, M.3
  • 100
    • 33751164196 scopus 로고    scopus 로고
    • Maintenance therapy with thalidomide improves survival in patients with multiple myeloma
    • Attal M, Harousseau J-L, Leyvraz S, et al. Maintenance therapy with thalidomide improves survival in patients with multiple myeloma. Blood. 2006; 108:3289-3294.
    • (2006) Blood , vol.108 , pp. 3289-3294
    • Attal, M.1    Harousseau, J.-L.2    Leyvraz, S.3
  • 101
    • 33847197966 scopus 로고    scopus 로고
    • A practical guide to defining high-risk myeloma for clinical trials, patient counseling and choice of therapy
    • Stewart AK, Bergsagel PL, Greipp PR, et al. A practical guide to defining high-risk myeloma for clinical trials, patient counseling and choice of therapy. Leukemia. 2007;21:529-534.
    • (2007) Leukemia , vol.21 , pp. 529-534
    • Stewart, A.K.1    Bergsagel, P.L.2    Greipp, P.R.3


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