-
1
-
-
0032505102
-
Thrombopoietin
-
Kaushansky K. Thrombopoietin. N Engl J Med. 1998;339:746-754.
-
(1998)
N Engl J Med
, vol.339
, pp. 746-754
-
-
Kaushansky, K.1
-
2
-
-
0032899072
-
The physiological response of thrombopoietin (c-Mpl ligand) to thrombocytopenia in the rat
-
Yang C, Li YC, Kuter DJ. The physiological response of thrombopoietin (c-Mpl ligand) to thrombocytopenia in the rat. Br J Haematol. 1999;105:478-485.
-
(1999)
Br J Haematol
, vol.105
, pp. 478-485
-
-
Yang, C.1
Li, Y.C.2
Kuter, D.J.3
-
3
-
-
0030024685
-
Physiological regulation of early and late stages of megakaryocytopoiesis by thrombopoietin
-
de Sauvage FJ, Carver-Moore K, Luoh SM, et al. Physiological regulation of early and late stages of megakaryocytopoiesis by thrombopoietin. J Exp Med. 1996;183:651-656.
-
(1996)
J Exp Med
, vol.183
, pp. 651-656
-
-
De Sauvage, F.J.1
Carver-Moore, K.2
Luoh, S.M.3
-
5
-
-
0029684417
-
Low levels of erythroid and myeloid progenitors in thrombopoietin- and c-mpl-deficient mice
-
Carver-Moore K, Broxmeyer HE, Luoh SM, et al. Low levels of erythroid and myeloid progenitors in thrombopoietin- and c-mpl-deficient mice. Blood. 1996;88:803-808.
-
(1996)
Blood
, vol.88
, pp. 803-808
-
-
Carver-Moore, K.1
Broxmeyer, H.E.2
Luoh, S.M.3
-
6
-
-
0034085801
-
Future directions with platelet growth factors
-
Kuter DJ. Future directions with platelet growth factors. Semin Hematol. 2000;37:41-49.
-
(2000)
Semin Hematol
, vol.37
, pp. 41-49
-
-
Kuter, D.J.1
-
7
-
-
0034050651
-
Recombinant human thrombopoietin attenuates carboplatin-induced severe thrombocytopenia and the need for platelet transfusions in patients with gynecologic cancer
-
Vadhan-Raj S, Verschraegen CF, Bueso-Ramos C, et al. Recombinant human thrombopoietin attenuates carboplatin-induced severe thrombocytopenia and the need for platelet transfusions in patients with gynecologic cancer. Ann Intern Med. 2000;132:364-368.
-
(2000)
Ann Intern Med
, vol.132
, pp. 364-368
-
-
Vadhan-Raj, S.1
Verschraegen, C.F.2
Bueso-Ramos, C.3
-
8
-
-
0034655649
-
A doubleblind, placebo-controlled trial of pegylated recombinant human megakaryocyte growth and development factor as an adjunct to induction and consolidation therapy for patients with acute myeloid leukemia
-
Schiffer CA, Miller K, Larson RA, et al. A doubleblind, placebo-controlled trial of pegylated recombinant human megakaryocyte growth and development factor as an adjunct to induction and consolidation therapy for patients with acute myeloid leukemia. Blood. 2000;95:2530-2535.
-
(2000)
Blood
, vol.95
, pp. 2530-2535
-
-
Schiffer, C.A.1
Miller, K.2
Larson, R.A.3
-
9
-
-
4243219531
-
Correction of thrombocytopenia and ineffective platelet production in patients infected with human immunodeficiency virus (HIV) by PEG-rHuMGDF therapy
-
Harker LA, Carter RA, Marzec UM, et al. Correction of thrombocytopenia and ineffective platelet production in patients infected with human immunodeficiency virus (HIV) by PEG-rHuMGDF therapy. Blood. 1998;92(suppl 1):707a.
-
(1998)
Blood
, vol.92
, Issue.SUPPL. 1
-
-
Harker, L.A.1
Carter, R.A.2
Marzec, U.M.3
-
10
-
-
0035469813
-
Thrombopoietin therapy increases platelet yields in normal platelet donors
-
Kuter DJ, Goodnough LT, Romo J, et al. Thrombopoietin therapy increases platelet yields in normal platelet donors. Blood. 2001;98:1339-1345.
