AKR-501 (YM477) a novel orally-active thrombopoietin receptor agonist

European Journal of Haematology

Volumn 82, Issue 4, 2009, Pages 247-254

  Fukushima Shintani, Mari ^a   Suzuki, Ken Ichi ^a   Iwatsuki, Yoshiyuki ^a   Abe, Masaki ^a   Sugasawa, Keizo ^a   Hirayama, Fukushi ^a   Kawasaki, Tomihisa ^a   Nakahata, Tatsutoshi ^b  

^a ASTELLAS PHARMA INC   (Japan)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

AKR 501; C mpl; NOD SCID mice; Platelets; Thrombopoiesis; Thrombopoietin; YM477

Indexed keywords

AKR 501;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD34 SELECTION; CHIMPANZEE; DIABETES MELLITUS; DRUG EFFECT; DRUG MECHANISM; FETUS LIVER; IN VIVO STUDY; MEGAKARYOPOIESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; SEVERE COMBINED IMMUNODEFICIENCY; THROMBOCYTOPENIA;

ADMINISTRATION, ORAL; ANIMALS; ANTIGENS, CD34; BLOOD PLATELETS; CELL DIFFERENTIATION; FETAL BLOOD; HEMATOPOIESIS; HUMANS; LIVER; MEGAKARYOCYTES; MICE; MICE, INBRED NOD; MICE, SCID; PAN TROGLODYTES; PLATELET COUNT; PLOIDIES; POLYPLOIDY; RECEPTORS, THROMBOPOIETIN; RECOMBINANT PROTEINS; STEM CELL TRANSPLANTATION; THIAZOLES; THIOPHENES; THROMBOPOIETIN;

EID: 61349155417     PISSN: 09024441     EISSN: 16000609     Source Type: Journal    
DOI: 10.1111/j.1600-0609.2008.01198.x     Document Type: Article

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