-
(2001)
Blood
, vol.98
, pp. 1339-1345
-
-
Kuter, D.J.1
Goodnough, L.T.2
Romo, J.3
-
11
-
-
17944389931
-
Randomized, blinded, placebo-controlled phase I trial of pegylated recombinant human megakaryocyte growth and development factor with filgrastim after dose-intensive chemotherapy in patients with advanced cancer
-
Basser RL, Rasko JE, Clarke K, et al. Randomized, blinded, placebo-controlled phase I trial of pegylated recombinant human megakaryocyte growth and development factor with filgrastim after dose-intensive chemotherapy in patients with advanced cancer. Blood. 1997;89:3118-3128.
-
(1997)
Blood
, vol.89
, pp. 3118-3128
-
-
Basser, R.L.1
Rasko, J.E.2
Clarke, K.3
-
12
-
-
0002357056
-
Effect of a single dose of pegylated human recombinant megakaryocyte growth and development factor (PEG-rHuMGDF) on platelet counts: Implications for platelet apheresis
-
Tomita D, Petrarca M, Paine T, Olson K, Roskos L, Cheung E. Effect of a single dose of pegylated human recombinant megakaryocyte growth and development factor (PEG-rHuMGDF) on platelet counts: implications for platelet apheresis. Transfusion. 1997;37:2S.
-
(1997)
Transfusion
, vol.37
-
-
Tomita, D.1
Petrarca, M.2
Paine, T.3
Olson, K.4
Roskos, L.5
Cheung, E.6
-
13
-
-
4243780751
-
A randomized, placebo-controlled, blinded, dose scheduling trial of pegylated recombinant human megakaryocyte growth and development factor (PEG-HUMGDF) with filgrastim support in non-small cell lung cancer (NSCLC) patients treated with paclitaxel and carboplatin during multiple cycles of chemotherapy
-
Crawford J, Glaspy J, Belani C, et al. A randomized, placebo-controlled, blinded, dose scheduling trial of pegylated recombinant human megakaryocyte growth and development factor (PEG-HUMGDF) with filgrastim support in non-small cell lung cancer (NSCLC) patients treated with paclitaxel and carboplatin during multiple cycles of chemotherapy. Proc Am Soc Clin Oncol. 1998;17:73a.
-
(1998)
Proc Am Soc Clin Oncol
, vol.17
-
-
Crawford, J.1
Glaspy, J.2
Belani, C.3
-
14
-
-
0032842829
-
Interaction of thrombopoietin with the platelet c-mpl receptor in plasma: Binding, internalization, stability and pharmacodynamics
-
Li J, Xia Y, Kuter D. Interaction of thrombopoietin with the platelet c-mpl receptor in plasma: binding, internalization, stability and pharmacodynamics. BrJ Haematol. 1999;106:345-356.
-
(1999)
BrJ Haematol
, vol.106
, pp. 345-356
-
-
Li, J.1
Xia, Y.2
Kuter, D.3
-
15
-
-
0033926164
-
Cloning and functional characterization of a novel c-mpl variant expressed in human CD34 cells and platelets
-
Li J, Sabath DF, Kuter DJ. Cloning and functional characterization of a novel c-mpl variant expressed in human CD34 cells and platelets. Cytokine. 2000;12:835-844.
-
(2000)
Cytokine
, vol.12
, pp. 835-844
-
-
Li, J.1
Sabath, D.F.2
Kuter, D.J.3
-
16
-
-
85112396304
-
A prospective cross-sectional study to characterize selected autoimmune (AI) markers and report the incidence of antithrombopoietin antibodies in patients wtih immune thrombocytopenic purpura
-
Bussel J, Aledort L, Hayward C, et al. A prospective cross-sectional study to characterize selected autoimmune (AI) markers and report the incidence of antithrombopoietin antibodies in patients wtih immune thrombocytopenic purpura. Blood. 2000;96:250a.
-
(2000)
Blood
, vol.96
-
-
Bussel, J.1
Aledort, L.2
Hayward, C.3
-
17
-
-
0000416156
-
Characterization of an anti-thrombopoietin antibody that developed in a cancer patient following the injection of PEG-rHuMGDF
-
Li J, Xia Y, Bertino A, Coburn J, Kuter DJ. Characterization of an anti-thrombopoietin antibody that developed in a cancer patient following the injection of PEG-rHuMGDF. Blood. 1999;94:51a.
-
(1999)
Blood
, vol.94
-
-
Li, J.1
Xia, Y.2
Bertino, A.3
Coburn, J.4
Kuter, D.J.5
-
18
-
-
0031877979
-
Thrombopoietin levels after chemotherapy and in naturally occurring human diseases
-
Nichol JL. Thrombopoietin levels after chemotherapy and in naturally occurring human diseases. Curr Opin Hematol. 1998;5:203-208.
-
(1998)
Curr Opin Hematol
, vol.5
, pp. 203-208
-
-
Nichol, J.L.1
-
19
-
-
0034650994
-
Human antibodies with specificity for the C2 domain of factor VIII are derived from VH1 germline genes
-
van Den Brink EN, Turenhout EA, Davies J, et al. Human antibodies with specificity for the C2 domain of factor VIII are derived from VH1 germline genes. Blood. 2000;95:558-563.
-
(2000)
Blood
, vol.95
, pp. 558-563
-
-
Van Den Brink, E.N.1
Turenhout, E.A.2
Davies, J.3
-
21
-
-
0028088531
-
Induction of anti-recombinant human granulocytemacrophage colony-stimulating factor (Escherichia coli-derived) antibodies and clinical effects in nonimmunocompromised patients
-
Ragnhammar P, Friesen HJ, Frodin JE, et al. Induction of anti-recombinant human granulocytemacrophage colony-stimulating factor (Escherichia coli-derived) antibodies and clinical effects in nonimmunocompromised patients. Blood. 1994;84:4078-4087.
-
(1994)
Blood
, vol.84
, pp. 4078-4087
-
-
Ragnhammar, P.1
Friesen, H.J.2
Frodin, J.E.3
-
22
-
-
0030966361
-
Stimulation of megakaryocyte and platelet production by a single dose of recombinant human thrombopoietin in patients with cancer
-
Vadhan-Raj S, Murray LJ, Bueso-Ramos C, et al. Stimulation of megakaryocyte and platelet production by a single dose of recombinant human thrombopoietin in patients with cancer. Ann Intern Med. 1997;126:673-681.
-
(1997)
Ann Intern Med
, vol.126
, pp. 673-681
-
-
Vadhan-Raj, S.1
Murray, L.J.2
Bueso-Ramos, C.3
-
23
-
-
0028117771
-
The purification of megapoietin: A physiological regulator of megakaryocyte growth and platelet production
-
Kuter DJ, Beeler DL, Rosenberg RD. The purification of megapoietin: a physiological regulator of megakaryocyte growth and platelet production. Proc Natl Acad Sci U S A. 1994;91:11104-11108.
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 11104-11108
-
-
Kuter, D.J.1
Beeler, D.L.2
Rosenberg, R.D.3
-
24
-
-
0025884718
-
Erythropoietin titers in health and disease
-
Erslev AJ. Erythropoietin titers in health and disease. Semin Hematol. 1991;28:2-8.
-
(1991)
Semin Hematol
, vol.28
, pp. 2-8
-
-
Erslev, A.J.1
-
25
-
-
0033060985
-
Pure red cell aplasia as presentation of systemic lupus erythematosus: Antibodies to erythropoietin
-
Linardaki GD, Boki KA, Fertakis A, Tzioufas AG. Pure red cell aplasia as presentation of systemic lupus erythematosus: antibodies to erythropoietin. Scand J Rheumatol. 1999;28:189-191.
-
(1999)
Scand J Rheumatol
, vol.28
, pp. 189-191
-
-
Linardaki, G.D.1
Boki, K.A.2
Fertakis, A.3
Tzioufas, A.G.4
-
26
-
-
0030573330
-
Autoantibodies against erythropoietin in a patient with pure redcell aplasia
-
Casadevall N, Dupuy E, Molho-Sabatier P, Tobelem G, Varet B, Mayeux P. Autoantibodies against erythropoietin in a patient with pure redcell aplasia. N Engl J Med. 1996;334:630-633.
-
(1996)
N Engl J Med
, vol.334
, pp. 630-633
-
-
Casadevall, N.1
Dupuy, E.2
Molho-Sabatier, P.3
Tobelem, G.4
Varet, B.5
Mayeux, P.6
-
27
-
-
0029759027
-
Antibodies against recombinant human erythropoietin in a patient with erythropoietin-resistant anemia
-
Peces R, de la Torre M, Alcazar R, Urra JM. Antibodies against recombinant human erythropoietin in a patient with erythropoietin-resistant anemia. N Engl J Med. 1996;335:523-524.
-
(1996)
N Engl J Med
, vol.335
, pp. 523-524
-
-
Peces, R.1
De la Torre, M.2
Alcazar, R.3
Urra, J.M.4
-
28
-
-
0030727797
-
Naturally occurring and therapy-induced antibodies to human granulocyte colony-stimulating factor (G-CSF) in human serum
-
Laricchia-Robbio L, Moscato S, Genua A, Liberati AM, Revoltella RP. Naturally occurring and therapy-induced antibodies to human granulocyte colony-stimulating factor (G-CSF) in human serum. J Cell Physiol. 1997;173:219-226.
-
(1997)
J Cell Physiol
, vol.173
, pp. 219-226
-
-
Laricchia-Robbio, L.1
Moscato, S.2
Genua, A.3
Liberati, A.M.4
Revoltella, R.P.5
-
29
-
-
0032080851
-
Thrombopoietin (TPO) knockout phenotype induced by cross-reactive antibodies against TPO following injection of mice with recombinant adenovirus encoding human TPO
-
Abina MA, Tulliez M, Duffour MT, et al. Thrombopoietin (TPO) knockout phenotype induced by cross-reactive antibodies against TPO following injection of mice with recombinant adenovirus encoding human TPO. J Immunol. 1998;160:4481-4489.
-
(1998)
J Immunol
, vol.160
, pp. 4481-4489
-
-
Abina, M.A.1
Tulliez, M.2
Duffour, M.T.3
-
30
-
-
0030786194
-
Chronic thrombocytopenia is induced in dogs by development of cross-reacting antibodies to the MpL ligand
-
Dale DC, Nichol JL, Rich DA, et al. Chronic thrombocytopenia is induced in dogs by development of cross-reacting antibodies to the MpL ligand. Blood. 1997;90:3456-3461.
-
(1997)
Blood
, vol.90
, pp. 3456-3461
-
-
Dale, D.C.1
Nichol, J.L.2
Rich, D.A.3
-
31
-
-
0034653930
-
Autoantibodies neutralizing thrombopoietin in a patient with amegakaryocytic thrombocytopenic purpura
-
Shiozaki H, Miyawaki S, Kuwaki T, Hagiwara T, Kato T, Miyazaki H. Autoantibodies neutralizing thrombopoietin in a patient with amegakaryocytic thrombocytopenic purpura. Blood. 2000;95:2187-2188.
-
(2000)
Blood
, vol.95
, pp. 2187-2188
-
-
Shiozaki, H.1
Miyawaki, S.2
Kuwaki, T.3
Hagiwara, T.4
Kato, T.5
Miyazaki, H.6
-
32
-
-
0021917016
-
Successful treatment of amegakaryocytic thrombocytopenic purpura with cyclosporine
-
Hill W, Landgraf R. Successful treatment of amegakaryocytic thrombocytopenic purpura with cyclosporine. N Engl J Med. 1985;312:1060-1061.
-
(1985)
N Engl J Med
, vol.312
, pp. 1060-1061
-
-
Hill, W.1
Landgraf, R.2
-
33
-
-
0033019932
-
Identification of mutations in the c-mpl gene in congenital amegakaryocytic thrombocytopenia
-
Ihara K, Ishii E, Eguchi M, et al. Identification of mutations in the c-mpl gene in congenital amegakaryocytic thrombocytopenia. Proc Natl Acad Sci U S A. 1999;96:3132-3136.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 3132-3136
-
-
Ihara, K.1
Ishii, E.2
Eguchi, M.3
|